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OfflinePatlal
You ask too many questions
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Registered: 10/09/10
Posts: 44,812
Loc: Ottawa Flag
Last seen: 18 hours, 22 minutes
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: Prisoner#1]
    #19408213 - 01/12/14 12:45 PM (10 years, 1 month ago)

Quote:

Prisoner#1 said:
Quote:

zappaisgod said:
Quote:

Prisoner#1 said:
Quote:

Jvells said:
did you know that mexico is now considered fatter than us on average. I just thought i'd throw that out there, least we aren't known as the fattest fucks anymore lol  :thatsinteresting:





england and australia also passed us, canada is right behind us and going to take the lead

clearly obesity is an american problem though



If suspect that if you controlled for race Canadian Caucasians would prove to be fatter than US Caucasians





obese canadian: I'm just big boned
average 'murcan: bitch, bones dont jiggle when you walk




HAHhahahahHA

I'm totally gonna say that to a fat chick one day. I don't care about the consequences.

:lolsy:


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Offlinezappaisgod
horrid asshole


Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 7 years, 8 months
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: fapjack]
    #19408223 - 01/12/14 12:48 PM (10 years, 1 month ago)

Quote:

fapjack said:
Quote:

zappaisgod said:
I want freedom of choice.  I don't give a fuck what anybody else wants as long as it doesn't shit on MY freedom of choice.  If you want to have your choices limited join a cult. 

There is no "we" that includes me and the nannystaters




Do you believe in restriction of antibiotics?  Their overuse effects everyone, and as such will make them useless within the next 100 years.




That's why they make new ones but I don't think they should be routinely given to healthy animals.  Which practice has nothing to do with protecting humans from disease as you seem to think.


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Offlinezappaisgod
horrid asshole


Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 7 years, 8 months
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: Patlal]
    #19408229 - 01/12/14 12:49 PM (10 years, 1 month ago)

Quote:

Patlal said:
Quote:

Prisoner#1 said:
Quote:

zappaisgod said:
Quote:

Prisoner#1 said:



england and australia also passed us, canada is right behind us and going to take the lead

clearly obesity is an american problem though



If suspect that if you controlled for race Canadian Caucasians would prove to be fatter than US Caucasians





obese canadian: I'm just big boned
average 'murcan: bitch, bones dont jiggle when you walk




HAHhahahahHA

I'm totally gonna say that to a fat chick one day. I don't care about the consequences.

:lolsy:



Why don't you be a man and say it to a fat guy?


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Offlinekoods
Ribbit
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Registered: 05/26/11
Posts: 106,408
Loc: Maryland/DC Burbs
Last seen: 36 minutes, 49 seconds
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: zappaisgod]
    #19408256 - 01/12/14 12:56 PM (10 years, 1 month ago)

Quote:

zappaisgod said:
Quote:

fapjack said:
Quote:

zappaisgod said:
I want freedom of choice.  I don't give a fuck what anybody else wants as long as it doesn't shit on MY freedom of choice.  If you want to have your choices limited join a cult. 

There is no "we" that includes me and the nannystaters




Do you believe in restriction of antibiotics?  Their overuse effects everyone, and as such will make them useless within the next 100 years.




That's why they make new ones but I don't think they should be routinely given to healthy animals.  Which practice has nothing to do with protecting humans from disease as you seem to think.




Nobody is making new ones. Pharmaceutical companies have essentially stopped R&D on new antibiotics because there is not enough profit in them and government spending cuts means not much is going on in the public sector. Let down by the free market once again.


--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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OfflinePatlal
You ask too many questions
Male User Gallery


Registered: 10/09/10
Posts: 44,812
Loc: Ottawa Flag
Last seen: 18 hours, 22 minutes
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: zappaisgod]
    #19408284 - 01/12/14 01:04 PM (10 years, 1 month ago)

Quote:

zappaisgod said:
Quote:

Patlal said:
Quote:

Prisoner#1 said:
Quote:

zappaisgod said:

If suspect that if you controlled for race Canadian Caucasians would prove to be fatter than US Caucasians





obese canadian: I'm just big boned
average 'murcan: bitch, bones dont jiggle when you walk




HAHhahahahHA

I'm totally gonna say that to a fat chick one day. I don't care about the consequences.

:lolsy:



Why don't you be a man and say it to a fat guy?




Because fat guys don't try to hide the fact that their fat. It's a female thing


--------------------


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Offlinezappaisgod
horrid asshole


Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 7 years, 8 months
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: Patlal]
    #19408347 - 01/12/14 01:23 PM (10 years, 1 month ago)

Quote:

Patlal said:
Quote:

zappaisgod said:
Quote:

Patlal said:
Quote:

Prisoner#1 said:



obese canadian: I'm just big boned
average 'murcan: bitch, bones dont jiggle when you walk




HAHhahahahHA

I'm totally gonna say that to a fat chick one day. I don't care about the consequences.

:lolsy:



Why don't you be a man and say it to a fat guy?




Because fat guys don't try to hide the fact that their fat. It's a female thing




That isn't something you can hide and I've heard that big boned shit from men before.  No, it's because you are afraid you'll get your ass kicked


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Offlinezappaisgod
horrid asshole


Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 7 years, 8 months
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: koods]
    #19408404 - 01/12/14 01:38 PM (10 years, 1 month ago)

Quote:

koods said:
Quote:

zappaisgod said:
Quote:

fapjack said:
Quote:

zappaisgod said:
I want freedom of choice.  I don't give a fuck what anybody else wants as long as it doesn't shit on MY freedom of choice.  If you want to have your choices limited join a cult. 

There is no "we" that includes me and the nannystaters




Do you believe in restriction of antibiotics?  Their overuse effects everyone, and as such will make them useless within the next 100 years.




That's why they make new ones but I don't think they should be routinely given to healthy animals.  Which practice has nothing to do with protecting humans from disease as you seem to think.




Nobody is making new ones. Pharmaceutical companies have essentially stopped R&D on new antibiotics because there is not enough profit in them and government spending cuts means not much is going on in the public sector. Let down by the free market once again.




ORLY?

http://www.centerwatch.com/drug-information/fda-approvals/

You don't want to pay for anything but you insist they commit billions with no guarantee of a return.


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Offlinekoods
Ribbit
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Registered: 05/26/11
Posts: 106,408
Loc: Maryland/DC Burbs
Last seen: 36 minutes, 49 seconds
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: zappaisgod]
    #19408466 - 01/12/14 01:54 PM (10 years, 1 month ago)

One new antibiotic last year? That's worse than I thought.


--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlinezappaisgod
horrid asshole


Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 7 years, 8 months
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: koods]
    #19408467 - 01/12/14 01:54 PM (10 years, 1 month ago)

:facepalm:


--------------------


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InvisiblePrisoner#1
Even Dumber ThanAdvertized!
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Registered: 01/22/03
Posts: 193,665
Loc: Pvt. Pubfag NutSuck
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: koods]
    #19408472 - 01/12/14 01:55 PM (10 years, 1 month ago)

Quote:

koods said:
One new antibiotic last year? That's worse than I thought.





you're expecting hundreds? when there's dozens of products on the market that
are effective what's the point in developing dozens more the next day?


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Offlinekoods
Ribbit
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Registered: 05/26/11
Posts: 106,408
Loc: Maryland/DC Burbs
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Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: Prisoner#1]
    #19408486 - 01/12/14 01:58 PM (10 years, 1 month ago)

Quote:

Prisoner#1 said:
Quote:

koods said:
One new antibiotic last year? That's worse than I thought.





you're expecting hundreds? when there's dozens of products on the market that
are effective what's the point in developing dozens more the next day?



Ten years ago there would have been a dozen new antibiotics per year. And the point is that these effective products are losing their effectiveness.


--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlinek00laid
NEMO
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Registered: 05/03/10
Posts: 19,636
Last seen: 6 months, 29 days
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: koods]
    #19408496 - 01/12/14 02:01 PM (10 years, 1 month ago)

isnt this just the nature of antibiotics?
the bacteria eventually just changes to accept it


--------------------
AMU - AMU Q & A - MyVideo Teks!


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Offlinezappaisgod
horrid asshole


Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 7 years, 8 months
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: koods]
    #19408513 - 01/12/14 02:06 PM (10 years, 1 month ago)

Quote:

koods said:
Quote:

Prisoner#1 said:
Quote:

koods said:
One new antibiotic last year? That's worse than I thought.





you're expecting hundreds? when there's dozens of products on the market that
are effective what's the point in developing dozens more the next day?



Ten years ago there would have been a dozen new antibiotics per year. And the point is that these effective products are losing their effectiveness.



Nope
http://www.centerwatch.com/drug-information/fda-approved-drugs/year/2003

Not 1995 either
http://www.centerwatch.com/drug-information/fda-approved-drugs/year/1995

All that information was available at the link I provided which you didn't bother to study.  Lazy.


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Offlinekoods
Ribbit
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Posts: 106,408
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Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: k00laid]
    #19408547 - 01/12/14 02:13 PM (10 years, 1 month ago)

Quote:

k00laid said:
isnt this just the nature of antibiotics?
the bacteria eventually just changes to accept it




Absolutely. That's why there needs to be continual development of novel products, but that has nearly stopped:

http://articles.chicagotribune.com/2013-03-19/health/ct-met-antibiotics-pipeline-20130319_1_drug-resistant-tuberculosis-resistant-bacteria-ketek
Quote:

"The market for a new antibiotic is very small, the rewards are not there and so the capital is not flowing," said Paul Stoffels, pharmaceuticals head at Johnson & Johnson. "In cancer, people pay $30,000, $50,000 or $80,000 (per patient) for a drug, but for an antibiotic it is likely to be only a few hundred dollars."

In December, Stoffels' company won regulatory approval for a new treatment for drug-resistant tuberculosis — a growing issue in many countries. But Johnson & Johnson is not developing any more antibiotics.

Pfizer, once the leader in antibiotics research and development, closed its dedicated center in Connecticut in 2011, to the dismay of many scientists. The company now focuses its anti-bacterial work on vaccines.

Others to have quit include Roche, Bristol-Myers Squibb and Eli Lilly, leaving only a handful of firms like GlaxoSmithKline, AstraZeneca and Merck & Co. in the game. But with basic research providing few new leads for drug targets, they are finding it tough.

Facing difficult decisions about where to invest, AstraZeneca on Monday said it would put less money into developing anti-infectives. "We have to make choices, and we have to focus our investments where we think we can make a substantial difference," CEO Pascal Soriot said.

The number of new systemic antibiotics approved by the U.S. Food and Drug Administration has plunged from 16 between 1983 and 1987 to just two in the past five years, according to the Infectious Diseases Society of America.




--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlinezappaisgod
horrid asshole


Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 7 years, 8 months
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: koods]
    #19408601 - 01/12/14 02:27 PM (10 years, 1 month ago)

I thought you said here were a dozen in 2004?

If there is no market there is no market.  Do you know what a market is otherwise called?  Demand.  We have adequate antibiotics for almost everything.  And, like I said earlier, you don't want to pay for anything.  You want other people to pay.


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InvisiblePrisoner#1
Even Dumber ThanAdvertized!
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Registered: 01/22/03
Posts: 193,665
Loc: Pvt. Pubfag NutSuck
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: koods]
    #19408641 - 01/12/14 02:40 PM (10 years, 1 month ago)

Quote:

koods said:
Quote:

k00laid said:
isnt this just the nature of antibiotics?
the bacteria eventually just changes to accept it




Absolutely. That's why there needs to be continual development of novel products, but that has nearly stopped:

http://articles.chicagotribune.com/2013-03-19/health/ct-met-antibiotics-pipeline-20130319_1_drug-resistant-tuberculosis-resistant-bacteria-ketek
Quote:

"The market for a new antibiotic is very small, the rewards are not there and so the capital is not flowing," said Paul Stoffels, pharmaceuticals head at Johnson & Johnson. "In cancer, people pay $30,000, $50,000 or $80,000 (per patient) for a drug, but for an antibiotic it is likely to be only a few hundred dollars."









the market for cancer drugs is small in comparison to antibiotics, where
they dont make a profit by the pill they do make it in volume, the small
market for some drugs is what results in huge prices, it pays for the R&D
for that drug

http://www.forbes.com/2010/02/19/expensive-drugs-cost-business-healthcare-rare-diseases.html


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OfflinePatlal
You ask too many questions
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Registered: 10/09/10
Posts: 44,812
Loc: Ottawa Flag
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Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: zappaisgod]
    #19408671 - 01/12/14 02:48 PM (10 years, 1 month ago)

Quote:

zappaisgod said:
Quote:

Patlal said:
Quote:

zappaisgod said:
Quote:

Patlal said:


HAHhahahahHA

I'm totally gonna say that to a fat chick one day. I don't care about the consequences.

:lolsy:



Why don't you be a man and say it to a fat guy?




Because fat guys don't try to hide the fact that their fat. It's a female thing




That isn't something you can hide and I've heard that big boned shit from men before.  No, it's because you are afraid you'll get your ass kicked




Why would I be stupid enough to get in fight exactly?


--------------------


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Offlinekoods
Ribbit
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Registered: 05/26/11
Posts: 106,408
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Last seen: 36 minutes, 49 seconds
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: zappaisgod]
    #19408738 - 01/12/14 03:05 PM (10 years, 1 month ago)

Quote:

zappaisgod said:
I thought you said here were a dozen in 2004?

If there is no market there is no market.  Do you know what a market is otherwise called?  Demand.  We have adequate antibiotics for almost everything.  And, like I said earlier, you don't want to pay for anything.  You want other people to pay.




Get your head out of your ass. We need more antibiotics. A free market approach is not appropriate for healthcare.


--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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InvisiblePrisoner#1
Even Dumber ThanAdvertized!
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Registered: 01/22/03
Posts: 193,665
Loc: Pvt. Pubfag NutSuck
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: koods]
    #19408747 - 01/12/14 03:07 PM (10 years, 1 month ago)

Quote:

koods said:
We need more antibiotics.





why?


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Offlinezappaisgod
horrid asshole


Registered: 02/11/04
Posts: 81,741
Loc: Fractallife's gym
Last seen: 7 years, 8 months
Re: Prediction: by 2030, 44% of America will be overweight... Give me a solution to this problem [Re: Patlal]
    #19408760 - 01/12/14 03:09 PM (10 years, 1 month ago)

Quote:

Patlal said:


Why would I be stupid enough to get in fight exactly?




Why would you be stupid enough to be an asshole to a fat chick for no reason?


--------------------


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