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Rebelutionsssss
Mdmazing



Registered: 07/23/14
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Loc: San Francisco
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This shits retarded
#22357469 - 10/10/15 02:18 AM (8 years, 3 months ago) |
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My friends called me stupid for thinking that a generic drug with the same amount of actives as the brand name are the same. Everyone thought I was stupid even though I explained it pisses me off
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Amanita86
OTD Keymaster


Registered: 09/26/12
Posts: 89,464
Loc: hades
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Generics have a little more leeway in terms of the ingredient's measurements. Brand name has to "be", generics just 'represent' the brand name recipe.
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Orange clock, pencil "They threw me off the hay truck about noon..."
*Mark 15:34  Gam zeh ya’avor...
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Burke Dennings
baby merchant

Registered: 11/29/04
Posts: 81,641
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Re: This shits retarded [Re: Amanita86]
#22357495 - 10/10/15 02:46 AM (8 years, 3 months ago) |
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I've really looked into this myth, and don't get what people are saying. My whole "drug career" I've heard people say that the generic can have +/- 20% of the active medication. The FDA claims in no uncertain terms that that is NOT the case. I've read an article published by them that addresses this legend, and it states that if the brand name makes a med that is, say, 100mg, the generic must also be exactly 100mg, not anywhere from 80-120mg. Over the years here I've asked so many people to link to a reputable & scholarly article that says generics are allowed to do that, no one can find one. And if you think about it for a moment, it doesn't make sense that this would be the case.
Unless I'm misreading what you guys are talking about. The OP is a bit vague, but it seems to me that he has it right.
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The Moose
Alces alces


Registered: 08/31/15
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Yea I feel like there is no way something as regulated and prescription drugs could vary in a degree that much.
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Burke Dennings
baby merchant

Registered: 11/29/04
Posts: 81,641
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Re: This shits retarded [Re: The Moose]
#22357509 - 10/10/15 02:52 AM (8 years, 3 months ago) |
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It's one of those drug myths that everyone repeats as fact without looking into it, and it's absurd.
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The Moose
Alces alces


Registered: 08/31/15
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Yea I used to be really into pills and there's just no way. IME generics are the same as name-brand pharms. Its funny how shit like that gets around though
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Amanita86
OTD Keymaster


Registered: 09/26/12
Posts: 89,464
Loc: hades
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Links?
I was never heavy into pills, it's something I heard covered on NPR. Crystal G (I know) got into a debate about it and linked up a few things that seem to have stuck in my memory as 'trustworthy' sources... I think it was a thread from years ago, I may have been looking up a dead guy and found that whole convo..
It's one of those things where I guess I haven't personally felt the need to iron it out much further than I have so far since I'm not real big on pills.
What article that you found irons it out?
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Orange clock, pencil "They threw me off the hay truck about noon..."
*Mark 15:34  Gam zeh ya’avor...
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SunnyD
WiZarD oF LoVe



Registered: 04/29/13
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Quote:
Rebelutionsssss said: My friends called me stupid for thinking that a generic drug with the same amount of actives as the brand name are the same. Everyone thought I was stupid even though I explained it pisses me off
your friends sound stupid
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        And to everyone who thinks life is just a game, Do you like the part you are playing? This is the time in life I am living! And I face each day with a smile My music Library of Synthesizer goodness
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The Moose
Alces alces


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Re: This shits retarded [Re: Amanita86] 1
#22357535 - 10/10/15 03:07 AM (8 years, 3 months ago) |
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I would find it hard to believe there are pharms out there that vary in dose by as much as 20%
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Gorlax



Registered: 05/06/08
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Re: This shits retarded [Re: The Moose]
#22357541 - 10/10/15 03:10 AM (8 years, 3 months ago) |
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Absolutely false. 20% is an insane amount of variation for anything. They don't build bridges that have 20% chance of collapsing so they aren't making pharms that are 20% weaker/stronger.
I've studied this law for investing and generics are equivalents with the slightest variation in potency so much so is negligent.
People are stupid. There is no point in trying to convince anyone.
I still know people who don't believe pressed xanax exists when they have yellow bar imprints on green bars.
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Burke Dennings
baby merchant

Registered: 11/29/04
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Re: This shits retarded [Re: Amanita86]
#22357554 - 10/10/15 03:15 AM (8 years, 3 months ago) |
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This isn't the in depth article I once found, but it's a fact sheet with the basics.
hxxp://www.fda.gov/Drugs/ResourcesForYou/Consumers/BuyingUsingMedicineSafely/UnderstandingGenericDrugs/ucm167991.htm
(To utilize the link, replace the x's in "hxxp" with t's. I didnt want to directly link from boomtown to a govt site, so I "broke" the link.)
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Burke Dennings
baby merchant

Registered: 11/29/04
Posts: 81,641
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Re: This shits retarded [Re: Gorlax]
#22357557 - 10/10/15 03:18 AM (8 years, 3 months ago) |
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For whatever reason, whenever there is a number on the variance when I hear this myth repeated, it's always 20%. I wonder where this got started. Probably someone trying to sell their brand name meds on the black market for more than the generics.
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The Moose
Alces alces


Registered: 08/31/15
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I don't see why linking matters?
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Amanita86
OTD Keymaster


Registered: 09/26/12
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Loc: hades
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Well, there you go. I guess that clarifies that one. I wonder where the other side of the argument originates from..
Quote:
Burke Dennings said: Probably someone trying to sell their brand name meds on the black market for more than the generics.

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Orange clock, pencil "They threw me off the hay truck about noon..."
*Mark 15:34  Gam zeh ya’avor...
Edited by Amanita86 (10/10/15 03:39 AM)
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makaveli8x8
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Re: This shits retarded [Re: The Moose]
#22357581 - 10/10/15 03:39 AM (8 years, 3 months ago) |
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don't the pills come in a box, and the box tells you on the back exactly the percent of each chemical in it?
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The Moose
Alces alces


Registered: 08/31/15
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I mean when I've had pills I get them in a bottle lol
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The Moose
Alces alces


Registered: 08/31/15
Posts: 2,389
Last seen: 1 year, 10 months
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Re: This shits retarded [Re: The Moose]
#22357584 - 10/10/15 03:41 AM (8 years, 3 months ago) |
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But it tells me dosage per pill, typically in MG or MCG.
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Gorlax



Registered: 05/06/08
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Re: This shits retarded [Re: The Moose]
#22357610 - 10/10/15 04:02 AM (8 years, 3 months ago) |
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I know where people come from when they say brand does matter. I never understood it to be a difference in actual milligram amount but rather absorption or cleaner chemical. I know the old blue watson 540 vicodins blew the yellow ones out of the water. Also I think yellow xanax bars are the gold standard for xanax compared to most others.
Xanax bars are literally the worst right now. Black market people are making bars that are 3mg, 3.5mg, and 4mg for reasons idk. They are labeled as 2mg and these are mixed up in the real ones so variation to variation with street bought xanax has always been a problem.
Pharm drugs I never questioned. No reason to.
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The Moose
Alces alces


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Re: This shits retarded [Re: Gorlax]
#22357619 - 10/10/15 04:08 AM (8 years, 3 months ago) |
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I mean IME (vikes were on my list of DOCs) a vike is a vike, ya know? I've had the watsons and the m360 and probably 2-3 other varieties of press and never been notable of a difference. Honestly I've taken 3-4 year post expired vikes and its been the same
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abltsandwich
JFK = Jelly Donut




Registered: 06/16/09
Posts: 11,537
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Re: This shits retarded [Re: The Moose]
#22357638 - 10/10/15 04:17 AM (8 years, 3 months ago) |
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FDA regulation wouldn't allow drugs that people with disorders that count on accurate dosage to exist on the market. They claim the exact same standards for generics as name brands. Now is the FDA trustworthy? That's a different question.
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