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Gottaloveacid
Weedbass



Registered: 10/20/14
Posts: 3,421
Loc: Colorado, USA
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Re: vaping shrooms [Re: s240779]
#21968210 - 07/19/15 11:45 PM (8 years, 6 months ago) |
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Don't know, but that is why I also believe vaporizing it would be very short. It probably is very similar to DMT, where when you smoke it or IV it, it only lasts for 5-15 minutes but when you take it orally, it lasts for much longer. MAO may have something to do with how it is metabolized in our systems, or maybe it is some other enzyme.
Someone needs to do research on things like that because your guess is frankly as good as mine
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 The greatest story ever told is the story that never ends! wubba lubba dub dubstep
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Achillita
Back to the basics



Registered: 05/26/14
Posts: 4,565
Last seen: 3 years, 10 days
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After a mushroom peak, You still keep tripping for a few hours. All the psilocybin is in your system. And it isn't just diminished instantly. It takes longer to break down than DMT because of the hydroxyl group. That's why mushrooms are active alone, but not DMT containing plants.
A MAOI is why ayahuasca lasts so long. Whenever I did syrian rue with mushrooms, I tripped much longer than without it.
Do you have any links saying that psilocybin only lasts 20 minutes when IVed? I did a quick search and couldn't find anything. But I do see how they would peak within 5 minutes as it forgoes digestion. Also, does LSD last the normal 10-12 hours, or does it also gone for in such a short time?
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Gottaloveacid
Weedbass



Registered: 10/20/14
Posts: 3,421
Loc: Colorado, USA
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Here is an article
http://www.ncbi.nlm.nih.gov/pubmed/25563444
download the entire study and read through it, about 1/4 of the way scrolled down it says how long people experienced the effects.
A direct quote:
All participants commented on the rapid onset of the drug effects. “like hitting a brick wall, and then you're somewhere else”
“I didn't feel anything go into my arm at all... then suddenly you disappear... you just take off”
These intense effects lasted 10-15 minutes after which they gradually subsided. Effects were described as 'barely noticeable' about 60 minutes after the injection."
And to answer your question, from reading reports of people who have tried iv LSD, the effects take the same 15-30 minutes to kick in post injection, and the effects last for the same duration as if you took it any other way (IM, sublingual, oral, intraocular, etc).
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 The greatest story ever told is the story that never ends! wubba lubba dub dubstep
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pureenergy13
fitting right in there


Registered: 08/09/11
Posts: 442
Last seen: 5 years, 7 months
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RoA doesn't have that drastic of an effect on duration. It certainly changes the duration to an extent. IME that's largely up to the chemical itself. For instance, I've done MDMA orally and insufflated. Its still very roughly the same duration, but insufflated MDMA comes on faster and is over faster, but only about an hour so. Certain RoA's have a longer or shorter duration simply by their method of processing the chemical; i.e. oral administration takes longer to process anything due to the nature of digestion, as opposed to IV which administers the substance directly into the blood and thus approaches the blood-brain barrier much quicker.
I have no schooling on such things, so take my word with a grain of salt, but it seems kind of common sense to me.
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Achillita
Back to the basics



Registered: 05/26/14
Posts: 4,565
Last seen: 3 years, 10 days
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IMO, that's weird as hell. Other than the onset of the effects being sped up, I can't see why psilocybin would be metabolized faster than if ingested. I know that bill has IVed 4-ACO-DMT, which is nearly exact same as psilocybin and only tripped for around the same duration.
I wonder why are the effects are so sped up though. Maybe it's because of how long it takes the chemical to reach the brain, and is fed slowly overtime.
But then it still makes me wonder why LSD is not affected similarly to psilocybin. God damn it, someone needs to study this.
@pureenergy13 Yeah, I know the method of taking a drug changes how long it lasts, but it doesn't make sense to me that LSD has the same length but psilocybin is reduced GREATLY. When I take mushrooms, the trip lasts probably 4-6 hours. I peak about an hour after taking them. I'd imagine after the peak, that the comedown should still be similar to taking psilocybin orally. But this does not seem to be the case
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Gottaloveacid
Weedbass



Registered: 10/20/14
Posts: 3,421
Loc: Colorado, USA
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Quote:
Achillita said: IMO, that's weird as hell. Other than the onset of the effects being sped up, I can't see why psilocybin would be metabolized faster than if ingested. I know that bill has IVed 4-ACO-DMT, which is nearly exact same as psilocybin and only tripped for around the same duration.
I wonder why are the effects are so sped up though. Maybe it's because of how long it takes the chemical to reach the brain, and is fed slowly overtime.
But then it still makes me wonder why LSD is not affected similarly to psilocybin. God damn it, someone needs to study this.
@pureenergy13 Yeah, I know the method of taking a drug changes how long it lasts, but it doesn't make sense to me that LSD has the same length but psilocybin is reduced GREATLY. When I take mushrooms, the trip lasts probably 4-6 hours. I peak about an hour after taking them. I'd imagine after the peak, that the comedown should still be similar to taking psilocybin orally. But this does not seem to be the case
I wonder if it has something to do with tryptamines in general, but I am not sure, I would have to do more digging.
It would make some sense though as LSD isn't a tryptamine, rather it is a lysergamide.
Here is an anecdote for an example of aMT, a tryptamine that normally has effects orally of 12 hours or so but when IV, this person reported only a 3 hour experience
https://www.erowid.org/experiences/exp.php?ID=20165
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 The greatest story ever told is the story that never ends! wubba lubba dub dubstep
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Bill_Oreilly
ANIMALS (the RAINBOW SERPENT)


Registered: 11/12/11
Posts: 26,370
Loc: Boston
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IV 4-aco-dmt lasted longer than smoked dmt, but way less than eating mmushrooms. Id say I was completely down at the 30-40 minute mark.
it was the weirdest most intense rush of my life. It was NOTHING like a cocaine or heroin rush...this was totally different. It was this "chemically" rush...like if you were to get electrocuted and shot with electrical impulses at the same time. Very peculiar. It hits you almost before you can pull the needle out of your arm.
-------------------- Something there is mysteriously formed, Existing before Heaven and Earth, Silent, still, standing alone, unchanging, All-pervading, unfailing, I do not know its name; I call it tao. If forced to give it a name, I call it Great (ta). Being great, it flows out; Flowing out means far-reaching; Being far-reaching, it is said to return. It's just a shot away..
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