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InvisibleAlien
Galactic Shaman
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Registered: 11/14/99
Posts: 1,868
Loc: Jupiter's Moon
Post deleted by Administrator
    #1886454 - 09/05/03 07:01 PM (20 years, 6 months ago)



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-Alien :cool:

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OfflineLearyfanS
It's the psychedelic movement!
Male User Gallery

Registered: 04/20/01
Posts: 34,184
Loc: High pride!
Last seen: 4 hours, 15 minutes
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: Alien]
    #1886516 - 09/05/03 07:34 PM (20 years, 6 months ago)

HAHAHAHAHAHAHAHAHAHAHAHHAHAHAHAHAHAH





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Mp3 of the month:  Sons Of Adam - Feathered Fish


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OfflineTwirling
Barred Spiral
Male

Registered: 02/03/03
Posts: 2,468
Last seen: 2 years, 1 month
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: Learyfan]
    #1887337 - 09/06/03 12:18 AM (20 years, 6 months ago)

See, this is why IT HELPS TO ACTUALLY THINK when it comes to "scientific reports" and not just believe the headlines.


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The very nature of experience is ineffable; it transcends cognitive thought and intellectualized analysis. To be without experience is to be without an emotional knowledge of what the experience translates into. The desire for the understanding of what life is made of is the motivation that drives us all. Without it, in fear of the experiences what life can hold is among the greatest contradictions; to live in fear of death while not being alive.


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OfflineDemiurge
creator ofworlds

Registered: 04/11/03
Posts: 693
Loc: Florida
Last seen: 13 years, 9 days
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: Learyfan]
    #1887779 - 09/06/03 03:50 AM (20 years, 6 months ago)

Couldn't find the bottle? Mislabeled? I've been in a few labs and all chemicals are meticulously labeled and taked care of. Maybe somebody in on the project just "happened" to switch the bottles. Anybody dare cry CONSPIRACY? I dunno. Just an inkling.


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Just another animal embeded in a technological coral reef extruded psychic objects...

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InvisibleStymee
From here to reality.
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Registered: 03/31/02
Posts: 671
Loc: Seattle, WA Flag
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: Alien]
    #1887970 - 09/06/03 07:18 AM (20 years, 6 months ago)

Here is the original story published by Johns Hopkins. Which is consistantly rated among the best medical institutions in the United States...

Recreational Use of the Drug 'Ecstasy' Causes New Kind of Brain Damage?

Researchers at Johns Hopkins have found that doses of the popular recreational drug "Ecstasy" similar to those that young adults typically take during all-night dance parties cause extensive damage to brain dopamine neurons in nonhuman primates. Brain dopamine cells help control movement, emotional and cognitive responses, and the ability to feel pleasure, according to the study, published in the September 27 issue of Science. The findings may also shed light on the mechanisms by which Ecstasy damages brain cells.

"The most troubling implication of our findings is that young adults using Ecstasy may be increasing their risk for developing parkinsonism, a condition similar to Parkinson's disease, as they get older," said George A. Ricaurte, M.D., associate professor of neurology at The Johns Hopkins University School of Medicine and lead author of the study.

Parkinsonism occurs when brain dopamine neurons are damaged beyond a certain threshold, resulting in a 90 percent or greater loss of brain dopamine, Ricaurte explained. The new findings raise concern that if
Ecstasy damages brain dopamine neurons in humans, as it does in monkeys, parkinsonism could develop years after taking the drug because brain dopamine declines with advancing age, said Ricaurte.

"The lack of obvious immediate harmful effects of Ecstasy is partly responsible for the widely held belief that the drug is safe," said Ricaurte. "But people should be aware that the use of Ecstasy in doses similar to those used in recreational settings can damage brain cells, and this damage can have serious effects."

Ricaurte added that the patterns of Ecstasy use have changed since the 1980s when the drug was taken primarily on college campuses, and individuals typically took one or two doses twice monthly. More recently, many individuals take several sequential doses of the drug over the course of a single night. The new study was part of ongoing efforts to further evaluate the neurotoxic risks posed by Ecstasy to humans, said Ricaurte.

To measure the adverse effects of Ecstasy, also known as MDMA or 3,4-methylene-dioxymethamphetamine, the researchers gave squirrel monkeys three sequential doses of Ecstasy at three-hour intervals. Following this regimen, which is similar to that used by recreational Ecstasy users at all-night parties, they found that in addition to serotonin deficits, which the drug has been known to cause for some time, the monkeys unexpectedly developed severe, long-lasting brain dopamine deficits.

Then, using a variety of techniques to look at a region of the brain called the striatum, they found that 60 percent to 80 percent of the dopaminergic nerve endings were destroyed. To determine if these results were unique to
squirrel monkeys, the researchers performed the experiments again, this time with baboons, and obtained similar findings of neuronal injury.

"We do not yet know if our findings in nonhuman primates will generalize to human beings but, needless to say, this is a major concern," said Ricaurte.

"The message seems clear," added Ricaurte. "The neurotoxic potential of MDMA is high, and use of several sequential recreational doses could have serious, long-term consequences."

Glen R. Hanson, Ph.D., D.D.S., acting director of the National Institute on Drug Abuse, adds, "This study underscores the need for more research about the extent and nature of the damage that Ecstasy may cause. Clearly, the implications of these findings are cause for concern and should serve as a warning to those thinking about using Ecstasy."

Other authors of the study are Jie Yuan, George Hatzidimitriou, Branden J. Cord, and Una D. McCann, all from Johns Hopkins. The study was funded by the U.S. Public Health Service.

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OfflineDreamer987
The VerbalHerman Munster
Female

Registered: 04/15/03
Posts: 5,326
Loc: Texas
Last seen: 16 years, 2 months
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: Alien]
    #1888254 - 09/06/03 10:54 AM (20 years, 6 months ago)

:pill2:  :syringe:
        :shake:


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OfflineHans_Moleman
????

Registered: 04/06/03
Posts: 3,676
Loc: Canadia
Last seen: 16 years, 5 months
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: Dreamer987]
    #1891248 - 09/07/03 02:02 PM (20 years, 6 months ago)

That poor monkey......


just a E-tard!!!


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One of the reasons marijuana is illegal today because growers in the 30s lobbied against hemp farmers -- they saw it as competition, because It is not chemically addictive as is nicotine, alcohol, or caffeine.

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Offlinemonoamine
umask 077(nonefor you)

Registered: 09/06/02
Posts: 3,095
Loc: Jacksonville,FL
Last seen: 18 years, 6 months
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: Stymee]
    #1898204 - 09/09/03 01:02 PM (20 years, 6 months ago)

The guy that did the orginally study,George Ricaurte,is a lying sack of shit. I bet he gives blow jobs to NIDA and DEA agents on a regular basis.
Most scientists really do try to be honest and sometimes politics get the best of them,but this is truly a turd-it wouldn't surprise me if he switched the samples on purpose.

He is one of the people that started this MDMA neurotoxicity garbage,which didn't magically appear until it(MDMA) was up for scheduling in the 80's.

There's a good thread in ODD about this,BTW.


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People think that if you just say the word "hallucinations" it explains everything you want it to explain and eventually whatever it is you can't explain will just go away.It's just a word,it doesn't explain anything...
Douglas Adams

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InvisibleZippoZM
Knomadic
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Registered: 06/17/03
Posts: 13,227
Loc: Pongyang, North Korea
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: monoamine]
    #1901863 - 09/10/03 10:56 AM (20 years, 6 months ago)

Quote:


The guy that did the orginally study,George Ricaurte,is a lying sack of shit. I bet he gives blow jobs to NIDA and DEA agents on a regular basis.
Most scientists really do try to be honest and sometimes politics get the best of them,but this is truly a turd-it wouldn't surprise me if he switched the samples on purpose.

He is one of the people that started this MDMA neurotoxicity garbage,which didn't magically appear until it(MDMA) was up for scheduling in the 80's.





amen! if mdma killed your brain, why didnt alexander shulgin's brain get fried during his weekly use of mdma while writing tihkal. as a matter of fact if alexander shulgin is an example of the damage that mdma does to people, give me some rolls!


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PEACE

:mushroom2:zippoz:mushroom2:



"in times of widespread chaos and confusion, it has been the duty of more advanced human beings - artists, scientists, clowns, and philosophers - to create order. In such times as ours however, when there is too much order, too much m management, too much programming and control, it becomes the duty of superior men and women and women to fling their favorite monkey wrenches into the machinery. To relieve the repression of the human spirit, they must sow doubt and disruption"

"People do it every day, they talk to themselves ... they see themselves as they'd like to be, they don't have the courage you have, to just run with it."

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OfflineSeussA
Error: divide byzero

Folding@home Statistics
Registered: 04/27/01
Posts: 23,480
Loc: Caribbean
Last seen: 1 month, 18 days
Re: Scientists Retract Story on Ecstasy Brain Damage [Re: ZippoZ]
    #1905969 - 09/11/03 02:27 PM (20 years, 6 months ago)

http://story.news.yahoo.com/news?tmpl=st...ence_ecstasy_dc

MANCHESTER, England (Reuters) - Young people would be more likely to ignore warnings about using drugs after scientists retracted a study of the popular "club drug" ecstasy, a leading British scientist said on Thursday.

The research published last year was withdrawn this week after scientists at Johns Hopkins University Medical School in Baltimore realized they had used the wrong drug in the study.

Their research found the drug they had tested might cause brain damage and Parkinson's disease (news - web sites).

"What worries me most about this paper is that I suspect it will have an entirely negative effect on the attitude of young people to the evidence they read about drug risks," Professor Colin Blakemore, of Oxford University, told the British Association for the Advancement of Science (news - web sites) conference.

"They will take nothing seriously now. They will feel themselves deceived and they may well dismiss legitimate evidence for the risk of this and other drugs in the future."

Dr George Ricaurte and his team, who reported the research study on monkeys and baboons in the journal Science last year, said the drug had been mislabeled by the supplier.

But Blakemore, who said he had been confused by the research and had written to the journal, said the error raised concerns about the controls on science and its possible use for political ends.

"What worries me is the problem of this conflict between the desire to produce topical and exciting and headline-catching scientific results and peer-review," Blakemore said, referring to the process of academic peers looking over research ahead of publication in scientific journals.

In a reaction to Blakemore's comments, the journal Science said the study underwent a rigorous review process and there were no political motives in the study.

"We can assure the public that legislative matters had absolutely no bearing on the publication of this research," the magazine said.

"Peer reviewers would have had no way of anticipating this type of error. Science is self-correcting. Unfortunately, an error occurred, and the authors rapidly retracted the manuscript in order to correct the public record," the journal said in a statement.


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Just another spore in the wind.

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