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Offlineinked4life
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question on the ability to enhance potency, try to follow me here
    #22121842 - 08/21/15 11:09 AM (8 years, 5 months ago)

so i was wondering if i could in a sense change the potency of the flushes by doing the following : spent cakes or previous dried batch of mushies ground up and soaked in everclear to extract psilo and filtered and poured onto cookie sheet to slowly evaporate alcohol, scrape up the crystals and put a measures amount into a batch of brf recipe, since the pc only reachs a temp that isnt combustable , that even if the crystals disolved into the substrate that the levels of psilo would be much higher than average cakes, there fore producing a myceluim network that would produce more potent fruits. do you believe that this could be achievable.


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Invisiblejbaby007
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Re: question on the ability to enhance potency, try to follow me here [Re: inked4life]
    #22121928 - 08/21/15 11:18 AM (8 years, 5 months ago)

No. Potency is based on genetics. If you want more potent fruits you'll have to clone and isolate a potent fruit then grow it out and do a taste test. Or try a different variety.


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OfflinePsilosopherr
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Re: question on the ability to enhance potency, try to follow me here [Re: jbaby007]
    #22122045 - 08/21/15 11:35 AM (8 years, 5 months ago)

:lol: I like this idea a lot, though I am skeptical.

This is definitely not advanced mycology though.


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InvisiblebodhisattaMDiscordReddit
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Re: question on the ability to enhance potency, try to follow me here [Re: Psilosopherr]
    #22124448 - 08/21/15 08:51 PM (8 years, 5 months ago)

everclear sucks for extracting psilocin and psilocybin. you want to use water. water is the best solvent for the actives.

you won't get crystals if you evaporate, you'll get inactive salts. if you even got crystals of pure psilocin and psilocybin they would quickly degrade as pure samples anyway.

fungi would just break down the molecules and re build them, it won't boost potency.

some of the most potent species grow naturally on the lowest nutrition substrates.


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OfflinePsilosopherr
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Re: question on the ability to enhance potency, try to follow me here [Re: bodhisatta]
    #22124564 - 08/21/15 09:18 PM (8 years, 5 months ago)

Quote:

bodhisatta said:
everclear sucks for extracting psilocin and psilocybin. you want to use water. water is the best solvent for the actives.

you won't get crystals if you evaporate, you'll get inactive salts. if you even got crystals of pure psilocin and psilocybin they would quickly degrade as pure samples anyway.

fungi would just break down the molecules and re build them, it won't boost potency.

some of the most potent species grow naturally on the lowest nutrition substrates.



interesting

I can 2nd his recommendation of water over alcohol for extraction. psilocybin is soluble in everclear, but not very.


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Invisiblejbaby007
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Re: question on the ability to enhance potency, try to follow me here [Re: Psilosopherr]
    #22124766 - 08/21/15 10:07 PM (8 years, 5 months ago)

Well I'm just gonna stop commenting :rofl:


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Invisible36fuckin5
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Re: question on the ability to enhance potency, try to follow me here [Re: Psilosopherr]
    #22125056 - 08/21/15 11:32 PM (8 years, 5 months ago)

Quote:

rbalzer said:
Quote:

bodhisatta said:
everclear sucks for extracting psilocin and psilocybin. you want to use water. water is the best solvent for the actives.

you won't get crystals if you evaporate, you'll get inactive salts. if you even got crystals of pure psilocin and psilocybin they would quickly degrade as pure samples anyway.

fungi would just break down the molecules and re build them, it won't boost potency.

some of the most potent species grow naturally on the lowest nutrition substrates.



interesting

I can 2nd his recommendation of water over alcohol for extraction. psilocybin is soluble in everclear, but not very.




Actually, 100 proof or less vodka would be best. Aqueous methanol is really best, but that's toxic and since you can't crystallize without serious, expensive equipment vodka is your best best.

I wanna say it was David Nichols that published psilocybin and psilocin solubility data oh so long ago. There's a chart floating around somewhere that I can't find right now.

Not to say water can't work, especially acidic water, and I'm not saying you'll lose more than a few micrograms that you'll never notice, but the numbers say aqueous ethanol or methanol work best for psilocin and psilocybin respectively.


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Redd Foxx said:
If you're offended I don't give a shit and don't come see me no more.

Pat The Bunny said:
A punk rock song won't ever change the world, but I can tell you about a couple that changed me.

bodhisatta said:
i recommend common sense and figuring it out.

These are the TEKs I use. They're all as cheap and easy as possible, just like your mom.


Edited by 36fuckin5 (08/21/15 11:37 PM)


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OfflinePsilosopherr
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Re: question on the ability to enhance potency, try to follow me here [Re: 36fuckin5]
    #22125091 - 08/21/15 11:43 PM (8 years, 5 months ago)



This is the only chart I've seen on the subject. Notice the differences between psilocin and psilocybin. I believe psilocybin is the main one you'd be after in extraction, and according to that chart water is best. :shrug:

I don't really know where this chart comes from though. koods just posted it in a thread I posted a while back.


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InvisiblebodhisattaMDiscordReddit
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Re: question on the ability to enhance potency, try to follow me here [Re: Psilosopherr]
    #22125670 - 08/22/15 06:40 AM (8 years, 5 months ago)

100 proof vodka works because of the water. The alcohol is unnecessary unless you think its going to help preserve your extraction. Either way hands down best extraction

Boiling water, powdered cubes. Then freeze your tea if you want to save it


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OfflinePsilosopherr
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Re: question on the ability to enhance potency, try to follow me here [Re: bodhisatta]
    #22126247 - 08/22/15 10:22 AM (8 years, 5 months ago)

Quote:

bodhisatta said:
100 proof vodka works because of the water. The alcohol is unnecessary unless you think its going to help preserve your extraction. Either way hands down best extraction

Boiling water, powdered cubes. Then freeze your tea if you want to save it



Funny when people think everclear works well buts its only the small percentage of water in there doing the work :lol:

either freeze or mix with alcohol afterward. Don't know which is better but either will extend the shelf life


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Offlinemackrel
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Re: question on the ability to enhance potency, try to follow me here [Re: inked4life]
    #22127877 - 08/22/15 04:52 PM (8 years, 5 months ago)

Let me try to answer your question since this thread has moved towards psilo-extraction techniques and away from potency increases.

The best way to supposedly increase yields are outlined in this paper. Basically, they just added tryptamine derivatives to the substrate which are subsequently converted by the mushroom into psilocin. Fool around with tryptamine's in the substrate and see what happens (and document it on here for our edification!), otherwise your psilocin/cybin will not likely survive the sterilization and subsequent spawn run in the substrate without degrading from oxygen or heat or metabolites.


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Invisible36fuckin5
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Re: question on the ability to enhance potency, try to follow me here [Re: mackrel]
    #22129071 - 08/22/15 11:06 PM (8 years, 5 months ago)

If you can't run chromatography, adding shit to your sub won't be able to be quantified.

Every person who has tried this can't tell a difference. It's basically bunk. If any more alkaloids ARE produced, they're in minute quantities.


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Redd Foxx said:
If you're offended I don't give a shit and don't come see me no more.

Pat The Bunny said:
A punk rock song won't ever change the world, but I can tell you about a couple that changed me.

bodhisatta said:
i recommend common sense and figuring it out.

These are the TEKs I use. They're all as cheap and easy as possible, just like your mom.


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Offlinemackrel
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Re: question on the ability to enhance potency, try to follow me here [Re: 36fuckin5]
    #22132383 - 08/23/15 06:51 PM (8 years, 5 months ago)

You could just perform a simple psilo- extraction from dry materials (as referenced previously) instead of having to waste time running GC to test for potency increases... several replicates of extractions on controls and treated substrates should give you an idea if there is any significant increase.

Really the best solution is to grow cyans or azurs on a rich and very complex substrate. They are considered the most potent and creating a diverse/complex substrate works best for yield/potency increases.


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Invisible36fuckin5
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Re: question on the ability to enhance potency, try to follow me here [Re: mackrel]
    #22132456 - 08/23/15 07:08 PM (8 years, 5 months ago)

But a simple extraction is sure to be contaminated with crap from the plant material that you don't want. This makes measuring milligrams impossible.

You need liquid chromatography to separate your alkaloids without destroying them, then you can weigh them.

An eighth of Cubensis has something like 10 mg of psilocybin, give or take a few mg. If you're a mg off because of fats or lipids in your extract that makes a giant difference. That's a 10% increase that might not really be there.


--------------------
Redd Foxx said:
If you're offended I don't give a shit and don't come see me no more.

Pat The Bunny said:
A punk rock song won't ever change the world, but I can tell you about a couple that changed me.

bodhisatta said:
i recommend common sense and figuring it out.

These are the TEKs I use. They're all as cheap and easy as possible, just like your mom.


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Offlinemackrel
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Re: question on the ability to enhance potency, try to follow me here [Re: 36fuckin5]
    #22132509 - 08/23/15 07:25 PM (8 years, 5 months ago)

That is a good point unless you have a really good extraction tek which is probably not going to be any easier equipment wise than GC.


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Invisibleazur
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Re: question on the ability to enhance potency, try to follow me here [Re: inked4life]
    #22133614 - 08/24/15 01:02 AM (8 years, 5 months ago)

Grow pe or a non cube. Give it all the proper things to make it happy and healthy.
Keep it simple.


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Offlineinked4life
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Re: question on the ability to enhance potency, try to follow me here [Re: azur]
    #22134597 - 08/24/15 09:10 AM (8 years, 5 months ago)

yeah i had a stoner moment guys, i really didnt think i would have gotten the responses i did. i just thought of it n posted to see what response id would get or if it something that really held weight ti the subject. thanks fir ur responses people, have a great day


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Offlinegrowguru
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Re: question on the ability to enhance potency, try to follow me here [Re: inked4life]
    #22197176 - 09/06/15 01:06 PM (8 years, 4 months ago)

I have found that Black Alkaline Fulvic Trace Mineral infused water is the best extraction for the actives... crazy but try it some time. You can get it at Whole Foods.


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