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OfflineCameron1996
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Registered: 11/28/15
Posts: 384
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Re: 5 OH DMT bufotenine and 4 OH DMT psilicin differences ? [Re: musiclover420]
    #22778418 - 01/14/16 01:24 PM (8 years, 2 months ago)

Could you possibly synthesize both of these compounds with hydroxylamine and dmt?

Or a peroxyacid reaction peroxide meOH folic acid and phosphoric acid on a ice bath and dmt?

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Offlinefamousgoodguy
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Registered: 11/06/15
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Re: DMT vs. Psilocin (4-HO-DMT) [Re: D2theP]
    #22778646 - 01/14/16 02:30 PM (8 years, 2 months ago)

Quote:

D2theP said:
nice link man, that's kinda strange how close they are. i do have to wonder if it had anything to do with evolution why dmt  and psilocin are similar.




It's called convergent evolution. They developed these mechanisms independently, fungi is a much older and ancient kingdom than plantae. (though this does not mean that psychoactive mushrooms are necessarily older than DMT producing plantae, but chances are they are, still unknown).

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OfflineCameron1996
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Re: DMT vs. Psilocin (4-HO-DMT) [Re: famousgoodguy]
    #22779764 - 01/14/16 07:33 PM (8 years, 2 months ago)

So mushrooms may be older than frogs and trees? I think it all happened when water happened but trees did probaly came last and frogs and mushrooms around the same time maybe along with mosquitios, worms, and other water based organisms

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OfflineCameron1996
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Registered: 11/28/15
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Re: DMT vs. Psilocin (4-HO-DMT) [Re: Cameron1996]
    #22779799 - 01/14/16 07:41 PM (8 years, 2 months ago)

Maybe fish and seedweed and lilys  and other aquatic life where here first because before there was land it was only water

Then the mushrooms, amphebians, bugs ,worms and grass after land started to form, i said mosquitos earlyer but i was wrong, there would of had to been creatures on land for thoes to live..i found a glitch in the matrix

then trees ,reptiles and land mammles

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Offlinemusiclover420
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Re: DMT vs. Psilocin (4-HO-DMT) [Re: Cameron1996]
    #22780006 - 01/14/16 08:33 PM (8 years, 2 months ago)

Quote:

Cameron1996 said:
So mushrooms may be older than frogs and trees? I think it all happened when water happened but trees did probaly came last and frogs and mushrooms around the same time maybe along with mosquitios, worms, and other water based organisms




They have found fossils of very ancient prehistoric fungi so they may predate most "modern" life forms by a long time :shrug:


--------------------
Don't worry about me, I've got all that I need. And I'm singing my song to the sky

You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by

I've got all and more, My smile, just as before. Is all that I carry with me

I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free


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OfflineMagicDave
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Registered: 08/06/15
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Re: DMT vs. Psilocin (4-HO-DMT) [Re: musiclover420]
    #22780287 - 01/14/16 09:33 PM (8 years, 2 months ago)

I thought in the tree of life way back that animals evolved from fungi. That is one reason that human genetics are closely related to fungi.

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OfflineSvetaketu
The Devil's Avocado 🥑
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Re: DMT vs. Psilocin (4-HO-DMT) [Re: MagicDave]
    #22780416 - 01/14/16 10:06 PM (8 years, 2 months ago)

I can't recall exactly who everyones common ancestors were, but giant mushrooms were among the first organisms on land, and they were huge back then! They have found fossils of fungi 24 feet tall and 3 feet wide :yesnod:

http://www.smithsonianmag.com/ist/?next=/smart-news/long-before-trees-overtook-the-land-earth-was-covered-by-giant-mushrooms-13709647/


--------------------
LAGM2020
LAGM2021

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OfflineMagicDave
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Re: DMT vs. Psilocin (4-HO-DMT) [Re: Svetaketu]
    #22780439 - 01/14/16 10:14 PM (8 years, 2 months ago)

Quote:

Svetaketu said:
I can't recall exactly who everyones common ancestors were, but giant mushrooms were among the first organisms on land, and they were huge back then! They have found fossils of fungi 24 feet tall and 3 feet wide :yesnod:

http://www.smithsonianmag.com/ist/?next=/smart-news/long-before-trees-overtook-the-land-earth-was-covered-by-giant-mushrooms-13709647/




Could you imagine harvesting a 24 foot psychedelic mushroom. One mushroom would probably be a couple hundred dry grams. :mushroom2:

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OfflineComaDivine
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Re: 5 OH DMT bufotenine and 4 OH DMT psilicin differences ? [Re: Cameron1996]
    #22780504 - 01/14/16 10:32 PM (8 years, 2 months ago)

Quote:

Cameron1996 said:
I was wondering the differences in synthesis of 5 OH DMT bufotenine the stuff on colorado river toad backs and 4 OH DMT psilocin. If one where to make psilocin how would they make sure the OH was in the right place to make psilocin instead of 5 HO dmt



The reason why mushrooms oxidize at the 4 position while toads oxidize at the 5 position is that the two reactions are catalyzed by different enzymes. In a living organism, enzymes are the proteins that act as catalysts to increase the rate (speed) of chemical reactions, and they will determine which products are formed (this is transition state chemistry...!)

EDIT: and yes this has A LOT to do with evolution. Enzymes are the products of evolution since they are always encoded by at least one gene and their activity can be subject to many types of gene regulation. One can track the progress of evolution biochemically through the comparative analysis of enzymes.


--------------------
:sun:

Edited by ComaDivine (01/14/16 10:34 PM)

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OfflineCameron1996
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Registered: 11/28/15
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Re: 5 OH DMT bufotenine and 4 OH DMT psilicin differences ? [Re: ComaDivine]
    #22780604 - 01/14/16 11:00 PM (8 years, 2 months ago)

Holy damn you just described why it happens, i would of never found that in a million years thanks comadivine

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Offlinemusiclover420
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Re: 5 OH DMT bufotenine and 4 OH DMT psilicin differences ? [Re: ComaDivine] * 1
    #22780624 - 01/14/16 11:05 PM (8 years, 2 months ago)

:havesomescience:


--------------------
Don't worry about me, I've got all that I need. And I'm singing my song to the sky

You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by

I've got all and more, My smile, just as before. Is all that I carry with me

I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free


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OfflineComaDivine
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Registered: 11/24/09
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Loc: USA
Last seen: 7 years, 9 months
Re: 5 OH DMT bufotenine and 4 OH DMT psilicin differences ? [Re: musiclover420]
    #22781463 - 01/15/16 08:30 AM (8 years, 2 months ago)

Quote:

Cameron1996 said:
Holy damn you just described why it happens, i would of never found that in a million years thanks comadivine



Quote:

musiclover420 said:
:havesomescience:




:abbie::pipesmoke::cookiemonster:


--------------------
:sun:

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OfflineMagicDave
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Re: 5 OH DMT bufotenine and 4 OH DMT psilicin differences ? [Re: ComaDivine]
    #22781576 - 01/15/16 09:31 AM (8 years, 2 months ago)

DMT came from the grays and psilocin came from fairies.

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