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Offlinesolare
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Registered: 10/15/16
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Why are mushrooms orally active and aya needs harmine
    #23739839 - 10/15/16 11:57 AM (7 years, 3 months ago)

Dear all
I am wondering often its said aya needs harmine to allow DMT to be orally active, but then what in mushrooms allows the psilocybin/psilocin to cross the blood brain barrier and not be degraded by MAO? Do psilocybe mushrooms have an MAO inhibitor inherent?


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OfflineXiliad
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Registered: 11/27/12
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Re: Why are mushrooms orally active and aya needs harmine [Re: solare]
    #23739872 - 10/15/16 12:14 PM (7 years, 3 months ago)

No mushrooms do not have MAOI inherent, it's because psilocybin/psilocin won't be broken down by the enzymes the same way DMT will, so you need the MAOI to allow pure DMT to pass through without getting broken down


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