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Rebelutionsssss
Mdmazing



Registered: 07/23/14
Posts: 13,137
Loc: San Francisco
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i think it really depends on the person. sure if you're eating grams a night every weekend then you're going to be doing unnecessary damage but if you watch your dose and take preventative steps i feel you'll have minimal negative side effects. ive discussed MDMA's effects thoroughly with other people that have used the drug and most if not all have said that besides the comedown they feel that theres been no lasting depression.
-------------------- : To define is to confine.
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Bitter Cactus
reformed bad boy


Registered: 01/26/12
Posts: 11,773
Loc: Alberta, Canada
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Re: How dangerous do you guys feel MDMA truly is? [Re: Rebelutionsssss]
#22076108 - 08/11/15 12:03 PM (8 years, 5 months ago) |
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How does taking an antidepressant compare to the experience of MDMA lol.
Just being all like "well mdma JUST increases serotonin levels" is like saying "the ocean is just a big pool of water".
Look it up dude, MDMA is neurotoxic and destroys the serotonin axons. I don't feel like researching it again but I read it before and it is true it is not bullshit.
-------------------- Taking acid and thinking you are a better man is a lot different then actually becoming a better man.
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Sophistic Radiance
Free sVs!


Registered: 07/11/06
Posts: 43,135
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Re: How dangerous do you guys feel MDMA truly is? [Re: Rebelutionsssss]
#22076113 - 08/11/15 12:04 PM (8 years, 5 months ago) |
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Definitely varies from person to person. I once had an MDMA come down give me a panic attack which in turn spurred ongoing problems with panic and anxiety that lasted for months. But these were two of those press pills where you just have no way of knowing what's in them. Whatever it was, it was potent as fuck, and not meth. Meth doesn't make me want to hump my furniture even at high doses.
I do like MDMA but I agree that it's to be treated with care and not to be taken too lightly. Frequent high dose use obviously has lasting effects on users, whether they acknowledge it or not.
-------------------- Enlil said: You really are the worst kind of person.
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Rebelutionsssss
Mdmazing



Registered: 07/23/14
Posts: 13,137
Loc: San Francisco
Last seen: 2 years, 2 months
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Quote:
BlindSophist said: Definitely varies from person to person. I once had an MDMA come down give me a panic attack which in turn spurred ongoing problems with panic and anxiety that lasted for months. But these were two of those press pills where you just have no way of knowing what's in them. Whatever it was, it was potent as fuck, and not meth. Meth doesn't make me want to hump my furniture even at high doses.
I do like MDMA but I agree that it's to be treated with care and not to be taken too lightly. Frequent high dose use obviously has lasting effects on users, whether they acknowledge it or not.
evidence or GTFO
-------------------- : To define is to confine.
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Sophistic Radiance
Free sVs!


Registered: 07/11/06
Posts: 43,135
Loc: Center of the Universe
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Re: How dangerous do you guys feel MDMA truly is? [Re: Rebelutionsssss]
#22076136 - 08/11/15 12:14 PM (8 years, 5 months ago) |
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You won't find much more reliable evidence of my own personal experiences than my anecdotes.
-------------------- Enlil said: You really are the worst kind of person.
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ReposadoXochipilli
Here, there, inbetween



Registered: 08/30/05
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Re: How dangerous do you guys feel MDMA truly is? [Re: Bitter Cactus]
#22076157 - 08/11/15 12:27 PM (8 years, 5 months ago) |
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All this talk is of extreme abuse, of course those choices will have repercussions.
With moderate use I have no noticeable side effects after 11 years and probably 50 doses in that time. No bad come downs, no blue Tuesday's. Treat your mind and chemicals with respect and they will treat you right in return.
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Bitter Cactus
reformed bad boy


Registered: 01/26/12
Posts: 11,773
Loc: Alberta, Canada
Last seen: 8 years, 4 months
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Every dose is neurotoxic.
-------------------- Taking acid and thinking you are a better man is a lot different then actually becoming a better man.
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ReposadoXochipilli
Here, there, inbetween



Registered: 08/30/05
Posts: 7,501
Loc: Sand and sunshine
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Re: How dangerous do you guys feel MDMA truly is? [Re: Bitter Cactus]
#22076175 - 08/11/15 12:34 PM (8 years, 5 months ago) |
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And every breath is one closer to death
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Sophistic Radiance
Free sVs!


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Re: How dangerous do you guys feel MDMA truly is? [Re: Bitter Cactus]
#22076177 - 08/11/15 12:36 PM (8 years, 5 months ago) |
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Quote:
Bitter Cactus said: Every dose is neurotoxic.
Dude, seriously, would it kill you to look up the source for your claims?
-------------------- Enlil said: You really are the worst kind of person.
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Rebelutionsssss
Mdmazing



Registered: 07/23/14
Posts: 13,137
Loc: San Francisco
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a microgram of mdma is neurotoxic?
-------------------- : To define is to confine.
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Moonshoe
Blue Mantis


Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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Re: How dangerous do you guys feel MDMA truly is? [Re: danielx]
#22076200 - 08/11/15 12:44 PM (8 years, 5 months ago) |
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Quote:
danielx said:
Quote:
Moonshoe said: real pure mdma at reasonable doses worke proper precautions (stay hydrated. Cool off, don't mix with certain other drugs etc) is very safe . It's safer then horse riding.
It's definitely one of the safer recreational drugs .
Not sure how you are even quantifying that. Safer as far as dying, but I don't think is a very good indicator of how inherently safe a chemical is on the brain/body.
Google Dr. Nutt he does research on MDMA the thing about horse riding is his quote.
https://en.m.wikipedia.org/wiki/David_Nutt
As you can see from his graph he considers MDMA to be one of the least harmful drugs.
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Everything I post is fiction.
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SARAtonin
Violent Dreams


Registered: 09/28/11
Posts: 15,907
Loc: Deutschland
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Re: How dangerous do you guys feel MDMA truly is? [Re: Rebelutionsssss]
#22076210 - 08/11/15 12:46 PM (8 years, 5 months ago) |
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I believe regulated MDMA coupled with drug education is very safe but unregulated MDMA is just asking for more deaths.
-------------------- God kills indiscriminately and so shall we. For no creatures under God are as we are none so like him as ourselves. Want to join a cult? Click for details…
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sh4d0ws
LSx


Registered: 02/26/08
Posts: 12,086
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Re: How dangerous do you guys feel MDMA truly is? [Re: Bitter Cactus]
#22076214 - 08/11/15 12:47 PM (8 years, 5 months ago) |
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Quote:
Bitter Cactus said: Every dose is neurotoxic.
Please provide some sources, or stop saying that.
While I agree MDMA has a lot of addiction potential, most people don't use it daily or even weekly.
For me, while I was a carefree youth, I dosed up to a gram at time some days. I now I barely even use it once every two or three years, but it definitely can be dangerous in certain circumstances.
As far as neurotoxicity goes, it definitely could be...especially at high doses...but no one actually has sound scientific proof of this.
More research needs to be done, and you can thank organizations like MAPS for paving the way for that kind of stuff.
But to claim every single dose is neurotoxic when even the professionals still don't know, is just wrong. You are misleading people.
You do not know. The methamphetamines that you abused yourself (talking to B_C) were probably much more harmful to you than MDMA will ever be.
Because MDMA loses its magic, and doesn't work well the next day or continuous days in a row, it clearly is not abused as much as meth.
Please please please provide sources if you're going to claim stuff like that, if not...don't say anything at all!
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OsculateOfDemise



Registered: 06/24/05
Posts: 2,879
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Re: How dangerous do you guys feel MDMA truly is? [Re: sh4d0ws]
#22076256 - 08/11/15 12:56 PM (8 years, 5 months ago) |
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There's smarter ways to take it but there was definitely a time in my life where I was overusing and abusing. Taking it all weekend, or every weekend for months. Suicide sundays were horribly harsh and I literally felt very etarded for a while there. Roll safe, kiddies.
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Aiko Aiko



Registered: 05/13/05
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Loc: Lazy River Road
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Re: How dangerous do you guys feel MDMA truly is? [Re: OsculateOfDemise]
#22076324 - 08/11/15 01:13 PM (8 years, 5 months ago) |
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There is probably no other illicit chemical where moderation is more importnat when it comes to toxicity and actual consequences..barring addictive substances like opiates and cocaine than MDMA. There is no such thing as moderation with cocaine and with opiates, you will become dependent after a while physically and psychologically and psychologically respectively. I have suffered from serotonin syndrome as well as crazy depressive states directly attributed to over MDMA indulgence and it is god awful! Once a month is the MAX I would recommend and even that is probably too much. Im 35 and I do it once every year or two and thats all I can handle. Be safe!
Edited by Aiko Aiko (08/11/15 01:15 PM)
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Love_spirit
Circle Of Power


Registered: 07/18/15
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Re: How dangerous do you guys feel MDMA truly is? [Re: Rebelutionsssss]
#22076354 - 08/11/15 01:18 PM (8 years, 5 months ago) |
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I also had my own adventures with it. When I was much younger my friends used to rib me for taking it all the time. My nickname was E. They could see how it was making me idiotic. After enough time my memory really started going to shit. Also had the my precious vibes going. I'll cut you if you touch my stash. Could have been proven to cause parkinsons and brain cancer and I still would have taken it again after that first dose.
Great for once a year though.
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Bitter Cactus
reformed bad boy


Registered: 01/26/12
Posts: 11,773
Loc: Alberta, Canada
Last seen: 8 years, 4 months
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Re: How dangerous do you guys feel MDMA truly is? [Re: Aiko Aiko]
#22076363 - 08/11/15 01:19 PM (8 years, 5 months ago) |
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http://www.ncbi.nlm.nih.gov/pubmed/11888574
The ring-substituted amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA) or "Ecstasy" is widely used a recreational drug. It stimulates the release and inhibits the reuptake of serotonin (5-HT) and other neurotransmitters such as dopamine to a lesser extent. The acute boost in monoamine activity can generate feelings of elation, emotional closeness, and sensory pleasure. In the hot and crowded conditions of raves/dances, mild versions of the serotonin syndrome often develop, when hyperthermia, mental confusion, and hyperkinesia predominate. Rest in a cooler environment generally reverses these problems, although they can develop into medical emergencies, which occasionally prove fatal. This acute serotonergic overactivity is exacerbated by the high ambient temperatures, overcrowding (aggregate toxicity), and use of other stimulant drugs. The on-drug experience is generally followed by negative moods, with 80--90% of weekend Ecstasy users reporting 'midweek blues', due probably to monoaminergic depletion. Single doses of MDMA can cause serotonergic nerve damage in laboratory animals, with repeated doses causing extensive loss of distal axon terminals. Huether's explanatory model for this 5-HT neurotoxicity will be briefly described. There is an increasing body of evidence for equivalent neuropsychobiological damage in humans. Abstinent regular Ecstasy users often show: reduced cerebrospinal 5-HIAA, reduced density of 5-HT transporters, blunted response to a fenfluramine challenge, memory problems, higher cognitive deficits, various psychiatric disorders, altered appetite, and loss of sexual interest. Functional deficits may remain long after drug use has ceased and are consistent with serotonergic axonal loss in higher brain regions.
I just googled it and that is the first thing I found. Overall I think MDMA is the worst drug for your brain, but people don't abuse it as hard as other drugs.
-------------------- Taking acid and thinking you are a better man is a lot different then actually becoming a better man.
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Sophistic Radiance
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Registered: 07/11/06
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Re: How dangerous do you guys feel MDMA truly is? [Re: Bitter Cactus]
#22076409 - 08/11/15 01:28 PM (8 years, 5 months ago) |
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Methamphetamine is also a serotonin releasing agent, in addition to being a very powerful dopamine releasing agent... dopamine is more neurotoxic in high concentrations than serotonin, capable of actually killing entire neurons, an order of magnitude greater harm than merely damaging their axons.
http://www.ncbi.nlm.nih.gov/pubmed/17105911
-------------------- Enlil said: You really are the worst kind of person.
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MagicalOrangutan
Curious Cat



Registered: 06/29/12
Posts: 3,538
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That's messed up, I didn't know that
Dopamine euphoria still kicks ass tho
-------------------- On the ground you lay, with your dogs you pray, at a neon hieroglyph sky you gaze Hugging your mind, praying to survive, feeling the love of the hieroglyphs in the sky We all need more love, and mainly less hate Hate is the blind that covers the heart's eye That makes the heart's eye cry Locked deep away in the skies of our minds It's all in the mind
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Bitter Cactus
reformed bad boy


Registered: 01/26/12
Posts: 11,773
Loc: Alberta, Canada
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Re: How dangerous do you guys feel MDMA truly is? [Re: MagicalOrangutan]
#22076457 - 08/11/15 01:37 PM (8 years, 5 months ago) |
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I know meth is neurotoxic too, but I have done massive doses that should have killed me with it and besides the comedown I always woke up feeling fine to go about my day after a good amount of sleep. MDMA one dose I feel so sketchy the next day and get depressed the whole next week. I just feel it is worse and if you abused MDMA like people abused meth the damage would be way more severe.
-------------------- Taking acid and thinking you are a better man is a lot different then actually becoming a better man.
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