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Invisibleluvdemshrooms
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Marijuana Damages Brain for Life, Study * 3
    #19283125 - 12/16/13 10:22 AM (10 years, 1 month ago)

Well... this (if true) would certainly help explain the stupidity of so many.


Marijuana Damages Brain for Life, Study

The habit of smoking pot during teen years causes long-term brain damage, according to a Northwestern University Feinberg School of Medicine study.

Two years after young adults (early twenties) quit smoking marijuana, researchers found changes in the sub-cortical regions of their brains associated with memory and reasoning, indicating the long-term effects of chronic use. They were also found to perform poorly on memory tests.

"The study links the chronic use of marijuana to these concerning brain abnormalities that appear to last for at least a few years after people stop using it," Matthew Smith, an assistant research professor in psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine and lead study author, said in a press release. "With the movement to decriminalize marijuana, we need more research to understand its effect on the brain."

According to Substance Abuse and Mental Health Services Administration, the marijuana usage by teens, aged 12 to 17, was reduced to 9.5 percent last year from almost 12 percent in 2002. These figures are predicted to increase due to the legalization of marijuana, allowing more access to underage smokers.

For the study, Smith's team compared MRI scans of a controlled group (44) with 10 people with cannabis use disorder, 15 with cannabis use disorder and a diagnosis of schizophrenia, and 28 with schizophrenia but no reported use of marijuana in the past.

The participants, who were aged mid-20s at the time of the testing, had been heavy users as teens.

Through the MRI scans, the researchers found that heavy users displayed abnormalities in all the three brain regions (striatum, thalamus and globus pallidus), irrespective of whether they had schizophrenic disorder or not. The volume of the thalamus was found greatly reduced in heavy users.

Then the participants were asked to undertake four memory tests, like recollecting a sequence of numbers. Heavy users fared badly than healthy controls and non-using schizophrenics.

"The abuse of popular street drugs, such as marijuana, may have dangerous implications for young people who are developing or have developed mental disorders," said co-senior study author John Csernansky, M.D., chair of psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine and Northwestern Memorial Hospital. "This paper is among the first to reveal that the use of marijuana may contribute to the changes in brain structure that have been associated with having schizophrenia."

The finding has been published Monday in the journal Schizophrenia Bulletin.


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You cannot legislate the poor into prosperity by legislating the wealthy out of prosperity. What one person receives without working for another person must work for without receiving. The government cannot give to anybody anything that the government does not first take from somebody else. When half of the people get the idea that they do not have to work because the other half is going to take care of them and when the other half gets the idea that it does no good to work because somebody else is going to get what they work for that my dear friend is the beginning of the end of any nation. You cannot multiply wealth by dividing it. ~ Adrian Rogers


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OfflineDrugsRGood
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Re: Marijuana Damages Brain for Life, Study [Re: luvdemshrooms] * 2
    #19283181 - 12/16/13 10:36 AM (10 years, 1 month ago)

Basically this article says:

Don't do anything even remotely dangerous because you will be damaged permanently.

Let's all just sit at home, shut up, be extremely careful, and don't attempt anything dangerous at all and we will 'live' til we're 100.

Yea, right.


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Life is an adventure; not knowing what's ahead brings a great sense of anticipation; and meeting women is the reward.


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OfflineOliverJames
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Re: Marijuana Damages Brain for Life, Study [Re: luvdemshrooms] * 10
    #19283187 - 12/16/13 10:37 AM (10 years, 1 month ago)

I take everything with a grain of salt when it comes to studies like these. But I'll be honest, this does not really surprise me. I'm no neuroscientist, so I'd never start lecturing someone on the long term effects of marijuana, I simply do not know enough about the brain. Either way, it seems ridiculously naive to believe that smoking marijuana everyday, several times a day, isn't going to cause SOME change. I'm not necessarily saying itll cause damage, but come on, your CONSTANTLY exposing your brain to a psychoactive compound, do people really believe that won't effect their brain.

I'm sure I'll get shit for this post, I'm up for a good debate though. Personally, I love marijuana and I'd love to smoke it everyday, but I don't, partially because it does mess with my memory, I notice it especially when in school, and also because I just think absuing a substance every single day is not wise. But, I believe people should have the right to smoke everyday if they'd like, I've got friends who do, I don't lecure them. I just personally just to keep my smoking to only once or twice a week :shrug:


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OfflineNotTheDevil
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Re: Marijuana Damages Brain for Life, Study [Re: OliverJames] * 5
    #19283220 - 12/16/13 10:45 AM (10 years, 1 month ago)

I'm calling shenanigans.


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OfflineMilkdudTitties
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Re: Marijuana Damages Brain for Life, Study [Re: luvdemshrooms] * 11
    #19283269 - 12/16/13 10:58 AM (10 years, 1 month ago)

Quote:

luvdemshrooms said:
These figures are predicted to increase due to the legalization of marijuana, allowing more access to underage smokers.





:notcoolman:

Go and ask any teenager what is harder for them to get, alcohol or weed.

Almost all of them will say alcohol.

Drug dealers dont card people.


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OfflineLSDreams
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Re: Marijuana Damages Brain for Life, Study [Re: NotTheDevil] * 5
    #19283286 - 12/16/13 11:01 AM (10 years, 1 month ago)

I hate this article. And, I am sensing that they are on the opposite side of legalization. :rolleyes:

Cannabis fucks with your memory... we already knew that. And I swear I saw a news post pretty recently that said marijuana not linked to schizophrenia?

Are they really hoping these studies will prevent cannabis from being legalized? Let us look at 2 drugs that are legal, like alcohol and tobacco. All of their studies must have concluded that they have no negative effects. :doublefacepalm:


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Plants of Interest ~ Lemon Balm, Cannabis, Ayahuasca, Datura, Salvia divinorum, Tabernanthe iboga, Opium poppy, Kratom, Khat, Coca, Ipomoea tricolor, Psilocybin mushrooms, Peyote ~ :peace: 


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OfflineMorel Guy
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Re: Marijuana Damages Brain for Life, Study [Re: LSDreams] * 1
    #19283323 - 12/16/13 11:09 AM (10 years, 1 month ago)

They didn't explain at all how cannabis use changes the brain.  I want to know exactly how cannabis alters neurophysiology.  It seems that all the negative hype about cannabis never shows their work in how they draw conclusions.  I think mj is good, via proof of contradiction.  If mj increased suffering, people wouldn't use it.  Fact is I've only seen someone who sits at home smoking all day, a little more nuerotic.  It helps to toke in the woods.


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"in sterquiliniis invenitur in stercore invenitur"

In filth it will be found in dung it will be found


Edited by Morel Guy (12/16/13 11:11 AM)


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OfflineLSDreams
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Re: Marijuana Damages Brain for Life, Study [Re: Morel Guy] * 1
    #19283360 - 12/16/13 11:19 AM (10 years, 1 month ago)

Quote:

Morel Guy said:
If mj increased suffering, people wouldn't use it.




Then they would say something along the lines of: "well the people cant stop using it because it is so dangerously addictive" :ancientaliens:


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Plants of Interest ~ Lemon Balm, Cannabis, Ayahuasca, Datura, Salvia divinorum, Tabernanthe iboga, Opium poppy, Kratom, Khat, Coca, Ipomoea tricolor, Psilocybin mushrooms, Peyote ~ :peace: 


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Offlinerawrrawr
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Re: Marijuana Damages Brain for Life, Study [Re: Morel Guy] * 2
    #19283414 - 12/16/13 11:33 AM (10 years, 1 month ago)

Quote:

Morel Guy said:
If mj increased suffering, people wouldn't use it.




This, children, is an example of an illogical statement.  There are many substances that increase suffering, people still use them.  Marijuana is not a wonder-drug, it has caused suffering in some people's lives. 

With that said, the issue of legalization should not be centered around an argument of 'safe/unsafe'.  There is an infinite number of ways that people can damage their bodies and their brains without drugs.  As human beings, we should have the freedom to do what we want with our bodies and our minds.  Additionally, we should have the prudence to research the effects of our actions in order to make informed decisions.  Studies like this (if conducted in good faith, without bias) are great, but they are not an argument for (or against) legalizing drug use.


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OfflinePurpleHaze147
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Re: Marijuana Damages Brain for Life, Study [Re: rawrrawr]
    #19283469 - 12/16/13 11:45 AM (10 years, 1 month ago)

Smoking weed daily does clog up the synapses of ur brain since THC is so lipophilic (dissolves in fat easily). This does effect memory and other cognitive functions but it does clear up with time. I wouldn't say it damages ur brain, it inhibits it's maximum potential. It's not nearly as bad as alcohol tho


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:scaryshroom::happyweed::tee:

 


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OfflineLSDreams
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Re: Marijuana Damages Brain for Life, Study [Re: rawrrawr]
    #19283472 - 12/16/13 11:45 AM (10 years, 1 month ago)

I was actually going to say exactly what you said at first, but didnt feel like picking on anybody. :lol:


--------------------
       
Plants of Interest ~ Lemon Balm, Cannabis, Ayahuasca, Datura, Salvia divinorum, Tabernanthe iboga, Opium poppy, Kratom, Khat, Coca, Ipomoea tricolor, Psilocybin mushrooms, Peyote ~ :peace: 


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OfflineCan-i-bus
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Re: Marijuana Damages Brain for Life, Study [Re: LSDreams]
    #19283508 - 12/16/13 11:54 AM (10 years, 1 month ago)

Quote:

The habit of smoking pot during teen years causes long-term brain damage, according to a Northwestern University Feinberg School of Medicine study.




I think abusing any drug during the teen years is not good for a developing brain. Yet they shove adderall and ritalin down kids throats like it's nothing.

I tend to ignore articles like this. It's obvious what their agenda is. I know enough successful and well adjusted potheads to not worry about these "dangerous" long term effects.

I wasn't a "heavy user" till 19 and the brain scans I had at 22 showed absolutely no abnormalities. I've also used mdma which supposedly puts holes in your brain and I had no holes...

Propaganda. Obviously 14 year olds shouldn't be smoking pot but it's going to happen.


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InvisibleEdibleStereos
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Re: Marijuana Damages Brain for Life, Study [Re: rawrrawr]
    #19283524 - 12/16/13 11:58 AM (10 years, 1 month ago)

I believe this could be possible to some degree, however probably not to the extent they are making it out to be. Chronic daily use of any substance is going to have an impact on the mind and brain while it is developing.

But, on the other hand, there isnt much information on the study I could find. I would like to see how they controlled for things like consumption of nicotine, alcohol, and other drugs. Also, how did they concretely confirm that marijuana use caused these issues, and that they were not present before hand. It is possible that these people were predisposed to to addictive behaviours?


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OfflineDylanOM
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Re: Marijuana Damages Brain for Life, Study [Re: LSDreams]
    #19283527 - 12/16/13 11:59 AM (10 years, 1 month ago)

This article doesn't provide any real evidence for its claims, or even make a real point :P. Of course its going to have an effect on your brain, most things you put in your body will, but weed causing brain damage and mental disorders are things that have already been scientifically debunked. It may be habit forming but again, many things are, eating burgers can be habit forming, its not physically addictive and I agree that it effects your memory, but as this is not a long term effect, and its not severe anyway. This study annoys me because it seems like these people are making large assumptions without any actual in-depth research.


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Drugs to do : Alcohol, Weed, Mushrooms, LSD, LSA, MDMA, 25i-NBOMe, 2ci, Ketamine, DoX, 2ce
2cB, 5-MeO-MiPT, 1p-LSD, MXE, DXM, DMT, 4-Aco-DMT, Changa, Mescaline, Ayahuasca


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Offlinesuniced
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Re: Marijuana Damages Brain for Life, Study [Re: DylanOM]
    #19283537 - 12/16/13 12:03 PM (10 years, 1 month ago)

Doesn't suprise me.


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Its not the years in your life that count
                       
            Its the life in your years.


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Onlineshivas.wisdom
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Re: Marijuana Damages Brain for Life, Study [Re: Can-i-bus] * 2
    #19283572 - 12/16/13 12:13 PM (10 years, 1 month ago)

temporary changes to brain chemistry caused by the introduction of a drug ≠ permanent destruction of brain cells (aka, brain damage)

also, the studies used people in the 20s who had started using in their teens--a ten year time frame, max--yet has the audacity to say that the effects carry on for life? Not sure how "brain abnormalities that appear to last for at least a few years after people stop using it" leads one to the sensationalist headline of "marijuana damages brain for life".

though, I think this is more a case of shitty scientific reporting on the side of the university herald, than with the study itself. here is a press release from the researchers that is much more reasonable:

Quote:

Heavy marijuana users have abnormal brain structure and poor memory

Drug abuse appears to foster brain changes that resemble schizophrenia

CHICAGO --- Teens who were heavy marijuana users -- smoking it daily for about three years -- had abnormal changes in their brain structures related to working memory and performed poorly on memory tasks, reports a new Northwestern Medicine® study.

A poor working memory predicts poor academic performance and everyday functioning.

The brain abnormalities and memory problems were observed during the individuals' early twenties, two years after they stopped smoking marijuana, which could indicate the long-term effects of chronic use. Memory-related structures in their brains appeared to shrink and collapse inward, possibly reflecting a decrease in neurons.

The study also shows the marijuana-related brain abnormalities are correlated with a poor working memory performance and look similar to schizophrenia-related brain abnormalities. Over the past decade, Northwestern scientists, along with scientists at other institutions, have shown that changes in brain structure may lead to changes in the way the brain functions.

This is the first study to target key brain regions in the deep subcortical gray matter of chronic marijuana users with structural MRI and to correlate abnormalities in these regions with an impaired working memory. Working memory is the ability to remember and process information in the moment and -- if needed -- transfer it to long-term memory. Previous studies have evaluated the effects of marijuana on the cortex, and few have directly compared chronic marijuana use in otherwise healthy individuals and individuals with schizophrenia.

The younger the individuals were when they started chronically using marijuana, the more abnormally their brain regions were shaped, the study reports. The findings suggest that these regions related to memory may be more susceptible to the effects of the drug if abuse starts at an earlier age.

"The study links the chronic use of marijuana to these concerning brain abnormalities that appear to last for at least a few years after people stop using it," said lead study author Matthew Smith, an assistant research professor in psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine. "With the movement to decriminalize marijuana, we need more research to understand its effect on the brain."

The paper will be published Dec. 16 in the journal Schizophrenia Bulletin.

In the U.S., marijuana is the most commonly used illicit drug and young adults have the highest -- and growing -- prevalence of use. Decriminalization of the drug may lead to greater use.

Because the study results examined one point in time, a longitudinal study is needed to definitively show if marijuana is responsible for the brain changes and memory impairment. It is possible that the abnormal brain structures reveal a pre-existing vulnerability to marijuana abuse. But evidence that the younger a subject started using the drug the greater his brain abnormality indicates marijuana may be the cause, Smith said.

The groups in the study started using marijuana daily between 16 to 17 years of age for about three years. At the time of the study, they had been marijuana free for about two years. A total of 97 subjects participated, including matched groups of healthy controls, subjects with a marijuana use disorder, schizophrenia subjects with no history of substance use disorders, and schizophrenia subjects with a marijuana use disorder. The subjects who used marijuana did not abuse any other drugs.

Few studies have examined marijuana's effect on the deep regions in the brain -- the 'subcortical gray matter' below the noodle-shaped cortex. The study also is unique in that it looked at the shapes of the striatum, globus pallidus and thalamus, structures in the subcortex that are critical for motivation and working memory.

The Marijuana and Schizophrenia Connection

Chronic use of marijuana may contribute to changes in brain structure that are associated with having schizophrenia, the Northwestern research shows. Of the 15 marijuana smokers who had schizophrenia in the study, 90 percent started heavily using the drug before they developed the mental disorder. Marijuana abuse has been linked to developing schizophrenia in prior research.

"The abuse of popular street drugs, such as marijuana, may have dangerous implications for young people who are developing or have developed mental disorders," said co-senior study author John Csernansky, M.D., chair of psychiatry and behavioral sciences at Northwestern University Feinberg School of Medicine and Northwestern Memorial Hospital. "This paper is among the first to reveal that the use of marijuana may contribute to the changes in brain structure that have been associated with having schizophrenia."

Chronic marijuana use could augment the underlying disease process associated with schizophrenia, Smith noted. "If someone has a family history of schizophrenia, they are increasing their risk of developing schizophrenia if they abuse marijuana," he said.

While chronic marijuana smokers and chronic marijuana smokers with schizophrenia both had brain changes related to the drug, subjects with the mental disorder had greater deterioration in the thalamus. That structure is the communication hub of the brain and is critical for learning, memory and communications between brain regions. The brain regions examined in this study also affect motivation, which is already notably impaired in people with schizophrenia.

"A tremendous amount of addiction research has focused on brain regions traditionally connected with reward/aversion function, and thus motivation," noted co-senior study author Hans Breiter, M.D., professor of psychiatry and behavioral sciences and director of the Warren Wright Adolescent Center at Feinberg and Northwestern Memorial. "This study very nicely extends the set of regions of concern to include those involved with working memory and higher level cognitive functions necessary for how well you organize your life and can work in society."

"If you have schizophrenia and you frequently smoke marijuana, you may be at an increased risk for poor working memory, which predicts your everyday functioning," Smith said.

###
The research was supported by grants R01 MH056584 and P50 MH071616 from the National Institute of Mental Health and grants P20 DA026002 and RO1 DA027804 from National Institute of Drug Abuse, all of the National Institutes of Health.




http://www.eurekalert.org/pub_releases/2013-12/nu-hmu121013.php


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Invisibleluvdemshrooms
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Re: Marijuana Damages Brain for Life, Study [Re: DylanOM] * 2
    #19283590 - 12/16/13 12:16 PM (10 years, 1 month ago)

Quote:

DylanOM said:
This article doesn't provide any real evidence for its claims, or even make a real point




Perhaps that's because it's simply an article about the study as opposed to the actual study?

Methinks you be a young cannabis user.


--------------------
You cannot legislate the poor into prosperity by legislating the wealthy out of prosperity. What one person receives without working for another person must work for without receiving. The government cannot give to anybody anything that the government does not first take from somebody else. When half of the people get the idea that they do not have to work because the other half is going to take care of them and when the other half gets the idea that it does no good to work because somebody else is going to get what they work for that my dear friend is the beginning of the end of any nation. You cannot multiply wealth by dividing it. ~ Adrian Rogers


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InvisibleSmushroom
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Re: Marijuana Damages Brain for Life, Study [Re: DylanOM] * 1
    #19283605 - 12/16/13 12:18 PM (10 years, 1 month ago)

This is a news article, they will never publish scientific details, too boring. If you find the journal article the actual results are published in it *should* go into more detail assuming it is a legitimate study.

*If you do find the article online and you need to subscribe to the journal to get it, post a link in the journal article request thread in the chem forum and someone with access will get it for you.

***********

I think this article has merit though. Taking in any drug while your brain is still in development will usually be detrimental. The aritcle seemed to only focus on users that started in adolescence and not ones that waited until they were in the 17-18+ age range. That can make a big difference.

And someone did bring up the adderall and ritalin argument which is only partially true. I do believe they over perscribe ADD/ADHD meds like crazy now but in some cases the benefits truly do outweigh the negative effects. That holds true for most perscription meds, a doctor *should* weigh the pros and cons of taking it before perscribing it. When it comes to recreational drugs a lot of people (especially teenagers) don't look at the negative effects. I don't even think someone under the age of 16-ish can even make an informed decision about self medicating themselves either.

*And that is purely a subjective number. Some people are mature enough at a young age and some aren't, but physiologically I don't believe a young person is ready for drugs*


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OfflinePutrid_herbivore
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Re: Marijuana Damages Brain for Life, Study [Re: suniced]
    #19283631 - 12/16/13 12:23 PM (10 years, 1 month ago)

I have heard of similar results in studies before that have found it can damage memory and brain development, but it doesn't seem to have quite the effect on older peeps. Personally, it has helped me tremendously in my life. I was able to complete my science degree while smoking almost every single night without any noticeable effects of memory loss, certainly not enough to effect my school performance (however, I am NOT recommending that you should smoke weed and study.. Bad idea. I have been smoking gonj for three years now and am comfortable with the effects and I don't smoke when I am trying to learn). It helps me relax which helps me make better decisions. And when you make better decisions you get to live with better consequences, making it easier to enjoy your life more. It makes you think about things in a totally different and unrestricted way.

Some of you guys are right on with your comments about alcohol and tobacco. If we are talking about banning substances because they are dangerous, then lets face the truth and make tobacco and alcohol illegal too. Talk to a police sometime about their experience dealing with drunks.

Personally, I think people should be able to do whatever the frack they want, as long as it doesn't hurt anybody. I think we should be able to take risks against our own health too! Would you rather live a meaningful and exciting life until you're 75 or a boring fearful life until you're 100? I think if religion didn't have such a powerful effect on people's fear, we would all be able to think more rationally and live happier!!!!


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Be true to the world and be true to yourself. Never stop exploring and never be content with what you know.


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OfflineKingKnowledge
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Re: Marijuana Damages Brain for Life, Study [Re: PurpleHaze147]
    #19283637 - 12/16/13 12:25 PM (10 years, 1 month ago)

Quote:

PurpleHaze147 said:
Smoking weed daily does clog up the synapses of ur brain since THC is so lipophilic (dissolves in fat easily). This does effect memory and other cognitive functions but it does clear up with time. I wouldn't say it damages ur brain, it inhibits it's maximum potential. It's not nearly as bad as alcohol tho





Lol what?

Care to explain how THC clogs up synapses to a neuroscience major?


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