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Try taking 250mcg. and two weeks later eat two sheets(20,000mcg) and tell me there's no difference.

That's not the same thing. The key is if you think you're getting 250ug you don't notice any difference if it's 2000ug.

If this saturation theory were true , a person recieving a enormous dose would be saturated therefore they would'nt be thinking they were getting a "average hit".

No, if saturation point is at 250-500ug then it doesn't matter if you get 3000, you'll still think it's 250ug.

Why would Leary lie about people being unable to distuingish between 250 and 2000ug? 

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In your statement you said Leary said people getting a enormous dose thought it was average. Can't you see the error in this statement. Lets assume that an Average dose is one that is not fully "saturated". An enormous dose would completely saturate you. So how could you get completely saturated off a dose that doesn't completely saturate your receptors? Thats what your saying when you say an average dose is no different than a enormous dose.

As for Leary lying. Leary isn't a lier. He was a very beautiful ,well intentioned man in a pivatol place in history. He made many mistakes, but so would any person put in his shoes. His research may not have been able to tell the difference between 250mcg and 2000. I don't think he intentionaly lied  ever about anything.

Ask anyone who has ever taken a huge dose of LSD(10,000+mcg.) if it's different than 250mcg. I assure you that they can tell the difference. A huge fuckin difference. As Whiterasta said in the thumbprint thread at huge doses LSD starts acting on other neurotransmitter receptor systems other than the normal ones it effects. I know alot of people from tour who have eaten massive doses of LSD and every one of them felt it was more powerful than 500mcg. By far more powerful.

Since going off info from folks off the net is skeptical I propose a test.
A blind non-placebo test. Take two bottles of water. Have a trusted friend put 250mcg. of liquid LSD in one bottle. Have him put 20,000mcg. in the other. Have him mark them so he knows what they contain, but not tell you. Take them home and drink one then two weeks later drink the other. At both times have your friend be there as a sitter(your going to need it for the 20,000mcg.) I would bet my wife,house, and kids that you will definatly know which one contained the 20,000mcg. In fact you would know it very quickly.
peace
chinacat72  

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Many people have reported very much the opposite of what your debating

No, they've stated that when they know they're taking a big dose they have a big trip. I'm sure that happens. But that's a completly different situation to not knowing what dosage you're taking. As far as I'm aware that's only been examined once - the results were people couldn't distuingish above a dose in the 250-500ug level. 

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Thats crazy. Your giving to much power to placebo. Read the thumbprint thread. I talk about a friend of mine who ate some LSD crystal without any knowlege of it's strength or power. He had eaten 1000mcg. many times before and beleived this would be no different. This trip ended his LSD taking career. He was blasted apart. I have seen this happen with everyone who does a print. We think were ready and it will be no different and then it bitchslaps us into eternity.

Until you try it yourself you'll be sceptical and still base your view on a book by a very wonderful man who wrote alot of things that wern't true(not purposefully).
I base my view off of 20 years experiance of LSD use and watching thousands of people's reactions to LSD on 8 years of touring with the Grateful Dead.
As I said before, I would bet my house, and kids that you would be floored by the difference between 250mcg. and 20'000mcg.(not 2000mcg.).
Until you do this ,it's futile to argue this anymore.

Whiterasta- that book we were talking about is sounding like a better idea every day. When i'm out in Oregon this summer lets toss some idea's around. I know a bunch of family in Eugene thats been printed that would probably be willing to share. Especially if they heard that there were actually people who believed that there's no difference between 250mcg. and a nice chunk of white fluff crystal.