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InvisibleMostly_HarmlessM
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Intellectually disabled often get antipsychotics in absence of mental illness [UK]
    #22181669 - 09/03/15 03:52 AM (8 years, 4 months ago)

http://www.nature.com/news/intellectually-disabled-often-get-antipsychotics-in-absence-of-mental-illness-1.18281

Quote:

UK study confirms widespread use of drugs to control disruptive and aggressive behaviour.

01 September 2015



A survey of UK health records found widespread use of antipsychotic drugs in intellectually disabled people.

Antipsychotic drugs are widely used to blunt aggressive behaviour in people with intellectual disabilities who have no history of mental illness, a UK survey of medical records finds, even though the medicines may not have a calming effect. The finding is worrisome because antipsychotic drugs can cause severe side effects such as obesity or diabetes.

Psychiatry researcher Rory Sheehan and colleagues1 at University College London studied data from 33,016 people with intellectual disabilities from general-care practices in the United Kingdom over a period of up to 15 years. The researchers found that 71% of 9,135 people who were treated with antipsychotics had never been diagnosed with a severe mental illness, and that the drugs were more likely to be prescribed to those who displayed problematic behaviours.

“We suspected that this would be the case, but we didn’t know the true extent,” Sheehan says.

“We should be worried because the rates are high,” says James Harris, a psychiatrist at Johns Hopkins University in Baltimore, Maryland. But he adds that it is hard to determine whether treatment with antipsychotics is appropriate without knowing what other forms of treatment were available to people in the study. It is possible that medication was the only option available or that it was used to dampen a person's behaviour enough that they could participate in therapy or other types of treatment.

Placebo effect

Evidence suggests that the drugs are not effective at treating aggressive and disruptive behaviour, says psychiatrist Peter Tyrer of Imperial College London. In 2008, he and several colleagues gave haloperidol (Haldol), risperidone (Risperdal) or a placebo to people who had intellectual disabilities but no mental illness, and exhibited aggressive behaviour. The drugs were no better at reducing behavioural problems than the placebo2. Because the placebo reduced aggressive behaviour by 79%, Tyrer notes, it may be that antipsychotics are so prevalent simply because they seem to have an effect and can be administered by untrained caregivers in an emergency. “It’s impossible to do a psychological intervention at two in the morning,” Tyrer says. 

The popularity of antipsychotics could also be related to their marketing. In 2013, global health-care company Johnson & Johnson paid more than US$2.2 billion to settle a lawsuit charging that it had improperly marketed risperidone, which had been approved for use in schizophrenia, to treat behaviour problems in children, adults with mental disabilities and elderly people with dementia.

References

    Sheehan, R., et al. BMJ 351 http://dx.doi.org/10.1136/bmj.h4326 (2015).

    Tyrer, P. et al. Lancet 371, 57–63 (2008).





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InvisibleShiithead
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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Mostly_Harmless] * 1
    #22181694 - 09/03/15 04:35 AM (8 years, 4 months ago)

Interestingly enough, people with massive intellect and no direction are often subjected scrutiny and anti-psychotics.


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Invisiblenice1returns
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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Mostly_Harmless]
    #22181981 - 09/03/15 08:05 AM (8 years, 4 months ago)

Fuckers put me on this when I don't have an illness,
hand it like candy

Pharma monopoly and trigger happy docs
:crankey:


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OfflineKonyap

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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: nice1returns]
    #22182348 - 09/03/15 10:14 AM (8 years, 4 months ago)

I took risperdone for schizophrenia and it made my therapist think I was autistic :lol:

those drugs are really bad
I don't know what use they have other then calming people who are extremely politically correct


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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Konyap] * 1
    #22182458 - 09/03/15 10:45 AM (8 years, 4 months ago)

When you don't feel like dealing with people, give them a seroquel to shut them up.  2015 Mental Health 101


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OfflineKonyap

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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Cognitive_Shift]
    #22182605 - 09/03/15 11:27 AM (8 years, 4 months ago)

Stupid fucks are so up their own ass they don't even "think" schizophrenia is a symptom of dementia which is an aged over wired brain..


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Offlinemorbiddoctor
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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Konyap]
    #22183106 - 09/03/15 01:25 PM (8 years, 4 months ago)

Zyprexa for a year made me gain 40 pounds and have no will of my own. Being a zombie sucks. Fuck these shady/ignorant docs. I'm glad this made the news.


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OfflineTNK
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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Konyap]
    #22184246 - 09/03/15 06:35 PM (8 years, 4 months ago)

Quote:

Konyap said:
I took risperdone for schizophrenia and it made my therapist think I was autistic :lol:

those drugs are really bad
I don't know what use they have other then calming people who are extremely politically correct




Same, I was going through a rough time in life and they threw resperdial(resperdone) at me like candy.

It did not help the situation, in fact it made it about x10 as worse as before.


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Edited by TNK (02/22/22 22:22 PM)


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OfflineKonyap

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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: TNK]
    #22184725 - 09/03/15 08:03 PM (8 years, 4 months ago)

I just didn't like being force fed drugs

My symptoms usually fuck off after a few months for the most part


Edited by Konyap (09/05/15 09:29 PM)


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InvisibleCognitive_Shift
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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Konyap]
    #22184785 - 09/03/15 08:13 PM (8 years, 4 months ago)

All those anti-psychotics are dopamine antagonists for the most part.  I've only taken seroquel recreationally for sleep... I can't imagine how someone would be expected to take that stuff during the day time.


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OfflineKonyap

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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Cognitive_Shift]
    #22184816 - 09/03/15 08:20 PM (8 years, 4 months ago)

http://www.canhr.org/stop-drugging/archives/1193

Risperdal More than Doubles Risk of Adverse Events for People with Dementia. Therefore, Keep People with Dementia on Risperdal. Wait . . . what?


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OfflinePurpleHaze147
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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Cognitive_Shift]
    #22194056 - 09/05/15 07:01 PM (8 years, 4 months ago)

Quote:

Cognitive_Shift said:
All those anti-psychotics are dopamine antagonists for the most part.  I've only taken seroquel recreationally for sleep... I can't imagine how someone would be expected to take that stuff during the day time.



+1

I take it to sleep too occasionally and I'm tellin you that's the most sedating drug I've ever tried (at theraputic dosages and I have pretty much tried every drug known to man lol). I can't imagine how you'd be able to function properly on that shit. All anti-psychotics are extremely sedating.


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OfflineKonyap

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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: PurpleHaze147]
    #22194080 - 09/05/15 07:09 PM (8 years, 4 months ago)

I can't imagine being on any drug to sleep is good for you


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OfflinePurpleHaze147
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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Konyap]
    #22194773 - 09/05/15 09:51 PM (8 years, 4 months ago)

^ when I said I can't imagine being able to function on it properly I meant that people with mental disorders are told to take it during the day. I'd pass the fuck out if I took seroquel during the day.


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OfflineKonyap

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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: PurpleHaze147] * 1
    #22194896 - 09/05/15 10:27 PM (8 years, 4 months ago)

They're real asshole's about it, like you don't have any rights you have to take it when they offer it like you're being fed castor oil or something.

It might be appropriate for someone who wants to take naps but is never tired:lol:


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Offlinecircastes
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Re: Intellectually disabled often get antipsychotics in absence of mental illness [UK] [Re: Konyap]
    #22203152 - 09/07/15 05:06 PM (8 years, 4 months ago)

Risperdal and Seroquel are definitely sedating, but there are some non-sedating ones. These drugs are useless except for moderately reducing the symptoms of rampant, runaway schizophrenia. If you have mild schizophrenia you shouldn't be on them. An exception is clozapine which targets lack of pleasure, amotivation and overly concrete thinking by agonising the serotonin 1A receptor and this is all present even in mild schizophrenia.

All atypical antipsychotics have been shown to reduce brain volume linearly with use. It is unknown whether the 'atypical atypicals', like Abilify, which ACTIVATE dopamine receptors, do the same. Avoid them unless you're truly fucked or if you're completely sick of your situation.


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