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mistacarter555
Top-of-the-line Shroomhead
Registered: 08/05/15
Posts: 115
Last seen: 4 years, 10 months
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I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week
#23775751 - 10/27/16 07:03 AM (7 years, 3 months ago) |
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Rispersal, seroquels, all that shit.Shrooms are a 5ht2 agonist right?Turns out risperidone is the opposite;an antagonist at those receptor sites, causing the opposite effect ; receptor upregulation!Literally! I tripped balls 2 days ago, on the comedown, took 9mg risperidone.after the antipsychotic wore off, guess what?tripped again off the same amount, twice as hard, without even 3 days between trips! The visuals are the strongest I've had in my life and tolerance is no longer an issue.Idk why I'm telling you guys this I just think people deserve to know about this tolerance hack.Im not saying abuse it, but it could really come in handy if ya ever wanna kill tolerance!edit:note that I've tried this over 10 times and the results are always the same, completely erased tolerance.Literally, completely, erased.
Edited by mistacarter555 (10/27/16 07:10 AM)
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Kinshino
Restful Soul



Registered: 03/11/13
Posts: 1,122
Loc: 5th Dimension
Last seen: 8 months, 5 days
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: mistacarter555]
#23775779 - 10/27/16 07:24 AM (7 years, 3 months ago) |
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Hmm, very interesting. Personally, I wouldn't like taking an antipsychotic medicine. And you need a prescription for it and all that. It'd be nice if there was a better alternative.
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mistacarter555
Top-of-the-line Shroomhead
Registered: 08/05/15
Posts: 115
Last seen: 4 years, 10 months
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: Kinshino]
#23775796 - 10/27/16 07:35 AM (7 years, 3 months ago) |
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Yeah, antipsychotics are nasty when taken daily.thats why I only take em for about 12 hours, slowly but steadily increasing the dose until I stop abruptly, leaving receptors upregulated.i get them prescribed to me for my bipolar but don't take them, so my supply is basically unlimited from the stored up bottles.
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SonicTitan


Registered: 05/17/16
Posts: 24,068
Last seen: 13 minutes, 33 seconds
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: mistacarter555]
#23775892 - 10/27/16 08:25 AM (7 years, 3 months ago) |
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Doesn't sound safe. Probably would be best to let your body naturally come down.
-------------------- "We are a way for the cosmos to know itself."
 
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The Blind Ass
Bodhi



Registered: 08/16/16
Posts: 26,658
Loc: The Primordial Mind
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: SonicTitan]
#23776428 - 10/27/16 11:37 AM (7 years, 3 months ago) |
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Hmmmm IDK............................Sketch.
Edited by The Blind Ass (10/27/16 11:39 AM)
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The Blind Ass
Bodhi



Registered: 08/16/16
Posts: 26,658
Loc: The Primordial Mind
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: The Blind Ass]
#23776447 - 10/27/16 11:42 AM (7 years, 3 months ago) |
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Medical community has been looking for legit tolerance hacks for decades , so far, nothing magical. Also antagonizing a receptor site doesnt necessarily cause up regulation in the way that an agonist causes down regulation. Still to many variables in your post to belive in the correlation between the two. Each individual shroom can vary somewhat wildly with its alkaloid content, that and you can trip multiple times a week its just not recommended for many many good reasons. Time will tell, ill keeep on eye on this.
-------------------- Give me Liberty caps -or- give me Death caps
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PrimalSoup
hyperspatial illuminations



Registered: 11/17/09
Posts: 13,568
Loc: PNW
Last seen: 1 year, 5 months
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: Kinshino]
#23776964 - 10/27/16 02:35 PM (7 years, 3 months ago) |
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Quote:
Kinshino said: Hmm, very interesting. Personally, I wouldn't like taking an antipsychotic medicine. And you need a prescription for it and all that. It'd be nice if there was a better alternative.
Not going there... 
God gave us tolerance so we'd be encouraged to grow more shrooms, everybody knows that.
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if you stand too close to the machine it'll start to eat youPrimal's simple tested teks and projects: Wheat Prep 2.0 Acidic Tea Tek Potency Project!
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Rebelutionsssss
Mdmazing



Registered: 07/23/14
Posts: 13,137
Loc: San Francisco
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: PrimalSoup]
#23777918 - 10/27/16 07:05 PM (7 years, 3 months ago) |
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we need to grow and have time to change into the person that mushroom has shown us, everyone has their way of tripping but i feel if i trip multiple times a week i just become a confused god person with no direction. break your ego apart to put it back together over time into the person that it should be. doesn't happen so quickly
-------------------- : To define is to confine.
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omnifarious
Stranger


Registered: 02/14/11
Posts: 43
Last seen: 6 years, 8 months
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: Rebelutionsssss]
#23786105 - 10/30/16 04:19 PM (7 years, 2 months ago) |
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id say once every few months is a good amount for me. I haven't in several years and Ive noticed ive been more confused.
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mctaveesh
StrangerInAStrangeLand



Registered: 04/01/16
Posts: 1,118
Last seen: 2 months, 12 days
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: omnifarious]
#23786187 - 10/30/16 04:40 PM (7 years, 2 months ago) |
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Cool thing you figured out. Makes sense but I guess most people don't like those drugs.
If I want to trip 3-4 times a week I'll use DMT. But I agree with Rebelutions... Once a week at most works for me.
--------------------
LogicaL Chaos said: "humans are like cubes, lots of strains but cubes a cube. Not much difference really."
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mistacarter555
Top-of-the-line Shroomhead
Registered: 08/05/15
Posts: 115
Last seen: 4 years, 10 months
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: mistacarter555]
#23786537 - 10/30/16 06:39 PM (7 years, 2 months ago) |
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Yeah that's my plans for any shrooms I pick in the future.I was pretty much just experimenting to see if it'd work and from what I've seen it works pretty well, especially when having tolerance issues wit antidepressants like Zoloft that interfere with the psilocin.And what does it mean when u say that receptors don't work the same with upregulation then down regulation?just curious lol sorry for the bump
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mistacarter555
Top-of-the-line Shroomhead
Registered: 08/05/15
Posts: 115
Last seen: 4 years, 10 months
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: mistacarter555]
#23786595 - 10/30/16 07:01 PM (7 years, 2 months ago) |
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I get why alot of ppl don't like antipsychotics tho.They gave me really bad rls when I took em
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healing
Strangest



Registered: 02/22/11
Posts: 6,565
Loc: the universe, the milky w...
Last seen: 6 years, 6 months
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: mistacarter555]
#23786749 - 10/30/16 08:10 PM (7 years, 2 months ago) |
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Nah man you don't want to fuck around with antipsychotics, especially if you're already on some other medication. Those are some serious risks to take just to avoid waiting a couple weeks for a trip.
-------------------- Open mind, open heart, open book.
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sanchothestoner
Satan's Grandson



Registered: 12/06/11
Posts: 15,623
Loc: Bucketheadland
Last seen: 6 years, 7 months
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: healing]
#23786836 - 10/30/16 08:42 PM (7 years, 2 months ago) |
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that's pretty interesting... but idk man, that doesn't sound safe.
-------------------- I fucking hate you... God damn, I love you... But we both know if we stick together, we'll just tear ourselves apart You are my sunshine, my only sunshine, you make me happy, when skies are grey You are my heroin, but there's an abscess... God damn, I miss the vein!
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topdog82
Death Spirit



Registered: 07/16/10
Posts: 7,992
Loc: California
Last seen: 5 months, 3 days
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Re: I have effectively come up with a tolerance killer allowing me to trip 3-4 times a week [Re: sanchothestoner]
#23786926 - 10/30/16 09:11 PM (7 years, 2 months ago) |
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just stick to DMT. I think you could do pharmahuasca a few times a week? Or just smoke changa after work daily if thats what really floats your boat
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