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LINK398
Stranger
Registered: 06/15/09
Posts: 126
Last seen: 10 years, 10 months
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MDMA question
#14607499 - 06/13/11 05:10 PM (12 years, 7 months ago) |
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I possibly plan on rolling later on tonight with some MDMA (molly) the thing is I take Prozac 60mg for OCD. I already know about the risks and such and how the SSRI is suppose to reduce the effects but I've rolled before while on both. Even though people say it reduces the effects greatly it's still possible to roll isnt it? Because I've taken Ecstasy before while on an SSRI (both shitty E and good E) and when I've gotten good E I definitely felt different more then just a speedy feeling and I've taken Molly while on an SSRI and definitely felt different. pretty sure it was rolling also on a side note I've also taken LSD and Mushrooms a bunch while on an SSRI and tripped. So is it possible that I can roll and trip just fine while on this medication just wondering
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LINK398
Stranger
Registered: 06/15/09
Posts: 126
Last seen: 10 years, 10 months
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Re: MDMA question [Re: LINK398]
#14607504 - 06/13/11 05:11 PM (12 years, 7 months ago) |
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While I'm asking does DMT interact with SSRI's because I've done DMT twice while on an SSRI and didn't really feel much but my friend who was also doing it with me wasn't on an SSRI and didn't really feel much either
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healing
Strangest



Registered: 02/22/11
Posts: 6,565
Loc: the universe, the milky w...
Last seen: 6 years, 6 months
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Re: MDMA question [Re: LINK398]
#14607641 - 06/13/11 05:38 PM (12 years, 7 months ago) |
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This is the wrong forum. You need to ask in Physical and Mental Well-Being.
The people there know a lot more about neurology than the people in TPE.
-------------------- Open mind, open heart, open book.
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ifoundwaldo


Registered: 09/28/10
Posts: 8,389
Loc: Denver, CO
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Re: MDMA question [Re: LINK398]
#14607773 - 06/13/11 06:03 PM (12 years, 7 months ago) |
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If you can normally feel the effects of other drugs while on an SSRI, you should be able to feel the MDMA as well.
Put succinctly, the problem is this: The SSRI binds to the same receptor sites as most psychedelics (including MDMA, LSD, mushrooms, DMT) with a higher affinity for those sites. (e.g. 5-HT2A is one such type of receptor site. 5-HT is serotonin; 2A is a serotonin receptor subtype.) Basically, you get competition in your brain between the SSRI and the drugs (both of which are mimicking serotonin and binding to various serotonin receptor sites); if the SSRI wins, your drugs are wasted.
Technically, there is a danger with combining MDMA and an SSRI of serotonin syndrome. In practice, this should not be a problem (though I would take it easy on the MDMA); in fact, I was unable to find a single case of this happening ever- which limits this danger to the realm of speculation (not to reality).
This should be enough information for you. 
I always recommend the following: skip one (and only one) night of your SSRI and potentiate with piracetam if needed. Have fun.
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Edited by ifoundwaldo (06/13/11 06:33 PM)
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abltsandwich
JFK = Jelly Donut




Registered: 06/16/09
Posts: 11,537
Loc: Dildoville
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Re: MDMA question [Re: LINK398]
#14608851 - 06/13/11 09:04 PM (12 years, 7 months ago) |
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I'm pretty sure your description of rolling would be more than "felt different" if you really rolled any of those times. You probably got some effects but I bet you'd roll your face off if you stopped the SSRIs for a few months.
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kushfarts
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Registered: 12/26/10
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Last seen: 11 years, 8 months
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Quote:
abltsandwich said: I'm pretty sure your description of rolling would be more than "felt different" if you really rolled any of those times. You probably got some effects but I bet you'd roll your face off if you stopped the SSRIs for a few months.
^^^ this. friend just got off those meds and was amazed how certain drugs have been kicking his ass as of lately.
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