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Yukon Cornelius
Bumble Wrangler



Registered: 09/01/13
Posts: 1,348
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Re: How dangerous do you guys feel MDMA truly is? [Re: Malcolm_Xtasy]
#22087588 - 08/13/15 02:44 PM (8 years, 5 months ago) |
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To be expected, I often shut the fuck up when it comes to these things but I feel like flexing my reasoning skills a bit.
-------------------- "I didn't know chicken's wore suspenders" - Towelie
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Sophistic Radiance
Free sVs!


Registered: 07/11/06
Posts: 43,135
Loc: Center of the Universe
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Re: How dangerous do you guys feel MDMA truly is? [Re: Yukon Cornelius] 1
#22087605 - 08/13/15 02:47 PM (8 years, 5 months ago) |
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I hope that means you don't really think there's no such thing as different highs from different strains of weed
-------------------- Enlil said: You really are the worst kind of person.
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404
error


Registered: 08/20/10
Posts: 14,539
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I like how both posters after me said i was wrong and then used what i said as an argument against me "neurotransmitters are just one part of the picture" edit- maybe not so much beanhead
The idea behind these drugs increasing neurogenesis is relatively new iirc
Edited by 404 (08/13/15 03:10 PM)
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Sophistic Radiance
Free sVs!


Registered: 07/11/06
Posts: 43,135
Loc: Center of the Universe
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Re: How dangerous do you guys feel MDMA truly is? [Re: 404]
#22087701 - 08/13/15 03:09 PM (8 years, 5 months ago) |
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I'd just as soon assume that neurogenesis is somehow induced through the selective serotonin reuptake inhibition so it's just kinda like
-------------------- Enlil said: You really are the worst kind of person.
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404
error


Registered: 08/20/10
Posts: 14,539
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i wonder what te mechanis behind mushrooms inducing neurogenesis. Maybe it's how close the molecule is to DMT, and if DMT really is released during sleep, and sleep is where new pathways are strengthened, maybe pailocin achieves this via those routes?
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Beanhead
IS IRONIC PARADOX


Registered: 10/11/08
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Re: How dangerous do you guys feel MDMA truly is? [Re: 404] 1
#22087720 - 08/13/15 03:14 PM (8 years, 5 months ago) |
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Quote:
404 said: I like how both posters after me said i was wrong and then used what i said as an argument against me "neurotransmitters are just one part of the picture" edit- maybe not so much beanhead
The idea behind these drugs increasing neurogenesis is relatively new iirc
I agreed with your post really.
I just don't think "increase parameter x" therefore "y" is complete :P.
Edited by Beanhead (08/13/15 03:14 PM)
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Moonshoe
Blue Mantis


Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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Re: How dangerous do you guys feel MDMA truly is? [Re: Beanhead]
#22087814 - 08/13/15 03:34 PM (8 years, 5 months ago) |
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No I have never done meth.
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Everything I post is fiction.
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Gottaloveacid
Weedbass



Registered: 10/20/14
Posts: 3,421
Loc: Colorado, USA
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Re: How dangerous do you guys feel MDMA truly is? [Re: 404]
#22087913 - 08/13/15 03:53 PM (8 years, 5 months ago) |
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Quote:
404 said:
Quote:
BlindSophist said:
Quote:
Yukon Cornelius said: It is true that the brain has the ability to heal itself, the idea that you can't restore a set number of neurons in your brain is an antiquity from an era in science where we were barely scratching the surface of neurology.
Hell we still have a lot of shit to figure out, that's why I get my jimmies rustled when someone uses the term "chemical imbalance" to justify psychiatric medication, as if there is a finite amount of neurotransmitters that every individual should have.
I used to take issue with the "chemical imbalance" thing but after experiencing a rapid remission of a huge variety of harrowing psychiatric issues after starting a certain medication regimen, I put a bit more stock into it. Not that I think antidepressants are the answer to most problems or that pill pushers know what the fuck they are talking about except by accident at times.
don't antidepressants like prozac work by increasing neurogenesis in select regions that deal directly with mood and emotional regulation? neurotransmitters are just one part of the picture.
Anything that stimulates neurons without also damaging them promotes neurogenesis. That is why music helps people with dementia. That is why weed can paradoxically improve memory while not stoned (the hippocampus has an extremely high concentration of CB1 receptors)
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 The greatest story ever told is the story that never ends! wubba lubba dub dubstep
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Malcolm_Xtasy
Oh baby what Is you doin??



Registered: 04/04/12
Posts: 13,851
Loc:
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Re: How dangerous do you guys feel MDMA truly is? [Re: Moonshoe] 1
#22087937 - 08/13/15 03:58 PM (8 years, 5 months ago) |
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Quote:
Moonshoe said: No I have never done meth.
So you were talking outta your ass?
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That is why weed can paradoxically improve memory while not stoned (the hippocampus has an extremely high concentration of CB1 receptors)
GLA, explain what you mean by this?
-------------------- I'm stupid, Enlil is smart. I'm ugly, Enlil is beautiful. I'm a loser, Enlil is a winner. Someday, I hope to be like Enlil but secretly know I never will.
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404
error


Registered: 08/20/10
Posts: 14,539
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Re: How dangerous do you guys feel MDMA truly is? [Re: Gottaloveacid]
#22088119 - 08/13/15 04:43 PM (8 years, 5 months ago) |
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That's what i was trying to say earlier but couldnt get the words out
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Yukon Cornelius
Bumble Wrangler



Registered: 09/01/13
Posts: 1,348
Loc: Peppermint Mines
Last seen: 5 hours, 35 minutes
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Quote:
Malcolm_Xtasy said: Science

Ok after reading that I realize that was an uninformed statement, it was foolish of me to jump to that conclusion without anything to back it up.
Bit of a moment.
However that's not to say it is effective in treating depression. http://www.health.harvard.edu/mind-and-mood/what_are_the_real_risks_of_antidepressants
The article has legitimate references, also more recent than the study you posted.
Quote:
BlindSophist said: I hope that means you don't really think there's no such thing as different highs from different strains of weed
Please don't involve arguments from another thread here. The assumption that everyone made about me not thinking there are different highs is stupid. I just don't think the strain name gives any guarantee of a consistent effect is all.
-------------------- "I didn't know chicken's wore suspenders" - Towelie
Edited by Yukon Cornelius (08/13/15 04:54 PM)
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Boomertown
Psychonaut



Registered: 06/21/15
Posts: 183
Last seen: 5 years, 4 months
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Re: How dangerous do you guys feel MDMA truly is? [Re: Yukon Cornelius]
#22088160 - 08/13/15 04:54 PM (8 years, 5 months ago) |
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I've done an estimated 400+ Ecstasy Pills and pure MDMA countless times as well. Over the course of the last 10 years of my life. Almost all of the pills were in my early usage 15-18 years old. Then I stopped MDMA period for about 3 years and started taking pure molly once i moved from my hometown. Although I don't take it much anymore due to the fact of people having random MDMA look a likes going around.
But I would say that I have 0 side effects from any of my usage of MDMA over the years. As long as you stay hydrated and don't binge for months on it and make sure its 100% pure and not cut with some random shit. I feel its quite a safe drug.
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Malcolm_Xtasy
Oh baby what Is you doin??



Registered: 04/04/12
Posts: 13,851
Loc:
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Re: How dangerous do you guys feel MDMA truly is? [Re: Boomertown] 1
#22088196 - 08/13/15 05:01 PM (8 years, 5 months ago) |
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Quote:
Then I stopped MDMA period for about 3 years and started taking pure molly once i moved from my hometown.
-------------------- I'm stupid, Enlil is smart. I'm ugly, Enlil is beautiful. I'm a loser, Enlil is a winner. Someday, I hope to be like Enlil but secretly know I never will.
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The Doobie Dude


Registered: 04/28/13
Posts: 13,498
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Re: How dangerous do you guys feel MDMA truly is? [Re: Boomertown]
#22088208 - 08/13/15 05:03 PM (8 years, 5 months ago) |
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Quote:
Boomertown said: I've done an estimated 400+ Ecstasy Pills and pure MDMA countless times as well. Over the course of the last 10 years of my life. Almost all of the pills were in my early usage 15-18 years old. Then I stopped MDMA period for about 3 years and started taking pure molly once i moved from my hometown. Although I don't take it much anymore due to the fact of people having random MDMA look a likes going around.
But I would say that I have 0 side effects from any of my usage of MDMA over the years. As long as you stay hydrated and don't binge for months on it and make sure its 100% pure and not cut with some random shit. I feel its quite a safe drug.
what up bassfreak
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"There are a million reasons to drink and one just popped into my head. If a man can't drink when he's living how the Hell can he drink when he's dead?" - Irish Limerick I PLURed once because it was PLUR or die. - D.M.T.
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404
error


Registered: 08/20/10
Posts: 14,539
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Re: How dangerous do you guys feel MDMA truly is? [Re: The Doobie Dude] 1
#22088214 - 08/13/15 05:04 PM (8 years, 5 months ago) |
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that's clearly not bassfreak
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The Doobie Dude


Registered: 04/28/13
Posts: 13,498
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Re: How dangerous do you guys feel MDMA truly is? [Re: 404]
#22088221 - 08/13/15 05:05 PM (8 years, 5 months ago) |
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he had to know the ban was coming he preemptively made the accountlol
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"There are a million reasons to drink and one just popped into my head. If a man can't drink when he's living how the Hell can he drink when he's dead?" - Irish Limerick I PLURed once because it was PLUR or die. - D.M.T.
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SirShroomsAlott
Howdy



Registered: 05/15/14
Posts: 6,945
Loc: United States
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Re: How dangerous do you guys feel MDMA truly is? [Re: Malcolm_Xtasy]
#22088222 - 08/13/15 05:06 PM (8 years, 5 months ago) |
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Noob here! How do you take mdma that comes in like a rock/crystal form, buy gel caps and put it in there? And what would be a TRULY good dose for a first time, like blow you away type of first time, being overwhelmed hasn't been an issue on any drug so far but being underwhelmed is an understatement. I don't want to get a feel for it or any of that like people recommend with psychs, I'd rather jump right in because my first time with all drugs has been disappointing by doing that.
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Moonshoe
Blue Mantis


Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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Re: How dangerous do you guys feel MDMA truly is? [Re: Malcolm_Xtasy]
#22088226 - 08/13/15 05:07 PM (8 years, 5 months ago) |
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I have done a lot of research, read a lot of stuff and watched every documentary about Meth I could find.
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Everything I post is fiction.
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404
error


Registered: 08/20/10
Posts: 14,539
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Quote:
BlindSophist said: I hope that means you don't really think there's no such thing as different highs from different strains of weed
to be fair, choosing when to harvest has a lot to do with how the cannabinoid ratio turns out as well. you can get inconsistent levels from that alone.
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Gottaloveacid
Weedbass



Registered: 10/20/14
Posts: 3,421
Loc: Colorado, USA
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Re: How dangerous do you guys feel MDMA truly is? [Re: Malcolm_Xtasy]
#22088237 - 08/13/15 05:10 PM (8 years, 5 months ago) |
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Quote:
Malcolm_Xtasy said:
Quote:
Moonshoe said: No I have never done meth.
So you were talking outta your ass?
Quote:
That is why weed can paradoxically improve memory while not stoned (the hippocampus has an extremely high concentration of CB1 receptors)
GLA, explain what you mean by this?
I'll look for a study after dinner, but basically weed can help improve your memory (obviously after you stop using it for a week or so to get rid of all the THC built up if you smoke a lot) because since there are so many CB1 receptors in the hippocampus (huge memory center in the brain), when you smoke weed it stimulates that area a LOT.
Since the THC is stimulating the high number of CB1 receptors, it is promoting neurogenisis in that area of the brain, which will improve memory as that is the hippcampus's main purpose.
--------------------
 The greatest story ever told is the story that never ends! wubba lubba dub dubstep
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