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OfflineImobiletoe
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Registered: 10/15/03
Posts: 69
Loc: Seattle, WA
Last seen: 12 years, 1 month
psilocybin to psilocin.
    #2069361 - 11/04/03 04:01 AM (13 years, 7 months ago)

I have been told that once psilocybin enters the body it metabolizes into psilocin. Is this true? reminds me of how someone told me that heroin actually turns into morophine once in the body.


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InvisibleJohn
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Registered: 08/08/03
Posts: 7,026
Loc: Vancouver, B.C.
Re: psilocybin to psilocin. [Re: Imobiletoe]
    #2069365 - 11/04/03 04:04 AM (13 years, 7 months ago)

It's never been proven but is highly suspected, I would say yes it does, here's an excerpt from tihkal...

On the topic of psilocybin and psilocin, one of the most frequent questions I am asked is, "Isn't it true that psilocybin is immediately converted to psilocin in the blood stream, and so the two chemicals are in essence identical, molecule for molecule?" At this moment I always suppress a brief sense of mental fragmentation, with the automatic reply, "Where is the evidence that psilocybin is converted to psilocin in man?" If it exists, I certainly do not know of it. This clears my conscience. I really do not know the answer. But I have a tremendously strong suspicion that it really does. Any such ester, be it the phosphate, the sulfate, or the acetate, would all be easily split to the archetypal indolol by the ubiquitous esterases in the body. I do indeed believe, in my inner heart, that they all act upon the brain as the same end product, psilocin.


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There's a thin line between sanity and insanity... and I just snorted it.


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Offlinegnrm23
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Registered: 08/30/99
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Re: psilocybin to psilocin. [Re: John]
    #2069550 - 11/04/03 07:15 AM (13 years, 7 months ago)

re: heroin... heroin is diacetylmorphine; this molecule permeates the blood-brain-barrier much more easily than does the morphine molecule... once inside the brain, heroin is de-acetylated into morphine...


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old enough to know better
not old enough to care


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OfflineSeussA
Error: divide byzero

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Registered: 04/27/01
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Loc: Caribbean
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Re: psilocybin to psilocin. [Re: gnrm23]
    #2069591 - 11/04/03 08:30 AM (13 years, 7 months ago)

As usual, both jtryptamine and gnrm23 are correct. 

Heroin was actually used for a very short while to treat morphine addiction.  :grin:


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Just another spore in the wind.


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Offlinegnrm23
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Re: psilocybin to psilocin. [Re: Seuss]
    #2069958 - 11/04/03 12:05 PM (13 years, 7 months ago)

& ya could purchase it right outa the sears catalog...


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old enough to know better
not old enough to care


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