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Offlinemellowparty
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Registered: 05/17/09
Posts: 18,467
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Introducing laws on drugs based on receptor activities rather than structure
    #18967174 - 10/12/13 05:02 AM (10 years, 4 months ago)

Most of you know of the federal analogue act thats in force in the US and its sort of efficient (for example compared to the UK misuse act). However, it drives chemists to explore uncharted chemical space with the sole purpose of creating novel structures aimed at the same receptors that are acted upon drugs already covered by the law.

So what if the law-making people came up with a law stating that any chemical having a stimulatory/inhibitory effect over your favourite receptor is automatically illegal to possess, distribute and so on. Of course they'd have to define the assay system but that should be minor technicalities.

In this way your favourite government would ban molecules before they were even conceptualized :gameover:


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Offlinecanid
irregular meat sprocket
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: mellowparty] * 5
    #18967181 - 10/12/13 05:07 AM (10 years, 4 months ago)

out pharma industry would collapse.

fires would break out in the streets.

the streets would fall to old negro wisdom and mob rule.

food would become scarce.

people would 'farm' methane from subterranean pig farms.

barter towns would spring up.

all disputes would be settled in a large domed steel cage.

tina turner would mediate matches and midgets would ride giant developmentally disabled men in leather harness-suspenders.


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Attn PWN hunters: If you should come across a bluing Psilocybe matching P. pellicolusa please smell it.
If you detect a scent reminiscent of Anethole (anise) please preserve a specimen or two for study and please PM me.


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Invisiblebadchad
Mad Scientist

Registered: 03/02/05
Posts: 13,373
Re: Introducing laws on drugs based on receptor activities rather than structure [Re: mellowparty]
    #18967371 - 10/12/13 07:04 AM (10 years, 4 months ago)

This is pretty much the case with a variety of the synthetic cannabinoids.  Once structural criteria are met, only binding and a bit of behavioral data are required for scheduling.


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...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436


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Offlinei like cow poo
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: mellowparty]
    #18967419 - 10/12/13 07:35 AM (10 years, 4 months ago)

Give me shrooms, weed, and mescaline. Thats all I need baby. Of course fuck the government but hey, atleast I got the three sisters.


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OfflineGreySatyr
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Registered: 06/20/13
Posts: 3,376
Loc: North Carolina
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: i like cow poo]
    #18967513 - 10/12/13 08:37 AM (10 years, 4 months ago)

Who cares? We're all rebels anyway. And I need my speed, buddy.


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...also, go to hell, huh?


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OfflinePatlal
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Registered: 10/09/10
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: GreySatyr]
    #18967520 - 10/12/13 08:42 AM (10 years, 4 months ago)

I think it is clear that people are still going to use drugs even if they are illegal.


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Invisiblemillzy
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Registered: 05/12/10
Posts: 12,409
Re: Introducing laws on drugs based on receptor activities rather than structure [Re: Patlal]
    #18967710 - 10/12/13 10:00 AM (10 years, 4 months ago)

they'd have to outlaw chocolate because from my understanding it hits some of the same receptors as psychedelics do. i could be mistaken on that though.


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I'm up to my ears in unwritten words. - J.D. Salinger


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Offlinedstark
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Registered: 02/27/08
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: millzy]
    #18967911 - 10/12/13 11:11 AM (10 years, 4 months ago)

The whole point of making a substance is because it may cause harm to you/people around you, by making all substances that bind to specific receptor illegal is wrong on so many levels! You cant assume anything that binds to at certain receptor is bad, its like the government saying we dont want you to ever get high or anything except alcohol...


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What is a mind, if not something to be messed with? What is consciousness, if not a state to be altered?

~I Feel
:mushroom2:
at Home~


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OfflineNotTheDevil
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Registered: 01/08/13
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: dstark]
    #18968064 - 10/12/13 12:05 PM (10 years, 4 months ago)

Quote:

dstark said:
The whole point of making a substance is because it may cause harm to you/people around you, by making all substances that bind to specific receptor illegal is wrong on so many levels! You cant assume anything that binds to at certain receptor is bad, its like the government saying we dont want you to ever get high or anything except alcohol...



Thats exact what they've been doing for the 60 or so years and they tried to ban the alcohol to.


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Offlinekoods
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: NotTheDevil]
    #18968086 - 10/12/13 12:15 PM (10 years, 4 months ago)

l-methamphetamine is not a controlled substance. always thought that was rather interesting.

Seems that is based more on it receptor activity, than its structure. (Yes, it is 3-D structure that differentiates between the levo and dextro molecules, but they are essentially the same compound in all ways except in the way they interact with receptors)


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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Offlinekoods
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: millzy]
    #18968093 - 10/12/13 12:17 PM (10 years, 4 months ago)

Quote:

millzy said:
they'd have to outlaw chocolate because from my understanding it hits some of the same receptors as psychedelics do. i could be mistaken on that though.




They would have to outlaw all the neurotransmitters, because all they do is tickle receptors.


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NotSheekle said
“if I believed she was 16 I would become unattracted to her”


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InvisibleSalomon
ಠ︵ಠ balance ಠ_ಠ weaver ಠ‿ಠ
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: koods]
    #18968290 - 10/12/13 01:23 PM (10 years, 4 months ago)

so i'll build a device that, once implanted in the brain artificially induces drug experiences through electrical stimulation.


BAN ELECTRICITY 2013


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EVERYTHING EVENTUALLY BECOMES A DESERT



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Offlinepcplease
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Registered: 09/02/11
Posts: 6,089
Last seen: 9 years, 11 months
Re: Introducing laws on drugs based on receptor activities rather than structure [Re: badchad]
    #18968368 - 10/12/13 01:44 PM (10 years, 4 months ago)

Quote:

badchad said:
This is pretty much the case with a variety of the synthetic cannabinoids.  Once structural criteria are met, only binding and a bit of behavioral data are required for scheduling.




This.
It's already begun, OP :tongue2:
:sad:


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Offlinemellowparty
legitimate researcher


Registered: 05/17/09
Posts: 18,467
Last seen: 10 years, 3 months
Re: Introducing laws on drugs based on receptor activities rather than structure [Re: canid]
    #18970535 - 10/12/13 11:46 PM (10 years, 4 months ago)

Quote:

canid said:
out pharma industry would collapse.

fires would break out in the streets.

the streets would fall to old negro wisdom and mob rule.

food would become scarce.

people would 'farm' methane from subterranean pig farms.

barter towns would spring up.

all disputes would be settled in a large domed steel cage.

tina turner would mediate matches and midgets would ride giant developmentally disabled men in leather harness-suspenders.



I'm tempted to put you on ignore cause you haven't posted anything other than complete bullshit in my last 2-3 threads.


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Offlinecanid
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: mellowparty]
    #18970831 - 10/13/13 01:25 AM (10 years, 4 months ago)

I'm hurt.


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Attn PWN hunters: If you should come across a bluing Psilocybe matching P. pellicolusa please smell it.
If you detect a scent reminiscent of Anethole (anise) please preserve a specimen or two for study and please PM me.


Extras: Filter Print Post Top
InvisibleShroomismM
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Re: Introducing laws on drugs based on receptor activities rather than structure [Re: mellowparty]
    #18970996 - 10/13/13 03:13 AM (10 years, 4 months ago)

They would have to outlaw food... that probably wouldn't work out so well.


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