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OfflineCosmicShroom
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Safe to take Syrian Rue and Psylocybes day after taking MDMA?
    #21745845 - 05/31/15 06:59 PM (8 years, 7 months ago)

I was reading reports from people taking Syrian Rue with low MDMA dosage resulting in pleasant experiences. There are reports of people taking too much mdma with the rue as well.

Had some molly last night and was wondering if it would be safe to take the Rue (RiMA) tonight.
From the reports i read  I should be  but I would like a second opinion from knowledgable people.


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OfflineAngel_Above
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21746061 - 05/31/15 07:56 PM (8 years, 7 months ago)

Well I wouldn't EVER suggest an MAOI with mdma. The risk of serotonin syndrome is usually avoided by most because it's essentially, if it happens, pretty much lethal/very damaging.

I mean do you need to take the rue? Chances are you will be safe, but to avoid ignorantly causing someone a hospital visit, I would say better wait.

Though if you wanna be super safe, research the half life, check it with the time you dosed etc n go from there. Personally idk i might ll


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OfflineCosmicShroom
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: Angel_Above]
    #21746121 - 05/31/15 08:12 PM (8 years, 7 months ago)

Thanks for the input, I ate 5 grams of seed at 7pm and will eat 4 grams of mixed cubensis at 8pm, we'll see how it goes, it's my first time adding rue to the mix so tonight with be interesting.:sporedrop:


--------------------
"The eyes are useless if the mind is blind"


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OfflineAngel_Above
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21746147 - 05/31/15 08:17 PM (8 years, 7 months ago)

dude 5 grams of rue, why? that's a hell of a lot lol that's a seriously high dose of rue.

It will impact the trip you can count on that. Be careful okay, check your vitals/temp and enjoy the trip since there's no turning back (not trying to alarm you lol you'll be good just be safe!)

Why did you ask us if you weren't going to take our advice? haha well seeing as you said 8 pm thats prob in 45 mins. I say take it after 45 minutes instead of an hour. Rue makes me sleepy.

Good vibes. That's a huge dose of mushrooms, much more than I'm comfortable with, so I'll do this because "treat others the way you wanna be treated" if it gets tough, just start humming/chanting/holding tones. Like eeeeeeeeee oooooo-ooooh

It really helps you focus and get beyond the mental grasp.

Sending all sorts of love to the PNW for you bud. bon voyage


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Offlinethewanderer25
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: Angel_Above]
    #21746190 - 05/31/15 08:29 PM (8 years, 7 months ago)

:death: dude this just happened a month ago with that one guy ending up in the hospitle dont fuck with the maios bro their lethal things if used wrong. 10 bux says this goes wrong


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OfflineTrippieHunter
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: thewanderer25]
    #21746359 - 05/31/15 09:09 PM (8 years, 7 months ago)

Good vibes brah!! It's too late for any advice so ride it out and have a good trip! Do you have any one with you?


--------------------
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FILM THE POLICE!!! CLICK ME

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Let it go and you will trip into wonderland!


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OfflineAngel_Above
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21746444 - 05/31/15 09:32 PM (8 years, 7 months ago)

OP check your vitals...

Creepy that he chose a skull and cross bones for his thread picture, and refused to take my advice and just went ahead with it.

Hope he's okay


Edited by Angel_Above (05/31/15 09:34 PM)


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OfflineCosmicShroom
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: Angel_Above]
    #21746477 - 05/31/15 09:39 PM (8 years, 7 months ago)

Just to clarify im not taking mdma with the rue, i took the mdma last night and am now high on psilohuasca seperately.
I laughed untrolably at some of these post the positive energy im exeriencing right now is unbelivable though.
I accept the 10$ bet, i bet i will be fine.
I am alone but will be with my lady in an hour or so.
How do I check my vitals?


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Offlinethewanderer25
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21746537 - 05/31/15 09:55 PM (8 years, 7 months ago)

you should be fine actually i thought you were taking MDMA with it and something about amphetamines and MAOIs is bad. plus the skull and cross bones freaked me out but sending good vibes now :thisisgonnabegood:


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OfflineCosmicShroom
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: thewanderer25]
    #21746749 - 05/31/15 10:52 PM (8 years, 7 months ago)

Very week trip so i made a strawberry lemonade with a frozen chunk of 35g fresh shroom tea.
My tolerance is nasty. What can i expect with the rue in my system?


--------------------
"The eyes are useless if the mind is blind"


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OfflineTrippieHunter
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21746782 - 05/31/15 11:05 PM (8 years, 7 months ago)

damn brah you are just determined aren't ya?


--------------------
Just remember keep the camera rolling and
FILM THE POLICE!!! CLICK ME

WHO'S SIDE ARE YOU ON? CLICK ME TOO!

Let it go and you will trip into wonderland!


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Offlinethewanderer25
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: thewanderer25]
    #21752322 - 06/02/15 11:28 AM (8 years, 7 months ago)

I called it he has not been online since then. I hope he is all right
Quote:

thewanderer25 said: 10 bux says this goes wrong


I swear any time somebody uses the skull and cross bones bad shit is to come.


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OfflineTrippieHunter
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: thewanderer25]
    #21755483 - 06/02/15 11:16 PM (8 years, 7 months ago)

Quote:

thewanderer25 said:
I called it he has not been online since then. I hope he is all right
Quote:

thewanderer25 said: 10 bux says this goes wrong


I swear any time somebody uses the skull and cross bones bad shit is to come.





lets hope not.


--------------------
Just remember keep the camera rolling and
FILM THE POLICE!!! CLICK ME

WHO'S SIDE ARE YOU ON? CLICK ME TOO!

Let it go and you will trip into wonderland!


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OfflineCosmicShroom
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: TrippieHunter]
    #21760798 - 06/04/15 09:11 AM (8 years, 7 months ago)

Hello everyone, after the initial mild but pleasant high from the first 4 dry grams I drank a strawberry lemonade containing 35g fresh shroom tea. I experienced and evil sinister delirium because I was hippie flipping. The mdma in my body was reactivated for lack of a better term. At first it was an experience that was pleasant and enjoyable. Hippy flipping is amazing with a low dose of shrooms.
but when i drank the magic strawberry lemonade it become dark and evil I had to tell my girl to take me home because I was afraid I would hurt herm when I got home the delirium continued for a good hour or so, once the mdma from the night before wore off the trip became pleasant and felt a lot more "Nature" like and I saw many patterns of mushrooms everywhere instead of my usual geometrical patterns. It was very interesting but I will never allow the three substances to  .
Gather together in my body again. I experienced no headaches or physical negatives, many people have used doses close to 20mg of mdma with Rue for pleasant experiences. I did feel irritable the next day though I do not know why I usually feel excellent the day after a normal trip.


Edited by CosmicShroom (06/04/15 09:33 AM)


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Offlinetwelvelookslikeu
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21760842 - 06/04/15 09:22 AM (8 years, 7 months ago)

I'm glad there are people out there that dont have a sense of caution that can be are Guinea pigs.


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OfflineCosmicShroom
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21760847 - 06/04/15 09:23 AM (8 years, 7 months ago)

Also I would like to add that Serotonin Syndrome is usually only present with SSRI drugs which Syrian Rue is not.
Remember fellas Syrian Rue is a RiMA not an MAOi.


--------------------
"The eyes are useless if the mind is blind"


Edited by CosmicShroom (06/04/15 09:31 AM)


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OfflineCosmicShroom
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21760860 - 06/04/15 09:27 AM (8 years, 7 months ago)

Lol it's foolish of you to have that perspective because you are assuming I did no research before making the decision I made. Im a bold ass mutherfucking explorer so fuck you and your presumptive ass!
twelvelookslikeu

I also ate cheese and mayo and fish because the diet doesn't apply in the same way to Syrian Rue, dig a little deeper brothers



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Offlinetwelvelookslikeu
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21760881 - 06/04/15 09:33 AM (8 years, 7 months ago)

Your the one who made a thread asking questions :sploosh:


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OfflineCosmicShroom
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: twelvelookslikeu]
    #21760887 - 06/04/15 09:34 AM (8 years, 7 months ago)

It was for a second opinion because it better to be safe than sorry but never the less I knew what I was doing so your commentary is not needed and is indeed a nuisancance to the growth of the community your negativity is not needed.


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Offlinetwelvelookslikeu
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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21760896 - 06/04/15 09:36 AM (8 years, 7 months ago)

My dearest apology


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Re: Safe to take Syrian Rue and Psylocybes day after taking MDMA? [Re: CosmicShroom]
    #21761097 - 06/04/15 10:37 AM (8 years, 7 months ago)

Quote:

CosmicShroom said:
I also ate cheese and mayo and fish because the diet doesn't apply in the same way to Syrian Rue, dig a little deeper brothers




You need to dig a little deeper too. None of those foods are contraindicated with pharmaceutical MAOIs either. It is only aged cheese that is contraindicated.

"Foye's Principles of Medicinal Chemistry" states that those foods that are contraindicated with MAOIs are protein-rich foods that have undergone protein breakdown.

Hypertensive crises with MAOIs have occurred in some patients following ingestion of foods containing large amounts of tyramine or tryptophan. In general, patients taking MAOIs should avoid protein foods that have undergone protein breakdown by aging, fermentation, pickling, smoking, or bacterial contamination.

Foye's Principles of Medicinal Chemistry, Seventh Edition. Thomas L. Lemke, Ph.D., David A. Williams, Ph.D., Victoria F. Roche, Ph.D., S. William Zito, Ph.D. 2013.

Smoked fish and pickled herring has been listed as a restricted food, however an article entitled "MAO Inhibitors: Risks, Benefits, and Lore"* lists those fish products as "unnecessarily restricted."

And mayonnaise is not aged and neither is its vinegar component. The crude vinegar product, rice vinegar, is aged, however rice is not high in protein, so I don't think it would be an issue.

Foods said to be unnecessarily restricted in the "Risks, Benefits, and Lore" article:

avocados; bananas; beef or chicken bouillon; chocolate; fresh and mild cheeses, eg, ricotta, cottage cheese, cream cheese, processed cheese slices; fresh meat, poultry, or fish; meat gravy (fresh); monosodium glutamate; peanuts; properly stored pickled or smoked fish (eg, herring); raspberries; and yeast extracts (except Marmite).

The article lists the following as "absolute restrictions":

• Aged cheeses and meats
• Banana peels
• Broad bean (fava) pods
• Spoiled meats
• Marmite
• Sauerkraut
• Soybean products
• Draft beers


So, until you eat one of those foods with rue, you haven't put anything to the test. Oh and I think if the MAOI diet is violated when on rue, it kicks the rue out of your system (those pharmaceuticals aren't capable of being kicked out of one's system, which is why violating the diet when on them is potentially fatal). That's the impression I got from reading this info on the MAOI, moclobemide, which is a similar to rue (no diet restrictions, unlike some other MAOIs): http://www.shroomery.org/forums/showflat.php/Number/21464326


CosmicShroom said he was going to take the rue and mushrooms a day after the MDMA, so why are people worried about a possible interaction? Two substances can't interact if they're not in the person's system at the same time as each other. God damn, what's wrong with you people? And as CosmicShroom said, he's read reports where people actually took Syrian rue with MDMA. I too had seen a report of this (https://www.erowid.org/experiences/exp.php?ID=24742). It wouldn't surprise me if taking MDMA with Syrian rue was safe, given the following info, which indicates that MAOIs are not as restrictive as people have been lead to believe:


#1 We have found all antidepressants that do not involve significant serotonin reuptake inhibition (e.g., bupropion, trazodone, and tricyclics other than clomipramine) can be safely administered with MAOIs. Combination therapy is worth considering because it may be effective when other approaches have failed.

Cole J, Bodkin A. MAO inhibitors: An option worth trying in treatment-resistant cases. Current Psychiatry, Vol. 1, No. 6, June 2002


#2 Two examples of MAOIs combined with amphetamines:

Im not taking Nardil but I'm taking 80mg Parnate. Recent studies show that if you're MAOI resistant stimulants can help. I'm taking 70 mg of Vyvanse and Ritalin (not Adderal). My blood pressure is normal and the MAOI started working. Some people go as high as 120mg with stimulants. Just watch your blood pressure. Of course the higher you go the dietary restrictions become more pertinent.

7/2/2014  MRDIGBY  http://www.socialanxietysupport.com/forum/1073591857-post542.html


Stimulant + MAOI journal



*MAO Inhibtors: Risks, benefits, and lore. Wimbiscus, Molly MD; Olga Kostenk, MD; Donald Malone, MD. Cleveland Clinic Journal of Medicine. vol. 77, no. 12, Dec 2010


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