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ShroomDoom
Friend of the Medicine



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Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. 1
#23593307 - 08/30/16 11:28 AM (7 years, 4 months ago) |
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Pharma & Healthcare 8/30/2016 @ 9:58AM 5,557 Views The DEA Is Placing Kratom And Mitragynine On Schedule I David Kroll , CONTRIBUTOR
The kratom plant, Mitragyna speciosa, produces medicinally important alkaloids that are increasingly known to be of potential medical benefit, but with questionable abuse potential. Photo credit: Shutterstock
The U.S. Drug Enforcement Agency has filed a notice of intent (PDF) to place the southeast Asian plant called kratom to the most restrictive classification of the Controlled Substances Act. The plant, Mitragyna speciosa, and its two primary constituents, mitragynine and 7-hydroxymitragynine, will be temporarily placed onto Schedule I on September 30, according to a filing by the DEA at 8:45 am Eastern time today. The full announcement is scheduled to be published in the Federal Register tomorrow, August 31.
Various forms of kratom and teas made from the plant’s leaves are sold in cafes and on the internet. Their primary effect is to provide a short-lived peaceful and calm feeling that is described as pleasant. Consistent with this effect being opioid-like, anecdotal reports indicate that some users have used kratom to successfully recover from physical and psychological dependence on prescription opioids and heroin. Comments on my last report on kratom have also indicated the successful use of teas made from the plant in managing chronic pain without the side effects and addictive potential of prescription opioids like oxycodone, hydrocodone and morphine.
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In the last two months, published research has pointed to why kratom might be a useful and safer alternative to prescription opioids. The main component of the herb, the alkaloid mitragynine, and its metabolite and oxidation product, 7-hydroxymitragynine, produce an effect on the mu subtype of opioid receptors away from many of the mechanisms that cause many opioid side effects. These alkaloids are now shown to be so-called G-protein biased ligands at the mu opioid receptor. This effect minimizes the engagement of an intracellular protein called beta-arrestin that among other effects, causes a reduction in opioid receptors on the surface of cells, leading to the tolerance and dose escalation commonly seen with prescription opioids.
The CDC has reported in July that kratom can be abused and that poison control centers have received over 660 calls between 2010 and 2015 regarding kratom intoxication. This report has been criticized as being relatively inconsequential given the small number of cases when compared with other legal and illegal intoxicants. In some cases listed as kratom intoxication, other illicit drugs were taken by the individuals.
The North Carolina state legislature recently decided not to restrict and criminalize use and sale of kratom–limiting it only to buyers over age 18–because of personal testimonials to the benefits of kratom teas. With the federal intent to place the herb and its bioactive constituents on Schedule I, the DEA is ignoring the increasing scientific literature on a potential beneficial medical use of the plant. Schedule I classification, used for drugs with no known medical use and high abuse potential, will certainly make subsequent research on the plant more difficult.
I’ll update this post with expert commentary as more information becomes available.
For more health and pharmaceutical news and commentary, follow me on Twitter@DavidKroll, or here atForbes.com.
MORE PHARMA & HEALTHCARE STORIES © 2016 Forbes Media LLC. All Rights Reserved. AdChoices AdChoices Privacy Statement Terms and Conditions Contact Us Jobs At Forbes Reprints & Permissions Forbes Press Room Advertise http://www.forbes.com/sites/davidkroll/2016/08/30/dea-to-place-kratom-mitragynine-on-schedule-i-premature-move-may-compromise-research-benefits/#2fd5fc307924
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Edited by ShroomDoom (08/30/16 11:37 AM)
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undersativaskies
blue ridgerepresent



Registered: 05/13/06
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Loc: cville
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: ShroomDoom]
#23593334 - 08/30/16 11:35 AM (7 years, 4 months ago) |
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Those bastards.
-------------------- The wolves howl, the sheep dwell, and the fool casts his whom.
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Mental Taco



Registered: 07/02/14
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: undersativaskies]
#23593350 - 08/30/16 11:42 AM (7 years, 4 months ago) |
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Why!? Kratom has great potential in the midst of this opioid epidemic. Guess they would rather have addicts dependant on pharma than to have access to all natural alternatives.
-------------------- Did you not know that the royal hunting grounds are always forbidden?
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ShroomDoom
Friend of the Medicine



Registered: 06/07/04
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: Mental Taco]
#23593414 - 08/30/16 11:58 AM (7 years, 4 months ago) |
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It's time to push for medical Kratom programs on a state level.
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LuSiD enthusiast
Stranger

Registered: 03/14/13
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: ShroomDoom]
#23593552 - 08/30/16 12:43 PM (7 years, 4 months ago) |
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This is guaranteed? Like it's actually happening?
-------------------- I'm addicted to coke, weed, booze, ludes and speed. Not LSD, you can't get addicted to LSD, it was built by scientists. I ain't got no demons that gonna get woke. In erowid we trust. Just take your damn pills and don't ask any questions, you'll be fine.
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Headrush


Registered: 05/20/16
Posts: 338
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: ShroomDoom]
#23593593 - 08/30/16 12:52 PM (7 years, 4 months ago) |
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DEA should just declare war against everything in nature. Stupid fuckers just power hungry and greedy. Cannabis and Kratom can help so many people that are dependent on big pharma industry's poison. Makes me sick.
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BoomBoom
Nuke worker-Its a blast!



Registered: 01/23/10
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: Headrush]
#23593634 - 08/30/16 01:03 PM (7 years, 4 months ago) |
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Wtf? Kratom got me off oxy. Wtf...
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Achillita
Back to the basics



Registered: 05/26/14
Posts: 4,565
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: BoomBoom]
#23593660 - 08/30/16 01:12 PM (7 years, 4 months ago) |
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https://www.dea.gov/divisions/hq/2016/hq083016.shtml
AUG 30 (WASHINGTON) - The Drug Enforcement Administration (DEA) today announced its intention to place the active materials in the kratom plant into Schedule I of the Controlled Substances Act in order to avoid an imminent hazard to public safety. Mitragynine and 7-hydroxymitragynine are found in kratom, which is a tropical tree indigenous to Thailand, Malaysia, Myanmar, and other areas of Southeast Asia. The announcement was made in the U.S. Federal Register and can be found by following this link.
Kratom is abused for its ability to produce opioid-like effects and is often marketed as a legal alternative to controlled substances. Law enforcement nationwide has seized more kratom in the first half of 2016 than any previous year and easily accounts for millions of dosages intended for the recreational market, according to DEA findings. In addition, kratom has a high potential for abuse, has no currently accepted medical use in treatment in the United States, and has a lack of accepted safety for use under medical supervision. These three factors constitute a Schedule I controlled substance according to the Controlled Substances Act passed by Congress in 1970.
Kratom has been seized by law enforcement in various forms, including powder, plant, capsules, tablets, liquids, gum/resin, and drug patch. Because the identity, purity levels, and quantity of these substances are uncertain and inconsistent, they pose significant adverse health risks to users.
From February 2014 to July 2016, over 55,000 kilograms of kratom material were encountered by law enforcement at various ports of entry within the United States. Additionally, another 57,000+ kilograms of kratom material offered for import into the United States between 2014 and 2016 are awaiting an FDA admissibility decision. Together, this material is enough to produce over 12 million doses of kratom. The FDA has also warned the public not to use any products labeled as containing kratom due to concerns about toxicity and potential health impacts. In addition, FDA has issued and updated two import alerts related to kratom products. Kratom has been on DEA’s list of drugs and chemicals of concern for several years.
The American Association of Poison Control Centers identified two exposures to kratom from 2000 and 2005. Between 2010 and 2015, U.S. poison centers received 660 calls related to kratom exposure. The Center for Disease Control (CDC) found that kratom abuse leads to agitation, irritability, tachycardia, nausea, drowsiness, and hypertension. Health risks found in kratom abusers include hepatotoxicity, psychosis, seizure, weight loss, insomnia, tachycardia, vomiting, poor concentration, hallucinations, and death. DEA is aware of 15 kratom-related deaths between 2014 and 2016.
Well shit.
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Konyap

Registered: 06/30/07
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: Achillita]
#23593666 - 08/30/16 01:15 PM (7 years, 4 months ago) |
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peices of shit
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nuentoter
conduit



Registered: 09/17/08
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: Headrush] 2
#23593675 - 08/30/16 01:17 PM (7 years, 4 months ago) |
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Except in the cases of Cannabis sativa Catha edulis Erythroxylum coca Lophophora williamsi Papaver somniferum Psilocybin containing Mushroom Tabernanthe iboga Ipomoea aquatica Salvia Divinorum Daturas Ephedra sinica or Ma Huang Mimosa Hostilis Morning Glory Syrian Rue
the noxious plant lists for the states are pages and pages long. so yeah, i think we like to tell god we trust him, but really we quietly believe he's a sadist putting all these dangerous drugs out there for us to explore.
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The geometry of us is no chance. We are antennae, we are tuning forks, we are receiver and transmitters of all energy. We are more than we know. - @entheolove "I found I could say things with color and shapes that I couldn't say any other way - things I had no words for" - Georgia O'Keefe I think the word is vagina
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Dark_Star
train driver pervading a desktop


Registered: 08/20/04
Posts: 31,859
Loc: Uranus
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: nuentoter] 1
#23593693 - 08/30/16 01:24 PM (7 years, 4 months ago) |
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Fuck the DEA. Completely useless & evil organization. Other LEO groups while enforcing unjust drug laws do go after real criminals as well. The DEA does not.
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LuSiD enthusiast
Stranger

Registered: 03/14/13
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: nuentoter]
#23593700 - 08/30/16 01:27 PM (7 years, 4 months ago) |
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Well i found a cheap ass vendor who if their product is quality, is going to see quite a few orders from me.(a drop in the bucket I'm sure compared to literally everyone using the stuff stocking up)
R/kratom is a fucking shitstorm right now.
I'm legitimately sick right now.
I guess this is the first step to making america great again right?
Next step:trump vs hillary
-------------------- I'm addicted to coke, weed, booze, ludes and speed. Not LSD, you can't get addicted to LSD, it was built by scientists. I ain't got no demons that gonna get woke. In erowid we trust. Just take your damn pills and don't ask any questions, you'll be fine.
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Konyap

Registered: 06/30/07
Posts: 33,945
Loc: Planet Piss
Last seen: 4 years, 2 months
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: Dark_Star]
#23593707 - 08/30/16 01:28 PM (7 years, 4 months ago) |
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high potential for abuse 15 deaths cause contaminants in the kratom
completely fabricated and bullshit lies
300 people a year die here from wait lets say it together "pharmaceuticals" and that's not even counting drugs that lower cholesteral or cause you to turn into a robot while kratom is sold on the free market and has done little to anyone besides constipation
Edited by Konyap (08/30/16 01:29 PM)
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musiclover420
psychonaut



Registered: 11/06/12
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: Konyap]
#23593728 - 08/30/16 01:36 PM (7 years, 4 months ago) |
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I think its time for a good old fashioned lynching....
Trevor Moore - Time For Guillotines
This song has never been so relevant...
-------------------- Don't worry about me, I've got all that I need. And I'm singing my song to the sky You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by I've got all and more, My smile, just as before. Is all that I carry with me I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free
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nooneman


Registered: 04/24/09
Posts: 14,564
Loc: Utah
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: ShroomDoom] 1
#23593770 - 08/30/16 01:45 PM (7 years, 4 months ago) |
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Game over for kratom in the US. Temporary scheduling is the kiss of death.
Don't worry too much though: I'm sure it'll still be available on DNM. Hell, there'll probably be huge DNM demand for it.
Also, fuck the DEA.
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LuSiD enthusiast
Stranger

Registered: 03/14/13
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: nooneman]
#23593789 - 08/30/16 01:50 PM (7 years, 4 months ago) |
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Quote:
nooneman said: Game over for kratom in the US. Temporary scheduling is the kiss of death.
Don't worry too much though: I'm sure it'll still be available on DNM. Hell, there'll probably be huge DNM demand for it.
Also, fuck the DEA.
Will they really risk mailing something so fucking bulky? Im curious as to what the weights are within the scheduling.
Is 1 g a felony amount? Or 10g?
-------------------- I'm addicted to coke, weed, booze, ludes and speed. Not LSD, you can't get addicted to LSD, it was built by scientists. I ain't got no demons that gonna get woke. In erowid we trust. Just take your damn pills and don't ask any questions, you'll be fine.
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Mr. Magic


Registered: 07/13/14
Posts: 1,951
Last seen: 1 year, 5 months
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: LuSiD enthusiast]
#23593825 - 08/30/16 01:58 PM (7 years, 4 months ago) |
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Ugh this is disgusting. I still have a kilogram but i might just order another kilo from my vendor.
:killme:
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nooneman


Registered: 04/24/09
Posts: 14,564
Loc: Utah
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: LuSiD enthusiast]
#23593826 - 08/30/16 01:58 PM (7 years, 4 months ago) |
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That's a good question. Like, what about states that have made all drug possession misdemeanors like California? If they're not specifically listed in California, then what's the penalty?
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musiclover420
psychonaut



Registered: 11/06/12
Posts: 19,563
Loc: PNW
Last seen: 2 years, 5 months
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: nooneman] 1
#23593836 - 08/30/16 02:01 PM (7 years, 4 months ago) |
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I just started a petition about this as I could not find one, feel free to take some time and make a better one to share but for now please sign this:
Stop kratoms scheduling sept 30th
Here is another one I just saw: Please do not make Kratom a Schedule I Substance
-------------------- Don't worry about me, I've got all that I need. And I'm singing my song to the sky You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by I've got all and more, My smile, just as before. Is all that I carry with me I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free
Edited by musiclover420 (08/30/16 02:05 PM)
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Celestial Traveler
Random Observer


Registered: 03/03/11
Posts: 7,639
Loc: Idaho
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Re: Forbes: DEA files for temporary scheduling of Kratom and It's bioactive components. [Re: ShroomDoom] 1
#23593915 - 08/30/16 02:30 PM (7 years, 4 months ago) |
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Why can't these bastards leave anything alone? What the fuck..
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