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OfflineEvilGir
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New Psychedelics N,N-Dimheptanetryptamine
    #2004479 - 10/13/03 05:02 AM (13 years, 8 months ago)

Well I have noticed mosted Tryptamine based psychedelics usualy are based on a ethyl or methyl group Like N,N-dimethyltryptamine why isnt there any compounds with an octane group or heptane. So we could then have something like N,N-Diheptanetryptamine.


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OfflineEvilGir
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Re: New Psychedelics N,N-Dimheptanetryptamine [Re: EvilGir]
    #2004514 - 10/13/03 05:59 AM (13 years, 8 months ago)

Ok then so where as N,N-dimethyltryptamine has two CH3 groups at the nitrogen position we could just simply add a CH3CH2CH2CH2CH2CH2CH3 group. Here is a list of possibilities :

CH4 Methane
CH3CH3 Ethane
CH3CH2CH3 Propane ect.

So alot more could be added to make new compounds.


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Offlinegnrm23
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Re: New Psychedelics N,N-Dimheptanetryptamine [Re: EvilGir]
    #2004538 - 10/13/03 06:36 AM (13 years, 8 months ago)

you should contact dr shulgin...
:wink:


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Offlinedjd586
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Re: New Psychedelics N,N-Dimheptanetryptamine [Re: gnrm23]
    #2004866 - 10/13/03 12:06 PM (13 years, 8 months ago)

Here's my thinking. The chemical structure of tryptamine is the functional component of the drug. As long as you keep the basic functional structure you should be able to come up with different variations like you have mentioned and still have the compund be active.

Is it your thinking that certain tryptamine molecules can be converted into gas form?


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OfflineInfrared
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Re: New Psychedelics N,N-Dimheptanetryptamine [Re: EvilGir]
    #2004959 - 10/13/03 12:49 PM (13 years, 8 months ago)

aliphatic alkyl groups
M is for methyl
E is for ethyl
P is for propyl
IP is for isopropyl
B is for butyl
IB is for isobutyl
SB is for sec-butyl
TB is for tert-butyl
A is for amyl
AL is for allyl
H is for hexyl

groups with hetero-atoms
HO is for hydroxy
MeO is for methoxy
MeS is for methylthio
MDO is for methylenedioxy


heres a list of different groups, just because you can technically make it, doesnt mean that it will be active. my suggestion, if your really that interested would be to make them and test them yourself.



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OfflineMetaShroom
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Re: New Psychedelics N,N-Dimheptanetryptamine [Re: Infrared]
    #2005001 - 10/13/03 01:10 PM (13 years, 8 months ago)

IIRC the longer the chains the lower the activity


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OfflineToxicManM
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Re: New Psychedelics N,N-Dimheptanetryptamine [Re: EvilGir]
    #2006861 - 10/14/03 12:20 AM (13 years, 8 months ago)

You should go read TIHKAL, by Alexander Shulgin.

He has already done this research. Those chemicals aren't produced because they'er not active (or, if they are active, the dose is so high that there would be other problems).


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OfflineEvilGir
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Re: New Psychedelics N,N-Dimheptanetryptamine [Re: ToxicMan]
    #2007681 - 10/14/03 07:54 AM (13 years, 8 months ago)

Well my ideas and question was basicaly as to why certain subsitutions have not been preformed on the tryptmaine skelaton.
I was thinking even diffrent elements could be used so a CH3 group could be replaced with a Br or something so we could then have



4,bromo--N,N-dimethyltryptamine

And yes my postioin number is probably wrong but it should give you an idea what can be done.

"IIRC the longer the chains the lower the activity "

Maybe but it dosent mean other subsitution wont work and it would probably also depend on which position on the skeleton it was placed.

As for TIHKAL and PIHKAL I think they are great books but still theres not enough info in there for me I need more data. If only Shulgin still did lectures.


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Offlinegnrm23
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Re: New Psychedelics N,N-Dimheptanetryptamine [Re: EvilGir]
    #2007725 - 10/14/03 08:46 AM (13 years, 8 months ago)

shulgin has stated that 5-Br-DMT has been found in a pacific sponge...
there is research still being done on these various compounds (including s.a.r.) by some of his younger colleagues, but much of the research results must be gleaned from reading _current_ periodicals in the field (j.med.chem., heterocycle, j.nat.prod, lloydia, etc,etc... might require some research at your local uni library, dontchhaknow...)


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