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OfflineROFL_my_ WAFFLE


Registered: 08/28/09
Posts: 3,984
Loc: Florida Flag
Last seen: 3 years, 6 months
Re: New study on psilocybin [Re: BothHands]
    #14258382 - 04/08/11 12:36 PM (12 years, 10 months ago)

Quote:

BothHands said:
:popcorn:




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InvisibleSamuel L Jackson
Bad Motherfucker
Male

Registered: 12/10/09
Posts: 8,395
Re: New study on psilocybin [Re: ROFL_my_ WAFFLE]
    #14258411 - 04/08/11 12:43 PM (12 years, 10 months ago)

i personally think we shouldnt get our hopes up because your consciousness is expanded when you take these kinds of drugs!

society cant allow that, if you want your depression to go away you have to minimalize your feelings and shrink yourself into being a shell of a human that cant feel emotion!


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Invisiblebadchad
Mad Scientist

Registered: 03/02/05 Happy 19th Shroomiversary!
Posts: 13,374
Re: New study on psilocybin [Re: Samuel L Jackson]
    #14258509 - 04/08/11 01:09 PM (12 years, 10 months ago)

And the fact that this was an fMRI study.

I don't think they had any assessments directly relevant to depression actually performed.


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...the whole experience is (and is as) a profound piece of knowledge.  It is an indellible experience; it is forever known.  I have known myself in a way I doubt I would have ever occurred except as it did.

Smith, P.  Bull. Menninger Clinic (1959) 23:20-27; p. 27.

...most subjects find the experience valuable, some find it frightening, and many say that is it uniquely lovely.

Osmond, H.  Annals, NY Acad Science (1957) 66:418-434; p.436

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InvisibleDr. McNinja
Ghost in the Machine
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Folding@home Statistics
Registered: 01/17/10
Posts: 120
Loc: New England Flag
Re: New study on psilocybin [Re: badchad]
    #14258616 - 04/08/11 01:42 PM (12 years, 10 months ago)

I'm not surprised that the effects of Psilocybin are related to decreased circulation in the brain - Holotropic breathing works by a similar mechanism, though not by chemical means and without any effect on your serotonin receptors. Decreased communication between portions of the brain would explain why synesthesia often occurs.

Quote:

Patlal said:
HA!

I always had that hunch that the spiritual crap that comes from mushroom isn't an increase in brain activity!

I always was a strong believer that the sober mind is more powerful than a mind under the efect of something!

So it is true... that mind expansion, spiritual awakening is all bullshit!




Did you bother to read even that very short summary of the study that OP provided Patlal?

One of the researchers interviewed for the New Scientist article concludes that "...because psilocybin increases the expression of genes and signalling proteins associated with nerve growth and connectivity" it may increase long-term neuroplasticity. We've been hearing the same thing from MAPS for years. If that's not "Mind expansion" then what is? Your skull isn't going to get any larger you dummy, it's about increased neural activity. 

:huxleyfacepalm:


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Offline28064212
Special Agent Dale Cooper
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Registered: 01/15/11
Posts: 12,115
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Re: New study on psilocybin [Re: ACTG]
    #14258647 - 04/08/11 01:47 PM (12 years, 10 months ago)

I don't think it's fair to say psycehdelics cause an improvement or decrease in healthy brain function, it simply changes it. Allows you to get lost in order to find yourself. :sun:


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InvisibleDr. McNinja
Ghost in the Machine
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Registered: 01/17/10
Posts: 120
Loc: New England Flag
Re: New study on psilocybin [Re: 28064212]
    #14258769 - 04/08/11 02:12 PM (12 years, 10 months ago)

If it increases long-term neuroplasticity (the ability of your brain to rewire itself, essentially) then that is a definite increase in healthy brain function. What they're saying in this article is that the short-term effects of psilocybin include reduced blood flow and less communication between certain areas of the brain...which they are surprised occur DURING a psychedelic trip which has always been assumed to involve increased activity. Makes sense to me though, after all Meditative states can be very psychedelic and they also involve less sensory function but stimulate neuron growth in the long run.

Sorry to have called you a dummy Patlal, no need for me to be rude.

I get where you're coming from on sobriety being an asset but this article does nothing to support the second half of your statement and I don't believe you checked in the first place which is bad form in a thread specifically about a scientific study.


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OfflineRocker232
Stranger


Registered: 10/17/08
Posts: 6,631
Last seen: 12 years, 6 months
Re: New study on psilocybin [Re: 28064212]
    #14258828 - 04/08/11 02:24 PM (12 years, 10 months ago)

Quote:

28064212 said:
I don't think it's fair to say psycehdelics cause an improvement or decrease in healthy brain function, it simply changes it. Allows you to get lost in order to find yourself. :sun:




I'd have to disagree. Being someone who suffers from depression and OCD I can say without a doubt that in these two cases there is most definitely a link between lessening their grip on my mind and eating mushrooms. If you've been down those two roads you can appreciate the relief that this medicine can give.

:heart: I need me some mushrooms soon


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With Allure I Look to the Sky With Awakened Eyes

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OfflinePatlal
You ask too many questions
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Registered: 10/09/10
Posts: 44,818
Loc: Ottawa Flag
Last seen: 14 hours, 26 minutes
Re: New study on psilocybin [Re: Dr. McNinja]
    #14258863 - 04/08/11 02:31 PM (12 years, 10 months ago)

wow, gots lots of comment from my comment.

The real truth in all of this is that the scientist are now slightly less clueless.

@Overmind I'm not offended by your comment

Everything about psilocybin (perhaps 90% of it) is all speculation. a lot more studies needs to be made before any of us can actually make a valid slightly truthful comment on the matter.

I'm also willing to bet that most of you (if not all) don't even know how to read an MRI... me included.

Let the scientist work.. perhaps we will have a plausible answer in our lifetime.


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Offline28064212
Special Agent Dale Cooper
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Registered: 01/15/11
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Re: New study on psilocybin [Re: Rocker232]
    #14259865 - 04/08/11 05:38 PM (12 years, 10 months ago)

Quote:

Rocker232 said:
Quote:

28064212 said:
I don't think it's fair to say psycehdelics cause an improvement or decrease in healthy brain function, it simply changes it. Allows you to get lost in order to find yourself. :sun:




I'd have to disagree. Being someone who suffers from depression and OCD I can say without a doubt that in these two cases there is most definitely a link between lessening their grip on my mind and eating mushrooms. If you've been down those two roads you can appreciate the relief that this medicine can give.

:heart: I need me some mushrooms soon




I also suffer from OCD, BIG TIME!
:hi5: OCD club!
:lol:

But psychedelics definitely hope my OCD too.
I can see how they can cut off communication between parts of the brain, but that's not a bad thing.


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OfflineGGTBod
Bod
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Registered: 11/19/10
Posts: 2,191
Loc: 55 degrees north England
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Re: New study on psilocybin [Re: 28064212]
    #14260103 - 04/08/11 06:26 PM (12 years, 10 months ago)

It makes perfect sense the reduced blood flow corresponds directly with the ego death point of the experience, it doesn't take a nuerosurgeon to put 2 and 2 toget5her here especially if you have taken large doses of psilocybin before.

The human brain is basically a huge filtering mechanisms that allow us to focus our senses to perceive our world and in a way that best suits how we need to interact in it to survive, the reduced blood flow (ego death) often feels like an enhancement to brain function as the brain is now active without the clouded, biased filtering perspective of the ego/personailty with all the pre concieved perceptions that we have all built up in our lives to be a part of our social group, the social contract we have been subconciously entered into, free from this to some is an amazing opening of mind compared to their previous awareness.

I posted a great documentary that was being made as this study was happening and the bloke in the study took a nice dose and went in the MRI machine

Here is the thread


here is the international link to download the documentary

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Invisiblebuckwheat
Cynically Insane


Registered: 12/09/02
Posts: 11,179
Loc: Not Enough Characters to ...
Re: New study on psilocybin [Re: GGTBod]
    #14260156 - 04/08/11 06:38 PM (12 years, 10 months ago)

Great explanation.

Pure speculation.I wonder if the reduced communication in the brain is even greater under DMT. It could be not that DMT is released during death. But the "brain shut down" process produces a similar lack of communication.

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Offlinea711slurpee
[do_Ob]
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Registered: 06/27/10
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Re: New study on psilocybin [Re: buckwheat]
    #14260231 - 04/08/11 06:56 PM (12 years, 10 months ago)

Awesome article... I find the physical chemistry our bodies undergo unbelievably fascinating!

I always feel amazing and never the same after a trip... like my perspective has been expanded and changed — I LOVE IT.

Thanks for sharing the article!


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—every moment of your life is a chance to get it right—

[ I am for mental extensions ]

—always searching for answers—

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OfflineGGTBod
Bod
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Registered: 11/19/10
Posts: 2,191
Loc: 55 degrees north England
Last seen: 5 days, 9 hours
Re: New study on psilocybin [Re: buckwheat]
    #14260243 - 04/08/11 07:00 PM (12 years, 10 months ago)

Definitely total speculation, it makes sense that a reduced blood flow to any part of the brain would change our perceptions essentially change how it filters the input from the senses (to be descriptive instead of hippy cliche). The experts believe the hypothalamus region (where the blood flow is reduced)is where our sense of self is located obviously all based on current studies and our interpretation of the data, i'm sure if the people interpreting the data have experienced an ego death via psilocybin they will have already come to this conclusion/belief, its a whole different story regarding what gets put in the official report to the benefactors and the public.

More studies should be done on all psychedelics there are many benefits they have to offer society in general as well as for the individual and a greater understanding will help avoid the "disasters" and emergency room drama ego death experiences we have all heard about.

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InvisibleJanamil


Registered: 08/01/09
Posts: 1,699
Re: New study on psilocybin [Re: GGTBod]
    #14263260 - 04/09/11 02:20 PM (12 years, 10 months ago)

Im guessing it doesn't reduce bloodflow, the brain just stops asking for it.

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