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Invisiblebadchad
Mad Scientist

Registered: 03/02/05
Posts: 13,373
Re: Banks Say No to Marijuana Money, Legal or Not (SEATTLE,WA) [Re: D.M.T] * 1
    #19416598 - 01/14/14 09:59 AM (10 years, 1 month ago)

Quote:

D.M.T said:
Heroin, LSD and ecstasy certainly aren't the most dangerous drugs out there. Plus all three have medical value.




Generally, the law interprets "medical value" as large scale, Phase 3 type studies performed under appropriately blinded conditions.  You'll find that most of the published studies don't fit these criteria, and are done in (at most) 20-30 subjects.


--------------------
...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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OfflineD.M.T
Shroomery Contaminant
Female

Registered: 10/31/09
Posts: 10,991
Loc: In your brain
Last seen: 4 years, 2 months
Re: Banks Say No to Marijuana Money, Legal or Not (SEATTLE,WA) [Re: badchad]
    #19416673 - 01/14/14 10:17 AM (10 years, 1 month ago)

True but you'll also find the same looking at FDA-approved medications. particularly anti-psychotic medications there is little to no research done before it's approved. There's more on marijuana in academia than almost all medication on the market.

oh and heroin, LSD and MDMA still have medical value and definitely aren't the most dangerous drugs out there. :grin:


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Invisiblebadchad
Mad Scientist

Registered: 03/02/05
Posts: 13,373
Re: Banks Say No to Marijuana Money, Legal or Not (SEATTLE,WA) [Re: D.M.T]
    #19416736 - 01/14/14 10:34 AM (10 years, 1 month ago)

Quote:

D.M.T said:
True but you'll also find the same looking at FDA-approved medications. particularly anti-psychotic medications there is little to no research done before it's approved.




False.  Each have undergone Phase 3 trials with several hundred patients, plus Phase 2 and 3 that usually enroll hundreds more.

The problem with the academic literature on MJ and other drugs, is that its a mish-mash of studies, all with different subject populations, different  endpoints, methods, etc.  You can't just group them all together.

You're correct that "dangerous" is completely different than medical value (i.e., efficacy).


--------------------
...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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OfflineD.M.T
Shroomery Contaminant
Female

Registered: 10/31/09
Posts: 10,991
Loc: In your brain
Last seen: 4 years, 2 months
Re: Banks Say No to Marijuana Money, Legal or Not (SEATTLE,WA) [Re: badchad] * 1
    #19416804 - 01/14/14 10:48 AM (10 years, 1 month ago)

Well that's post-80s and the reason for three phases is because in the 80s, several companies were caught bribing the FDA and entering completely fraudulent data to get approval. I remember reading about it back then.

The big names are still surrounded by scandal to this day - bribing doctors to recommend for off-label purposes for example. I'd not be the least bit surprised if the data for those meds are still fabricated.


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Invisibleunknown1123
Experimental

Registered: 05/15/08
Posts: 5,813
Re: Banks Say No to Marijuana Money, Legal or Not (SEATTLE,WA) [Re: D.M.T]
    #19416911 - 01/14/14 11:20 AM (10 years, 1 month ago)

Quote:

D.M.T said:
Well that's post-80s and the reason for three phases is because in the 80s, several companies were caught bribing the FDA and entering completely fraudulent data to get approval. I remember reading about it back then.

The big names are still surrounded by scandal to this day - bribing doctors to recommend for off-label purposes for example. I'd not be the least bit surprised if the data for those meds are still fabricated.



I guess you can't get over the fact presented to you


--------------------


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OfflineD.M.T
Shroomery Contaminant
Female

Registered: 10/31/09
Posts: 10,991
Loc: In your brain
Last seen: 4 years, 2 months
Re: Banks Say No to Marijuana Money, Legal or Not (SEATTLE,WA) [Re: unknown1123]
    #19416959 - 01/14/14 11:33 AM (10 years, 1 month ago)

^ Who's that guy?


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OfflineLord_McLovin
mad scientist on shrooms
Male User Gallery


Registered: 04/09/11
Posts: 3,071
Loc: infinite dimensional void
Last seen: 6 years, 2 months
Re: Banks Say No to Marijuana Money, Legal or Not (SEATTLE,WA) [Re: badchad]
    #19422818 - 01/15/14 01:17 PM (10 years, 1 month ago)

Quote:

badchad said:
Quote:

D.M.T said:
Heroin, LSD and ecstasy certainly aren't the most dangerous drugs out there. Plus all three have medical value.




Generally, the law interprets "medical value" as large scale, Phase 3 type studies performed under appropriately blinded conditions.  You'll find that most of the published studies don't fit these criteria, and are done in (at most) 20-30 subjects.




Yes, but only because such studies were not allowed to be done or funded in the first place.


--------------------
Stand up. You're not alone.


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