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OfflineIma TrooperS
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Snorting codeine?
    #14138262 - 03/17/11 06:02 PM (12 years, 10 months ago)

So I threw my lower back out at the gym today, and I'm back at the house and my brother's ex-girlfriend is over here. They call me into the kitchen and there's a decently sized line about <==================> and they said its about 5mgs of a codeine pill. And they want me to snort it, and I'm like...I think it has better bioavailability if you just eat it. And she says she knows what she's doing, so I'm just like "what the fuck ever, its free."

So I snort it. I felt stupid snorting a line that size with only 5mgs in it, (probably 90% filler and binder) but like I said, it was free and my back hurts like a motherfucker. Did I make the right choice in snorting or should I have eaten it?


BTW it does seem to be making my back feel better, its only been about 5 mins...


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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Offlines240779
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138274 - 03/17/11 06:04 PM (12 years, 10 months ago)

You did eat it. Your nasal things can only absorb a very small amount (plus the binders and fillers inhibited nasal absorption). It dripped down your throat.


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OfflineIma TrooperS
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Re: Snorting codeine? [Re: s240779]
    #14138294 - 03/17/11 06:06 PM (12 years, 10 months ago)

Yeah I know. Thats why I feel fucking stupid snorting it in the first place. I know my drugs, and I know that pills are meant to be swallowed 9 times out of 10. Stupid little underage motherfuckers thinkin they're bad because they snort everygoddamnthing. My back hurts and my tolerance for bullshit is so motherfucking low its almost nonexistant.


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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Offlines240779
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138340 - 03/17/11 06:13 PM (12 years, 10 months ago)

Quote:

Ima Trooper said:
9 times out of 10.




One example of a pill that should be snorted is oxymorphone. Oxymorphone has a very poor oral bioavailability. And snorting oxymorphone will work because it's so potent.


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OfflineIma TrooperS
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Re: Snorting codeine? [Re: s240779]
    #14138356 - 03/17/11 06:15 PM (12 years, 10 months ago)

Right, I know A FEW pills have good nasal bioavailability, but most its better if you just swallow it. Whatever. God I hate everybody right now.


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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InvisibleHeavyToilet
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138433 - 03/17/11 06:27 PM (12 years, 10 months ago)

For 5mgs? Wow.

I've eaten 3-4 T3s (which each contain 30mg of codeine, so 90-120mg total) a number of times, and it usually isn't even that strong (I don't take more than that because all the disgusting acetaminophen makes me feel like shit... so with more I do a cold-water extraction).

So yeah, that was completely pointless. :rockon:


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OfflineIma TrooperS
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Re: Snorting codeine? [Re: HeavyToilet]
    #14138445 - 03/17/11 06:29 PM (12 years, 10 months ago)

Well I feel a little different, but I also have a very low tolerance to opiates. One perc 7.5mg will fuck me up and I can totally feel 5mgs, especially with a drink or two.


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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OfflineIma TrooperS
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138520 - 03/17/11 06:40 PM (12 years, 10 months ago)

God DAMN this drip is disgusting. I haven't snorted anything in a long ass time, I forgot what it tasted like. MEH


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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OfflineBeverageFace
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138618 - 03/17/11 06:52 PM (12 years, 10 months ago)

5mg codeine is nothing, and needs to be passed through your liver to become morphine. Might be placebo.
.
Even 30mg codeine in a t3 is barely noticeable if at all.

sounds like a bad snort.


Edited by BeverageFace (03/17/11 06:53 PM)


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Offlineegodeathflux
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Re: Snorting codeine? [Re: BeverageFace]
    #14138667 - 03/17/11 06:58 PM (12 years, 10 months ago)

I ate 120mg of codeine phosphate with 15mg diazepam to potentiate it about 2 hours ago, don't really feel much at all. I would love to live in a world where 5mg codeine did anything..:shrug:


--------------------

"Atrophic interludes weave through my life far too often, for me to fight the biggest enemies"




"Standing on the corner of 5th and Vermouth"



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OfflineIma TrooperS
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Re: Snorting codeine? [Re: egodeathflux]
    #14138703 - 03/17/11 07:03 PM (12 years, 10 months ago)

I don't *think* its placebo. But then again, I wouldn't know either since its "placebo". Lol oh well. I definitely feel different. Slower and duller. And whatever got into me, its being potentiated by a beer and two Aleve, lol.


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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Offlinenice1
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138724 - 03/17/11 07:06 PM (12 years, 10 months ago)

Codiene is not much fun.  I heard its OK if you do hundreds of mgs and can stay awake...


I had them for my back pain and 90mg would knock me out for the whole day asleep so not really my idea of fun.

Oxycontin, smack or pods = :thumbup:


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Offlineegodeathflux
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Re: Snorting codeine? [Re: nice1]
    #14138733 - 03/17/11 07:07 PM (12 years, 10 months ago)

:tee:


--------------------

"Atrophic interludes weave through my life far too often, for me to fight the biggest enemies"




"Standing on the corner of 5th and Vermouth"



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OfflineIma TrooperS
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Re: Snorting codeine? [Re: nice1]
    #14138746 - 03/17/11 07:09 PM (12 years, 10 months ago)

Quote:

nice1 said:
Codiene is not much fun.  I heard its OK if you do hundreds of mgs and can stay awake...


I had them for my back pain and 90mg would knock me out for the whole day asleep so not really my idea of fun.

Oxycontin, smack or pods = :thumbup:




I can't even do opiates for fun anymore. I get so nauseous after taking even one 7.5 perc that its just not even worth it. All my drugs turned on me. :sad:


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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OfflineBeanhead
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138889 - 03/17/11 07:33 PM (12 years, 10 months ago)

I ate 200mg of codeine just moments ago. Last fun with opiates was in the summer with a few poppies/opium

Are you even feeling anything from the 5mg? Any pain-relief?

AND CMON TROOPER, DRUGS TURNING ON YOU!? YOU A TROOPER OR WHAT


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OfflineIma TrooperS
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Re: Snorting codeine? [Re: Beanhead]
    #14138931 - 03/17/11 07:38 PM (12 years, 10 months ago)

lol yeah I feel a little, but it also feels like its starting to wear off. You're right though, the least I could do is have some whiskey. :thumbup:


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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OfflineHajnal
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138959 - 03/17/11 07:41 PM (12 years, 10 months ago)

To be honest I just like snorting shit :shrug:

May not always be the best method of ingestion, however I've always snorted for recreational purposes, so I'm going to bet you guys are right in saying that for legitimate use it probably is better just take orally.


--------------------
Hajnal ['hɒjnɒl] - An elegant mixture of blood and circuitry; sorrow and love fill your systems, like the stars and black holes encompass the ∞.


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OfflineBeanhead
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Re: Snorting codeine? [Re: Ima Trooper]
    #14138960 - 03/17/11 07:41 PM (12 years, 10 months ago)

Hmmmm I had a beer earlier, whiskey sounds A-okay:cheers:

I :feelsverygoodman: right now


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OfflineHajnal
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Re: Snorting codeine? [Re: Beanhead]
    #14139005 - 03/17/11 07:47 PM (12 years, 10 months ago)

Quote:

Beanhead said:
Hmmmm I had a beer earlier, whiskey sounds A-okay:cheers:

I :feelsverygoodman: right now




I'm working on some 44 North! MAn this shit is tasty. Too bad I work at 5:30 am :facepalm:


--------------------
Hajnal ['hɒjnɒl] - An elegant mixture of blood and circuitry; sorrow and love fill your systems, like the stars and black holes encompass the ∞.


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OfflineBothHands
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Re: Snorting codeine? [Re: Ima Trooper]
    #14139016 - 03/17/11 07:49 PM (12 years, 10 months ago)

Codeine is an inactive chemical.  It only becomes active when it's metabolized into morphine by the liver.  If you snort it, it bypasses the liver, and enters your bloodstream completely inactive.  What you're feeling is from swallowing the drip.

Now the inactive codeine will eventually be metabolized to morphine via second pass metabolism, but it'll happen very slowly.  This means that the morphine from the first pass metabolism has already started leaving your system by the time the codeine starts becoming morphine via second pass metabolism.  All in all, it's extremely ineffective.

Codeine and Tramadol need to be eaten.


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OfflineHajnal
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Re: Snorting codeine? [Re: BothHands]
    #14139049 - 03/17/11 07:55 PM (12 years, 10 months ago)

Quote:

BothHands said:
Codeine is an inactive chemical.  It only becomes active when it's metabolized into morphine by the liver.  If you snort it, it bypasses the liver, and enters your bloodstream completely inactive.  What you're feeling is from swallowing the drip.

Now the inactive codeine will eventually be metabolized to morphine via second pass metabolism, but it'll happen very slowly.  This means that the morphine from the first pass metabolism has already started leaving your system by the time the codeine starts becoming morphine via second pass metabolism.  All in all, it's extremely ineffective.

Codeine and Tramadol need to be eaten.




Really? This is good to know; I once in a while run into some from my friend and we've always snorted it. I've always felt it pretty fast, and it was a nice buzz.. Was that a placebo?


--------------------
Hajnal ['hɒjnɒl] - An elegant mixture of blood and circuitry; sorrow and love fill your systems, like the stars and black holes encompass the ∞.


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OfflineBothHands
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Re: Snorting codeine? [Re: Hajnal]
    #14139110 - 03/17/11 08:05 PM (12 years, 10 months ago)

I'm not 100% sure.  It's probably a bit of placebo, and a bit of second pass metabolism, and a bit of drip.  But you should get a higher bioavailability, and a faster onset if you just chew and swallow.  If you don't chew, it needs to dissolve, but it'll still probably come up at the same speed as the insufflated dose, but it'll have a higher BA.


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Re: Snorting codeine? [Re: BothHands]
    #14139125 - 03/17/11 08:07 PM (12 years, 10 months ago)

Thanks good info.

Placebo effect is very strong BTW its completely underestimated in general because people just don't realise the power of the mind / belief.


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OfflineBothHands
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Re: Snorting codeine? [Re: nice1]
    #14139183 - 03/17/11 08:15 PM (12 years, 10 months ago)

Well, it's still very likely that there were some some effects that compounded with the placebo effect.  If you have an extremely full stomach, an insufflated dose might come on faster, but you'll still waste product.  But on an empty stomach, there is absolutely no reason to ever snort codeine.


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Re: Snorting codeine? [Re: BothHands]
    #14139212 - 03/17/11 08:19 PM (12 years, 10 months ago)

Quote:

BothHands said:
Codeine is an inactive chemical.  It only becomes active when it's metabolized into morphine by the liver.  If you snort it, it bypasses the liver, and enters your bloodstream completely inactive.  What you're feeling is from swallowing the drip.

Now the inactive codeine will eventually be metabolized to morphine via second pass metabolism, but it'll happen very slowly.  This means that the morphine from the first pass metabolism has already started leaving your system by the time the codeine starts becoming morphine via second pass metabolism.  All in all, it's extremely ineffective.

Codeine and Tramadol need to be eaten.




You really don't know what you're talking about, do you?


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OfflineIma TrooperS
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Re: Snorting codeine? [Re: BothHands]
    #14139213 - 03/17/11 08:19 PM (12 years, 10 months ago)

Thats what I thought. But my little bro's friend was all "I know what I'm doing" so I snorted it. :facepalm: Oh well.


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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OfflineIma TrooperS
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Re: Snorting codeine? [Re: s240779]
    #14139221 - 03/17/11 08:20 PM (12 years, 10 months ago)

Quote:

superhigh said:



You really don't know what you're talking about, do you?





:confused2:


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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OfflineHajnal
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Re: Snorting codeine? [Re: Ima Trooper]
    #14139232 - 03/17/11 08:22 PM (12 years, 10 months ago)

Quote:

Ima Trooper said:
Quote:

superhigh said:



You really don't know what you're talking about, do you?





:confused2:



Quote:

Ima Trooper said:
Quote:

superhigh said:



You really don't know what you're talking about, do you?





:confused2:




Damnit so which is it? Ah fuck it; erowid it is.


--------------------
Hajnal ['hɒjnɒl] - An elegant mixture of blood and circuitry; sorrow and love fill your systems, like the stars and black holes encompass the ∞.


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OfflineBothHands
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Re: Snorting codeine? [Re: s240779]
    #14139265 - 03/17/11 08:26 PM (12 years, 10 months ago)

Oh?  Enlighten me.


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OfflineIma TrooperS
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Re: Snorting codeine? [Re: Hajnal]
    #14139279 - 03/17/11 08:28 PM (12 years, 10 months ago)

From Erowid:

"Codeine is absorbed quickly from the GI tract and it's first pass through the liver results in very little loss of the drug. This contrasts with morphine in which over 90% of the drug is metabolized in the first pass through the liver resulting in a considerable loss of potency when administered orally. This is why codeine is a common opiate in the relief of pain, the ease of oral administration.

Codeine can be administered by many routes, this includes, SC, IM (intramuscularly), as an enema, and orally."

And: "Codeine is converted to morphine during hapatic metabolism"

I don't know what that is, but its looking better and better for Bothhands...


--------------------
"Its moving of its own accord...and I like that in a shirt!" - Me, tripping.

deCypher said:
Schizophrenia beats dining alone, you know.


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Re: Snorting codeine? [Re: Ima Trooper]
    #14139282 - 03/17/11 08:29 PM (12 years, 10 months ago)

BothHands is asserting that codeine is more effective when it's handled by the liver because it's a prodrug that needs to be converted. Heroin is also a prodrug, which converts to, I believe, morphine, 3-monoacetylmorphine, and 6-monoacetylmorphine. So why is it that heroin has the highest bioavailability when injected and the lowest bioavailability when swallowed?


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OfflineBothHands
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Re: Snorting codeine? [Re: Ima Trooper]
    #14139308 - 03/17/11 08:35 PM (12 years, 10 months ago)

I believe the reason they left out INA is because insufflating codeine can cause massive histamine release in the lungs.  Or at least that's the general consensus on bluelight, but there is no specific source, so it could be untrue.

Insufflation will work, but it will have a slower onset and a lower bioavailability, meaning you're wasting product.


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OfflineBothHands
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Re: Snorting codeine? [Re: s240779]
    #14139317 - 03/17/11 08:37 PM (12 years, 10 months ago)

Quote:

superhigh said:
BothHands is asserting that codeine is more effective when it's handled by the liver because it's a prodrug that needs to be converted. Heroin is also a prodrug, which converts to, I believe, morphine, 3-monoacetylmorphine, and 6-monoacetylmorphine. So why is it that heroin has the highest bioavailability when injected and the lowest bioavailability when swallowed?




A quick google search will answer that question.

Quote:

When taken orally, diacetylmorphine undergoes extensive first-pass metabolism via deacetylation, making it a prodrug for the systemic delivery of morphine.[17] When the drug is injected, however, it avoids this first-pass effect, very rapidly crossing the blood-brain barrier because of the presence of the acetyl groups, which render it much more fat soluble than morphine itself.[18] Once in the brain, it then is deacetylated variously into the inactive 3-monoacetylmorphine and the active 6-monoacetylmorphine (6-MAM),




When taken orally, it's a prodrug for morphine.  The liver turns it into morphine, which makes it almost the same potency as morphine.  But when it's IV'd it skips first pass metabolism, gets into the brain very quickly, and is metabolized into the more powerful chemicals in the brain.

pwnd


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Re: Snorting codeine? [Re: BothHands]
    #14139335 - 03/17/11 08:41 PM (12 years, 10 months ago)

And how do you know codeine isn't converted better via methods other than oral?


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OfflineBothHands
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Re: Snorting codeine? [Re: s240779]
    #14139384 - 03/17/11 08:49 PM (12 years, 10 months ago)

Mind rephrasing your question so that it makes sense?

How do I know second pass metabolism isn't better than first pass? 


Well, they're the same.  They're both liver metabolism.  The only difference is you have to wait longer for second pass.


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Re: Snorting codeine? [Re: Ima Trooper]
    #14139400 - 03/17/11 08:52 PM (12 years, 10 months ago)

You're assuming that codeine has a higher bioavailability when taken orally because you think first pass metabolism works better for it. You can't back that up.


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Re: Snorting codeine? [Re: s240779]
    #14139418 - 03/17/11 08:55 PM (12 years, 10 months ago)

First past metabolism works the same as second pass metabolism.  I'm really not sure what you're trying to say.  They're both liver metabolism.  They both exactly the same thing.

I'm getting too drunk for this.  I'll talk to you in the morning.  In the mean time, google is your friend.


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Re: Snorting codeine? [Re: BothHands]
    #14139484 - 03/17/11 09:05 PM (12 years, 10 months ago)

snort drugs, swallow drugs, inject drugs, smoke drugs, ...

it's all good :awesomenod:


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OfflineHajnal
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Re: Snorting codeine? [Re: Beanhead]
    #14139543 - 03/17/11 09:16 PM (12 years, 10 months ago)

Quote:

Beanhead said:
snort drugs, swallow drugs, inject drugs, smoke drugs, ...

it's all good :awesomenod:




--------------------
Hajnal ['hɒjnɒl] - An elegant mixture of blood and circuitry; sorrow and love fill your systems, like the stars and black holes encompass the ∞.


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Re: Snorting codeine? [Re: Hajnal]
    #14139634 - 03/17/11 09:29 PM (12 years, 10 months ago)

Dude. Ewww. Snorting Pharms, only exception I would ever make considering everything I snorted is oxycontin. I guess Welliburtin is ok to snort if you are in jail as well; better then nothing. Got to love psychiatrists; even get high in jail. Man if I ever went to prison I'd probably take solitary, kill someone immediately to avoid the gangs and butt sex; and just get high. Man I'm not even sure killing prisoners gets you solitary, I guess attack a police officer instead?

Whatever. Jail ain't fun, I couldn't imagine prison. Why use pharms when you can smoke weed and do mushrooms? I don't get it man. I'd only use pharms if I had too. Cocaine is a pretty nasty drug in high doses, I recommend growing a plant or two and just chewing on a leaf. It's much better, safer, healthier then pharms and cocaine.

Unless I'm off my rocker, codeine is derived from cocaine.


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Offlines240779
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Re: Snorting codeine? [Re: iluvfungi]
    #14139653 - 03/17/11 09:32 PM (12 years, 10 months ago)

Quote:

iluvfungi said:
Unless I'm off my rocker, codeine is derived from cocaine.




Ewwww! Your ignorance disgusts me!


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OfflineBothHands
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Re: Snorting codeine? [Re: iluvfungi]
    #14139666 - 03/17/11 09:34 PM (12 years, 10 months ago)

:wow:


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Offlinelil_demented
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Re: Snorting codeine? [Re: s240779]
    #14139671 - 03/17/11 09:35 PM (12 years, 10 months ago)

Quote:

iluvfungi said:
Unless I'm off my rocker, codeine is derived from cocaine.




:brilliant:: Interesting... tell me more of this "driving" process...


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OfflineBeanhead
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Re: Snorting codeine? [Re: iluvfungi]
    #14139805 - 03/17/11 09:51 PM (12 years, 10 months ago)

Quote:

iluvfungi said:
Dude. Ewww. Snorting Pharms, only exception I would ever make considering everything I snorted is oxycontin. I guess Welliburtin is ok to snort if you are in jail as well; better then nothing. Got to love psychiatrists; even get high in jail. Man if I ever went to prison I'd probably take solitary, kill someone immediately to avoid the gangs and butt sex; and just get high. Man I'm not even sure killing prisoners gets you solitary, I guess attack a police officer instead?

Whatever. Jail ain't fun, I couldn't imagine prison. Why use pharms when you can smoke weed and do mushrooms? I don't get it man. I'd only use pharms if I had too. Cocaine is a pretty nasty drug in high doses, I recommend growing a plant or two and just chewing on a leaf. It's much better, safer, healthier then pharms and cocaine.

Unless I'm off my rocker, codeine is derived from cocaine.




:facepalm:

Take some more mushrooms


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