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OfflineD.M.T
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Registered: 10/31/09
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Re: People selling "LSB" at a party? [Re: ThatKidWithTheFace]
    #22037230 - 08/03/15 11:29 AM (8 years, 5 months ago)

Quote:

ThatKidWithTheFace said:
What the fuck happened to this place? Y'all done turned into a bunch of fucking pussies.

What's wrong with N-bome? Absolutely fucking nothing and the real heads know it.



Shroomery has always been full of drug elitists. That's why I post about LSD in ODD instead of Psychedelic Experience since that's usually where they hide.


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OfflineBassfreak
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Re: People selling "LSB" at a party? [Re: ThatKidWithTheFace]
    #22037237 - 08/03/15 11:32 AM (8 years, 5 months ago)

Quote:

ThatKidWithTheFace said:
What the fuck happened to this place? Y'all done turned into a bunch of fucking pussies.

What's wrong with N-bome? Absolutely fucking nothing and the real heads know it.







you know people have ODed and died from eating 2 hits right? i know people personally who have done that and has seizures too

youre calling us pussies? lol no i assure you its the other way around. sorry but people like me who dose hard,  we cant afford to eat 10 strips and fucking die

like i said, i know a kid who ate 2 and had seizures and hes never had a seizure in his life until then. sorry but if not wanting to have a seizure on a totally recreational dose makes me a pussy then i guess i am lol

nothing about NBOME is good. im sorry you guys cant find real drugs tho


--------------------
Tom Brady is a God

Free Tom Brady


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OfflineBassfreak
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Re: People selling "LSB" at a party? [Re: D.M.T]
    #22037243 - 08/03/15 11:34 AM (8 years, 5 months ago)

Quote:

D.M.T said:
Quote:

ThatKidWithTheFace said:
What the fuck happened to this place? Y'all done turned into a bunch of fucking pussies.

What's wrong with N-bome? Absolutely fucking nothing and the real heads know it.



Shroomery has always been full of drug elitists. That's why I post about LSD in ODD instead of Psychedelic Experience since that's usually where they hide.





it has nothing to do with being an elitist. if NBOME wasnt a drug you could OD on then im sure id probly wanna try it. but thats not the reality of the situation

im not an elitist, im just a responsible drug user. theres a HUGE fucking difference


--------------------
Tom Brady is a God

Free Tom Brady


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InvisiblePsychonautica
Cuddly Wuddly Fuccboi


Registered: 04/20/15
Posts: 10,854
Loc: Free Soul & IISkuNkII Flag
Re: People selling "LSB" at a party? [Re: Bassfreak]
    #22037248 - 08/03/15 11:36 AM (8 years, 5 months ago)

Who the fuck does drugs to be safe?

Just because you can overdose on it doesn't mean you can't use it responsibly. You can overdose on aspirin too. Hahaha.

Your arguments are so convoluted.


--------------------
The chances of you even being born, Were forty million to one. There's two parts of the statistic And I want you to live through one
3/8/95 - 7/10/15 Rest In Paradise, Brother.
Sheekle said:
yeah, i said i was afraid of psychonautica


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InvisibleMalcolm_Xtasy
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Re: People selling "LSB" at a party? [Re: Psychonautica] * 2
    #22037251 - 08/03/15 11:37 AM (8 years, 5 months ago)

I would hardly call the arguments. That's being super generous


--------------------
I'm stupid, Enlil is smart.
I'm ugly, Enlil is beautiful.
I'm a loser, Enlil is a winner.
Someday, I hope to be like Enlil but secretly know I never will.


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OfflineCoincidentiaoppositorum
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Re: People selling "LSB" at a party? [Re: Coincidentiaoppositorum]
    #22037252 - 08/03/15 11:37 AM (8 years, 5 months ago)

The primary health concerns about LSD use are related to psychological health rather than risk of physical damage to the body or brain. As senior LSD researcher Dr. David Nichols, Distinguished Chair of Pharmacology at Purdue University and head of one of the world's top LSD research labs, stated in his 2004 review article on hallucinogens, "There is no evidence that any of the hallucinogens, even the very powerful semisynthetic LSD, causes damage to any human body organ. [...] Hallucinogens do not cause life-threatening changes in cardiovascular, renal, or hepatic function because they have little or no affinity for the biological receptors and targets that mediate vital vegetative functions."1 Deaths resulting from the pharmacological effects of LSD are rare to non-existent. (-erowid)

LSD is in general physically benign, where NBOMe compounds cause unpredictable vassoconstriction and toxicity, the vassoconstriction can result in loss of limbs or use of limbs or even death. It's like playing russian roulette, you can take a dose and be fine, then take the same dose from the same batch a week later and die.

LSD is safe...

...While NBOMEs are unwelcome toxins infesting the psychedelic community...they are great for research but not for recreation or human consumption of this kind.

It is interesting that a methyl substitution cuts phenethylamine activity, an ethyl substitution early kills activity and propyl or butyl does kill activity...

...so there was no reason to believe large substitutions on the amine nitrogen of phenethylamines would do anything but kill.activity...then these N-benzoyl substitutions to the amine nitrogen were explored and actually INCREASED the potency GREATLY! And nobody  this conning!

2C-I (2,5-dimethoxy-4-iodo-phenethylamine) is active at 10-30mgs

While if you take 2C-I and hold it in reductive alkylation with 2-methoxybenzaldehyde, then reducing the imine with sodium borohydride (or by direct reaction with triacetoxyborohydride), you increase potency of 2C-I from 10-30mgs to 25I active at 50ugs to 1.5mgs...

...and NBOMe's are fascinating for chemistry and pharmacology (having a binding affinity at 5-HT2A, 5-HT2C, 5-HT6, μ-opioid ,H1
,5-HT2B, κ-opioid)
But need to be eliminated as recreational compounds, they are simply to dangerous to function as recreational agents.

-E. Borodin


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OfflineBassfreak
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Re: People selling "LSB" at a party? [Re: Psychonautica]
    #22037253 - 08/03/15 11:37 AM (8 years, 5 months ago)

Quote:

Psychonautica said:
Who the fuck does drugs to be safe?

Just because you can overdose on it doesn't mean you can't use it responsibly. You can overdose on aspirin too. Hahaha.

Your arguments are so convoluted.





who does drugs to be safe?

literally millions of drug users. thats who


--------------------
Tom Brady is a God

Free Tom Brady


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InvisiblePsychonautica
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Registered: 04/20/15
Posts: 10,854
Loc: Free Soul & IISkuNkII Flag
Re: People selling "LSB" at a party? [Re: Psychonautica] * 1
    #22037255 - 08/03/15 11:37 AM (8 years, 5 months ago)

Also telling us we can't find real drugs when you openly cried about not being able to find Meth is fucking hilarious.


--------------------
The chances of you even being born, Were forty million to one. There's two parts of the statistic And I want you to live through one
3/8/95 - 7/10/15 Rest In Paradise, Brother.
Sheekle said:
yeah, i said i was afraid of psychonautica


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OfflineTheGreenArrow
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Re: People selling "LSB" at a party? [Re: ThatKidWithTheFace] * 2
    #22037256 - 08/03/15 11:37 AM (8 years, 5 months ago)

:lolsy: Except the fact that people have died taking the N-bombe series... This thread is ridiculous.  If LSD were a concert pianist playing across your 5-HT2A receptors, Nbombes would be a dominatrix fist fucking them. 

Not EVEN a safe chemical for humans to try.  :nojustno:


--------------------
A human being should be able to change a diaper, plan an
invasion, butcher a hog, design a building, conn a ship, write a
sonnet, balance accounts, build a wall, set a bone, comfort the
dying, take orders, give orders, cooperate, act alone, solve an
equation, analyze a new problem, pitch manure, program a
computer, cook a tasty meal, fight efficiently, die gallantly.
Specialization is for insects.- Robert A. Heinlein
Saint RedBow of the Shroomey Loomey-Patron Saint of Sandbaggin Sumbitchs


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OfflineYukon Cornelius
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Re: People selling "LSB" at a party? [Re: Bassfreak]
    #22037257 - 08/03/15 11:38 AM (8 years, 5 months ago)

Bassfreak just drop it, this thread isn't about RC's vs. classic psychedelics.

Back to OP, he said he informed everyone he sold it to that it was 25-b.

The real asshole is the guy reselling it as "LSB", which is fucking criminal.


--------------------
"I didn't know chicken's wore suspenders" - Towelie



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Offlinelood_dood
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Re: People selling "LSB" at a party? [Re: LoGerLunD]
    #22037260 - 08/03/15 11:39 AM (8 years, 5 months ago)

A lotta hate for RC's! Not all RC's are bad. I really love AL LAD and I've never heard of anyone ODing on it, although I've heard of people doing crazy large doses of it and coming out OK. For the most part it seems safe.

I like it because it is shorter than LSD, and for me it has always been more visually intense.... granted, AL LAD is also made out of LSD from the start but eh whatever :shrug:

That aside, NBOME and any psychedelic that has any known and documented chance of killing you is pretty irresponsible. I mean, if people are actively looking for it and know the risks, it's on them. I personally couldn't sell anyone something I think could kill them.

On one hand I gotta blame ignorance and/or selling chems under false names, but more so the prohibition. More people are dying as a result of the ban on cannabis (synthetic cannabinoids will fuck you up!), LSD, and psilocybin than if it were legal  :shakefist:


--------------------
:brainondrugs: :dna: :tinfoil: BILL NYE IS A LIZARD. THEY'RE ALL LIZARDS! :tinfoil: :dna: :brainondrugs:


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OfflineBassfreak
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Re: People selling "LSB" at a party? [Re: Bassfreak]
    #22037263 - 08/03/15 11:39 AM (8 years, 5 months ago)

psychonautica, you clearly do not have the brain capacity to understand my point

on 2 hits its possible to OD and die. its happened before and will again in the future. what about eating 2 hits is irresponsible? fucking nothing. thats a normal recreational dose

and your telling me theres a possibility i could OD and die on a normal recreational dose? LOL yeah. so fucking safe bro

call me when you grow up kiddo


--------------------
Tom Brady is a God

Free Tom Brady


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InvisiblePsychonautica
Cuddly Wuddly Fuccboi


Registered: 04/20/15
Posts: 10,854
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Re: People selling "LSB" at a party? [Re: Bassfreak]
    #22037267 - 08/03/15 11:41 AM (8 years, 5 months ago)

I'm telling you that if you source your drugs like a retard there's no telling what can happen regardless of what drugs you're doing.

You're so fucking dense.

Also why are you melting because I like nbomes lmfao.


--------------------
The chances of you even being born, Were forty million to one. There's two parts of the statistic And I want you to live through one
3/8/95 - 7/10/15 Rest In Paradise, Brother.
Sheekle said:
yeah, i said i was afraid of psychonautica


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OfflineD.M.T
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Registered: 10/31/09
Posts: 10,991
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Re: People selling "LSB" at a party? [Re: Bassfreak] * 1
    #22037268 - 08/03/15 11:41 AM (8 years, 5 months ago)

When I dosed NBOMe it was still fresh and shiney and there were no complications or deaths yet. I'm pretty close to positive I was the first person to report several weeks of vasoconstriction from 400 micrograms of 25C-NBOMe.

You can overdose on a lot of the drugs we take. That's life as a drug user. I reserve my right to be killed off by the latest novel compound, and hopefully if that ever happened others could learn from it.


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OfflineBassfreak
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Re: People selling "LSB" at a party? [Re: Psychonautica]
    #22037270 - 08/03/15 11:42 AM (8 years, 5 months ago)

Quote:

Psychonautica said:
Also telling us we can't find real drugs when you openly cried about not being able to find Meth is fucking hilarious.





when did i cry about not being able to find meth?  :youseethisshit:

does meth exist in the northeast? no

do you live in the northeast? no. so what the fuck do you know?


--------------------
Tom Brady is a God

Free Tom Brady


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OfflineBassfreak
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Re: People selling "LSB" at a party? [Re: Psychonautica]
    #22037280 - 08/03/15 11:43 AM (8 years, 5 months ago)

Quote:

Psychonautica said:
I'm telling you that if you source your drugs like a retard there's no telling what can happen regardless of what drugs you're doing.

You're so fucking dense.

Also why are you melting because I like nbomes lmfao.





this has nothing to do with anything

congrats on losing the argument then trying to save face by bringing up irrelevant points tho :golfclap:


--------------------
Tom Brady is a God

Free Tom Brady


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OfflineCoincidentiaoppositorum
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Re: People selling "LSB" at a party? [Re: LoveNaborFuckHater]
    #22037283 - 08/03/15 11:44 AM (8 years, 5 months ago)

Quote:

LoveNaborFuckHater said:
Quote:

Coincidentiaoppositorum said:
The R isomer's ED50 puts its potency as higher than LSD in animal assays.




Quote:


while lysergic acid 2-butyl amide is more potent than LSD as a 5-HT1A agonist, it is slightly less potent as a 5-HT2A agonist, and so would probably be slightly less potent than LSD as a hallucinogen in humans.







ED-50
LSD = 48nmol/kg
LSB = 33nmol/kg

So in animal assays it's ED50 was actually higher, so I was not incorrect...Though I know these results have poor relation to human subjective effect induced by the compound.

Which is why I said more potent in animal assays.

Which can have poor relation to human activity, LSZ was more potent than LSD in animal assays as well, but had mixed results in human models...

-E. Borodin


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InvisiblePsychonautica
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Re: People selling "LSB" at a party? [Re: Bassfreak]
    #22037289 - 08/03/15 11:46 AM (8 years, 5 months ago)

I didn't lose any arguments..

I never argued that nbomes were safe.. I never even argued that they were better than lsd..

I just said I like them more.

I still like them more. How did I lose that argument?


--------------------
The chances of you even being born, Were forty million to one. There's two parts of the statistic And I want you to live through one
3/8/95 - 7/10/15 Rest In Paradise, Brother.
Sheekle said:
yeah, i said i was afraid of psychonautica


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OfflineD.M.T
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Re: People selling "LSB" at a party? [Re: Coincidentiaoppositorum]
    #22037292 - 08/03/15 11:47 AM (8 years, 5 months ago)

Quote:

Coincidentiaoppositorum said:
Which can have poor relation to human activity, LSZ was more potent than LSD in animal assays as well, but had mixed results in human models...

-E. Borodin




For me it would seem LSZ was slightly more potent for threshold and minimum effects than LSD, but doesn't have the jump.

ie. LSZ at 15mcg and 25mcg more potent than LSD at 15mcg and 25mcg, but LSZ at 50mcg not as potent as LSD at 50mcg


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InvisibleMalcolm_Xtasy
Oh baby what Is you doin??
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Registered: 04/04/12
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Re: People selling "LSB" at a party? [Re: Psychonautica] * 4
    #22037296 - 08/03/15 11:47 AM (8 years, 5 months ago)

You lost the argument when you decided to try and argue with Bassfreak
:justinwilson:


--------------------
I'm stupid, Enlil is smart.
I'm ugly, Enlil is beautiful.
I'm a loser, Enlil is a winner.
Someday, I hope to be like Enlil but secretly know I never will.


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