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Salomon
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drug burritos and gaba spins. which way does the world turn to the drunk?
#21285689 - 02/16/15 10:04 PM (9 years, 3 months ago) |
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so i had an idea today
and it totally worked.
here i am with a bag of phenibut and i want it in mah belly. so i grabbed some tortilla warp's and started making egg roll sized burritos of a few grams in each, let them dry in a little spring roll size and swallow em like a condom full of cocaine in mexico.
great idea, love it.
i ate like 5 of those things so uma collective 15 ish grams over the past few hours... which led me to wonder something....scientific.
so scientific that it involves a poll!
so to you GABA users, when you consume a GABA-a drug, and you feel spiny, and your vision gets fucked does your vision spin clockwise or counter clockwise?
and when you consume GABA-b drug, and you feel spiny, and your vision gets fucked does your vision spin clockwise or counter clockwise?
don't know the difference? here's a quick wiki reference. there IS a bit of cross reference between the two, aa well as sub sites in play, but the basic definitive division exists
https://en.wikipedia.org/wiki/GABAA_receptor
^Quote:
Examples
Agonist: GABA, gaboxadol, isoguvacine, muscimol, progabide, piperidine-4-sulfonic acid (partial agonist). Antagonists: bicuculline, gabazine. Positive allosteric modulators: barbiturates, benzodiazepines, carisoprodol, thienodiazepines, ethanol (alcohol), etomidate, glutethimide, kavalactones,[23] meprobamate, methaqualone, neuroactive steroids,[24] niacin/niacinamide,[25] nonbenzodiazepines, propofol, stiripentol,[26] theanine, valerenic acid, volatile/inhaled anesthetics, and lanthanum.[27] Negative allosteric modulators: flumazenil, Ro15-4513, sarmazenil, and zinc.[28] Non-competitive channel blockers: cicutoxin, oenanthotoxin, pentylenetetrazol, picrotoxin, thujone, and lindane
https://en.wikipedia.org/wiki/GABAB_receptor
^ Quote:
Agonist
GABA Baclofen is a GABA analogue which acts as a selective agonist of GABAB receptors, and is used as a muscle relaxant. However, it can aggravate absence seizures, and so is not used in epilepsy. gamma-Hydroxybutyrate (GHB) Phenibut 3-Aminopropylphosphinic acid Lesogaberan SKF-97541: 3-Aminopropyl(methyl)phosphinic acid, 10x more potent than baclofen as GABAB agonist, but also GABAC antagonist CGP-44532
as for myself it seems that alpha spin to the right and beta spin to the left , so i decided to do a half assed study on the subject
questions, statements, comments, intelligent discussion on the subject is appreciated. and no, the spins are not simply the result of disturbances in the inner ear, although that is a contributing factor. also recoginize that while i post this, i'm balls deep in falling asleep from the drug combinatoions ive been ingesting, spare me the bitching about any gramatical or other logic mistakes i may have made in this pl0x k thx
so here's the poll:
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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jewunit
Brutal!


Registered: 01/11/07
Posts: 34,264
Loc: Ohio
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: Salomon]
#21285916 - 02/16/15 11:04 PM (9 years, 3 months ago) |
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Yeah if I have the spins I'm certainly not taking note of which way the world is turning.
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OhMrJohnson
Modern Day Alchemist

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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: Salomon]
#21285937 - 02/16/15 11:08 PM (9 years, 3 months ago) |
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I really creep myself out sometimes
I had this distinct sensation earlier in the day that I would see you posting here in the Pub within a few hours
And what do we know, here you are
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Diminish the sub-principle and leave its toxic trace.. Once and for all!
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LuSiD enthusiast
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: jewunit]
#21285940 - 02/16/15 11:09 PM (9 years, 3 months ago) |
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Mine spins clockwise and i hear if you live south of the equator it goes counterclockwise.
But seriously when i get them they very vividly swing up and to the right, so yeah clockwise, but i've never had it make a full rotation before, that would just be crazy.
-------------------- I'm addicted to coke, weed, booze, ludes and speed. Not LSD, you can't get addicted to LSD, it was built by scientists. I ain't got no demons that gonna get woke. In erowid we trust. Just take your damn pills and don't ask any questions, you'll be fine.
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Salomon
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: OhMrJohnson]
#21285964 - 02/16/15 11:16 PM (9 years, 3 months ago) |
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mayhaps i'm the only one whom is preoccupied with asking "why" the room is spinning in a certian direction while shitfaced
i suppose it should have occurred to me that most people wouldn't care, and are probably busy puking and arent thinking about science
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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KingKnowledge
Around



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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: Salomon]
#21285971 - 02/16/15 11:18 PM (9 years, 3 months ago) |
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Aren't GABA-A pre-synaptic and GABA-B post synaptic? I have a hard time believing activation on one side or the other of a neuronal synapse would cause a different spin. What would be the science behind that in your opinion OP?
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LuSiD enthusiast
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: KingKnowledge]
#21286010 - 02/16/15 11:36 PM (9 years, 3 months ago) |
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Quote:
KingKnowledge said: Aren't GABA-A pre-synaptic and GABA-B post synaptic? I have a hard time believing activation on one side or the other of a neuronal synapse would cause a different spin. What would be the science behind that in your opinion OP?
Your overcomplicating it. It has more to do with your relative location to the equator. Kinda like toilets flushing.
-------------------- I'm addicted to coke, weed, booze, ludes and speed. Not LSD, you can't get addicted to LSD, it was built by scientists. I ain't got no demons that gonna get woke. In erowid we trust. Just take your damn pills and don't ask any questions, you'll be fine.
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Salomon
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: KingKnowledge]
#21286017 - 02/16/15 11:37 PM (9 years, 3 months ago) |
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well both are relying directly on the production of GABA through the intermediate release of gultimate, right?
so depending on the function of glulimatic acid being used in the metabolism of these particular drugs being ingested, that would respectively determine which channels are being allowed to function, through chlorine, calcium, or potassium isotope ion channels
so i was thinking that the particular ionization of channels would change the ocular response to the metabolism; IE the difference is which channel is being more prominently used would change what is seen.
I'm not exactly a neurologist, so my understanding of neurological biochemistry is flawed, I'll openly admit.
but since there is a visual element to these metabolic processes, i thought surely there would be a coorelation, aside from the ones that also have NDMA activity.
i coulda been wrong, but i'm genuinely curious.
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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Salomon
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: LuSiD enthusiast]
#21286018 - 02/16/15 11:38 PM (9 years, 3 months ago) |
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Quote:
LuSiD enthusiast said:
Quote:
KingKnowledge said: Aren't GABA-A pre-synaptic and GABA-B post synaptic? I have a hard time believing activation on one side or the other of a neuronal synapse would cause a different spin. What would be the science behind that in your opinion OP?
Your overcomplicating it. It has more to do with your relative location to the equator. Kinda like toilets flushing.
really?
how can you be sure?
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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LuSiD enthusiast
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: Salomon]
#21286027 - 02/16/15 11:41 PM (9 years, 3 months ago) |
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Quote:
Salomon said:
Quote:
LuSiD enthusiast said:
Quote:
KingKnowledge said: Aren't GABA-A pre-synaptic and GABA-B post synaptic? I have a hard time believing activation on one side or the other of a neuronal synapse would cause a different spin. What would be the science behind that in your opinion OP?
Your overcomplicating it. It has more to do with your relative location to the equator. Kinda like toilets flushing.
really?
how can you be sure?
Just trust me on this one dude, I've done lots of research.
-------------------- I'm addicted to coke, weed, booze, ludes and speed. Not LSD, you can't get addicted to LSD, it was built by scientists. I ain't got no demons that gonna get woke. In erowid we trust. Just take your damn pills and don't ask any questions, you'll be fine.
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Salomon
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: LuSiD enthusiast] 1
#21286065 - 02/16/15 11:51 PM (9 years, 3 months ago) |
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so if you were drunk while flying in a plane from a hemisphere where toilets flush counter clockwise to a hemisphere where toilets flush clockwise, your drunk vision would reverse?
that doesn't really seem to compute considering yor brain is a bit more complex than a simple rotational spin of a toilet flush.
so like if you flush a toilet on a plane that drains counter clockwise to a hemisphere where toilets flush clockwise, your toilet would suddenly reverse ?
what if you were drunk at the same time as flushing a toilet?

i,,,,,,,,,,,, i don't believe you
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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jewunit
Brutal!


Registered: 01/11/07
Posts: 34,264
Loc: Ohio
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: Salomon]
#21286110 - 02/17/15 12:05 AM (9 years, 3 months ago) |
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Quote:
Salomon said: mayhaps i'm the only one whom is preoccupied with asking "why" the room is spinning in a certian direction while shitfaced
i suppose it should have occurred to me that most people wouldn't care, and are probably busy puking and arent thinking about science
Which one makes you more of an egomaniac?
Which hemisphere you're in doesn't effect which direction a toilet flushes is, btw.
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Salomon
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: jewunit]
#21286133 - 02/17/15 12:13 AM (9 years, 3 months ago) |
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does it make me an egomaniac to ask "why"?
i don't see your point.
i'm just trying to figure out this phenomena that happens to be centralized to my brain while i take drugs. knowing others experience the same, or similar things as me, i thought it would be neat to ask others about their experiences and get more info on the subject.
maybe my post insulted you in some way.. that was not my intent.
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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jewunit
Brutal!


Registered: 01/11/07
Posts: 34,264
Loc: Ohio
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: Salomon]
#21286144 - 02/17/15 12:18 AM (9 years, 3 months ago) |
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I'm not insulted nor do I think that was your intent. The whole "maybe I'm the only one who thinks about science when I'm wasted" just makes you sound full of yourself, especially since only one person so far responded saying otherwise.
Maybe it's just a dumb question.
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Hobozen


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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: jewunit]
#21286159 - 02/17/15 12:23 AM (9 years, 3 months ago) |
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that's not exactly what he said, seems a bit disingenuous to quote him incorrectly. plus, i'm pretty sure he was being humorous.
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Salomon
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: jewunit]
#21286162 - 02/17/15 12:24 AM (9 years, 3 months ago) |
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sorry about that, my phrasing was inappropriate i see, how it came off in the manor of an ego driven thought process. i suppose that was rude of me
good sir, i am heavily intoxicated and i obviously did nit wait long enough for a more varied reply, i appreciate your contribution to this thread
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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jewunit
Brutal!


Registered: 01/11/07
Posts: 34,264
Loc: Ohio
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: Hobozen]
#21286176 - 02/17/15 12:28 AM (9 years, 3 months ago) |
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I wasn't trying to directly quote him. I guess if we were talking in person it would be more of a mocking impersonation. Tough to get across through text I suppose.
OP:You don't have to apologize for being rude. As I said, I don't think that was your intent, nor did I take offense to what you said. I did take it as a serious response, so whatever. Maybe it wasn't, that'd cool.
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LuSiD enthusiast
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: Salomon]
#21287418 - 02/17/15 11:07 AM (9 years, 2 months ago) |
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Quote:
Salomon said: so if you were drunk while flying in a plane from a hemisphere where toilets flush counter clockwise to a hemisphere where toilets flush clockwise, your drunk vision would reverse?
that doesn't really seem to compute considering yor brain is a bit more complex than a simple rotational spin of a toilet flush.
so like if you flush a toilet on a plane that drains counter clockwise to a hemisphere where toilets flush clockwise, your toilet would suddenly reverse ?
what if you were drunk at the same time as flushing a toilet?

i,,,,,,,,,,,, i don't believe you
What if you looked at a toilet spinning in the opposite direction of your spins?
-------------------- I'm addicted to coke, weed, booze, ludes and speed. Not LSD, you can't get addicted to LSD, it was built by scientists. I ain't got no demons that gonna get woke. In erowid we trust. Just take your damn pills and don't ask any questions, you'll be fine.
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goldcaphunter
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Re: drug burritos and gaba spins. which way does the world turn to the drunk? [Re: LuSiD enthusiast]
#24010534 - 01/14/17 07:00 PM (7 years, 4 months ago) |
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Year old bump I've only ever gotten the spins from alcohol and I've taken massive doses of benzos with no spins. When I get em from alcohol I've honestly never really paid attention to the rotation, I just vomit them away  Also I love the list of gaba type drugs in the op, maybe more scientific answers could be found in odd? I can't be the only one thinking this is bump worthy.
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  The picture to the far left is a reminder to our users to stay safe and healthy, that's my third open heart surgery due to over use of amps. Stay safe kiddos
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