Home | Community | Message Board


This site includes paid links. Please support our sponsors.


Welcome to the Shroomery Message Board! You are experiencing a small sample of what the site has to offer. Please login or register to post messages and view our exclusive members-only content. You'll gain access to additional forums, file attachments, board customizations, encrypted private messages, and much more!

Shop: Kraken Kratom Red Vein Kratom   Original Sensible Seeds Autoflowering Cannabis Seeds, Bulk Cannabis Seeds   PhytoExtractum Buy Bali Kratom Powder, Kratom Powder for Sale

Jump to first unread post Pages: 1
Some of these posts are very old and might contain outdated information. You may wish to search for newer posts instead.
Offlinejsncrs
DYEL


Registered: 01/16/14
Posts: 1,170
Loc: Mars
Last seen: 3 years, 8 months
How are new organic psychoactive compounds discovered?
    #23769075 - 10/25/16 06:26 AM (7 years, 4 months ago)

I've always wondered this, thought here would be the best place to ask. How do people discover new psychoactive compounds in plants? I know a majority would be due to history of ritualistic use. But is there some scientific method of Analysis that a plant can be put through? Or is it basically just random taste testing?

Extras: Filter Print Post Top
Invisibleellomello
XP
 User Gallery


Registered: 08/11/08
Posts: 2,423
Loc: babilonUSA
Re: How are new organic psychoactive compounds discovered? [Re: jsncrs]
    #23769138 - 10/25/16 07:10 AM (7 years, 4 months ago)

Cool subject! i'd guess most are like you said from documented ritual use.
Then from extracts of plants to concentrate those effects.

Ancient people would sometimes watch animals to see what they eat, and how they reacted.

There is chemistry, where you can take a known compound,
move around some atoms and you have a new compound.

Alexander Shulgin is an example of someone creating thousands of new compounds.

Computers are used to come up with new compounds based on like idk science or something.

:smile:


--------------------
PAY NO ATTENTION TO THE MAN BEHIND THE CURTAIN get back to the garden

some came singing, some come to play, some come for keeping the dark away

Extras: Filter Print Post Top
InvisibleMostly_HarmlessM
wyrd bið ful aræd
Male User Gallery


Registered: 05/12/09
Posts: 5,043
Loc: Perfidious Albion Flag
Re: How are new organic psychoactive compounds discovered? [Re: ellomello]
    #23769154 - 10/25/16 07:23 AM (7 years, 4 months ago)

Shulgin sharing some thoughts

Quote:

One has to be reasonably competent in chemistry, in botany and in pharmacology, all at the same time. If you hope to identify new alkaloids in a plant, you have to take a decade or two, to synthesize reference samples of a few hundred tetrahydroisoquinolines with one through four oxygens on the aromatic ring, with any or all of them having methyl ethers or methylenedioxy ethers attached. And then each of these should be modified from the di-H material to the N-methyl, the 1-methyl or the N, 1-dimethyl homologues. And let's make all the N-oxides. Then the preparation of the dihydro and the aromatic analogues will triple the number of spectra posted up there on the wall.




http://www.cognitiveliberty.org/shulgin/blg/2005/01/juuls-giant-cactus-aka-jewels-giant.html


--------------------
●  EG Rules and Guidelines ● 


|| Lophophora Growers Unite! || Trichocereus Growers Unite! || Stone Eaters - A Soil Revolution ||


You must gather your party before venturing forth.

Extras: Filter Print Post Top
Offlinemandrin13
Stranger
 User Gallery

Registered: 07/08/14
Posts: 1,111
Loc: Socal
Last seen: 3 months, 7 days
Re: How are new organic psychoactive compounds discovered? [Re: Mostly_Harmless]
    #23769168 - 10/25/16 07:38 AM (7 years, 4 months ago)

g-o-o-g-l-e


--------------------
Even Jesus got stoned.

Extras: Filter Print Post Top
InvisibleDualWieldRake
Stranger
 User Gallery

Registered: 07/17/16
Posts: 1,115
Loc: Zone 8b
Re: How are new organic psychoactive compounds discovered? [Re: mandrin13]
    #23769244 - 10/25/16 08:36 AM (7 years, 4 months ago)

finger dip method

Extras: Filter Print Post Top
Offlinejsncrs
DYEL


Registered: 01/16/14
Posts: 1,170
Loc: Mars
Last seen: 3 years, 8 months
Re: How are new organic psychoactive compounds discovered? [Re: DualWieldRake]
    #23770568 - 10/25/16 04:19 PM (7 years, 4 months ago)

I'm currently reading Pikhal which is what lead me to ask this question :lol: Shulgin lived such a cool life

Extras: Filter Print Post Top
Invisibleferrel_human
stone eater
Male User Gallery


Registered: 06/26/09
Posts: 16,359
Loc: Texas
Re: How are new organic psychoactive compounds discovered? [Re: Mostly_Harmless]
    #23770599 - 10/25/16 04:27 PM (7 years, 4 months ago)

Quote:

Mostly_Harmless said:
Shulgin sharing some thoughts

Quote:

One has to be reasonably competent in chemistry, in botany and in pharmacology, all at the same time. If you hope to identify new alkaloids in a plant, you have to take a decade or two, to synthesize reference samples of a few hundred tetrahydroisoquinolines with one through four oxygens on the aromatic ring, with any or all of them having methyl ethers or methylenedioxy ethers attached. And then each of these should be modified from the di-H material to the N-methyl, the 1-methyl or the N, 1-dimethyl homologues. And let's make all the N-oxides. Then the preparation of the dihydro and the aromatic analogues will triple the number of spectra posted up there on the wall.




http://www.cognitiveliberty.org/shulgin/blg/2005/01/juuls-giant-cactus-aka-jewels-giant.html




Now does this guy know how to party or what?


--------------------
Nature is my church and walking through it is gospel. It tells no lies and reveals all to those who look, and listen, closely.
-Karode


Looking for Mimosa tenuiflora seeds. Buttons for trade

Extras: Filter Print Post Top
InvisiblejimmyBbuffet
Registered: 02/20/16
Posts: 558
Re: How are new organic psychoactive compounds discovered? [Re: ferrel_human]
    #23771741 - 10/25/16 10:37 PM (7 years, 4 months ago)

Yup, Sasha was THE MAN. There's a podcast called "the psychedelic salon" with a few of his lectures. Very entertaining.

Extras: Filter Print Post Top
OfflineHerbgrower12
Stranger
 User Gallery

Registered: 08/07/14
Posts: 531
Last seen: 3 years, 8 months
Re: How are new organic psychoactive compounds discovered? [Re: jimmyBbuffet]
    #23774200 - 10/26/16 06:15 PM (7 years, 4 months ago)

Just tell a couple high school kids its "weed" and check the obituaries a few days after.  :awedance: LOL.

Extras: Filter Print Post Top
Jump to top Pages: 1

Shop: Kraken Kratom Red Vein Kratom   Original Sensible Seeds Autoflowering Cannabis Seeds, Bulk Cannabis Seeds   PhytoExtractum Buy Bali Kratom Powder, Kratom Powder for Sale


Similar ThreadsPosterViewsRepliesLast post
* Psychoactive rocks
( 1 2 all )
Aneglakya 4,246 31 06/18/04 03:58 AM
by kadakuda
* Psychoactive Cacti
( 1 2 all )
guitarguy0123 6,318 28 04/03/07 02:15 PM
by guitarguy0123
* Recommended legal psychoactive plants to grow.
( 1 2 3 4 all )
JaguarWarrior101 31,922 66 10/28/08 11:22 PM
by kadakuda
* Are Claviceps Purpurea's fruiting bodies psychoactive? yogafire 1,849 11 04/18/05 07:20 PM
by gnrm23
* The Psychoactive Properties Found in Amanita Species mjshroomer 2,406 7 01/09/04 01:32 PM
by mjshroomer
* Psychoactive discocactus? shamantra 628 4 11/28/05 04:39 PM
by shamantra
* new compound : aeruginascin EvilGir 1,125 3 02/09/05 06:18 PM
by Psiloman
* The Encyckopedia of psychoactive plants GNIOM1498 884 2 05/12/05 11:32 PM
by GNIOM1498

Extra information
You cannot start new topics / You cannot reply to topics
HTML is disabled / BBCode is enabled
Moderator: Mostly_Harmless, A.k.a
375 topic views. 3 members, 8 guests and 5 web crawlers are browsing this forum.
[ Show Images Only | Sort by Score | Print Topic ]
Search this thread:

Copyright 1997-2024 Mind Media. Some rights reserved.

Generated in 0.021 seconds spending 0.004 seconds on 12 queries.