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Offlineurthtown
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Cluster Busting Trip Report
    #19350423 - 12/31/13 09:38 AM (10 years, 1 month ago)

Hey folks, so I'm a sufferer of semi-annual cluster headaches usually lasting 20-40 days per cycle with intense migraines most days during a cycle. I came across the cluster busting website and got interested in cultivating my own alternative to the extremely expensive triptans I am prescribed as acute treatment and the debilitating calcium channel blockers and beta blockers I've been given as prophylactic therapy.

I had a migraine "ghosting" (there but not yet reaching a high degree of pain, light sensitivity, etc.) yesterday after returning from my holidays and was wishing I had some options for cubes as my initial batch of cakes did not produce anything and my second batch had come down with what looked like a bad case of wet spot bacterial contamination. I did not have time to deal with the contammed cakes before leaving on holiday so I put them in a large rubbermaid in the closet and sealed them away.

To my surprise, the contaminated cakes must have decided to fruit to try to save themselves and a large single fruit had punched through 3 layers of foil and the cap was obviously very dehydrated. Poor fellow! Certainly not ideal or expected but huzzah, I have some medicine!





So I harvested and cleaned the single mature fruit and put the contammed cakes in a separate FC away from the rest of my projects to finish flushing. I'll clean it out later and bleach the perlite, etc. On to the dosing!






So I weighed out 4.49 grams of fresh cubes thinking this would be barely a threshold dose - I was aiming for sub-hallucinogenic as per the cluster buster website advice. Well, this guy was fairly potent as I experienced all the hallmarks of a solid trip (albeit at the low end) but I have 12 years experience with cubes recreationally and have taken as much as 8 grams dried in a single dose and I can tell you what I thought was less than .5 g dry on an empty stomach got me all the way to visual pattern hallucination and intense introspection. Did not expect that - usually I need close to 2g dry to get there. Obviously I have since cloned the specimen - hoping I got a clean xfer to agar to grow out as an isolate. These cakes were a B+ MS syringe from a local head shop.

Here are my notes from the trip:

1:10 pm ingested 4.49 g fresh P. cubensis
1:25 pm vaporized medium sized bowl of strong cannabis
    - marijuana high dominant
    - higher degree of self awareness than normal
    - slight "vibration"
    - first contact with psilocin
    - headache still present, little to no change
1:30 pm - *20 minute mark* vein still throbbing at right temple though pain is less noticeable
1:32 pm - noticeable high on tryptamine
1:40 pm - applied peppermint oil to temples and across crown
1:45 pm - headache pain essentially gone
    - slight gastro/intestinal discomfort
    - temples very cold from peppermint
    - feeling "vibration"
    - can still focus on a feeling that is my headache but no longer as sharp
1:50 pm - headache seems to be migrating further back in head towards base of skull
    - no longer sharp and at temples
2:05 - 2:30 pm stretched out body, strong desire to move
    - visual pattern blurring/melting especially things like wood grain etc. typical baseline visual hallucination
    - closed eye visuals
    - feeling of being very strongly in my body
    - little to no headache, though some remnant still exists it is hard to identify
2:35 pm - headache more present but pain easily manageable
    - acute treatment efficacy still unclear, some pain returning
    - strong "high" given such small dose, for cluster headache treatment easily half this dosage would be sufficient for an isolate of this particular strain

-----------------------
no notes between 2:35 pm and 5:45 pm
-----------------------

Essentially just a long easy come down with lots of introspection and physical sensation, intense arousal, etc. Had some fun with my wife that doesn't need describing. Headache came back - took 200mg Ibuprofen and lay down at 4:00 for about 1 hour.

5:45 pm - slight lingering after glow from tryptamine
    - no headache (probably due to ibuprofen)
    - sensation concentrated in guts
    - easily could take >1/2 this dose for headache therapy

Acute treatment? Well it certainly dealt with the headache while tripping but it totally derailed my day (whoops, oh well was lots of fun) and the headache did come back in the end. I will continue with this low dosage as prophylactic therapy every 5 days and see if I can stop this cycle and then see if I can prevent a subsequent attack with regular, small doses.

Anyways, if anybody else is suffering from cluster headaches and wants to chat about experiences with cubes as acute or prophylactic treatment please comment and let me know your experience! I will keep updating as I go.


Edited by urthtown (01/04/14 01:21 PM)


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InvisibleZarotti
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Re: Cluster Busting Trip Report [Re: urthtown]
    #19350503 - 12/31/13 10:10 AM (10 years, 1 month ago)

do clusterheadaches have to do something with serotonin?
Cause I had cluster headaches for 4-5 years (only once a month)

I took shrooms just tiny ammounts 0.1 -0.2g and I dont have any CH anymore.
(dont know if the shrooms cured it)

MDMA totally empties out the serotonin and decreases the total serotonin levels if you abuse it.

Would abusing MDMA be the cure for clusterheadaches?
Does anyone has experience with this method?


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Offlineurthtown
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Re: Cluster Busting Trip Report [Re: Zarotti]
    #19350572 - 12/31/13 10:32 AM (10 years, 1 month ago)

https://clusterbusters.org/

Tons of information here. Short answer, no, MDMA isn't a cure.

If you didn't have them diagnosed and you had "cluster headaches" once a month then I doubt you actually have ever had cluster headaches. I had mine diagnosed by a neurologist who specialized in migraine research and treatment and I had an MRI and several other tests done to diagnose my condition. If you had a headache once a month it was probably a more common migraine type headache or just a severe tension headache.

Cluster headaches are characteristically occurring in clusters, not as isolated incidents.

from wikipedia:

"The cluster headache, nicknamed the "suicide headache",[citation needed] is a neurological disease that involves, as its most prominent feature, an immense degree of pain in the head. Patients typically experience repeated attacks of excruciatingly severe unilateral headache pain.[1][2] Cluster headache belongs to a group of primary headache disorders, classified as "Trigeminal Autonomic Cephalalgias" or (TACs). There is currently no known cause, or cure for a cluster headache.
Cluster headache attacks often occur periodically; spontaneous remissions may interrupt active periods of pain, though about 10-15% of chronic cluster headache sufferers never remit.[3] The condition affects approximately 0.1% of the population and men are more commonly affected than women, by a ratio of 2.1:1.[4]
The pain of a cluster headache has been described as the most extreme pain a human can possibly endure.[5]"


--------------------
Cluster Headache sufferer? Cluster Busting :thumbup:
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"All mushrooms are edible, but some only once."
-- Croatian Proverb



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Offlinehappygolucky
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Re: Cluster Busting Trip Report [Re: urthtown] * 1
    #19350608 - 12/31/13 10:40 AM (10 years, 1 month ago)

Way to go taking your health into your own hands and reducing the funding to the petro-pharmaceutical-military-media-industrial complex. These natural cures are illegal because they are good for us. It's sad that in the supposed freest nation on earth, which by the way has the largest prison population by far of any other country, you can go to prison for healing yourself.


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Offlineurthtown
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Re: Cluster Busting Trip Report [Re: happygolucky]
    #19353986 - 01/01/14 08:47 AM (10 years, 1 month ago)

Quote:

happygolucky said:
Way to go taking your health into your own hands and reducing the funding to the petro-pharmaceutical-military-media-industrial complex. These natural cures are illegal because they are good for us. It's sad that in the supposed freest nation on earth, which by the way has the largest prison population by far of any other country, you can go to prison for healing yourself.




Hey thanks man, it's been a long pharmaceutical ridden journey to find this solution. The piece of information I came across that really helped was the information on triptans (the medication most used for acute treatment of migraines and cluster headaches):

"Triptans are a family of tryptamine-based drugs used as abortive medication in the treatment of migraines and cluster headaches. They were first introduced in the 1990s. While effective at treating individual headaches, they do not provide preventative treatment and are not considered a cure." - Wikipedia

If tryptamines act on the same receptors, and have evidence for efficacy despite what the drug war would have you believe, why not go with something in its natural form that I have literally years of experience with that can be grown for pennies rather than spending $200 for 5 pills???? Never mind the side effects of verapamil and beta blockers....

Just as an update, yesterday was the first day in 22 days that I didn't need to take ibuprofen!!! Coincidence? Not sure, I'll wait and see how today goes!


--------------------
Cluster Headache sufferer? Cluster Busting :thumbup:
Veil Tear GIF
Flower Pot Grow GIF
Mini Mono Tub GIFS

"All mushrooms are edible, but some only once."
-- Croatian Proverb



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Offlinehappygolucky
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Re: Cluster Busting Trip Report [Re: urthtown]
    #19354301 - 01/01/14 11:05 AM (10 years, 1 month ago)

Glad to hear you're finding some relief. Have a good new year.


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Offlinehushmush

Registered: 12/30/13
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Re: Cluster Busting Trip Report [Re: urthtown]
    #19354587 - 01/01/14 12:43 PM (10 years, 1 month ago)

National Geographic has 2 episodes on hallucinogens.  One on LSD. And another on mushrooms.  They both talk about use for treatment of cluster headaches.


Magic Mushroom video: http://www.dailymotion.com/video/xpehpd_hallucinogens_animals 

LSD: [url=


I also wonder if DMT might be of any help?  That way you might not have to commit a whole day if in a pinch.  Best of luck on your journey to find relief!


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InvisibleBubbles85

Registered: 10/15/12
Posts: 2,884
Loc: England Flag
Re: Cluster Busting Trip Report [Re: hushmush]
    #19354657 - 01/01/14 01:06 PM (10 years, 1 month ago)

Great post OP. I hope that you find a solution to your problem.

I've read on many occasions that Psilocybin can help some people with head aches. Just throwing this out there and have no idea whether it is the mushrooms, a coincidence or some thing else, but i often find that they can induce head aches in my self rather than cure them? My brother has also noted this on several occasions.

Would be interesting to see if this is the case for any one else and exactly why that happens?


Edited by Bubbles85 (01/01/14 01:11 PM)


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Offlineurthtown
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Re: Cluster Busting Trip Report [Re: Bubbles85]
    #19355799 - 01/01/14 06:29 PM (10 years, 1 month ago)

Quote:

Bubbles85 said:
Great post OP. I hope that you find a solution to your problem.

I've read on many occasions that Psilocybin can help some people with head aches. Just throwing this out there and have no idea whether it is the mushrooms, a coincidence or some thing else, but i often find that they can induce head aches in my self rather than cure them? My brother has also noted this on several occasions.

Would be interesting to see if this is the case for any one else and exactly why that happens?




Thanks Bubbles. Everything I have read about tryptamines and triptans being used to treat headaches they have been specifically cluster headaches as opposed to migraines and other tension headaches or secondary type headaches due to whiplash, trauma, etc. The definitions are pretty extensive but the only class of headaches I have seen linked to studies or therapies involving tryptamines are cluster headaches. I just happen to suffer from cluster headaches. Not sure about the relationship between a trip and a tension headache, could be a trigger but again cluster headaches are just different.

I get 'regular' tension headaches or headaches from dehydration or hangovers that are dull, dispersed throbs around the back and top of my head fairly regularly but they are easy to manage with water, rest and a good coffee + meal. My cluster headaches are 1-2 times a year, 30+ days of multiple migraine headaches like a white hot knife stabbing through my right temple and out the base of my skull. My vein on my right temple stands out like a firehose under pressure and throbs with my heartbeat.

Today makes 2 days after my initial dose of tryptamine and 2 days no ibuprofen, no migraines. Still a shadow of "ghost" kicking around but this is really encouraging.

Thanks for the kind words and interest.


--------------------
Cluster Headache sufferer? Cluster Busting :thumbup:
Veil Tear GIF
Flower Pot Grow GIF
Mini Mono Tub GIFS

"All mushrooms are edible, but some only once."
-- Croatian Proverb



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Offlinelovelovelove
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Re: Cluster Busting Trip Report [Re: urthtown]
    #19357068 - 01/02/14 02:10 AM (10 years, 1 month ago)

wow Cluster headaches sound HORRIBLE

so glad you have a fix for them, and you can have fun with your fix too!


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InvisibleBubbles85

Registered: 10/15/12
Posts: 2,884
Loc: England Flag
Re: Cluster Busting Trip Report [Re: urthtown]
    #19357355 - 01/02/14 05:18 AM (10 years, 1 month ago)

Quote:

urthtown said:
Quote:

Bubbles85 said:
Great post OP. I hope that you find a solution to your problem.

I've read on many occasions that Psilocybin can help some people with head aches. Just throwing this out there and have no idea whether it is the mushrooms, a coincidence or some thing else, but i often find that they can induce head aches in my self rather than cure them? My brother has also noted this on several occasions.

Would be interesting to see if this is the case for any one else and exactly why that happens?




Thanks Bubbles. Everything I have read about tryptamines and triptans being used to treat headaches they have been specifically cluster headaches as opposed to migraines and other tension headaches or secondary type headaches due to whiplash, trauma, etc. The definitions are pretty extensive but the only class of headaches I have seen linked to studies or therapies involving tryptamines are cluster headaches. I just happen to suffer from cluster headaches. Not sure about the relationship between a trip and a tension headache, could be a trigger but again cluster headaches are just different.

I get 'regular' tension headaches or headaches from dehydration or hangovers that are dull, dispersed throbs around the back and top of my head fairly regularly but they are easy to manage with water, rest and a good coffee + meal. My cluster headaches are 1-2 times a year, 30+ days of multiple migraine headaches like a white hot knife stabbing through my right temple and out the base of my skull. My vein on my right temple stands out like a firehose under pressure and throbs with my heartbeat.

Today makes 2 days after my initial dose of tryptamine and 2 days no ibuprofen, no migraines. Still a shadow of "ghost" kicking around but this is really encouraging.

Thanks for the kind words and interest.




Thats great to hear, i hope it works it out for you. The head aches i get are just a normal head ache. Nothing on the same level as the cluster head aches you experience.

I also drink a few beers before most trips, so that may play a part in why i get them when i take mushrooms? who knows. But there gone with a few Ibuprofen.

Psilocybin has been a great aid to myself therapeutically to. I've suffered with depression for longer than i care to remember and Psilocybin is the only thing that has really helped with that. Not just helped (or masked the problem like most pharma drugs) but actually cured it. My mind feels stronger than its been for a long time. It really is a wonderful thing :grin:


Edited by Bubbles85 (01/02/14 05:21 AM)


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Offlineurthtown
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Re: Cluster Busting Trip Report [Re: Bubbles85]
    #19357404 - 01/02/14 06:12 AM (10 years, 1 month ago)

As a teenager I used shrooms recreationally to have a lot of fun and get myself into some fairly innocent trouble. Growing up in the woods, we mostly just suited up at winter solstice for the -30Ëšc weather and chowed down running around laughing in the snow.

These days I see a whole range of uses for the experiences I have had - depression and migraine therapy are just two possibilities.

There's a great article in last month's Scientific Mind by Scientific American had an article on using psilocin to treat existential terror:

Article.

Glad to hear they helped you! Day three no headaches - I'll keep updating as I approach my next dose on Saturday.

EDIT: for spelling :frown:


--------------------
Cluster Headache sufferer? Cluster Busting :thumbup:
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"All mushrooms are edible, but some only once."
-- Croatian Proverb



Edited by urthtown (01/02/14 06:12 AM)


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InvisibleBubbles85

Registered: 10/15/12
Posts: 2,884
Loc: England Flag
Re: Cluster Busting Trip Report [Re: urthtown]
    #19357538 - 01/02/14 08:08 AM (10 years, 1 month ago)

I wish psychedelics had been in my life as a teenager. Chances are i never would have had depression?

In my late teens and early twenty's we messed around with lots of party drugs. Stimulants mainly, Coke & MDMA etc. This almost certainly has had alot to do with my condition.

I don't recommended these substances to any one, they slowly destroy you inside.

My first encounter with Psilocybin was only 12 months ago aged 27.

After suffering with depression since my early 20's and being prescribed countless pharmaceutical poisons by my doctor, that did nothing but make things worse. I started to do my own research into natural alternatives and came across Psilocybin.

I've read many articles like the one you posted above and i truly belive in the effects of this substance for many therapeutical purposes.


Edited by Bubbles85 (01/02/14 08:09 AM)


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Offlineurthtown
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Re: Cluster Busting Trip Report [Re: Bubbles85]
    #19362179 - 01/03/14 06:00 AM (10 years, 1 month ago)

Quote:

lovelovelove said:
wow Cluster headaches sound HORRIBLE

so glad you have a fix for them, and you can have fun with your fix too!




Haha yeah no fun, but less terrifying now that I have a better idea what is going on and how to get effective health care myself and via health care professionals.  And like you said, the only side affect is a good trip!

Quote:

Bubbles85 said:
I wish psychedelics had been in my life as a teenager. Chances are i never would have had depression?

I've read many articles like the one you posted above and i truly belive in the effects of this substance for many therapeutical purposes.




Yeah, I'm sure all the hallucinating changed my outlook and my development into an adult. It certainly gave me a kind of scientific spiritualism while I was grappling with my own opinions on the world. I'm very much an anti-theist today, as opposed to one of those "believers", atheists or agnostics but very open to the unknown.

I don't think it was accidental that these DMT based tryptamines have the effects they do on the human brain and where evolution acts, there has to be a clear advantage for the relationship to persist. Especially given that we aren't really certain what cubensis use Psilocin for, so really it's only known use is altering human consciousness. That's a lot of energy for an organism to invest in something... must be a reason somewhere out there.

I'm going to be taking another therapeutic dose today - probably around .3 g dried. I'll post results of this micro dose tonight or tomorrow as part of my ongoing treatment. The migraine "shadow" is still hovering behind my right eye but no acute attacks since Monday after three weeks of daily migraines. I even had a beer last night (alcohol is a major trigger) and shifted my sleep schedule (another trigger) without causing a migraine!!! 

:mushroom2: :justcantwait: :rockon:  :rockon:  :rockon:  :rockon:  :dancer:  :bow2:  :bow2:  :bow2:  :bow2: :justcantwait: :mushroom2:


--------------------
Cluster Headache sufferer? Cluster Busting :thumbup:
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"All mushrooms are edible, but some only once."
-- Croatian Proverb



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Offlinehushmush

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Re: Cluster Busting Trip Report [Re: urthtown]
    #19362378 - 01/03/14 08:11 AM (10 years, 1 month ago)

Keep dosing man!  Wish mushrooms could fix sports injuries


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Offlinelovelovelove
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Re: Cluster Busting Trip Report [Re: urthtown]
    #19362453 - 01/03/14 08:43 AM (10 years, 1 month ago)

Quote:

urthtown said:

Yeah, I'm sure all the hallucinating changed my outlook and my development into an adult. It certainly gave me a kind of scientific spiritualism while I was grappling with my own opinions on the world. I'm very much an anti-theist today, as opposed to one of those "believers", atheists or agnostics but very open to the unknown.

I don't think it was accidental that these DMT based tryptamines have the effects they do on the human brain and where evolution acts, there has to be a clear advantage for the relationship to persist. Especially given that we aren't really certain what cubensis use Psilocin for, so really it's only known use is altering human consciousness. That's a lot of energy for an organism to invest in something... must be a reason somewhere out there.

I'm going to be taking another therapeutic dose today - probably around .3 g dried. I'll post results of this micro dose tonight or tomorrow as part of my ongoing treatment. The migraine "shadow" is still hovering behind my right eye but no acute attacks since Monday after three weeks of daily migraines. I even had a beer last night (alcohol is a major trigger) and shifted my sleep schedule (another trigger) without causing a migraine!!! 





Fantastic! I am so glad you can get relief and even prevent your headaches from returning!

now only if the governments of the world could see the real medical benefits of mushrooms , at least trial them with a view to make them available to those who need them most, of course in in a controlled and regulated environment.

or just stop being d*cks and just make them legal and educate people so people can self medicate!

peace :smile:


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Offlineurthtown
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Re: Cluster Busting Trip Report [Re: lovelovelove]
    #19367407 - 01/04/14 09:50 AM (10 years, 1 month ago)

Hey friends - thanks again for the encouragement and kind words.

I took my second micro-dose last night and had a feeling that a migraine was lurking, shadowing me but not materializing. This is 4 days after my initial dose of 4.49 g fresh P. cubensis.

I took a micro dose of cubes from the same Golden Teacher MS syringe grown on BRF cakes. I had taken a clone of this in vitro pin so I was also curious about the potency as I intend to grow it out as an isolate. These guys were cracker dry so I had a better reference point for dosage as my experience in the past 12 years has been almost exclusively with dry cubes.



I took the dose via lemon tek at 7 pm and was working on finishing some prep on a batch of WBS and getting into the PC. By 7:55 I had a clear sensation in my guts and torso that was coming from the tryptamine in my system. I had a slight nervous energy.

I vaporized a small bowl of marijuana and the initial tender stomach and body vibration (very mild sensations) immediately became a light body high and I became more talkative and relaxed.

This relaxation lasted until shortly after 10:00 pm when I sat down to eat and watch a movie. All in all it was a great micro dose, but I might still try taking less next time - especially of either isolate I am growing out currently. I've never taken such small doses of shrooms before and it's interesting to experience the effects of even the tiniest pinch of them. I'll always have the higher doses for recreational trips but I'd like to get these down to a point where they are effective against the headaches but not going to derail my day if I still need to function. Threshold is the goal.

At one point near the end of the "trip" I felt some headache pain coming on and a throbbing of the vein in my temple but it was as if the pressure and discomfort of the headache were present but the pain just wouldn't materialize. Usually the throbbing and pressure build up mean I'm in for blinding pain lancing through my head. I considered taking an ibuprofen to control the onset but decided I'd rather see if it did turn into an acute attack. I went to bed and slept through the night, no migraine and awoke without an attack occurring. So far so good! Going to keep this going but I'm 4.5 days without a skull splitter knocking me on my ass, so... anecdotally anyway, this is the most effective treatment I've ever been on in 6 years of cluster headache cycles!


--------------------
Cluster Headache sufferer? Cluster Busting :thumbup:
Veil Tear GIF
Flower Pot Grow GIF
Mini Mono Tub GIFS

"All mushrooms are edible, but some only once."
-- Croatian Proverb



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Offlinehushmush

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Re: Cluster Busting Trip Report [Re: urthtown]
    #19367559 - 01/04/14 10:35 AM (10 years, 1 month ago)

That's great news!  Maybe you can try DMT one day and let us know if that's works as well.  You could have a blast off at lunch and be normal 30mins later to go back to work.


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Offlinetruffles
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Re: Cluster Busting Trip Report [Re: urthtown]
    #19367567 - 01/04/14 10:38 AM (10 years, 1 month ago)

I'm just going to hop on here to say that I'm really interested in this thread and I wish you luck with the self-medication! I am a firm believer that going back to naturals is, while not necessarily always, usually the best route to go. There is a reason it evolved in the first place! We try isolating compounds and whatnot, but we always overlook some sort of side reaction and hidden relationship between minor compounds whose absence makes our medicine just a shadow of what can be done. On that same note, pharmacology can also help make medicine better if you figure out those little interactions... I'm going  to stop now haha. My little rant is accomplishing nothing!
Good luck!


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Offlineurthtown
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Re: Cluster Busting Trip Report [Re: truffles]
    #19367602 - 01/04/14 10:52 AM (10 years, 1 month ago)

Quote:

hushmush said:
That's great news!  Maybe you can try DMT one day and let us know if that's works as well.  You could have a blast off at lunch and be normal 30mins later to go back to work.




I would love to. I have thought about trying to extract some - there's reed canary grass everywhere in the ditches where I live. I'll see if I can get that together this year. In any case I always prefer to make my own as I have no interest in supporting organized crime with my headache therapies and I prefer to have control over the quality or the products and process. :thumbup:

Quote:

truffles said:
I'm just going to hop on here to say that I'm really interested in this thread and I wish you luck with the self-medication! I am a firm believer that going back to naturals is, while not necessarily always, usually the best route to go. There is a reason it evolved in the first place! We try isolating compounds and whatnot, but we always overlook some sort of side reaction and hidden relationship between minor compounds whose absence makes our medicine just a shadow of what can be done. On that same note, pharmacology can also help make medicine better if you figure out those little interactions... I'm going  to stop now haha. My little rant is accomplishing nothing!
Good luck!




Thanks Truffles! Haha rant away! I agree with you, I think the path always lies somewhere through the middle but in this case, they were giving me an expensive synthesized triptan which is a medication based on a tryptamine. The huge cost of the drugs is all in the big pharma manufacturing process and research - all to provide a "safer" treatment that doesn't make you hallucinate (drugs are bad). Here I am approaching a threshold dose that has little to no side effect but better efficacy than the synthetic. Isn't it time to let evidence drive further scientific study and leave blind belief by the wayside? 

:mushroom2: :feelsgoodman: :mushroom2:


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