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laughingcat
Chemical Pharmacologist

Registered: 10/02/10
Posts: 41
Loc: UK
Last seen: 10 months, 25 days
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DMT lecture from Breaking Convention 2013 1
#18857588 - 09/18/13 11:36 AM (10 years, 5 months ago) |
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Here is the lecture on DMT I gave at the Breaking Convention Psychedelic Conference 2013 in July - it's just been edited and put up on Vimeo (I suggest you check out the other videos in the series as well!). The content is similar to a lecture I gave last year which might also be up on here somewhere, but the filming was done professionally this time, so much easier to follow! Any questions, just ask. Peace, Andrew. (NB - Excuse the bad McKenna impression at the beginning!)
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Sketch Turner
Eco Warrior

Registered: 05/12/13
Posts: 2,291
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Re: DMT lecture from Breaking Convention 2013 [Re: laughingcat]
#18857774 - 09/18/13 12:22 PM (10 years, 5 months ago) |
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That was an intriguing watch man, I admit some of the neuroscience went over my head but I think you're a pioneer in your field. These forums are lucky to have people like you who are doing great things for the psychedelic community as a whole.
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Moonshoe
Blue Mantis


Registered: 05/28/04
Posts: 27,202
Loc: Iceland
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Re: DMT lecture from Breaking Convention 2013 [Re: laughingcat]
#18857806 - 09/18/13 12:27 PM (10 years, 5 months ago) |
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Wow awesome!
I look forward to watching this. way to go!
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Everything I post is fiction.
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Hashfinger
Nippy Wiffle



Registered: 07/10/12
Posts: 4,775
Loc: Georgia
Last seen: 5 years, 8 months
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Re: DMT lecture from Breaking Convention 2013 [Re: Moonshoe]
#18857868 - 09/18/13 12:46 PM (10 years, 5 months ago) |
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Very cool. Two thumbs up my friend. Have you read the report which confirmed that DMT was present in the pineal of mice? I didn't remember them saying if it was while they were awake or asleep, but it may be like you say, a vestigial neurotransmitter.
-------------------- Species List (Georgia): Psilocybe caerulescens/weilii, Psilocybe atlantis/galindoi, Psilocybe cubensis, Psilocybe ovoideocystidiata, Psilocybe caerulipes, Psilocybe semilanceata, Psilocybe fagicola, Copelandia cyanescens, Panaeolus cinctulus, Panaeolus fimicola, Panaeolus olivaceus, Gymnopilus luteofolius, Gymnopilus aeruginosus, Gymnopilus junonius, Pluteus salicinus (Ohio): Psilocybe ovoideocystidiata, Psilocybe caerulipes, Pluteus cyanopus, Pluteus salicinus sensu lato..., Panaeolus cinctulus, Gymnopilus luteus, Gymnopilus luteofolius, Gymnopilus junonius, Gymnopilus aeruginosus
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laughingcat
Chemical Pharmacologist

Registered: 10/02/10
Posts: 41
Loc: UK
Last seen: 10 months, 25 days
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Re: DMT lecture from Breaking Convention 2013 [Re: Sketch Turner]
#18857874 - 09/18/13 12:48 PM (10 years, 5 months ago) |
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Thanks! I'm glad you enjoyed the talk - I like to think that I have a few new ideas to put out there... I have a paper being published in the next few days which covers everything in a lot more detail, so I'll post it on here - you should find it easier to understand that way, as it's never that easy when just watching a lecture on video...
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laughingcat
Chemical Pharmacologist

Registered: 10/02/10
Posts: 41
Loc: UK
Last seen: 10 months, 25 days
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Re: DMT lecture from Breaking Convention 2013 [Re: Hashfinger]
#18857893 - 09/18/13 12:51 PM (10 years, 5 months ago) |
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Yes I am familiar with the rat pineal study - the problem with trying to draw conclusions from this kind of work is the highly trivial biosynthesis of DMT from tryptophan (2 facile steps), so I'd be surprised if some wasn't found in the rat brain. I'd really like to see psychedelic concentrations in the human brain to be fully convinced, but this is very difficult to achieve experimentally. And, if I'm correct in thinking that DMT is an ancestral neuromodulator, then I don't expect we'll ever see any more than vestigial subpsychedelic concentrations...
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Hashfinger
Nippy Wiffle



Registered: 07/10/12
Posts: 4,775
Loc: Georgia
Last seen: 5 years, 8 months
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Re: DMT lecture from Breaking Convention 2013 [Re: laughingcat]
#18858018 - 09/18/13 01:17 PM (10 years, 5 months ago) |
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Quote:
laughingcat said: Yes I am familiar with the rat pineal study - the problem with trying to draw conclusions from this kind of work is the highly trivial biosynthesis of DMT from tryptophan (2 facile steps), so I'd be surprised if some wasn't found in the rat brain. I'd really like to see psychedelic concentrations in the human brain to be fully convinced, but this is very difficult to achieve experimentally. And, if I'm correct in thinking that DMT is an ancestral neuromodulator, then I don't expect we'll ever see any more than vestigial subpsychedelic concentrations...
Unless... the system is stressed to a degree it feels necessary to really ramp up the production (for whatever purpose that might be). Regarding Native Americans and their connection to "spirit worlds" via fasting, spirit quests (alone in nature), and pain (piercing ceremonies), I think perturbing the system naturally would be a good place to start. I totally think your brain might only release the DMT if it thinks its dying. It would be interesting to see if DMT is released during high anxiety, stress, pain, etc. It could be a natural defense to switch between "realities" if the baseline reality is becoming too painful or too stressful to endure.
-------------------- Species List (Georgia): Psilocybe caerulescens/weilii, Psilocybe atlantis/galindoi, Psilocybe cubensis, Psilocybe ovoideocystidiata, Psilocybe caerulipes, Psilocybe semilanceata, Psilocybe fagicola, Copelandia cyanescens, Panaeolus cinctulus, Panaeolus fimicola, Panaeolus olivaceus, Gymnopilus luteofolius, Gymnopilus aeruginosus, Gymnopilus junonius, Pluteus salicinus (Ohio): Psilocybe ovoideocystidiata, Psilocybe caerulipes, Pluteus cyanopus, Pluteus salicinus sensu lato..., Panaeolus cinctulus, Gymnopilus luteus, Gymnopilus luteofolius, Gymnopilus junonius, Gymnopilus aeruginosus
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laughingcat
Chemical Pharmacologist

Registered: 10/02/10
Posts: 41
Loc: UK
Last seen: 10 months, 25 days
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Re: DMT lecture from Breaking Convention 2013 [Re: Hashfinger]
#18858062 - 09/18/13 01:28 PM (10 years, 5 months ago) |
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This is certainly a possibility, of course assuming that the "DMT is released at the point of death" is correct. If you wanted to study it scientifically, you might struggle to recruit people to be stressed/pained to the point at which their brain thinks they're going to die, but I certainly think that its possible that fasting and piercing etc may induce endogenous production of DMT. Naturally, of course, it's far easier to smoke it these days!
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Hashfinger
Nippy Wiffle



Registered: 07/10/12
Posts: 4,775
Loc: Georgia
Last seen: 5 years, 8 months
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Re: DMT lecture from Breaking Convention 2013 [Re: laughingcat]
#18858165 - 09/18/13 01:47 PM (10 years, 5 months ago) |
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Quote:
laughingcat said: This is certainly a possibility, of course assuming that the "DMT is released at the point of death" is correct. If you wanted to study it scientifically, you might struggle to recruit people to be stressed/pained to the point at which their brain thinks they're going to die, but I certainly think that its possible that fasting and piercing etc may induce endogenous production of DMT. Naturally, of course, it's far easier to smoke it these days!
I would totally volunteer for this, as well as any other DMT or psychedelic-related studies. If you know of any groups doing studies and looking for someone well-versed in both the indigenous and modern applications of entheogens, you know where to find your guy... I really do not fear death, and would put my body and my life towards studying these concepts. If they needed someone to kill in order to see if DMT is released at the point of death, well... I'll be that person if I need to. I think they have plenty of death row candidates for this however. Lol
-------------------- Species List (Georgia): Psilocybe caerulescens/weilii, Psilocybe atlantis/galindoi, Psilocybe cubensis, Psilocybe ovoideocystidiata, Psilocybe caerulipes, Psilocybe semilanceata, Psilocybe fagicola, Copelandia cyanescens, Panaeolus cinctulus, Panaeolus fimicola, Panaeolus olivaceus, Gymnopilus luteofolius, Gymnopilus aeruginosus, Gymnopilus junonius, Pluteus salicinus (Ohio): Psilocybe ovoideocystidiata, Psilocybe caerulipes, Pluteus cyanopus, Pluteus salicinus sensu lato..., Panaeolus cinctulus, Gymnopilus luteus, Gymnopilus luteofolius, Gymnopilus junonius, Gymnopilus aeruginosus
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laughingcat
Chemical Pharmacologist

Registered: 10/02/10
Posts: 41
Loc: UK
Last seen: 10 months, 25 days
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Re: DMT lecture from Breaking Convention 2013 [Re: Hashfinger]
#18858210 - 09/18/13 01:55 PM (10 years, 5 months ago) |
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Well, I'll bear you in mind! What needs to be done before any such studies could commence is to develop a method (almost certainly using advanced pharmMRI techniques) to detect DMT in the living human brain... As a staunch opponent of the death penalty, I'm not sure how I'd feel about those sentenced to death being used for this type of work! (although I realise you were kind of joking!)...
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Hashfinger
Nippy Wiffle



Registered: 07/10/12
Posts: 4,775
Loc: Georgia
Last seen: 5 years, 8 months
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Re: DMT lecture from Breaking Convention 2013 [Re: laughingcat]
#18860263 - 09/18/13 08:50 PM (10 years, 5 months ago) |
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Quote:
laughingcat said: Well, I'll bear you in mind! What needs to be done before any such studies could commence is to develop a method (almost certainly using advanced pharmMRI techniques) to detect DMT in the living human brain... As a staunch opponent of the death penalty, I'm not sure how I'd feel about those sentenced to death being used for this type of work! (although I realise you were kind of joking!)...
I mean, i was joking, but seriously, I think if you offered something like a DMT experience/experiment to death row inmates they might actually want to help out. If I were going to die anyway, I'd want my body or death experience to go to scientific study, but that's just me. Also, knowing the metaphysical implications of DMT, I would almost be begging for it if I were to face death in that way (capital punishment). Shit, we lock criminals away for years in solitary confinement to induce a state of reflection for what they have done, what if we could actually just shoot up criminals with an IV of DMT? They'd probably come out of that 5 minute experience with better results than 50 years in prison. Lol
-------------------- Species List (Georgia): Psilocybe caerulescens/weilii, Psilocybe atlantis/galindoi, Psilocybe cubensis, Psilocybe ovoideocystidiata, Psilocybe caerulipes, Psilocybe semilanceata, Psilocybe fagicola, Copelandia cyanescens, Panaeolus cinctulus, Panaeolus fimicola, Panaeolus olivaceus, Gymnopilus luteofolius, Gymnopilus aeruginosus, Gymnopilus junonius, Pluteus salicinus (Ohio): Psilocybe ovoideocystidiata, Psilocybe caerulipes, Pluteus cyanopus, Pluteus salicinus sensu lato..., Panaeolus cinctulus, Gymnopilus luteus, Gymnopilus luteofolius, Gymnopilus junonius, Gymnopilus aeruginosus
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Sketch Turner
Eco Warrior

Registered: 05/12/13
Posts: 2,291
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Re: DMT lecture from Breaking Convention 2013 [Re: Hashfinger]
#18861501 - 09/19/13 02:45 AM (10 years, 5 months ago) |
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I think that sort of thing would be very beneficial both to the prison and mental health system, try telling that to the authorities though, the function of these institutions seems to be to keep the prisoner/mental health patient from being able to re-integrate into society.
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Hashfinger
Nippy Wiffle



Registered: 07/10/12
Posts: 4,775
Loc: Georgia
Last seen: 5 years, 8 months
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Re: DMT lecture from Breaking Convention 2013 [Re: Sketch Turner]
#18861906 - 09/19/13 08:05 AM (10 years, 5 months ago) |
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Quote:
Cursed Realms said: I think that sort of thing would be very beneficial both to the prison and mental health system, try telling that to the authorities though, the function of these institutions seems to be to keep the prisoner/mental health patient from being able to re-integrate into society.
Exactly. I know people who claim they were never criminals...until they had to go to prison. It forces you to either be a criminal (for defense) or basically get ass-raped. Then you end up tacking on new charges for fighting and violence, and before you know it, you're a new person. And society sure as hell isn't going to let the "new you" back on the streets. Its like, if you spend more than 5 years in prison, they should never even consider letting you back out.
-------------------- Species List (Georgia): Psilocybe caerulescens/weilii, Psilocybe atlantis/galindoi, Psilocybe cubensis, Psilocybe ovoideocystidiata, Psilocybe caerulipes, Psilocybe semilanceata, Psilocybe fagicola, Copelandia cyanescens, Panaeolus cinctulus, Panaeolus fimicola, Panaeolus olivaceus, Gymnopilus luteofolius, Gymnopilus aeruginosus, Gymnopilus junonius, Pluteus salicinus (Ohio): Psilocybe ovoideocystidiata, Psilocybe caerulipes, Pluteus cyanopus, Pluteus salicinus sensu lato..., Panaeolus cinctulus, Gymnopilus luteus, Gymnopilus luteofolius, Gymnopilus junonius, Gymnopilus aeruginosus
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Sketch Turner
Eco Warrior

Registered: 05/12/13
Posts: 2,291
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Re: DMT lecture from Breaking Convention 2013 [Re: Hashfinger]
#18862150 - 09/19/13 09:30 AM (10 years, 5 months ago) |
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I totally agree man, I have a relative who spent time prison, a quite similar story except the way he told it to me goes like this... He was a courier driver (glorified delivery man) or at least this was one the ways that he made a living, after serving a sentence in prison it became difficult to get the work that he used to before he did time. All this eventually led him to being offered certain illegal deliveries, some of which he even had a police escort. The knowledge of what the deliveries contained was never disclosed to him, but he knew that they were shady of course. That's the best I can recall his story he told me when drunk anyway, I suppose its a good thing that he was offered work after prison really, eventually he did manage to get back into doing normal deliveries, at least before he retired. I know that doesn't really add any evidence to the thesis that certain institutions are designed to keep you there, but it's interesting none the less.
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tonpole
Stranger
Registered: 02/12/12
Posts: 102
Last seen: 8 years, 5 months
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Re: DMT lecture from Breaking Convention 2013 [Re: Sketch Turner]
#18863443 - 09/19/13 03:11 PM (10 years, 5 months ago) |
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vimeo doesnt work in most of the world, just the western.
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SomeGuyX
The Ganja Mahn



Registered: 11/04/12
Posts: 1,132
Last seen: 10 months, 27 days
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Re: DMT lecture from Breaking Convention 2013 [Re: tonpole]
#18863742 - 09/19/13 04:32 PM (10 years, 5 months ago) |
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I haven't tried it yet, so my opinion may not be too valid... But... Maybe you just get really fuckin' high when you smoke DMT. And that's it. I mean, that is potentially all it is.
On the hand, ET realities and entities sound pretty damn interesting. This is one of the reasons I am still interested in it. And being able to shift your consciousness to be able to perceive these realities is pretty cool. Like different dimensions. Far out man
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Hashfinger
Nippy Wiffle



Registered: 07/10/12
Posts: 4,775
Loc: Georgia
Last seen: 5 years, 8 months
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Re: DMT lecture from Breaking Convention 2013 [Re: SomeGuyX]
#18863963 - 09/19/13 05:10 PM (10 years, 5 months ago) |
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Quote:
SomeGuyX said: I haven't tried it yet, so my opinion may not be too valid... But... Maybe you just get really fuckin' high when you smoke DMT. And that's it. I mean, that is potentially all it is.
On the hand, ET realities and entities sound pretty damn interesting. This is one of the reasons I am still interested in it. And being able to shift your consciousness to be able to perceive these realities is pretty cool. Like different dimensions. Far out man 
Yeah. Just try it and you'll see. Trust us. Its hookier than words can explain, but I mean that sincerely. Not in a hookie drug sort of way, but as in it leads you down deeper avenues of the state of reality.
-------------------- Species List (Georgia): Psilocybe caerulescens/weilii, Psilocybe atlantis/galindoi, Psilocybe cubensis, Psilocybe ovoideocystidiata, Psilocybe caerulipes, Psilocybe semilanceata, Psilocybe fagicola, Copelandia cyanescens, Panaeolus cinctulus, Panaeolus fimicola, Panaeolus olivaceus, Gymnopilus luteofolius, Gymnopilus aeruginosus, Gymnopilus junonius, Pluteus salicinus (Ohio): Psilocybe ovoideocystidiata, Psilocybe caerulipes, Pluteus cyanopus, Pluteus salicinus sensu lato..., Panaeolus cinctulus, Gymnopilus luteus, Gymnopilus luteofolius, Gymnopilus junonius, Gymnopilus aeruginosus
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SomeGuyX
The Ganja Mahn



Registered: 11/04/12
Posts: 1,132
Last seen: 10 months, 27 days
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Re: DMT lecture from Breaking Convention 2013 [Re: Hashfinger]
#18864001 - 09/19/13 05:19 PM (10 years, 5 months ago) |
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I have a lot I need to work on in this world before I dive into others.
Still need to get better with lucid dreaming, and maybe explore astral projection... And then I can explore further. But all of these things seem to be related, I want to get the most out of it I can, while still keeping my brain in tact lol.
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Hashfinger
Nippy Wiffle



Registered: 07/10/12
Posts: 4,775
Loc: Georgia
Last seen: 5 years, 8 months
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Re: DMT lecture from Breaking Convention 2013 [Re: SomeGuyX]
#18864061 - 09/19/13 05:33 PM (10 years, 5 months ago) |
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Quote:
SomeGuyX said: I have a lot I need to work on in this world before I dive into others.
Still need to get better with lucid dreaming, and maybe explore astral projection... And then I can explore further. But all of these things seem to be related, I want to get the most out of it I can, while still keeping my brain in tact lol.
I think your views might be a little skewed or biased... What do you think the point of using psychedelics should be? As far as I know they are some of the best teachers about this reality, however separate they might be from it. I don't know what you refer to when you say you want to keep your brain in tact... DMT is not going to break your brain. Lol.
-------------------- Species List (Georgia): Psilocybe caerulescens/weilii, Psilocybe atlantis/galindoi, Psilocybe cubensis, Psilocybe ovoideocystidiata, Psilocybe caerulipes, Psilocybe semilanceata, Psilocybe fagicola, Copelandia cyanescens, Panaeolus cinctulus, Panaeolus fimicola, Panaeolus olivaceus, Gymnopilus luteofolius, Gymnopilus aeruginosus, Gymnopilus junonius, Pluteus salicinus (Ohio): Psilocybe ovoideocystidiata, Psilocybe caerulipes, Pluteus cyanopus, Pluteus salicinus sensu lato..., Panaeolus cinctulus, Gymnopilus luteus, Gymnopilus luteofolius, Gymnopilus junonius, Gymnopilus aeruginosus
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Yogi1
Squatchin
Registered: 04/01/13
Posts: 1,015
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Re: DMT lecture from Breaking Convention 2013 [Re: laughingcat]
#18864100 - 09/19/13 05:42 PM (10 years, 5 months ago) |
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I'm watching this video directly after posting this.
What is it you do for a career and what level of a degree did you obtain for said career. Also I'm assuming you dont actually work with DMT but work in another field of research, yes?
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