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Dmt_psilocybin
White Male


Registered: 09/08/16
Posts: 467
Loc: shroom capital of the U.S
Last seen: 7 years, 1 month
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Psilocybin changed high from THC and other cannabinoids
#23689980 - 09/29/16 10:17 AM (7 years, 3 months ago) |
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After my first mushroom trip which was 1/8 dried, it has permanently changed the way my body accepts THC and possibly other cannabinoids. Now every time i smoke weed, it feels like i just took shrooms, and makes it undesirable and i haven't been able to normally function on it.
However i found this very strange, if i get my cannabis tolerance up, that shroomey feeling goes away. This especially doesn't make sense to me as psilocin effects the serotonin receptors and THC effects the anandamide receptors. However it could be other cannabinoids that have been altered besides THC. But dabbing 70% THC shatter has intensified this so much i get visuals like i'm tripping on shrooms. I believe somehow psilocin, dimethyltryptamine, and tetrahydrocannabinol are ll directly related in the brain somehow, but we just don't know it yet.
I've even written a paper about it for my psych 1101 class and had a chat with my professor. He was quite interested in this but yet still couldn't figure out why this would be.
If anyone has any thoughts, theories, or if this has happened to them please feel free to share
-------------------- MDMA is over rated
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420Leprechaun
Psychonaut



Registered: 09/22/16
Posts: 25
Last seen: 1 year, 10 months
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Dmt_psilocybin]
#23690019 - 09/29/16 10:26 AM (7 years, 3 months ago) |
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How long ago was your first shroom trip? If it was recent then the possibility of flashback scenarios to your mushroom trip are extremely possible. This once happened to me about 3 days after a mushrooms trip and i usually like to trip on an eighth but am a very avid pot smoker. And one time after sex with my girlfriend at the time and I was driving back to my town, i hit the pipe, sex increases your serotonin levels as well, I hit the pipe probably after it had been 10 minutes after I left her house and I held it in, then I got really light headed (which is rare because I smoke 7-8 grams of medical dro a day). Next thing i know my dashboard and steering wheel, everything around me was breathing like a mushroom trip and I was like wtf? Have not ever experienced that since then, although I wish I could because that was an awesome feeling, just a little sketchy while doing 75 mph at night while it is raining lmfao. But if this was a recent mushroom experience im sure it will pass. Mushrooms also open you up to more intellectual thought similar to pot but on a deeper level, so maybe you are getting the same thought processes and worldly views, comparing the two experiences to one another.
-------------------- "Too weird to live, too rare to die." "One pill makes you taller, and one pill makes you small, and the one's that mother gives you, don't do anything at all, go ask Alice.."
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Dmt_psilocybin
White Male


Registered: 09/08/16
Posts: 467
Loc: shroom capital of the U.S
Last seen: 7 years, 1 month
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Re: Psilocybin changed high from THC and other cannabinoids [Re: 420Leprechaun]
#23690227 - 09/29/16 11:26 AM (7 years, 3 months ago) |
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My first mushroom trip was about a year and a half ago. It still happens every time if i don't have a high tolerance. It was cool at first and after about 10 times later it got really annoying and isn't as pleasant as it used to be. I had a really high tolerance smoking multiple times a day for about 6 months and i thought it went away. and after a month of dabbing one time the next time i smoked it came right back.
-------------------- MDMA is over rated
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420Leprechaun
Psychonaut



Registered: 09/22/16
Posts: 25
Last seen: 1 year, 10 months
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Dmt_psilocybin]
#23690372 - 09/29/16 12:18 PM (7 years, 3 months ago) |
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That is absolutely insane, did you smoke bud whenever you had your first mushroom trip? Your mind could be playing tricks on you or some how creating a relationship between the thc and psylocin. Kind of like when you eat smell something and your mind takes you back to the place where you first smelled it. Also how old are you and what do you get when you smoke bud now? Are you experiencing visual hallucinations, or are you getting the breathing world, over active thought processes or just everything tripping major balls?
-------------------- "Too weird to live, too rare to die." "One pill makes you taller, and one pill makes you small, and the one's that mother gives you, don't do anything at all, go ask Alice.."
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Dmt_psilocybin
White Male


Registered: 09/08/16
Posts: 467
Loc: shroom capital of the U.S
Last seen: 7 years, 1 month
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Re: Psilocybin changed high from THC and other cannabinoids [Re: 420Leprechaun]
#23690390 - 09/29/16 12:24 PM (7 years, 3 months ago) |
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Yeah i actually smoked like 6 bowls coming up and it made the first shroom trip insane. Now smoking takes me back to shroom world and when i dab or some heavily i get visuals of everything slightly moving and breathing. Most of the time i can't smoke to much or it's really intense. It's gotten super annoying that i can barely smoke cannabis anymore. Usually it's only the head high part of shrooms everytime i smoke and my vision is pretty disorientated, even off of one bong rip of low quality bud. I used to smoke some of the best buds you've probably seen in your life and now that just gets me insanely high off of a few bong rips. I wouldn't really like sharing my age i was pretty young on my first trip though.
-------------------- MDMA is over rated
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Dmt_psilocybin
White Male


Registered: 09/08/16
Posts: 467
Loc: shroom capital of the U.S
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Dmt_psilocybin]
#23690395 - 09/29/16 12:26 PM (7 years, 3 months ago) |
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For instance i smoked one small bong rip an hour ago and my brain is still in mushroom world minorly though.
-------------------- MDMA is over rated
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AstralAndrew
Shroomy



Registered: 10/05/14
Posts: 2,569
Loc: Canada
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Dmt_psilocybin]
#23690677 - 09/29/16 01:45 PM (7 years, 3 months ago) |
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What's your diet and exercise life like? Any antidepressants like maoi's?
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     "The opposite for courage is not cowardice, it is conformity. Even a dead fish can go with the flow." - Jim Hightower
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nooneman


Registered: 04/24/09
Posts: 14,564
Loc: Utah
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Dmt_psilocybin]
#23690740 - 09/29/16 02:01 PM (7 years, 3 months ago) |
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The 5HT2A and cannabinoid receptors do actually influence each other. There was a paper about this a while back. I don't remember the exact details, something about them being next to each other or sharing some biological component or something like that.
Anyway, the point is there is actually a known relationship between 5HT2A and cannabinoid receptors.
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Peyote Road
Stranger

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Re: Psilocybin changed high from THC and other cannabinoids [Re: nooneman]
#23691125 - 09/29/16 04:17 PM (7 years, 3 months ago) |
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wow your professor couldnt figure it out shows how much education is worth in this country.
the answer is obvious, mushrooms open up your mind. after certain pathways are opened up, they may not close back down. marijuana being a psychedelic itself, which puts you in a heightened state of awareness, puts you back in touch with these parts of your mind.
psychedelic flashbacks when smoking pot, or drugs changing your mind are nothing new. shaman have known about this for thousands of years, but modern professors cant figure it out, lol.
-------------------- The path of the herbalist is to open ourselves to nature in an innocent and pure way. SHe in turn will open her bounty and reward us with many valuable secrets. May the earth bless you. - Michael Tierra
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sunshine
Sin18DwireWuTang


Registered: 04/03/04
Posts: 43,592
Loc: higher plane of sex
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Peyote Road]
#23691133 - 09/29/16 04:19 PM (7 years, 3 months ago) |
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I basically trip when I get high on anything. Even alcohol.
-------------------- One Love True Indeed. Have Good Trips. Mike/sunshine's mom.
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olson
Stranger

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Re: Psilocybin changed high from THC and other cannabinoids [Re: nooneman]
#23691184 - 09/29/16 04:43 PM (7 years, 3 months ago) |
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Yep I've noticed this too. As one of the above posters mentioned the cannabinoid receptors actually link up with the 5-HT2a receptors when they're activated leading to 5-HT2a activation. Maybe once you're primed with psychedelics this effect is much more pronounced. Or it could be purely a psychological phenomenon. It could be that once the veil has been lifted you don't quite see things the same way again and weed accentuates that. Who knows...
--------------------
Kinesin, a motor protein, shuttling a vesicle full of cargo such as glucose or even neurotransmitters across a cell. This little guy struts along the microtubule using ATP as fuel.
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Peyote Road
Stranger

Registered: 09/02/15
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Re: Psilocybin changed high from THC and other cannabinoids [Re: sunshine]
#23691237 - 09/29/16 05:05 PM (7 years, 3 months ago) |
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Quote:
sunshine said: I basically trip when I get high on anything. Even alcohol.
same here, after my mind has opened up anything that alters it shows me some information about how it works. ive heard people say all drugs are psychedelic drugs. i agree with the spirit of that statement, although of course there are still differences.
-------------------- The path of the herbalist is to open ourselves to nature in an innocent and pure way. SHe in turn will open her bounty and reward us with many valuable secrets. May the earth bless you. - Michael Tierra
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sunshine
Sin18DwireWuTang


Registered: 04/03/04
Posts: 43,592
Loc: higher plane of sex
Last seen: 5 years, 19 hours
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Peyote Road]
#23691270 - 09/29/16 05:11 PM (7 years, 3 months ago) |
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I don't exactly trip in that sense but everything is trippy.
-------------------- One Love True Indeed. Have Good Trips. Mike/sunshine's mom.
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Buger
Perpetual harvester



Registered: 09/04/16
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Re: Psilocybin changed high from THC and other cannabinoids [Re: sunshine]
#23691298 - 09/29/16 05:21 PM (7 years, 3 months ago) |
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Post tramatic ha.
B
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AstralAndrew
Shroomy



Registered: 10/05/14
Posts: 2,569
Loc: Canada
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Peyote Road]
#23691351 - 09/29/16 05:41 PM (7 years, 3 months ago) |
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Quote:
Peyote Road said:
Quote:
sunshine said: I basically trip when I get high on anything. Even alcohol.
same here, after my mind has opened up anything that alters it shows me some information about how it works. ive heard people say all drugs are psychedelic drugs. i agree with the spirit of that statement, although of course there are still differences.
This^
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     "The opposite for courage is not cowardice, it is conformity. Even a dead fish can go with the flow." - Jim Hightower
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Dmt_psilocybin
White Male


Registered: 09/08/16
Posts: 467
Loc: shroom capital of the U.S
Last seen: 7 years, 1 month
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Re: Psilocybin changed high from THC and other cannabinoids [Re: AstralAndrew]
#23691774 - 09/29/16 07:10 PM (7 years, 3 months ago) |
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Quote:
What's your diet and exercise life like? Any antidepressants like maoi's?
I am fairly healthy i eat fast food occasionally. I consider myself pretty physically fit i surf and have a weekly weight lifting schedule. I may occasionally consume maoi's without knowing, but i don't use anti depressants.
Quote:
Anyway, the point is there is actually a known relationship between 5HT2A and cannabinoid receptors.
Really? i would love to read that paper. I couldn't find anything about that but very interesting i did not know that. Kind of how dmt and psilocin influence the serotonin receptors.
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wow your professor couldnt figure it out shows how much education is worth in this country.
psychedelic flashbacks when smoking pot, or drugs changing your mind are nothing new. shaman have known about this for thousands of years, but modern professors cant figure it out, lol.
I see where you are coming from and he knows about flashbacks however thats not what i'm talking about. My psych professors name is michael torrelo and is one of, not the most intelligient person iv'e ever met. I want to know the exact change in my brain and that's what i asked him. He's done neurological studies in the 80's-90's at harvard and yale, also teaching at harvard. Although i do agree about the education in this country, complete joke. However my professors so far have not been like that.
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Maybe once you're primed with psychedelics this effect is much more pronounced. Or it could be purely a psychological phenomenon.
Could very well be. Maybe the memory of how cannabis effected the trip could permanently be brought up every time i smoke. Who even knows.
Quote:
same here, after my mind has opened up anything that alters it shows me some information about how it works. iv'e heard people say all drugs are psychedelic drugs.
I definitely agree with this statement. However psilocin has seemed to change specifically my reaction to cannabis. And my brain won't show me why  Perhaps meditation, atral projection might reveal the reason. Obviously i have no idea what your take is on either of those things and you could just think they're bullshit.
-------------------- MDMA is over rated
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UniverseOfTheMind8
Stranger

Registered: 02/16/16
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Dmt_psilocybin]
#23693472 - 09/30/16 09:06 AM (7 years, 3 months ago) |
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The exact same thing happened to me. Every time I smoke weed I go to a very shroomey headspace and if I dab I completely full on trip. I thought just not taking shrooms for awhile would help, but I haven't taken them for like four months and nothing has changed. It really sucks because shrooms always put me into a really dark and doomish type place, so now THC does too. Shroom trips can be pretty cool, but when I smoke weed I wanna actually be able to act normal and socialize with people haha.
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UniverseOfTheMind8
Stranger

Registered: 02/16/16
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Re: Psilocybin changed high from THC and other cannabinoids [Re: UniverseOfTheMind8]
#23693496 - 09/30/16 09:13 AM (7 years, 3 months ago) |
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I've also never smoked weed on shrooms, so I don't really think it has much to do with the weed you smoked on your first trip.
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majicman30
naturejunkie



Registered: 09/22/14
Posts: 749
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Re: Psilocybin changed high from THC and other cannabinoids [Re: Dmt_psilocybin]
#23693510 - 09/30/16 09:21 AM (7 years, 3 months ago) |
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In my openion this is the MIND playing a trick on you and maybe the weed just felt like the shrooms a little before u even done the shrooms make sense. I thought not to, well not to u, but makes perfect sense to me.(lol) I have experienced these types of experiences, but can tell u from my perspective this is just normal. The first time I smoked weed it Mucked me up WAY more than Shrooms did. For a short time anyhow. I hope things get better for you though O.P. Peace & Love
-------------------- [ /url ]    [url=http://files.shroomery.org/files/16-12/893004217-IMG_4581.
Edited by majicman30 (09/30/16 09:23 AM)
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Dmt_psilocybin
White Male


Registered: 09/08/16
Posts: 467
Loc: shroom capital of the U.S
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Re: Psilocybin changed high from THC and other cannabinoids [Re: UniverseOfTheMind8]
#23693666 - 09/30/16 10:27 AM (7 years, 3 months ago) |
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Quote:
The exact same thing happened to me. Every time I smoke weed I go to a very shroomey headspace and if I dab I completely full on trip. I thought just not taking shrooms for awhile would help, but I haven't taken them for like four months and nothing has changed. It really sucks because shrooms always put me into a really dark and doomish type place, so now THC does too. Shroom trips can be pretty cool, but when I smoke weed I wanna actually be able to act normal and socialize with people haha.
You just described exactly what i'm talking about. Shrooms also tend to put me in a darkish place. Not every time, but weed puts me in this place now as well. Sometimes i'll get these recurring weird close eyed visuals of these weird faces going around in a circle. That's probably just me though lol.
And yeah when i dab i full on trip.
Quote:
In my openion this is the MIND playing a trick on you and maybe the weed just felt like the shrooms a little before u even done the shrooms make sense. I thought not to, well not to u, but makes perfect sense to me.(lol) I have experienced these types of experiences, but can tell u from my perspective this is just normal. The first time I smoked weed it Mucked me up WAY more than Shrooms did. For a short time anyhow. I hope things get better for you though O.P. Peace & Love
Hey man it totally could be. Thanks though appreciated
-------------------- MDMA is over rated
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