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InvisibleCyclohexylamine
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Re: Where in the world would it be legal to synthesize LSD? [Re: s240779]
    #19384985 - 01/07/14 08:46 PM (10 years, 1 month ago)

Quote:

Da2ra said:
Seems like the ergoline alkaloid, lysergol, for example, causes vasocontriction only -- not mental effects: http://advancedchemicla.wordpress.com/2012/02/28/an-introduction-about-lysergol/





I know about lysergol, however goes back to my earlier post " He is assuming things which do not have any proof when there are much simpler explanations.".

Quote:



There is also experiential evidence to support bad acid:


At burning man he knowingly gave away a really bad batch of LSD; you know the muddy black stuff. It caused several people to go into convulsions.

Krystle Cole speaking about Todd Skinner. Interviewed by James Kent. (8/27/05)


The one time I worked with champagne crystal I felt like I was poisoned. It was black nasty shit and I only ate a tiny speck not a thumbprint.

2/2/04. chinacat72. Re: LSD death




That's not evidence at all...


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Qualitative Research Chemical Effects and Experiences
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Offlines240779
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Re: Where in the world would it be legal to synthesize LSD? [Re: maddad]
    #19384992 - 01/07/14 08:47 PM (10 years, 1 month ago)

Quote:

maddad said:
Just read Uncle Festers book on how to make LSD. And then learn about real chemistry and see what he does wrong. There are a few fatal mistakes in that book, all on purpose. Same with the one written about making meth.




Huh?? Are you saying he's a disinformation agent?


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Onlinekoods
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Re: Where in the world would it be legal to synthesize LSD? [Re: Cyclohexylamine]
    #19385010 - 01/07/14 08:50 PM (10 years, 1 month ago)

Quote:

tymoteusz3 said:
Quote:

Da2ra said:


He knows exactly what he's talking about. There are chemicals that are only active somatically. For example, when I was reading up on scopolamine, I learned that the butylbromide salt of scopolamine does not cross the blood-brain-barrier and is used for its somatic properties. The hydrobromide salt, by contrast, is a potent psychoactive.




No he doesn't.  He is assuming things which do not have any proof when there are much simpler explanations.




Yeah. The active dose of LSD is so minute, there's almost no chance that impurities would have any noticeable effect. Even if the LSD was 50% impure and the impurity was cyanide, you wouldn't feel it.


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlines240779
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Re: Where in the world would it be legal to synthesize LSD? [Re: koods]
    #19385064 - 01/07/14 09:01 PM (10 years, 1 month ago)

Quote:

koods said:
Yeah. The active dose of LSD is so minute, there's almost no chance that impurities would have any noticeable effect. Even if the LSD was 50% impure and the impurity was cyanide, you wouldn't feel it.





Albert Hofmann got effects from lysergic acid amide at a dose as low as 500 mcg.[1] You also have to be open to the possibility that the same way LSD is a very potent product of the synthesis, perhaps other ergoline alkaloids are also altered to elicit such an increase in their potency.


[1] See page 209 (digital page: 227)

Albert Hofmann. The active principles of the seeds of Rivea Corymbosa and Ipomoea violacea. Botanical Museum Leaflets (Harvard University), 20, 6, 194–211 (1963).


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Onlinekoods
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Re: Where in the world would it be legal to synthesize LSD? [Re: s240779]
    #19385147 - 01/07/14 09:17 PM (10 years, 1 month ago)

LSD is effective at such low doses because it has an extremely high affinity to a very limited number of receptors. Almost no other compound has acute affects at such a minute dose. Even potent toxins like ricin would be practically harmless at a standard LSD dose.


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


Edited by koods (01/07/14 09:17 PM)


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Offlines240779
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Re: Where in the world would it be legal to synthesize LSD? [Re: koods]
    #19385209 - 01/07/14 09:29 PM (10 years, 1 month ago)

LSD itself causes somatic effects like vasoconstriction.[1] Adverse effects of bad acid could result simply from other ergoloids increasing those somatic effects which are already present. Only a little bit of this or that chemical would be required to increase the effects to a level which causes discomfort. Just a guess.


[1] See page 775.

Stoll, A. and Hofmann, A. (1965) The ergot alkaloids: R.H.F. Manske (ed.), The Alkaloids, Vol. VIII, Academic Press, New York, Chap. 21


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Offlineshivas.wisdom
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Re: Where in the world would it be legal to synthesize LSD? [Re: maddad]
    #19385217 - 01/07/14 09:31 PM (10 years, 1 month ago)

Quote:

maddad said:
For example you should always mix liquids into powders, instead of the other way around. Simple things like that could get you into trouble if you don't know what you are doing.



Pretty sure it's powders into liquids.


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Offlinemaddad
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Re: Where in the world would it be legal to synthesize LSD? [Re: shivas.wisdom]
    #19385275 - 01/07/14 09:40 PM (10 years, 1 month ago)

Quote:

shivas.wisdom said:
Quote:

maddad said:
For example you should always mix liquids into powders, instead of the other way around. Simple things like that could get you into trouble if you don't know what you are doing.



Pretty sure it's powders into liquids.




Yes, you are correct. Sorry, I am a little under the influence...


--------------------
I live in an aura of hope because I live in a twilight world of my own self-generated, cannabinated fantasy, and I forget that not everyone is so fortunate. - Terence McKenna


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Offlineshivas.wisdom
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Re: Where in the world would it be legal to synthesize LSD? [Re: maddad]
    #19385301 - 01/07/14 09:45 PM (10 years, 1 month ago)

lol, sound evidence for sobriety in the lab


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Re: Where in the world would it be legal to synthesize LSD? [Re: shivas.wisdom]
    #19385336 - 01/07/14 09:52 PM (10 years, 1 month ago)

Quote:

Da2ra said:
Quote:

maddad said:
Just read Uncle Festers book on how to make LSD. And then learn about real chemistry and see what he does wrong. There are a few fatal mistakes in that book, all on purpose. Same with the one written about making meth.




Huh?? Are you saying he's a disinformation agent?




I am not saying he is anything. All I am saying is that I wouldn't follow the instructions in any of his books. Why would the government allow such books as The Practical Manufacture of LSD or Meth to be something that can be easily purchased for under $20 on the internet? The book itself states that you should have at least a couple of years of college chemistry to atempt such synthesis. And if you did have that, and really learned something from it, some red flags would stand out about some of the procedures.

You can't trust everything you read, not even what I have just said...


--------------------
I live in an aura of hope because I live in a twilight world of my own self-generated, cannabinated fantasy, and I forget that not everyone is so fortunate. - Terence McKenna


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Invisibleohcrapitsnico
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Re: Where in the world would it be legal to synthesize LSD? [Re: koods]
    #19385341 - 01/07/14 09:53 PM (10 years, 1 month ago)

Quote:

koods said:
LSD is effective at such low doses because it has an extremely high affinity to a very limited number of receptors. Almost no other compound has acute affects at such a minute dose. Even potent toxins like ricin would be practically harmless at a standard LSD dose.




This is incorrect. Depending on RoA, the LD50 of ricin is equivalent to the threshold dose of LSD, roughly 25 micrograms.


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Offlinemaddad
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Re: Where in the world would it be legal to synthesize LSD? [Re: shivas.wisdom]
    #19385350 - 01/07/14 09:54 PM (10 years, 1 month ago)

Quote:

shivas.wisdom said:
lol, sound evidence for sobriety in the lab




Well said.

Except for weed of course...


--------------------
I live in an aura of hope because I live in a twilight world of my own self-generated, cannabinated fantasy, and I forget that not everyone is so fortunate. - Terence McKenna


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Re: Where in the world would it be legal to synthesize LSD? [Re: maddad]
    #19385353 - 01/07/14 09:54 PM (10 years, 1 month ago)

@maddad, someone said the same thing in the Chemistry forum.


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Offlinemaddad
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Re: Where in the world would it be legal to synthesize LSD? [Re: s240779]
    #19385391 - 01/07/14 10:01 PM (10 years, 1 month ago)

Said what same thing?


--------------------
I live in an aura of hope because I live in a twilight world of my own self-generated, cannabinated fantasy, and I forget that not everyone is so fortunate. - Terence McKenna


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Re: Where in the world would it be legal to synthesize LSD? [Re: ohcrapitsnico] * 1
    #19385401 - 01/07/14 10:02 PM (10 years, 1 month ago)

Quote:

ohcrapitsnico said:
Quote:

koods said:
LSD is effective at such low doses because it has an extremely high affinity to a very limited number of receptors. Almost no other compound has acute affects at such a minute dose. Even potent toxins like ricin would be practically harmless at a standard LSD dose.




This is incorrect. Depending on RoA, the LD50 of ricin is equivalent to the threshold dose of LSD, roughly 25 micrograms.




http://www.cdc.gov/biosafety/publications/bmbl5/bmbl5_sect_viii_g.pdf
Quote:

The human lethal dose has not been established rigorously, but may be as low as 1-5 mg of ricin by injection 25 or by the aerosol route



Thats 40 to 200x times the threshold dose of 25μg.


--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offliner00tuuu123
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Re: Where in the world would it be legal to synthesize LSD? [Re: Magicman69]
    #19385408 - 01/07/14 10:03 PM (10 years, 1 month ago)

Quote:

Magicman69 said:
What's harder to create, LSD or MDMA? Just curious. Which one takes more knowledge and needs more difficult to obtain materials?



LSD hands down.


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Re: Where in the world would it be legal to synthesize LSD? [Re: r00tuuu123]
    #19385414 - 01/07/14 10:04 PM (10 years, 1 month ago)

Quote:

r00tuuu123 said:
Quote:

Magicman69 said:
What's harder to create, LSD or MDMA? Just curious. Which one takes more knowledge and needs more difficult to obtain materials?



LSD hands down.




+ safrole oil is probably easier to get than the precursors for L


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Re: Where in the world would it be legal to synthesize LSD? [Re: KingKnowledge]
    #19385434 - 01/07/14 10:06 PM (10 years, 1 month ago)

Quote:

KingKnowledge said:
Quote:

r00tuuu123 said:
Quote:

Magicman69 said:
What's harder to create, LSD or MDMA? Just curious. Which one takes more knowledge and needs more difficult to obtain materials?



LSD hands down.




+ safrole oil is probably easier to get than the precursors for L




Unless you lived next to a very unhealthy field of grain, yes. And, even then, I bet extracting whatever the compound is in the fungus that is the precursor is no simple task.


--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”


Edited by koods (01/07/14 10:08 PM)


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Offlines240779
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Re: Where in the world would it be legal to synthesize LSD? [Re: koods]
    #19385460 - 01/07/14 10:11 PM (10 years, 1 month ago)

If you think you need ergot or ergotamine to make LSD, you're in the dark.


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Re: Where in the world would it be legal to synthesize LSD? [Re: s240779]
    #19385490 - 01/07/14 10:15 PM (10 years, 1 month ago)

Quote:

Da2ra said:
If you think you need ergot or ergotamine to make LSD, you're in the dark.




Well, I'm sure there are other routes. And speaking of in the dark... You have do some of the LSD synthesis in the dark.

If LSD were an easy synth to do, this country would be awash in LSD. Considering how difficult it seems to be to find legitimate acid these days, I would say there aren't too many folks making the stuff.


--------------------
NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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