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OfflineDubshroomer
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Registered: 10/28/10
Posts: 54
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Last seen: 11 years, 10 months
MDMA effects diminished by St Johns Wort?
    #14376098 - 04/30/11 04:32 AM (12 years, 9 months ago)

I have only taken MDMA 2 times previous.  The first was with 100mg and was an amazing experience.  I haven't tried MDMA again for over 18 months.

I've been taking St Johns Wort for about 4-6 weeks now on an almost daily basis.  I sometimes take 5-HTP as well.  I'm male and a big guy (6'2" 260lbs).  Today I got 1g of crystalline MDMA and it Mecke reagent tested green>purple>black in about 5 seconds.  Earlier, I took 900mg SJW and 100mg 5-HTP

+0:00 - Ate 100mg MDMA
+0:25 - Ate 50mg
+1:00 - Ate 50mg

No real effects through the course of the night.  I was in a good mood and felt good but definitely not rolling.

+5:00 - Insufflated 100mg
+6:00 - No effects felt.

I didn't even think that the SJW and 5-HTP could be interfering but after searching online I found differing opinions (of course).  I do now know that SJW and MDMA can potentially cause seratonin syndrome, but will it diminish or eliminate the high from MDMA?  How long will I need for my system to "reset" if I discontinue the SJW?  I'd really like to try again in about 3 days because my girlfriend is visiting and it would be her first time, but I don't want to waste any more MDMA or possibly harm my brain.


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As to the American tradition of non-meddling, Anarchism asks that it be carried down to the individual himself. It demands no jealous barrier of isolation; it knows that such isolation is undesirable and impossible; but it teaches that by all men's strictly minding their own business, a fluid society, freely adapting itself to mutual needs, wherein all the world shall belong to all men...then may we hope to see a resurrection of that proud spirit of our fathers which put the simple dignity of Man above the gauds of wealth and class, and held that to be an American was greater than to be a king. In that day there shall be neither kings nor Americans — only Men ; over the whole earth, MEN. - de Cleyre "Anarchism and American Traditions"

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Offlinemr_minds_eye
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Registered: 01/22/02
Posts: 1,948
Loc: Samsara
Last seen: 11 years, 1 month
Re: MDMA effects diminished by St Johns Wort? [Re: Dubshroomer]
    #14376704 - 04/30/11 09:49 AM (12 years, 9 months ago)

5-HTP wouldn't interfere. In fact people take this before after and during a MDMA session to roll harder, longer, and to not feel all janked out the next day. I have tripped while on antidepressants when I was younger and it changed the nature of things for sure. I mean MDMA acts on the same neurotransmitter that SSRI's, like St. Johns Wort do. If you really need the St. johns Wort just stick with it though. Feeling ok most of the time is better than feeling great for 4-6hrs imo.


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Our quest for discovery fuels our creativity in all fields, not just science. If we reached the end of the line, the human spirit would shrivel and die. But I don't think we will ever stand still: we shall increase in complexity, if not in depth, and shall always be the center on an expanding horizon of possibilities.
-Stephen Hawking

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