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Asante
Mage


Registered: 02/06/02
Posts: 87,002
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I had a broad spectrum DNA test done, some results surprised me 2
#19346165 - 12/30/13 12:48 PM (10 years, 1 month ago) |
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I had 23 and Me do a full spectrum DNA test of me and got lucky because right after I had my test locked in the FDA banned the company from dispensing medical information, and forced it just to restrict information to ancestry information.
Basically what you do is pay $99 (in Europe €130 due to worldwide express cost) and you'll be sent a tube and a paid for courier express return sleeve. You register the tube, call the courier to schedule a pickup and spit in the tube, package it and give it to the courier guy, then you wait about 1-2 months and presto! your results come in.
Theres a lot of genetic misery in my family, and I was curious and considerably anxious which ones I had picked up, that was my prime reason to do it. Turns out I dodged the bullet of the worst ones, but theres 6 medical conditions of considerable concern (3 cancers among them) that I'll have to look out for as I have significantly increased odds of contracting them. I found out many things I knew, like I have reduced odds of becoming an alcoholic, when smoking I smoke a LOT, but also that I have considerably increased odds of becoming a heroin addict. Unfortunately I have no immunity to Malaria and AIDS, a real bummer, but my odds of getting Parkinson's or Alsheimers are dramatically less than the average population's, so thats reassuring. If found out that one of my habits, drinking lots of milk, is actually unexpectedly wrong for me as it increases the likelyhood of coming down with an active case of 3 of my dirty half dozen. I also know now that my obesity is NOT due to genetics because my genetics at most would pack +10 lbs to my BMI. This is reassuring as I'm perhaps metabolically but not genetically destined to be obese, which makes the odds to lose weight and keep it off better.
Ancestry!
Turns out I have 0.1% black East African genes so that means one of my ancestors was a fullblooded African about 10 generations ago, or at least one with mixed African heritage a shorter while ago. There's also a wee bit Indian/Pakistani genes in me but I am unusually white, 99,8+% West European with 2.4% Neanderthal genes, which is a lot less than most Europeans who have 2,7% neanderthal genes on average. I'm too Sapiens to hang with this crowd 
My father's ancestors were chilling 8,000 BC during the Holocene ice age on the dry land that is now the bottom of the north sea, the lost landmass of Doggerland, which is hilarious cause I was born and raised about 200 miles from there, hold your ground indeed My mother's from a quite rare haplotype that hasnt been pinpointed to a location yet but which likely formed at the crossing over of our ancestors from Africa into the Middle East.
All in all I'm very happy I did that test and beat the FDA in getting the full monty. I got a shitton of medical news that was mostly reassuring and which informed me which things to specifically look out for, and the ancestral news was just a delight to uncover. I know my dad's gonna dig the Doggerland story about his ancestry 10,000 years ago.
All in all, a hundred bucks well spent, my old math teacher said "measuring is knowing" and I'm glad I did.
-------------------- Omnicyclion.org higher knowledge starts here
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Mescalean
Burke is love, burke is life.


Registered: 01/18/12
Posts: 6,755
Last seen: 6 years, 11 months
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: Asante]
#19346186 - 12/30/13 12:51 PM (10 years, 1 month ago) |
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I would want to do it just to know what exactly I am. I know about 75 percent of my lineage the rest is a mystery
-------------------- FREE BURKE
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koods
Ribbit



Registered: 05/26/11
Posts: 106,406
Loc: Maryland/DC Burbs
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: Mescalean]
#19346203 - 12/30/13 12:56 PM (10 years, 1 month ago) |
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Do you have the gene that causes you to inhale more deeply when you smoke? I heard Richard Dawkins discussing that one. The implication is a higher chance of getting lung cancer, but it really isn't a cancer gene at all.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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Into The Woods
Quarantine King


Registered: 04/20/13
Posts: 10,864
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: Asante]
#19346215 - 12/30/13 12:58 PM (10 years, 1 month ago) |
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Wow. That's awesome!
I'd love to have a DNA test done, I wonder how I'd go about it in Australia 
How do they determine your odds of likelihood of becoming an alcoholic/heroin addict?
and neanderthal genes LOL
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Jesus Christ
Savior


Registered: 10/11/13
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: Asante]
#19346216 - 12/30/13 12:58 PM (10 years, 1 month ago) |
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this is interesting. how detailed was the report and did it include any other results/conclusions?
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hidenseek1
Its got all the dinks.
Registered: 12/22/12
Posts: 5,423
Loc: poop
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: Into The Woods]
#19346228 - 12/30/13 01:02 PM (10 years, 1 month ago) |
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shit, how come they arnt aloud to release the medical anymore?
-------------------- You can drink at 7 A.M., because the Beastie Boys fought for that right -------------------------------------------------------------------------- pons asinorum -------------------------------------------------------------------------- lsd and the vietnam war changed music forever
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koods
Ribbit



Registered: 05/26/11
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: hidenseek1]
#19346235 - 12/30/13 01:04 PM (10 years, 1 month ago) |
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Quote:
Mescalean said: I would want to do it just to know what exactly I am. I know about 75 percent of my lineage the rest is a mystery
A lot of people discover that what they thought was their lineage isn't always accurate. Lots of family secrets, and whatnot, I suspect..
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Jesus Christ said: this is interesting. how detailed was the report and did it include any other results/conclusions?
Dude! Do it! Let's find out who your REAL dad is!
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hidenseek1 said: shit, how come they arnt aloud to release the medical anymore?
Because information that has diagnostic medical value must meet a higher standard.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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hidenseek1
Its got all the dinks.
Registered: 12/22/12
Posts: 5,423
Loc: poop
Last seen: 6 years, 11 months
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: koods]
#19346238 - 12/30/13 01:05 PM (10 years, 1 month ago) |
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thats gay a simple disclaimer would do
-------------------- You can drink at 7 A.M., because the Beastie Boys fought for that right -------------------------------------------------------------------------- pons asinorum -------------------------------------------------------------------------- lsd and the vietnam war changed music forever
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koods
Ribbit



Registered: 05/26/11
Posts: 106,406
Loc: Maryland/DC Burbs
Last seen: 4 hours, 11 minutes
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: hidenseek1]
#19346244 - 12/30/13 01:07 PM (10 years, 1 month ago) |
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You probably still get a list of the genes, but they no longer tell you what they mean. You could probably still look them up.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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hidenseek1
Its got all the dinks.
Registered: 12/22/12
Posts: 5,423
Loc: poop
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: hidenseek1]
#19346247 - 12/30/13 01:08 PM (10 years, 1 month ago) |
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i checked the site out, all they do is withhold their interpretation of the data, so im assuming some research you could still figure the health thing out from what they provide
edit: damn beat me to it
-------------------- You can drink at 7 A.M., because the Beastie Boys fought for that right -------------------------------------------------------------------------- pons asinorum -------------------------------------------------------------------------- lsd and the vietnam war changed music forever
Edited by hidenseek1 (12/30/13 01:08 PM)
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Into The Woods
Quarantine King


Registered: 04/20/13
Posts: 10,864
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: koods] 1
#19346254 - 12/30/13 01:09 PM (10 years, 1 month ago) |
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Quote:
koods said:
Quote:
Jesus Christ said: this is interesting. how detailed was the report and did it include any other results/conclusions?
Dude! Do it! Let's find out who your REAL dad is!

I fucking love you, koods 
You make me laugh more than anyone else on these boards
Sorry anyone else
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hidenseek1
Its got all the dinks.
Registered: 12/22/12
Posts: 5,423
Loc: poop
Last seen: 6 years, 11 months
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: Into The Woods]
#19346262 - 12/30/13 01:11 PM (10 years, 1 month ago) |
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i wonder if everyone with neadralthal dna is the same dna, like, could you take everyone's neadralthal dna and have enough dna sequence to create a full neandralthal
-------------------- You can drink at 7 A.M., because the Beastie Boys fought for that right -------------------------------------------------------------------------- pons asinorum -------------------------------------------------------------------------- lsd and the vietnam war changed music forever
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badchad
Mad Scientist

Registered: 03/02/05
Posts: 13,373
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: koods]
#19346273 - 12/30/13 01:16 PM (10 years, 1 month ago) |
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Quote:
koods said:
Quote:
hidenseek1 said: shit, how come they arnt aloud to release the medical anymore?
Because information that has diagnostic medical value must meet a higher standard.
Pretty much this^
The data are incredibly difficult to interpret. To provide a brief example, many people have heard of the BRCA1 and BRCA2 genes. These are the "breast cancer" genes, and some of the most widely studied genetic mutations.
However, these genes only account for " about 20 to 25 percent of hereditary breast cancers", and "55 to 65 percent of women who inherit a harmful BRCA1 mutation and around 45 percent of women who inherit a harmful BRCA2 mutation will develop breast cancer by age 70 years".
So basically, if you have the genes, there's about a coin flip chance of getting cancer by 70. This doesn't really take into account lifestyle factors, interactions with other genes etc.
Essentially, the tests are of questionable clinical relevance. They don't mean a whole lot.
-------------------- ...the whole experience is (and is as) a profound piece of knowledge. It is an indellible experience; it is forever known. I have known myself in a way I doubt I would have ever occurred except as it did. Smith, P. Bull. Menninger Clinic (1959) 23:20-27; p. 27. ...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely. Osmond, H. Annals, NY Acad Science (1957) 66:418-434; p.436
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Asante
Mage


Registered: 02/06/02
Posts: 87,002
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: koods]
#19346277 - 12/30/13 01:16 PM (10 years, 1 month ago) |
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Quote:
Because information that has diagnostic medical value must meet a higher standard.
So they say yes, but I think its more to protect the interest of insurance companies and Big Pharma. I mean if theres 1.2% chance they get a marker wrong, and a condition like my main risk, is based on 12 markers, thats pretty darn unlikely to be incorrect, and they tell you a *tendency to come down with a condition relative to the general population* not diagnose with certainty an existing condition. The FDA is full of shit and I hope they are forced to lift the ban on medical info.
Quote:
Do you have the gene that causes you to inhale more deeply when you smoke?
I don't know but I have always consciously took half a breath of air before my puff of smoke to prevent most of the smoke from reaching my lower airways, were the risk of lethal complications is greatest.
Quote:
how detailed was the report and did it include any other results/conclusions?
Quite. I'm still discovering all what is there. They covered somethging like 230 medical conditions, 25 critical medication sensitivities, carrier status on 50 disorders, a whole bunch of traits and a shitton of ancestral information. Its very well documented.
Quote:
how come they arnt aloud to release the medical anymore?
I'm not sure if its still thye case, because the FDA might have forbidden it, but they might still give the raw data of the medical findings without offering interpretation (and intermretation can be gotten elsewhere online) The company is heavily resisting the restrictions and going for loopholes because of their mission statement to bring as complete as possible genetic information to people without these people having to see a doctor or other official to decide whether they should know things about that which is more their own than anything, their genes.
-------------------- Omnicyclion.org higher knowledge starts here
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Mescalean
Burke is love, burke is life.


Registered: 01/18/12
Posts: 6,755
Last seen: 6 years, 11 months
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: koods]
#19346334 - 12/30/13 01:35 PM (10 years, 1 month ago) |
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Quote:
koods said:
Quote:
Mescalean said: I would want to do it just to know what exactly I am. I know about 75 percent of my lineage the rest is a mystery
A lot of people discover that what they thought was their lineage isn't always accurate. Lots of family secrets, and whatnot, I suspect..
Quote:
Jesus Christ said: this is interesting. how detailed was the report and did it include any other results/conclusions?
Dude! Do it! Let's find out who your REAL dad is!
Quote:
hidenseek1 said: shit, how come they arnt aloud to release the medical anymore?
Because information that has diagnostic medical value must meet a higher standard.
There are tons of family secrets. Certain members of my family shunned and not talked about.
One is supposedly a wiccan or pagan idk the difference. She supposedly is into the darker side of that stuff. Would be a cool person to talk to I think
-------------------- FREE BURKE
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natzyshroomer
Star gazer


Registered: 12/01/12
Posts: 405
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: Mescalean]
#19346375 - 12/30/13 01:46 PM (10 years, 1 month ago) |
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This is awesome But that's quite conspiracy starting for the USDA to not allow health related genetics
Thus fortifies my point ssri's are killing us
-------------------- All submitted posts are by Someone Who Isn't Me and in any event are works of pure fiction or outright lies. Any information, statement, or assertion contained therein should be considered pure unadulterated bullshit
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koods
Ribbit



Registered: 05/26/11
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: natzyshroomer]
#19346437 - 12/30/13 01:59 PM (10 years, 1 month ago) |
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USDA regulates steaks, not DNA tests.
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NotSheekle said “if I believed she was 16 I would become unattracted to her”
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KingKnowledge
Around



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Re: I had a broad spectrum DNA test done, some results surprised me [Re: koods]
#19346461 - 12/30/13 02:06 PM (10 years, 1 month ago) |
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If anybody else finds a source that would do this, I'd happily pay $100 for it. Even more.
I'm just waiting until personal genome sequencers are readily available.
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VivaLaMushie
RIP LS :(


Registered: 07/23/12
Posts: 15,711
Loc: Switzerland
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: Asante]
#19346466 - 12/30/13 02:06 PM (10 years, 1 month ago) |
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Cool post, Wiccan. I enjoyed reading it.
Ive never had a DNA test done where they gave me any results, but I did volunteer to give my saliva to this group of doctors who are trying to find a reason why hyperemesis gravidarum happens to some pregnant women, but not others.
Hmmm now I wonder what is in my DNA.
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hidenseek1
Its got all the dinks.
Registered: 12/22/12
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Loc: poop
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Re: I had a broad spectrum DNA test done, some results surprised me [Re: koods]
#19346468 - 12/30/13 02:06 PM (10 years, 1 month ago) |
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thats what they want you to think, but they are trying to isolate the gene to find which cows are more susceptible to mad cow
-------------------- You can drink at 7 A.M., because the Beastie Boys fought for that right -------------------------------------------------------------------------- pons asinorum -------------------------------------------------------------------------- lsd and the vietnam war changed music forever
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