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shezzac123
Stranger

Registered: 10/21/15
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Last seen: 8 years, 3 months
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psilocin extracion using isopropnal
#22414802 - 10/21/15 05:52 PM (8 years, 3 months ago) |
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bit of a newbie any advice isopropanol i believe is a good alcohol for this any posts out there that can help get me through this cheers
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shezzac123
Stranger

Registered: 10/21/15
Posts: 3
Last seen: 8 years, 3 months
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Re: psilocin extracion using isopropnal [Re: shezzac123]
#22414818 - 10/21/15 05:56 PM (8 years, 3 months ago) |
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Quote:
shezzac123 said: bit of a newbie any advice isopropanol i believe is a good alcohol for this any posts out there that can help get me through this cheers
i should say that ive dried the tissue blended it up added the alcohol and filtered it am left with a green liquid am a bit lost of at this point any one piont me in the right direction
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shezzac123
Stranger

Registered: 10/21/15
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Re: psilocin extracion using isopropnal [Re: shezzac123]
#22416677 - 10/22/15 04:13 AM (8 years, 3 months ago) |
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has anyone tried this ? ived read loads on the subject but reading and doing are 2 different things could do with some pointers to avoid disappointment
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micro
bunbun has a gungun



Registered: 05/09/03
Posts: 7,532
Loc: Brick City
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Re: psilocin extracion using isopropnal [Re: shezzac123]
#22417775 - 10/22/15 11:30 AM (8 years, 3 months ago) |
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yeah
methanol works best though I'd be surprised if you could tell
they should both bring out the alkaloids alright
since a lot of -ybin may dephosphorylate to -cin due to enzymes you want to be fast and dry (use no extra water anyway) but not so much to hurt the procedure. i'd probably give it at the very least, a few days (3, maybe?) just to let it sit through various alcohol pulls. someone mentioned freezing it
also, keep in mind you won't get the crystallized form. someone on here who goes by WillSolvem I think did; I think he was doing alcohol than A/B and probably used tartaric acid
i had never tried that
-------------------- Any research paper or book for free (Avatar is Maxxy, a character by Mizzyam, RIP)
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micro
bunbun has a gungun



Registered: 05/09/03
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Re: psilocin extracion using isopropnal [Re: micro]
#22418031 - 10/22/15 12:18 PM (8 years, 3 months ago) |
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oh and hint, you can dry the alcohol with a desiccant generally found in that same isle/department
70/90 are best for an antiseptic, not really in this case however
-------------------- Any research paper or book for free (Avatar is Maxxy, a character by Mizzyam, RIP)
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champinhom
Lord Justhappensness


Registered: 03/06/09
Posts: 987
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Re: psilocin extracion using isopropnal [Re: shezzac123]
#22429447 - 10/24/15 09:03 PM (8 years, 3 months ago) |
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isopropyl alki is poison. You should use ethyl alki for extractionary purposes. That way, you can preserve your extraction and not have to apply a process of total evaporation to your results. It takes a fairly long time to evap all that bad alki.
Also, it has been found that the best extraction is made with a mixture of alcohol and water--the ratio is 70/30. Alcohol alone is not a good psilocybin solvent. It is, however, a wonderful agent of preservation.
-------------------- My father used to say: I don't care what else you do in life, just don't be an asshole. People, forgive me when I forget what my daddy said. Cut back the proliferating list of people whose opinions can hurt you. Unless they have done or want to do you some good, their views are just not worth tracking. Saul Bellow “People are just cannibals unless they leave each other alone.” Doris Lessing Those whom the gods would save, they dower with compassion. Mr. P. Silocybin
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micro
bunbun has a gungun



Registered: 05/09/03
Posts: 7,532
Loc: Brick City
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Re: psilocin extracion using isopropnal [Re: champinhom]
#22433649 - 10/25/15 08:32 PM (8 years, 3 months ago) |
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1.) There is no such thing as isopropyl alki or ethyl alki. or alki for that matter (it is an alcohol)
2.) What you are saying bears no relevance since a) you should let the alcohol evaporate anyway; there will be none left this is not a problem assuming it evaporates clear (i.e. Walgreens' stuff) and b) any ethyl alcohol you buy at the store will have poisonous stuff in it as well (hence the term denatured)
3.) While I'd tend to agree with you, it would be for the wrong reasons. It is not because alcohol 'is not a good psilocybin solvent.' If aything, you're referring to that Gartz paper where he stated it is better for denaturing enzymes (i.e. phophatases) so it may better preserve the alkaloids. Alcohol is a better solvent for psilocybin but acidic water would work as well, since the somewhat-basic amine group is protonated and gains a net charge, making it more polar.
-- micro
-------------------- Any research paper or book for free (Avatar is Maxxy, a character by Mizzyam, RIP)
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Trippysubstance
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Re: psilocin extracion using isopropnal [Re: micro]
#22473168 - 11/03/15 08:22 PM (8 years, 2 months ago) |
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Interesting
Edited by Trippysubstance (11/07/15 10:48 PM)
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bodhisatta 
Smurf real estate agent


Registered: 04/30/13
Posts: 61,889
Loc: Milky way
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Pull with hot acidulated water. 170f water will deactivate all the enzymes that would degrade actives. Water is the best solvent add ethanol back in if you think it helps as a preservative.
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DrCrumbs
Alpha Blue


Registered: 10/25/11
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Re: psilocin extracion using isopropnal [Re: bodhisatta]
#22475034 - 11/04/15 08:52 AM (8 years, 2 months ago) |
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I've done this a ton of times with 91% iso. I was trying to find a way to determine potency of APE vs. B+. Problem was pointed out to me that it also extracts the sugars so its not reliable for comparisons. It is amazing for extraction though.
I would grind up a few grams of mushrooms, place them in a coffee filter. Let this soak in a shot of iso 91% for about ten min.'s more time didnt seem to matter.
Remove and squeeze (I would often double wrap the filters as they are kind of weak).
I had a very large spoon that I would poor it into. Then I would add flameless heat to it. It doesnt take long to evape all the iso out. You can use a hot water bath, etc.
Your left with a golden ball that smells super potent. Its sugars, salts and magic.
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drake89
Mushroom Magnate



Registered: 06/26/11
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Re: psilocin extracion using isopropnal [Re: DrCrumbs]
#22476485 - 11/04/15 12:59 PM (8 years, 2 months ago) |
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Quote:
DrCrumbs said: I've done this a ton of times with 91% iso. I was trying to find a way to determine potency of APE vs. B+. Problem was pointed out to me that it also extracts the sugars so its not reliable for comparisons. It is amazing for extraction though.
I would grind up a few grams of mushrooms, place them in a coffee filter. Let this soak in a shot of iso 91% for about ten min.'s more time didnt seem to matter.
Remove and squeeze (I would often double wrap the filters as they are kind of weak).
I had a very large spoon that I would poor it into. Then I would add flameless heat to it. It doesnt take long to evape all the iso out. You can use a hot water bath, etc.
Your left with a golden ball that smells super potent. Its sugars, salts and magic.
is ethanol any different?
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Handslikehouses
Lion Skin

Registered: 09/26/15
Posts: 201
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Re: psilocin extracion using isopropnal [Re: drake89]
#22477236 - 11/04/15 04:23 PM (8 years, 2 months ago) |
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I know this is going to sound dumb, I'm completely new to this, I've never even heard of extracting it, but what do you do with it once it's extracted? Eat it like normal?
-------------------- Considering spores can survive the vacuum of space, I would assume it's safe to say that mushrooms are on every planet waiting for the right conditions to present themselves. What it all boils down to, is aliens are on shrooms.

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micro
bunbun has a gungun



Registered: 05/09/03
Posts: 7,532
Loc: Brick City
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Quote:
bodhisatta said: Pull with hot acidulated water. 170f water will deactivate all the enzymes that would degrade actives. Water is the best solvent add ethanol back in if you think it helps as a preservative.
It was shown that methanol was the best solvent all-around, but you are right in that acidified water is better at pulling psilocybin but not psilocin (for references, see Wurst 1992 and Gartz 1987).
Quote:
DrCrumbs said: I've done this a ton of times with 91% iso. I was trying to find a way to determine potency of APE vs. B+. Problem was pointed out to me that it also extracts the sugars so its not reliable for comparisons. It is amazing for extraction though.
It will pull a great deal of things; anything in the mushroom that is alcohol soluble.
For more fine-grained extraction use an acid-base extraction after the alcohol one.
That will only pull alkaloids.
Quote:
drake89 said: is ethanol any different?
Than methanol? Not a great deal, slightly less polar due to a longer hydrocarbon chain.
You can drink ethanol but since it is being used as a solvent that is evaporated that isn't really applicable.
Quote:
Handslikehouses said: I know this is going to sound dumb, I'm completely new to this, I've never even heard of extracting it, but what do you do with it once it's extracted? Eat it like normal?
That or put it into gel caps. I haven't heard of people doing nuttier things like trying to snort or smoke it. I'm surprised I never tried that myself
-------------------- Any research paper or book for free (Avatar is Maxxy, a character by Mizzyam, RIP)
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Handslikehouses
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Re: psilocin extracion using isopropnal [Re: micro]
#22479337 - 11/05/15 02:56 AM (8 years, 2 months ago) |
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lol thanks man
-------------------- Considering spores can survive the vacuum of space, I would assume it's safe to say that mushrooms are on every planet waiting for the right conditions to present themselves. What it all boils down to, is aliens are on shrooms.

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WillSolvem
Odd-Hand




Registered: 04/24/12
Posts: 1,519
Loc: Chapter 26
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--------------------
AMU Q&A Thread because questions deserve answers.
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QBdoobie
Funkadelic


Registered: 11/08/15
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Re: psilocin extracion using isopropnal [Re: WillSolvem]
#22506763 - 11/10/15 07:45 PM (8 years, 2 months ago) |
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Very interesting
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DrCrumbs
Alpha Blue


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Re: psilocin extracion using isopropnal [Re: QBdoobie]
#22533071 - 11/16/15 03:01 PM (8 years, 2 months ago) |
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ethanol is nice if you can get a high enough proof. In MD I was able to 95% grain alcohol it rocked.
Also if you lower the temperature of the solvent you can prevent pulling unwanted stuff (like sugars and salts).
This might not be practical as you may need a -85F column. Tell me more about precipitating with acid/base's.
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