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willowmp
Medical Psychedelic Mushrooms



Registered: 07/25/08
Posts: 3,346
Last seen: 12 years, 8 months
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My opiate tolerance fucks me over.
It is really kinda gay. I have a natural tolerance to opiates, so it obviously takes more for me to get high off them. The first time I touched OC I had practically no tolerance from usage, and I snorted 60mg of oxy, and puked the next day.
The problem with having the natural tolerance is that I have issues with nausea. I think it is because I haven't built up the tolerance. Like normally the nausea tends to go away as people use it more and more, but it isn't a super big deal because you can escalate your dose as your tolerance rises. It feels like my tolerance was already jacked up to begin with, causing me to feel nauseous every time, because of the high dose.
Well this was off topic, but does that sound logical?
On topic, how does Opana compare in feel to dillies?
-------------------- "Fuck it too much Im outta wittbhjkhbhkjsrglhkrgl g I DEE JEUD." -Because it made sense on xanax and booze...
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Smokeage
arbitrary



Registered: 08/31/10
Posts: 49
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That sucks man, I'm thankful I don't have any natural tolerances .
For me, comparing Opana and Dillys, is kind of like comparing Vicodin and oxy. Dilaudid is more euphoric and less sedating where as the Opana is heavier on the nod, ehh explaining highs isn't my best skill haha.
You just have to try it yourself, everyone reacts differently to everything, but it's a fantastic opiate I can guarantee you that
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Smokeage
arbitrary



Registered: 08/31/10
Posts: 49
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Im about to blow me 10mg more and go on a nice little bike ride in the dark of night I love cruising on opiates
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openmind
curious


Registered: 08/03/07
Posts: 13,902
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Quote:
Smokeage said: ...For me, comparing Opana and Dillys, is kind of like comparing Vicodin and oxy. Dilaudid is more euphoric and less sedating where as the Opana is heavier on the nod....
I would agree with this....And it does make sense as once in your body they are metabolized into a more potent opioid, as follows...
Hydrocodone (Vicoden) ----> Hydromorphone (Dilaudid)
Oxycodone (OC)-----> Oxymorphone (opana)
This is why it is tricky using enzyme inhibitors to potentiate some opiates. If you inhibit the enzyme that metabolizes the opiate into a more potent opioid, in theory you will have prolonged but somewhat diminished effects as the half life is increased but the change into the more potent opiate is more subtle. I would say this stands correct for Oxycodone and Hydrocodone.

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openmind
curious


Registered: 08/03/07
Posts: 13,902
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Quote:
Smokeage said: Im about to blow me 10mg more and go on a nice little bike ride in the dark of night I love cruising on opiates
Nice...Night time bike rides are incredible whilst zooted from opiates especially during warm summer nights, the wind feels amazing. Many times I rode several miles across town from my friends house after blowing opana. I actually get a HUGE stamina & energy boost from opiates.

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Smokeage
arbitrary



Registered: 08/31/10
Posts: 49
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Eminence



Registered: 07/25/10
Posts: 16,627
Loc: Richmond, VA
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I fucking love Opana. Love it. Best opiate ever.
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Abuse
end of the line


Registered: 08/08/08
Posts: 6,039
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never had the privelage of trying dialudid
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s240779


Registered: 12/07/10
Posts: 12,880
Last seen: 3 months, 10 days
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In my opinion oxycodone and hydrocodone are the two best opiates and are on par with each other. Why? Because they have exceptionally high oral bioavailabilities: about 80% from what I understand. I don't want to fuck around with other, ridiculous methods of administering a substance like snorting, shooting, or plugging.
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