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Legend
RIP Sasha



Registered: 03/29/10
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pros and cons of marijuana
#14533874 - 05/30/11 12:09 AM (12 years, 9 months ago) |
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what are the pros and cons of marijuana in your opinion? but i mean come on, are there really any cons?
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Le_Canard
The Duk Abides


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Re: pros and cons of marijuana [Re: Legend]
#14533886 - 05/30/11 12:11 AM (12 years, 9 months ago) |
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Pro: It's very mild, relaxing and fun. Cons: It's somewhat mildly addicting with regular use, it's very amotivational, and you can get burnt-out on it.
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I_was_the_walrus
eggshells



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Re: pros and cons of marijuana [Re: Legend]
#14533899 - 05/30/11 12:14 AM (12 years, 9 months ago) |
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For me, yes. It makes me tired, lazy and spacey as fuck.
Its good when Im going to bed. Ive got things to do in the day though. Things that require alertness, concentration, a clear head and 100% focus. I really dont have the time to sit around and stare blankly at the tv. I know its not like this for everybody, buuut for me it is.
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Le_Canard
The Duk Abides


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Yes, weed should be for in the evening for when you're through with the day's chores to relax with and help unwind you, like some do with a cocktail in the evening.
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AlmostAsCoolAs


Registered: 11/14/09
Posts: 7,215
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Re: pros and cons of marijuana [Re: Legend]
#14533905 - 05/30/11 12:16 AM (12 years, 9 months ago) |
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There aren't any negative aspects for me since I only use it at night.
Pros are obvious.
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Learyfan
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Re: pros and cons of marijuana [Re: Legend] 1
#14533914 - 05/30/11 12:19 AM (12 years, 9 months ago) |
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The biggest con is that you could become an ex-con.
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gzuf
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Registered: 07/13/09
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Smoking is inherently bad for you.
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Beanhead
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I smoke everyday, I really like it.
Pros: You are more relaxed, able to fall asleep earlier, motivated, able to endure more physical labour , able to eat more which is good because i'm very skinny anyway. Supposedly it's neurological protective aswell but I don't have too much references about that other then a few MDMA studies. It is relatively safe although I do believe you can die from it if you have preconditioned heart injuries, high blood pressure or psychocological problems combined with all the cannabinoïds... It's probably not a good idea then.
Cons: After smoking such a long time you fall under the so called "baseline" , I can be pretty grumpy without. Other then that eating and sleeping is a no go the first few weeks when I don't smoke 
http://neuro.cjb.net/content/20/7/2470.full
**Nora Laaris et. al., "Δ9-tetrahydrocannabinol is a full agonist at CB1 receptors on GABA neuron axon terminals in the hippocampus." Neuropharmacology, Vol. 59, No. 1-2, 121-127. 2010.[
**A. Hoffman, "Mechanisms of Cannabinoid Inhibition of GABA-A Synaptic Transmission in the Hippocampus." J. Neurosci., 20(7):2470-2479. 2000.
Marijuana causes a physiological reaction that causes anxiety.
Depression of growth hormone and cortisol response to insulin-induced hypoglycemia after prolonged oral delta-9-tetrahydrocannabinol administration in man.
Six hospitalized volunteer male subjects were given insulin, 0.15 U/kg, before and after 14 days of administration of delta-9-tetrahydrocannabinol (THC) at a dose of 210 mg/day. A diminished maximal serum human growth hormone (GH) increase followed the prolonged THC ingestion. The mean maximal GH response was: 52.6 ng/ml /- 8.7 ( /-SE) before THC and 18.8 ng/ml /- 6.7 ( /-SE) during THC, P less than 0.01; corresponding cortisol responses were 20.1 mug/dl /- 3.0 before THC and 10.0 mug/dl /- 1.1 during THC, P less than 0.05. The data suggest suppression of the hypothalamic-pituitary axis after prolonged high dose THC use. This is consistent with other reported endocrine effects of marijuana in man.
Gamma-aminobutyric acid B receptor 1 mediates behavior-impairing actions of alcohol in Drosophila: adult RNA interference and pharmacological evidence.
Department of Psychiatry, Psychiatric Institute, University of Illinois, Chicago, IL 60612, USA.
In addition to their physiological function, metabotropic receptors for neurotransmitter gamma-aminobutyric acid (GABA), the GABA(B) receptors, may play a role in the behavioral actions of addictive compounds. Recently, GABA(B) receptors were cloned in fruit flies (Drosophila melanogaster), indicating that the advantages of this experimental model could be applied to GABA(B) receptor research. RNA interference (RNAi) is an endogenous process triggered by double-stranded RNA and is being used as a tool for functional gene silencing and functional genomics. Here we show how cell-nonautonomous RNAi can be induced in adult fruit flies to silence a subtype of GABA(B) receptors, GABA(B)R1, and how RNAi combined with pharmacobehavioral techniques (including intraabdominal injections of active compounds and a computer-assisted quantification of behavior) can be used to functionally characterize these receptors. We observed that injection of double-stranded RNA complementary to GABA(B)R1 into adult Drosophila selectively destroys GABA(B)R1 mRNA and attenuates the behavioral actions of the GABA(B) agonist, 3-aminopropyl-(methyl)phosphinic acid. Moreover, both GABA(B)R1 RNAi and the GABA(B) antagonist CGP 54626 reduced the behavior-impairing effects of ethanol, suggesting a putative role for the Drosophila GABA(B) receptors in alcohol's mechanism of action. The Drosophila model we have developed can be used for further in vivo functional characterization of GABA(B) receptor subunits and their involvement in the molecular and systemic actions of addictive substances.
Quote:
mellowparty said:
Quote:
2Cents said: This thread is completely and utterly stupid.
Still beats your post
As long as it triggers a reward pathway the user will seek more weed which has some elements of addiction. The constant agonisation of CB1R on GABAergic neurons will in turn lead to the endocytosis and destruction of cannabinoid receptors. This means less dopamine because double inhibition will not occur. And less dopamine means 
Everybody can live fine without weed. This doesn't mean it totally non-addictive. Just because you dont start puking and shivering doesnt mean there is no addiction involved.
Great post by mellowparty...
http://www.shroomery.org/forums/showflat.php/Number/8327648/fpart/1/vc/1 You can find some good information and angry people discussing it there
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AlmostAsCoolAs


Registered: 11/14/09
Posts: 7,215
Loc: California
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Re: pros and cons of marijuana [Re: gzuf]
#14533935 - 05/30/11 12:26 AM (12 years, 9 months ago) |
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I'll be dead before smoking causes any noticeable health issues. Then again I keep my tolerance low so I don't smoke nearly as much as most people on here.
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s240779


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Re: pros and cons of marijuana [Re: gzuf]
#14533936 - 05/30/11 12:26 AM (12 years, 9 months ago) |
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Quote:
gzuf said: Smoking is inherently bad for you.
Smoking natural, organic weed is so minor. Very little substance is smoked (as compared to smoking a pack of cigarettes a day) and the smoke produced from marijuana is not that harsh. And if you dilute your hits with air, it's like nothing.
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IamMatt
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Re: pros and cons of marijuana [Re: Legend]
#14533942 - 05/30/11 12:27 AM (12 years, 9 months ago) |
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lulz. My parents and uncle thinks it gives you cancer.
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gzuf
٩(̾๏̮̮̃̾๏̃̾)۶



Registered: 07/13/09
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Re: pros and cons of marijuana [Re: IamMatt]
#14533957 - 05/30/11 12:31 AM (12 years, 9 months ago) |
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Still, I mean, you are inhaling smoke in to your lungs. I don't doubt it's not as bad as cigarettes but it's still smoking. Especially if you smoke multiple bowls a day.
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I_was_the_walrus
eggshells



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Re: pros and cons of marijuana [Re: gzuf]
#14533968 - 05/30/11 12:35 AM (12 years, 9 months ago) |
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Pretty much. Some things are worse for you, but the point remains the same. Smoke does not belong in your lungs.
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gzuf
٩(̾๏̮̮̃̾๏̃̾)۶



Registered: 07/13/09
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People who smoke res are doing more damage to their lungs than a cigarette, in my opinion. That shit is filthy.
I just smoked some
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uninc4life2010
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Re: pros and cons of marijuana [Re: gzuf]
#14533982 - 05/30/11 12:39 AM (12 years, 9 months ago) |
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I personally never enjoyed the effect of marijuana. I always felt that it made me feel down and depressed, VERY paranoid, heavy dry mouth, and it sometimes gave me a feeling of worthlessness. I also had an unusually low tolerance, so many of the effects I described were greatly exacerbated. I have many friend that smoke daily, and I do not doubt that many people benefit greatly from the medical and recreational effect of pot. But for me, it never worked. I smoked off and on for 4 years, but I haven't smoked in about a year and 3 months.
As for the health effects, I never smoked regularly enough to notice any.
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Legend
RIP Sasha



Registered: 03/29/10
Posts: 28,336
Loc: TX
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Marijuana smoke does not go deep into the lungs like tobacco does. Plus THC and other cannabinoids counteract the carcinogens.
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No sympathy for the devil, keep that in mind. [url=]Buy the ticket, take the ride. [/url]Are you lost?
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Satyapriya



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cons: anxiety (for me at least), paranoia, higher awareness of chronic pain, you can get burnt out easily, spaciness...
pros: fantastic tool for self-therapy, great for writing music, higher awareness of emotions (for me at least), more enjoyable/memorable sex, clearer thinking, can be ingested rather than smoked, non-addictive (in my case)...etc
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Le_Canard
The Duk Abides


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Quote:
uninc4life2010 said: I personally never enjoyed the effect of marijuana. I always felt that it made me feel down and depressed, VERY paranoid, heavy dry mouth, and it sometimes gave me a feeling of worthlessness. I also had an unusually low tolerance, so many of the effects I described were greatly exacerbated. I have many friend that smoke daily, and I do not doubt that many people benefit greatly from the medical and recreational effect of pot. But for me, it never worked. I smoked off and on for 4 years, but I haven't smoked in about a year and 3 months.
Well, it's definitely not for everyone.
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the human abstract
malaka the werewolf



Registered: 11/30/09
Posts: 8,817
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Re: pros and cons of marijuana [Re: Le_Canard]
#14534020 - 05/30/11 12:51 AM (12 years, 9 months ago) |
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a huge con of "street" marijuana is the plants arent cared for and its about money
i dont even want to pay the 350oz bc there are places to get it cheaper and the plants are grown for medical uses
but this isnt about street weed so
weed is from the earth. god put this here for me and you
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IamMatt
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Re: pros and cons of marijuana [Re: gzuf]
#14534023 - 05/30/11 12:51 AM (12 years, 9 months ago) |
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I'm not saying it's not bad for your lungs but I don't think it gives you cancer.
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