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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Psychedelics to mitigate sleep deprivation
    #23681530 - 09/26/16 10:26 PM (7 years, 5 months ago)

I've been up for about three days, I actually don't remember when I last slept, and I need to stay awake for the next 12-18 hours, unfortunately. I started researching how sleep deprivation affects the brain, apparently ADD like effects begin to present as the prefrontal cortex becomes less active. Modafinil stops working at around the seventy two hour mark according to research conducted on fighter pilots. Amphetamines work for a certain period of time, but the benefit:cost ratio rapidly deteriorates as sleep deprivation progresses.

Remembering an fmri study on the neurological effects of psilocybin (massive increase in brain activity across almost all regions), I decided to micro-dose some mushrooms I've been saving for a rainy day, 0.75g of cyanescens to keep me awake and my brain active w/ 2mg etizolam to mitigate anxiety due to increased stress hormones, and 100mg aspirin for the headache, and finally loperamide to keep my GI system intact.

Either way this goes, it's going to be interesting. Considering my alternatives, this was my best option and I absolutely do not recommend that anyone follow suit; however, I will be recording this experience as I think it might prove valuable, whether it ends up as a train wreck or succeeds as a crazy-ass shot in the dark experience. Not to say that if this succeeds, my hypothesis that micro-dosing psychedelics will be validated, as I'm only one person in a non-controlled environment, but it will serve as a foothold for deeper exploration of the effects of psychedelics on sleep deprivation IMO.

So, T+15mins in and I'm feeling much better. Headache has completely gone away.

I'll only edit the OP to provide updates as to not spam the pub. The reason I didn't post this in ODD is that posts in that subforum are not indexed by google :shrug:.

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Invisibletdubz
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681532 - 09/26/16 10:27 PM (7 years, 5 months ago)

Can you not sleep because you can't sleep or are you forcing yourself to stay awake? I got some good med recommendations if you are a true insomniac.

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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Re: Psychedelics to mitigate sleep deprivation [Re: tdubz]
    #23681536 - 09/26/16 10:29 PM (7 years, 5 months ago)

Quote:

tdubz said:
Can you not sleep because you can't sleep or are you forcing yourself to stay awake? I got some good med recommendations if you are a true insomniac.




I have enough drugs to knock out a rhino, I'm forcing myself to stay awake because of a contractual obligation I absolutely can not break.

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InvisibleAdden
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Registered: 06/04/03
Posts: 39,201
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681540 - 09/26/16 10:32 PM (7 years, 5 months ago)

I use mushrooms before I go hiking. It helps loosen me up and get into my groove easier. I also find it helps me be more aware of bad footholds, random holes and helps with the ability to make decisions faster and more definitive. After my hike, I'm sore, but by then the drugs are wearing off and I'm tired so I feel good and then cannabis makes me feel great.

I've done this before when I was already up 36+ hours, and just needed 10 to 12 hours disappear to get back on my sleep schedule. It helps prevent sleep turning into a long cat nap and then I'm awake and pissed even longer. I find mushrooms better when I'm slightly high on them and I think it's because of color changes and perception. My vision also gets better while tripping. It makes ocular pressure go away too, along with non-dehydration related headaches, they just disappear.

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InvisiblePatrickKn
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681559 - 09/26/16 10:40 PM (7 years, 5 months ago)

It's an interesting theory, but useless without data. You could claim wakefulness from the mixture of drugs, but your mindstate could also be fooling you into thinking you're more coherent than you actually are.

At three days of no sleep, your brain is going to begin catching sleep where it can, in tiny amounts lasting seconds. It will do this with our without your conscious permission. If you're keeping yourself up in order to finish projects, you're better off catching a nap here and there instead of pushing through. Unless the tasks are completely robotic in nature, your awareness is impaired to the point that your losing more hours starting awake than you are taking a nap and doing a task more effectively.

I like to take melatonin after any use of psychedelics. Maybe consider it when you're ready to sleep, it seems to make me less groggy the day after. Moreso than alcohol, benzos and Ambien might.

Edited by PatrickKn (09/26/16 10:41 PM)

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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Re: Psychedelics to mitigate sleep deprivation [Re: PatrickKn]
    #23681583 - 09/26/16 10:48 PM (7 years, 5 months ago)

Quote:

PatrickKn said:
It's an interesting theory, but useless without data. You could claim wakefulness from the mixture of drugs, but your mindstate could also be fooling you into thinking you're more coherent than you actually are.

At three days of no sleep, your brain is going to begin catching sleep where it can, in tiny amounts lasting seconds. It will do this with our without your conscious permission. If you're keeping yourself up in order to finish projects, you're better off catching a nap here and there instead of pushing through. Unless the tasks are completely robotic in nature, your awareness is impaired to the point that your losing more hours starting awake than you are taking a nap and doing a task more effectively.

I like to take melatonin after any use of psychedelics. Maybe consider it when you're ready to sleep, it seems to make me less groggy the day after. Moreso than alcohol, benzos and Ambien might.




All true. Although I'm trying to avoid passing out, not exactly going for peak mental performance. Like I said, shot in dark :shrug:. If this goes well I'm going to allocate some time to compile peer-reviewed medical journals related to the subject.

Anyways, starting to see tracers and beginning to experience the slightest euphoria. I also have noticed significant broncodilation and feel much better/awake than I did when I typed out the OP. Colors are becoming more vivid. This is going to be fun.

:awecid:

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Invisibletyrannicalrex
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681692 - 09/26/16 11:22 PM (7 years, 5 months ago)

holy cow dude! Be safe. :grin:


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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Re: Psychedelics to mitigate sleep deprivation [Re: tyrannicalrex]
    #23681840 - 09/27/16 12:20 AM (7 years, 5 months ago)

So, I took out an hour to take an IQ test to get some data.



Objects were morphing on the page halfway through.

Quote:

tyrannicalrex said:
holy cow dude! Be safe. :grin:




For sure man!

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Invisibletyrannicalrex
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681872 - 09/27/16 12:41 AM (7 years, 5 months ago)

so cerebral society is the site for this test?


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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Re: Psychedelics to mitigate sleep deprivation [Re: tyrannicalrex]
    #23681887 - 09/27/16 12:47 AM (7 years, 5 months ago)

- http://www.cerebrals.org/jcti/index.html

Quote:

The JCTI is a computerized nonverbal intelligence test designed with figurative items which don’t require acquired knowledge. The JCTI has been developped so that the number of items (up to 52) is individually adapted according to the test-taker’s performance. Thanks to the nonverbal nature of its items, this test is suitable for testing persons without cultural bias. It yields with a Reasoning Index (RIX), an age-referenced standard score that uses a mean of 100, and 15 points per standard deviation.

Along with excellent Alpha reliability coefficients over ages (ranged from .92 to .96 in persons aged 7:5 years to 62 years; the value for the entire sample gathering 1,020 persons was .95), the JCTI RIX has also demonstrated high validity. As a result of factor analysis for construct validity, the JCTI showed to be very highly loaded on the general ability factor (.88) that latently linked it to the subscales of the Scholastic Assessment Test-Recentered (SAT-I) and proved to be the most loaded in inductive reasoning (.96).

Analyses also demonstrated that the correlations with other measures of cognitive ability were within the expectations and higher magnitudes of Pearson’s coefficient were observed with nonverbal tasks. As an example, the JCTI RIX and the Performance IQ of the Wechsler Adult Intelligence Scale (WAIS) were correlated at .74 (N=50). Furthermore, the JCTI RIX was seen to be very closely related to the mathematical scale of the SAT-I at .82 (N=99). Significant correlations were also observed with general (r=.67 with WAIS FSIQ, N=50) and crystallized intelligence measures (r=.57 with the JCCES CEI, N=103). According to these findings the JCTI RIX can be regarded as a valid and reliable measure that could be used in the field of education and psychology.



Edited by falsereality (09/27/16 12:47 AM)

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OfflineTrippedytrip
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Re: Psychedelics to mitigate sleep deprivation [Re: tdubz]
    #23681906 - 09/27/16 12:59 AM (7 years, 5 months ago)

What can you recommend for insomnia :smile: ?

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Invisibletyrannicalrex
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681907 - 09/27/16 12:59 AM (7 years, 5 months ago)

well this is embarrassing. 78, 74, 84.:shrug:


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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Re: Psychedelics to mitigate sleep deprivation [Re: tyrannicalrex]
    #23681914 - 09/27/16 01:02 AM (7 years, 5 months ago)

Quote:

tyrannicalrex said:
well this is embarrassing. 78, 74, 84.:shrug:




No way dude, maybe try again in the morning? Also, the test takes around an hour to complete all 52 questions. If you are an RN you have to be north of 100.

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Invisibletdubz
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Re: Psychedelics to mitigate sleep deprivation [Re: Trippedytrip]
    #23681953 - 09/27/16 01:30 AM (7 years, 5 months ago)

flurazepam....for severe insomnia it is a benzo although not very recreational, much different than klonopin and Xanax which could be considered as addicting. It serves it's purpose to make you go to sleep and keep you asleep. This is better than any of the Z drugs I have tried Lunesta, Ambien, ect this benzo does not get you high it put's an keeps you to sleep. Doxepin is another drug I use if I have to and I usually do, it's a TCA anti depressant that works particularly well for insomnia. These drugs are like last resort if nothing else works for you OTC or otherwise.

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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Re: Psychedelics to mitigate sleep deprivation [Re: tdubz]
    #23681962 - 09/27/16 01:35 AM (7 years, 5 months ago)

I like to mix trazadone, etizolam, alcohol and weed, along with a line of anhydrous melatonin (burns like a motherfucker though). Obviously this is a dangerous combo that has killed people in the past, but I know my limits :shrug:. Wouldn't recommend it to anyone, it's just worked well for me over the last five years.

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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681968 - 09/27/16 01:40 AM (7 years, 5 months ago)

So, guess my shot in the dark hit its target. I feel pretty damn good for being as sleep deprived as I am. Next time I'm going to take around 75ug of lsd and see what happens.

About to hit a bowl and kick things back up again :grin:.

Edited by falsereality (09/27/16 01:40 AM)

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Invisibletdubz
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681972 - 09/27/16 01:43 AM (7 years, 5 months ago)

trazadone is crap for sleep an so is etiz mind you this would probably work for anyone having mild sleep problems, but for severe insomnia etiz is not going to work that well which has a short half life vs flurazepam with a very long half life extending into the next day. I would say most anti depressants r crap but doxepin is better than trazadone IMO having tried both and well etiz leans more towards the recreational side than having any medicinal purpose. Again just my opinion having tried all those.

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Invisiblefalsereality


Registered: 04/01/13
Posts: 4,112
Re: Psychedelics to mitigate sleep deprivation [Re: tdubz]
    #23681977 - 09/27/16 01:51 AM (7 years, 5 months ago)

Quote:

tdubz said:
trazadone is crap for sleep an so is etiz mind you this would probably work for anyone having mild sleep problems, but for severe insomnia etiz is not going to work that well which has a short half life vs flurazepam with a very long half life extending into the next day. I would say most anti depressants r crap but doxepin is better than trazadone IMO having tried both and well etiz leans more towards the recreational side than having any medicinal purpose. Again just my opinion having tried all those.




I only have sleep initiation problems, once I'm out, I'm out. So, in order to get more REM/SWS I use relatively short acting drugs to initiate sleep. I'm just saying it works excellently for me 100% of the time. Your physiology is probably different, drugs effect everyone differently.

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Invisibletdubz
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23681985 - 09/27/16 01:55 AM (7 years, 5 months ago)

Yeah I got MAJOR sleep problems it has taken a lot of trial an error to find something that works for me. These drugs are not like Ambien an Lunesta which may or may not work an could also get you high, they put you to sleep an that's all.

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InvisibleMoonshoe
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Re: Psychedelics to mitigate sleep deprivation [Re: falsereality]
    #23682008 - 09/27/16 02:11 AM (7 years, 5 months ago)

Um... if you are forcing yourself to stay up to finish some contract work, maybe get off the shroomery and do the work, or get some sleep.

Staying up for 3 days is causing serious brain disruptions. You will go psychotic soon. And you are already functioning mentally  severely impaired.

It obviously makes sense to get a good 8 hours of sleep and then get back to work when you wake up.

At least a nap of 3-4 hours minimum. Zero shroomery time, obviously.


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Everything I post is fiction.

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