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Offlinexbloodwhipx

Registered: 02/24/12
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Opiates make anyone else lose their voice
    #22002220 - 07/26/15 10:16 PM (8 years, 6 months ago)

Ive noticed this everytime i take opiates for as long as ive been taking them. My voice gets really raspy like im losing it.

Anyone else have this effect or am i alone


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OfflineLove_spirit
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Registered: 07/18/15
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Re: Opiates make anyone else lose their voice [Re: xbloodwhipx]
    #22002287 - 07/26/15 10:45 PM (8 years, 6 months ago)

No, but cocaine makes me talk like Michael Jackson.


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InvisibleEminence
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Registered: 07/25/10
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Re: Opiates make anyone else lose their voice [Re: xbloodwhipx]
    #22002389 - 07/26/15 11:24 PM (8 years, 6 months ago)

Yup. If I take enough I end up talking like a cliche movie stoner.


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OfflineDrMambo
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Re: Opiates make anyone else lose their voice [Re: xbloodwhipx]
    #22002468 - 07/27/15 12:05 AM (8 years, 6 months ago)

Absolutely.

My buddies would be like, "Dude, lay off the hey-ron. You've got dope voice and yer not fooling anyone."

Seriously, I could spray nasal decongestants in my eyes to dialate my pupils and look almost normal, but that fucking audible was a dead giveaway.


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OfflineDrMambo
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Re: Opiates make anyone else lose their voice [Re: DrMambo]
    #22002474 - 07/27/15 12:07 AM (8 years, 6 months ago)

Perhaps it's due to smooth muscle relaxtion, like yer bowels....


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OfflineBig Worm
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Re: Opiates make anyone else lose their voice [Re: DrMambo]
    #22002488 - 07/27/15 12:12 AM (8 years, 6 months ago)

It just makes my voice sound raspy.

Like how you sound when you are way tired and falling asleep lol.



I did some dope and went out to eat with this girl who's my best friend.

She kept asking me why my voice sounded like it did lol, so I had to start being conscious of the way I sounded so it didn't seem like I was fucked up.


:drooling:


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OfflineEggtimer
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Registered: 05/04/13
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Re: Opiates make anyone else lose their voice [Re: xbloodwhipx]
    #22002536 - 07/27/15 12:36 AM (8 years, 6 months ago)

Quote:

xbloodwhipx said:
Ive noticed this everytime i take opiates for as long as ive been taking them. My voice gets really raspy like im losing it.

Anyone else have this effect or am i alone




Opiates cause the body to release histamines that's why you get itchy. It's the same thing that happens to people with allergies so I could see them messing with your voice.

http://www.ncbi.nlm.nih.gov/pubmed/7694026
Quote:

Opiates have long been known to cause the release of histamine from mast cells, resulting in several undesirable effects, such as hypotension, urticaria, pruritus, and tachycardia. The mechanism of this opiate response has remained unclear, although it is known to be non-immunological in nature. A survey of the histamine-releasing properties of a variety of opiates shows that the pharmacology of opiate-induced histamine release from mast cells is distinct from that of known opiate receptors. Although functional opiate receptors may exist on mast cells and may be capable of modulating IgE-mediated histamine release, there is no evidence that these receptors account for opiate-induced histamine release. Since other basic compounds have been suggested to release histamine from mast cells by directly activating G-proteins, it seems possible that morphine and endogenous opiates may also share this mechanism.




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