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Offlinewithoutawire
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Registered: 08/16/09
Posts: 11,384
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Re: Promethazine/codeine cough syrup [Re: Gzaajhom]
    #14200339 - 03/28/11 09:04 PM (12 years, 10 months ago)

Hydrocodone is a weak opioid just like codeine, so a average dose of promethazine would put you in the 10%-20% less milligrams of opioid.

180mg codeine = 9mg morphine = 4.5mg oxycodone.

You need a lot more codeine than you think most of the time.

Some people have higher tolerances. Mine always climbed in plateaus in semi weekly-monthly periods(at first). At first 15mg hydrocodone got me high as shit. Eventually I had to snort 23-25 roxi's each time I got high (every 7 hours) to get an oxycodone nod/buzz.


Tolerance with opiates is a huge mystery. Opioids are one of the oldest medications and we still don't know most things about them.


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OfflineBothHands
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Registered: 10/28/09
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Re: Promethazine/codeine cough syrup [Re: amilibertine]
    #14200439 - 03/28/11 09:17 PM (12 years, 10 months ago)

Quote:

Cynosure said:
Quote:

BothHands said:
Quote:

FurthurHead said:
to be honest i cant take vicodin or hydrocodons because they always make me super nauses and sick. but with prometh/codeine i can drink it and wont ever get sick like those others make me feel.




Take promethazine with your hydrocodone and you won't puke.  Hell, even dramamine would work.




Be careful prescribing that, Dr. BothHands.

Promethazine potentiates most opiates, this could easily cause someone to overdose on what they considered to be a fair dosage.




I assumed that since he wasn't an addict dosing to his limits, it wouldn't be an issue.  But you're right, other users do view these forums, and it should be pointed out that if you're dosing to the edge of your limits, adding other CNS depressants could be dangerous.  But I was personally prescribed promethazine with vicodin so I could keep it down.  20mg hydrocodone + 10mg promethazine won't kill you.  Not unless you're 4 feet tall and 75 pounds or something.

Quote:

amilibertine said:
Vomiting can be a symptom of an allergy.  My point is that 5mg hydrocodone is a very small amount and even someone with no tolerance should be able to take that amount without any unpleasentness. 

I'm not you though and I'm not trying to be a doctor.  Just saying that puking from one vicodin is like puking from one beer. 

I'm actually not sure what you are saying the reason for the vomiting is?  If your not allergic and you puke before it crosses the blood-brain barrier what do you think the cause is? 

Very strange.




The vomiting is caused by the action of opiates on the chemotactic trigger zone of the brain.  This particular part of the brain can be more sensitive to stimulation in certain people.

I never said that I puked before the hydrocodone crossed the BBB, I said I puked before the dose was high enough to cause intoxication.  5mg doesn't cause intoxication, whether or not I puke.


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InvisibleGzaajhom
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Registered: 12/11/10
Posts: 183
Loc: USA
Re: Promethazine/codeine cough syrup [Re: withoutawire]
    #14200488 - 03/28/11 09:24 PM (12 years, 10 months ago)

Quote:

withoutawire said:
Hydrocodone is a weak opioid just like codeine, so a average dose of promethazine would put you in the 10%-20% less milligrams of opioid.

180mg codeine = 9mg morphine = 4.5mg oxycodone.



According to the opioid comparison article on wiki, 180mg codeine = 18mg morphine = 9mg oxy. That said, 27mg oxy is a moderate dose, yet 540mg (the "equivalent" amount) codeine is a dangerously high dose. I dont know, I'm just a guy who posts pictures of food.


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