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InvisibleDOBAS
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LSA and Niacin
    #20409563 - 08/12/14 04:28 PM (9 years, 6 months ago)

When should I take the Niacin? I have been reading that it is a good option to counter the  vasoconstriction.

With my dose?
Hours before?

Thanks


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Offline1314697
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Re: LSA and Niacin [Re: DOBAS]
    #20409838 - 08/12/14 05:36 PM (9 years, 6 months ago)

I honestly wouldn't take niacin. I've never actually heard of someone having a bad time with lsa because of vasco-contriction.

Sure there could be some leg cramps but a CWE and weed has no cramps IME. You'll probably be fine without the niacin but I guess take it the same time as the lsa.


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Invisiblerefried

Registered: 06/14/13
Posts: 3,675
Re: LSA and Niacin [Re: 1314697]
    #20410642 - 08/12/14 08:50 PM (9 years, 6 months ago)

I once took a huge amount of niacin because I heard it would help me pass a drug test.  Horrible reaction to it, one of the worst things I've experienced substance-wise.  I also don't recommend swallowing matchheads and drinking gatorade with a capful of bleach in it.  That will not work.  The red gatorade turns clear as water and your stomach will be totally fucked.

This was about age 17 and before the internet...  :laugh:

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Invisible4HO-DMT
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Re: LSA and Niacin [Re: DOBAS]
    #20411450 - 08/13/14 12:55 AM (9 years, 6 months ago)

Have you taken niacin before, without psychedelics? It's a trip in it self. It's harmless but feels like an allergic reaction to most. Could be interesting while tripping. I would suggest taking it when you feel vasoconstriction. It acts rather quickly. Good luck.

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Offlinejsncrs
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Re: LSA and Niacin [Re: refried]
    #20411460 - 08/13/14 12:58 AM (9 years, 6 months ago)

Quote:

refried said:
I also don't recommend swallowing matchheads and drinking gatorade with a capful of bleach in it.  That will not work.  The red gatorade turns clear as water and your stomach will be totally fucked.

This was about age 17 and before the internet...  :laugh:




WTF man

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InvisibleDOBAS
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Re: LSA and Niacin [Re: 4HO-DMT]
    #20412001 - 08/13/14 07:52 AM (9 years, 6 months ago)

Quote:

4HO-DMT said:
Have you taken niacin before, without psychedelics? It's a trip in it self. It's harmless but feels like an allergic reaction to most. Could be interesting while tripping. I would suggest taking it when you feel vasoconstriction. It acts rather quickly. Good luck.



Nope I've never taken Niacin before. Well I've had red bulls which contain Niacin.

I took a pre workout twice and they contain Niacin.  Both times I was itching like a motherfucker and felt like I had a rash.


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Invisible4HO-DMT
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Re: LSA and Niacin [Re: DOBAS]
    #20415741 - 08/13/14 11:37 PM (9 years, 6 months ago)

Quote:

DOBAS said:
...I took a pre workout twice and they contain Niacin.  Both times I was itching like a motherfucker and felt like I had a rash...




That would be niacin. You will likely have a similar reaction while tripping. It sure dilates the blood vessels though. Many fungi naturally contain niacin.

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Offlinethedream
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Re: LSA and Niacin [Re: 4HO-DMT]
    #20416987 - 08/14/14 09:01 AM (9 years, 6 months ago)

IMO I would drop the niacin as there are better vasodilators available like L-arginine that do not have the "flush" that niacin evokes in many individuals. The most notable vasoconstriction for me was in my lungs. Just have some dark chocolate on hand and a few bong rips will get you back in action. My experience with LSA was extremely lacking but I hope it works out for you.

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OfflineLogicaL ChaosM
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Re: LSA and Niacin [Re: thedream]
    #20417278 - 08/14/14 10:16 AM (9 years, 6 months ago)

I need some clarity on this subject.

So when u guys say "LSA", i assume u mean a cold water extraction from  Morning Glory seeds or HBWR seeds or Oliliqui purhaps.

I was under the assumution that pure LSA, i.e. Extractted alkoloids from the seeds listed above did not have physical side effects aand that the vasconstriction side effect is from the toxins in the seed husk.....

This mystery needs some illumination.

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Offlines240779
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Re: LSA and Niacin [Re: LogicaL Chaos]
    #20417450 - 08/14/14 11:09 AM (9 years, 6 months ago)

Quote:

LogicaL Chaos said:
I was under the assumution that pure LSA, i.e. Extractted alkoloids from the seeds listed above did not have physical side effects aand that the vasconstriction side effect is from the toxins in the seed husk.....




There are about a dozen ergot alkaloids in morning glory seeds.[1] The total quantity varies by species. Ergot is infamous for causing such intense vasoconstriction that people and animals incur gangrene. Luckily, the sub-class of alkaloids thought to be responsible for gangrene is absent from all species of morning glory seeds.[2] However, other ergot alkaloids still cause vasoconstriction.[3] LAA is the only desirable chemical in morning glory seeds.[4]

The idea that the seed husks contain toxins is a rumor that circulates. A similar rumor is that morning glory seeds contain cyanogenic glycosides or cyanide. Sometimes people say the cyanogenic glycosides are in the husks. Two items below that address these claims:

NOTE: All of the references below can be found in my morning glory seed info archive: http://www.shroomery.org/forums/showflat.php/Number/19595277

NOTE: The morning glory seeds that contain ergot alkaloids contain these alkaloids because they're infected with ergot species. Note that it is a permanent infection, unlike that of the grasses that ergot infects. There is a folder in my archive that has all the info on this.

--
There is nothing in the seed coat that makes you sick. That is a myth. The sickness is caused by glycosides found inside the seed. I've eaten seeds scraped and not scraped and there is no difference what-so-ever in the degree of sickness produced.

26-03-2004, morninggloryseed, http://www.bluelight.org/vb/threads/123944-LSA-s-Subthread-Extraction-of-LSA-s?p=1779004&viewfull=1#post1779004


See Eckart Eich's commentary on cyanogenic glycosides on pages 274–275 of his book: Solanaceae and Convolvulaceae: Secondary Metabolites: Biosynthesis, Chemotaxonomy, Biological and Economics Significance (a Handbook) (2008)

"Thus, it may be concluded that cyanogenic glycosides are no frequent constituents in the family Convolvulaceae."

NOTE: Convolvulaceae means morning glory.
--

#1 Example of chemical profile of morning glory seeds:



Source: Chao JM, DerMarderosian AH (1973) Ergoline alkaloidal constituents of Hawaiian baby wood rose, Argyreia nervosa (Burm. f.) Bojer. J Pharm Sci 62:588–591

NOTE: More chemical analyses in my archive.


#2 This sub-class is the ergopeptines. See pages 228-229 of Eckart Eich's book, referenced above; and pages 249-250 suggest that it is this sub-class that causes the gangrene occurences.


#3 Vasoconstriction evidence for ergotamine, ergometrine, dihydroergotamine, and LSD-25. See pages 774-775.

Stoll, A. & Hofmann, A. 1965. The Ergot Alkaloids. Located in R.H.F. Manske (ed.), The Alkaloids, Vol. VIII, Academic Press, New York, Chap. 21

Vasoconstriction evidence for LAA:

Oliver, J.W., L.K. Abney, J.R. Strickland and R.D. Linnabary. 1993. Vasoconstriction in bovine vasculature induced by the tall fescue alkaloid lysergamide. Animal Science Journal 71;2708–2713


#4 What chemical(s) in morning glory seeds are responsible for their effects?

NOTE: lysergamide is a synonym for lysergic acid amide.

Edited by s240779 (08/14/14 03:51 PM)

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OfflineObservatory
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Re: LSA and Niacin [Re: s240779]
    #20418116 - 08/14/14 02:18 PM (9 years, 6 months ago)

Anybody here tried niacin while tripping? I've heard rumors that the stuff can cancel a trip, would be curious to know


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OfflineLogicaL ChaosM
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Re: LSA and Niacin [Re: s240779]
    #20418327 - 08/14/14 03:10 PM (9 years, 6 months ago)

I have to disagree.

This has to be toxins in the seed husk. Why else would you do a non-polar Petrolum ether/Naptha wash before doing a polar extraction?


And from personal experience, just days ago, i ate some morning glory that had been washed with Naptha, and the narcatic effect and some psychedelic was pretty strong, the feeling of leg cramps and sore stomach stomach was minimal.


And Ive had the "fish-eye vision" in the  past, but this recent naptha-washed MG powder had no such side effect aferwords.

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OfflineMitchyDee
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Registered: 08/22/13
Posts: 137
Loc: Washington State
Last seen: 5 years, 5 months
Re: LSA and Niacin [Re: DOBAS]
    #20418479 - 08/14/14 03:47 PM (9 years, 6 months ago)

Quote:

DOBAS said:
Nope I've never taken Niacin before. Well I've had red bulls which contain Niacin.

I took a pre workout twice and they contain Niacin.  Both times I was itching like a motherfucker and felt like I had a rash.



The itching feeling from pre workout supplements is most likely from beta alanine, a substance in most preworkout supps. I am a weightlifter and cannot stand the itchy, tingling feeling.

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