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HagbardCeline
Student-Teacher-Student-Teacher



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Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during
#19313462 - 12/22/13 07:55 PM (10 years, 2 months ago) |
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Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
I'm sure some of you have seen the articles regarding this lately, supposedly turning two year old mice into mice that appeared only 6 months old. I suspected these articles were misleading and I've done some reading that seems to affirm this belief. The thing I'm unsure about is what the mice in the above study were actually exposed to. ie. What compound and how was it administered?
The title above is the name of the article published in the journal Cell. Does anyone have access to it?
-------------------- I keep it real because I think it is important that a highly esteemed individual such as myself keep it real lest they experience the dreaded spontaneous non-existance of no longer keeping it real. - Hagbard Celine
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Tmethyl
Smear in the shale


Registered: 07/16/12
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Re: Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during [Re: HagbardCeline]
#19313644 - 12/22/13 08:55 PM (10 years, 2 months ago) |
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Thoroughly mind blown.
-------------------- ¯\_(ツ)_/¯
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HagbardCeline
Student-Teacher-Student-Teacher



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Re: Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during [Re: Tmethyl]
#19316415 - 12/23/13 02:20 PM (10 years, 2 months ago) |
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Why?
-------------------- I keep it real because I think it is important that a highly esteemed individual such as myself keep it real lest they experience the dreaded spontaneous non-existance of no longer keeping it real. - Hagbard Celine
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HagbardCeline
Student-Teacher-Student-Teacher



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Re: Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during [Re: HagbardCeline]
#19343222 - 12/29/13 07:46 PM (10 years, 1 month ago) |
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None of you guys at school have access to this journal? If you are not comfortable providing the actual paper, can you just tell me the gist of the substance/administration?
-------------------- I keep it real because I think it is important that a highly esteemed individual such as myself keep it real lest they experience the dreaded spontaneous non-existance of no longer keeping it real. - Hagbard Celine
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presentusthefuture
Stranger


Registered: 09/22/13
Posts: 127
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Re: Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during [Re: HagbardCeline]
#19344373 - 12/30/13 12:33 AM (10 years, 1 month ago) |
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Sorry man. I would, but unfortunately I don't study science anymore so no longer have access...
Do you study? Even if you don't study science, you could still just go to your university's science faculty and ask if you could access this article through their network?
Maybe try entering the title into Google and see if someone posted the entire article?
Try this: http://www.kurzweilai.net/a-new-and-reversible-cause-of-aging
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HagbardCeline
Student-Teacher-Student-Teacher



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Re: Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during [Re: presentusthefuture]
#19345664 - 12/30/13 10:01 AM (10 years, 1 month ago) |
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Awesome! In the comments on the bottom of the page you linked, someone else linked to the Cell paper.
So it was NMN by way of IP injection. For a person to take the necessary dose, it would cost around $43,000/day.
-------------------- I keep it real because I think it is important that a highly esteemed individual such as myself keep it real lest they experience the dreaded spontaneous non-existance of no longer keeping it real. - Hagbard Celine
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presentusthefuture
Stranger


Registered: 09/22/13
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Re: Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during [Re: HagbardCeline]
#19366733 - 01/04/14 02:51 AM (10 years, 1 month ago) |
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Quote:
HagbardCeline said: Awesome! In the comments on the bottom of the page you linked, someone else linked to the Cell paper.
So it was NMN by way of IP injection. For a person to take the necessary dose, it would cost around $43,000/day.
Nice!
$43,000... That's a bargain for a chance to drink from a pseudo-fountain-of-youth.
It'll be interesting to see how this develops.
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420Experience
GC#3




Registered: 08/13/10
Posts: 701
Loc: Searching the Rabbit Hole...
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Re: Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during [Re: HagbardCeline]
#19376960 - 01/06/14 11:39 AM (10 years, 1 month ago) |
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Quote:
HagbardCeline said: Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
I'm sure some of you have seen the articles regarding this lately, supposedly turning two year old mice into mice that appeared only 6 months old. I suspected these articles were misleading and I've done some reading that seems to affirm this belief. The thing I'm unsure about is what the mice in the above study were actually exposed to. ie. What compound and how was it administered?
The title above is the name of the article published in the journal Cell. Does anyone have access to it?
Is this the paper you seek?
-------------------- And as far as I'm concerned, it's like I say, drugs are not the problem. Other stuff is the problem. ~Jerry Garcia I am a catepillar surfing on smoke through Shpongleland...
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