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Offlinewillowmp
Medical Psychedelic Mushrooms
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Registered: 07/25/08
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Re: OPANA [Re: Smokeage]
    #14543199 - 05/31/11 10:42 PM (12 years, 7 months ago)

My opiate tolerance fucks me over.

It is really kinda gay. I have a natural tolerance to opiates, so it obviously takes more for me to get high off them. The first time I touched OC I had practically no tolerance from usage, and I snorted 60mg of oxy, and puked the next day.

The problem with having the natural tolerance is that I have issues with nausea. I think it is because I haven't built up the tolerance. Like normally the nausea tends to go away as people use it more and more, but it isn't a super big deal because you can escalate your dose as your tolerance rises. It feels like my tolerance was already jacked up to begin with, causing me to feel nauseous every time, because of the high dose.


Well this was off topic, but does that sound logical?


On topic, how does Opana compare in feel to dillies?


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"Fuck it too much Im outta wittbhjkhbhkjsrglhkrgl g I DEE JEUD."
-Because it made sense on xanax and booze...


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InvisibleSmokeage
arbitrary
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Registered: 08/31/10
Posts: 49
Re: OPANA [Re: willowmp]
    #14543305 - 05/31/11 11:03 PM (12 years, 7 months ago)

That sucks man, I'm thankful I don't have any natural tolerances :cool:.

For me, comparing Opana and Dillys, is kind of like comparing Vicodin and oxy. Dilaudid is more euphoric and less sedating where as the Opana is heavier on the nod, ehh explaining highs isn't my best skill haha.

You just have to try it yourself, everyone reacts differently to everything, but it's a fantastic opiate I can guarantee you that :crazy2:


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InvisibleSmokeage
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Re: OPANA [Re: Smokeage]
    #14543317 - 05/31/11 11:05 PM (12 years, 7 months ago)

Im about to blow me 10mg more and go on a nice little bike ride in the dark of night :cool: I love cruising on opiates


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Invisibleopenmind
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Registered: 08/03/07
Posts: 13,866
Re: OPANA [Re: Smokeage]
    #14543382 - 05/31/11 11:18 PM (12 years, 7 months ago)

Quote:

Smokeage said:
...For me, comparing Opana and Dillys, is kind of like comparing Vicodin and oxy. Dilaudid is more euphoric and less sedating where as the Opana is heavier on the nod....






I would agree with this....And it does make sense as once in your body they are metabolized into a more potent opioid, as follows...


Hydrocodone (Vicoden) ----> Hydromorphone (Dilaudid)


Oxycodone (OC)-----> Oxymorphone (opana)



This is why it is tricky using enzyme inhibitors to potentiate some opiates. If you inhibit the enzyme that metabolizes the opiate into a more potent opioid, in theory you will have prolonged but somewhat diminished effects as the half life is increased but the change into the more potent opiate is more subtle. I would say this stands correct for Oxycodone and Hydrocodone.




:stoner:


.

.


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Invisibleopenmind
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Re: OPANA [Re: Smokeage]
    #14543395 - 05/31/11 11:22 PM (12 years, 7 months ago)

Quote:

Smokeage said:
Im about to blow me 10mg more and go on a nice little bike ride in the dark of night :cool: I love cruising on opiates






Nice...Night time bike rides are incredible whilst zooted from opiates especially during warm summer nights, the wind feels amazing. Many times I rode several miles across town from my friends house after blowing opana. I actually get a HUGE stamina & energy boost from opiates.



:stoner:


.


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InvisibleSmokeage
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Re: OPANA [Re: openmind]
    #14543656 - 06/01/11 12:12 AM (12 years, 7 months ago)

Quote:

openmind said:
Quote:

Smokeage said:
Im about to blow me 10mg more and go on a nice little bike ride in the dark of night :cool: I love cruising on opiates






Nice...Night time bike rides are incredible whilst zooted from opiates especially during warm summer nights, the wind feels amazing. Many times I rode several miles across town from my friends house after blowing opana. I actually get a HUGE stamina & energy boost from opiates.



:stoner:


.




just got back from a short ride. I fully agree with you there buddy, I love night riding  :awegrow:

Here is some music I enjoy thumpin when im groovin on opies. . . perhaps y'all can share some tunes you like to jam while your floating  :headbanger:




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InvisibleEminence
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Registered: 07/25/10
Posts: 16,623
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Re: OPANA [Re: Smokeage]
    #14544022 - 06/01/11 01:52 AM (12 years, 7 months ago)

I fucking love Opana. Love it. Best opiate ever.


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InvisibleAbuse
end of the line


Registered: 08/08/08
Posts: 6,039
Re: OPANA [Re: Smokeage]
    #14544148 - 06/01/11 02:44 AM (12 years, 7 months ago)

never had the privelage of trying dialudid


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Offlines240779
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Registered: 12/07/10
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Re: OPANA [Re: Smokeage]
    #14544486 - 06/01/11 06:11 AM (12 years, 7 months ago)

In my opinion oxycodone and hydrocodone are the two best opiates and are on par with each other. Why? Because they have exceptionally high oral bioavailabilities: about 80% from what I understand. I don't want to fuck around with other, ridiculous methods of administering a substance like snorting, shooting, or plugging.


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