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 plambe
Trader
Registered: 08/06/08
Posts: 1,071
Last seen: 7 years, 10 months
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 Re: Biohacking  [Re: psi]
#19740706 - 03/24/14 12:29 PM (9 years, 2 months ago) |
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Quote:
psi said:
Engineering yeasts to make illegal drugs
What sorts of drugs are you talking about?
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 Barbiturate Research Division
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 bryguy27007
Cosmonaut
Registered: 01/26/08
Posts: 10,512
Loc: 
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Quote:
teamkiller said:
uh how about i just drink coffee? that seems to give all the benefits of everything you mentioned.
less glib though, whats the point of being a peak performance human? where is the benefit? you don't have to be at your peak to make money, learn, fuck or have fun.
No, you don't. But you will do all of those things better if you are at your peak.
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teamkiller 
ghetto drama whore
Registered: 06/06/11
Posts: 8,803
Last seen: 1 month, 3 hours
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whats the benefit of doing something better?
are games more fun if you win?
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bryguy27007
Cosmonaut
Registered: 01/26/08
Posts: 10,512
Loc:
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Quote:
teamkiller said:
whats the benefit of doing something better?
are games more fun if you win?
If you're satisfied with where you're at then that's great. I have this insatiable drive to be the best that I can be. Doing things to completion is very satisfying. Doing things to completion and doing them incredibly well, above and beyond what you previously thought you were capable of, is infinitely more satisfying.
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Moonshoe
Blue Mantis
Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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Coffee is actually a huge part of Dave asprey"s biohacking diet. He recommends drinking "bulletproof coffee" which is organic coffee with grassfed butter and Mct oil or coconut oil added instead of cream and sugar. This makes the coffee very healthy and gives you a long lasting energy lift instead of a quick rush followed by a crash.
I personally believe organic white tea, Yerba mate or raw cacao are better biohacking drinks than coffee but I love coffee and when I drink it I make it bulletproof by adding coconut oil and grassfed butter or ghee (clarified butter).
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Everything I post is fiction.
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teamkiller
ghetto drama whore
Registered: 06/06/11
Posts: 8,803
Last seen: 1 month, 3 hours
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 the bullet proof coffee is pure marketing baloney m8
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Moonshoe
Blue Mantis
Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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Well I don't recommend ordering anything from Dave asprey . Just make your own at home . Just use your regular organic coffee and add a teaspoon or a tablespoon of coconut oil and a teaspoon of grass fed butter or ghee. The nutritional logic is completely sound.
It makes your coffee into a long lasting nutritional energy source that is high in calories and healthy fats which as I said in the OP is a big part of the biohacking diet.
You don't need to buy any special products just make your own at home and enjoy the benefits and flavour.
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Everything I post is fiction.
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Moonshoe
Blue Mantis
Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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It's cool how we both have mantis avatars .
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Everything I post is fiction.
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plambe
Trader
Registered: 08/06/08
Posts: 1,071
Last seen: 7 years, 10 months
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Quote:
Moonshoe said:
It's cool how we both have mantis avatars .
lol I was getting confused at first wondering who's who cause you both have mantis avatars.
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Barbiturate Research Division
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Moonshoe
Blue Mantis
Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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You said "you don't have to be at your peak to make money, learn, fck or have fun, which is true, but if you are a your peak you will make more money, learn faster and better, fuck better and more often and have much more fun.
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Everything I post is fiction.
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Ellis Dee
Archangel
Registered: 06/29/01
Posts: 13,104
Loc: Fire in the sky
Last seen: 4 years, 2 months
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It sounds a lot like trying to live a healthy lifestyle combined with supplements. When I read biohacking I was thinking of DNA stuff. What came to mind was designer children with enhanced strength, intelligence, and immunity or something along those lines.
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"If the foundations be destroyed, what can the righteous do."-King Solomon
And there was war in heaven: Michael and his angels fought against the dragon; and the dragon fought and his angels,
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Alan Rockefeller
Mycologist
Registered: 03/10/07
Posts: 47,919
Last seen: 21 hours, 47 minutes
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Quote:
Moonshoe said:
I can add a lot more biohacking tips, tools and Techniques to this thread and elaborate on the theory of biohacking if people are interested and it looks like they are !
This is not biohacking. Biohacking involves making cool things in a lab, often DIY biohackers use a spare room in a house as a lab.
Your idea if biohacking is just exercise and taking drugs and eating food.
I go to regular biohacking meetings, here is an excerpt from the minutes of the last meeting - This is what we are planning on doing.
3D pattern formation toolkit
Engineer plant cells to differentiate under (green?) light sensitive promoter
Extrude protein based biomaterials (wool, silk, spider silk, etc.) using injectosome
Engineer bacteria/yeast to break down gluten (already done? can be improved?)
“YoVivo” resveratrol producing yogurt. Metabolic pathway starts by synthesizing p-courmaric acid -> can make *lots* of stuff from there, not just resveratrol!
IR fluorescence proteins
iGEM-compatible golden braid assembly
Molecular biology techniques to evolve and select specific functions of interest (site directed mutagenesis, MAGE, SELEX, phage display, make and screen fosmid libraries for novel enzymes, …)
Build hardware/robot to automatically run these protocols
Make cheaper versions of expensive automation bots (e.g. flashgel)
Growing things on a 3D printed surface with technology similar to peachy printer (e.g. using a photoactivatable gel, that traps cells?)
Grow cellulose film using Acetobacter xylinum; slowly wind it up on a spool. Engineer the bacteria to incorporate pigments.
Making vegan ‘cheese;’ express casein protein in yeast. Marc Juul is interested in working on this.
Design an open-source, antibiotic-free plasmid for DIYbio - see indieBB campaign. Genspace has dibs on this, but might be able to collaborate.
Get CRISPR-Cas9 system to work in E. coli and/or yeast. Probably tons of “professional” competition on this. More protocol optimization problem, than actual synbio problem.
RNA based genetic circuitry, using riboswitches etc. See journal club video
Use light-directed bacteria to deposit electrical or optical circuits - self assembling mega organic logic machines
Sensor to detect DNA damage - use to look at water quality
Command other bacteria to produce proteins of interest to ensure it is retained in ecosystem and not selected out by evolution
Structural colors - with or without DNA origami
Biosphere with biosensors to detect something going wrong - funding from NASA/SpaceGambit
Degrade diuretic component in coffee/beer
Caffeine breakdown deficiency
Program to design metabolic pathways to produce any desired biochemical
Light switchable tRNA / nucleotides
Make genetically engineered strawberries that taste like mango, size of a peach, bioluminesce when ripe
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plambe
Trader
Registered: 08/06/08
Posts: 1,071
Last seen: 7 years, 10 months
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Quote:
Your idea if biohacking is just exercise and taking drugs and eating food.
 can't argue here
Quote:
Get CRISPR-Cas9 system to work in E. coli and/or yeast.
Yeah thats definitely cool. I cloned a nuclease defective Cas9 which I'm going to cut out of the vector in the next few days and ligate it to plant stress hormone receptors so I can deliver shit wherever I want when I want in the nucleus.
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Barbiturate Research Division
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teamkiller
ghetto drama whore
Registered: 06/06/11
Posts: 8,803
Last seen: 1 month, 3 hours
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Re: Biohacking [Re: plambe] 1
#19741102 - 03/24/14 01:52 PM (9 years, 2 months ago) |
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alan i want to talk about that but first i gotta say the mantis is my spirit animal
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Apostle
Philanthropist
Registered: 12/12/09
Posts: 31,501
Loc: FL
Last seen: 4 months, 27 days
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biohackers?
do you guys have an official mask yet?
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plambe
Trader
Registered: 08/06/08
Posts: 1,071
Last seen: 7 years, 10 months
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Re: Biohacking [Re: Apostle]
#19741136 - 03/24/14 02:02 PM (9 years, 2 months ago) |
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As Alan pointed out biohacking is a more appropriate term for genetic engineering rather than eating food and drugs. I don't think eating piracetam daily for indefinite periods of time is healthier than not eating it. If anything you might want to stop taking drugs if you want to actually feel good (when not on drugs).
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Barbiturate Research Division
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Moonshoe
Blue Mantis
Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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Quote:
Ellis Dee said:
It sounds a lot like trying to live a healthy lifestyle combined with supplements. When I read biohacking I was thinking of DNA stuff. What came to mind was designer children with enhanced strength, intelligence, and immunity or something along those lines.
Biohacking goes very deep with super advanced and technical stuff , however the purpose of this thread is to introduce people to basic biohacking that is accessible and comprehensible to the average layperson.
That's why I recommended listening to Dave Asprey's podcast for some insight into all the different things biohacking can involve.
Sometimes biohacking has to do with genetically engineering other organisms but it can also have to do with interventions into the biological systems of our own bodies and that is the application of biohacking which interests me.
Other examples of biohacking involve things like bathing yourself in infrared light, using biofeedback technology to gain conscious control over biological processes. That are usually unconscious, doing home gene sequencing and strong a full generic reading of your own DNA etc, implantin magnets under your skin to give you an extra sense ( the ability to detect magnetism), cybernetic implants into your body (pacemakers, prosthetics, implants, etc) partial and progressive Merging of the human organism with technology, genetically engineering designer babies, creating structural changes in the brain through meditation, tinkering with your bodies ph level (becoming more alkaline), using electrical stimulation to enhance brain function , etc etc.
Biohacking overlaps with trans humanism.
It's just that entry level biohacking centers around diet, exercise, supplementation, gadgets and behaviour and psychological Modifications.
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Everything I post is fiction.
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plambe
Trader
Registered: 08/06/08
Posts: 1,071
Last seen: 7 years, 10 months
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Quote:
(becoming more alkaline)
How does that work? I thought the body (as in outside your stomach) maintains a pH in very narrow limits and any deviation is deadly hence the very highly evolved buffer systems (like the HCO3- buffer system in your blood).
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Barbiturate Research Division
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Moonshoe
Blue Mantis
Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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Re: Biohacking [Re: plambe]
#19741428 - 03/24/14 03:12 PM (9 years, 2 months ago) |
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Well there is an entire podcast about ph biohacking . I am not an expert in it. A basic biohack is adding lemon juice to each glass of water that you drink, although acidic in and of itself it has an alkalis of effect on the body. The same is true of apple cider vinegar. Each day put lemon juice in your water and eat a salad with apple cider vinegar and olive oil for dressing . A more extreme biohack is to put 1 tsp of Baking soda In a glass of water each day and drink it.
Avoid acidifying foods like coffee, alcohol and sugar and eat alkalinity foods like green veggies.
The theory is that disease thrives in an acidic internal environment and because of
Our unhealthy diets and lifestyles most of us have an acidic internal environment and moving the body to a more alkaline state is beneficial for health.
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Everything I post is fiction.
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Alan Rockefeller
Mycologist
Registered: 03/10/07
Posts: 47,919
Last seen: 21 hours, 47 minutes
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Nothing you eat will change the ph level of your blood - Your body buffers that very carefully.
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