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Boogie1
Goldpanner


Registered: 03/08/11
Posts: 2
Loc: Vancouver
Last seen: 12 years, 10 months
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Prozac(Fluoxetine) and shrooms
#14090110 - 03/08/11 11:43 PM (12 years, 10 months ago) |
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Hello all,
I have been prescribed to Prozac today and tomorrow(Mar 9Th), will be the first day of a daily dose of 10mg. I have done shrooms 3 times, amounts averaging 3gms a night. Me and my buddy planned on doing them this coming saturday (Mar 12Th) and we're planning on doing more than usual, around 5-6gms I'm thinking. I am wondering if and how it will affect my trip, if it is a good idea to do that amount of shrooms(or any amount) and finally what physical/mental related effects in taking both of these drugs at once can do to me. Thanks.
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YOU
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irie.one
I Respect I Eternally



Registered: 03/07/11
Posts: 157
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Re: Prozac(Fluoxetine) and shrooms [Re: Boogie1]
#14090143 - 03/08/11 11:47 PM (12 years, 10 months ago) |
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I'm currently taking citalopram (Celexa), also an SSRI. I don't have any trouble tripping on it. It's difficult to quantify how the SSRI effects a trip, but generally there is a 25-33% reduction in the strength of the trip, if I had to estimate. Also, since you're just beginning your treatment, you will probably not have a reduced trip three days later. It takes almost a month for SSRIs to take full effect. There is no harm in taking both drugs at the same time.
-------------------- gettin' high to balance out the lows
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ifoundwaldo


Registered: 09/28/10
Posts: 8,389
Loc: Denver, CO
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Re: Prozac(Fluoxetine) and shrooms [Re: Boogie1]
#14090248 - 03/09/11 12:08 AM (12 years, 10 months ago) |
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irie.one's story is out of the ordinary.
SSRIs and psilocin both bind to the 5-HT2A receptor site with SSRIs having the higher affinity. So... SSRIs will pretty much negate the effects of mushrooms.
You can overcome this by taking larger doses, potentiating with piracetam, or briefly stopping your Prozac (you must start taking it again within 1-2 days).
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Boogie1
Goldpanner


Registered: 03/08/11
Posts: 2
Loc: Vancouver
Last seen: 12 years, 10 months
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Re: Prozac(Fluoxetine) and shrooms [Re: ifoundwaldo]
#14094932 - 03/09/11 08:59 PM (12 years, 10 months ago) |
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thanks for the help, i think i might do around 7-8grams. any other suggestions and answers are welcome
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YOU
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redgreenvines
irregular verb


Registered: 04/08/04
Posts: 37,539
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Re: Prozac(Fluoxetine) and shrooms [Re: Boogie1]
#14096461 - 03/10/11 06:00 AM (12 years, 10 months ago) |
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I imagine the ssri's raise your baseline.
they raise you from depressed (in the ruts/trenches of thought) mode into a slightly elevated state of mind that facilitates getting out of ruts, or seeing over the fences that separate possibilities in your mind.
regular doses of ssri's reduce the impact of psychedelics - in my opinion this is more akin to the tolerance effect of doing psychedelics the next day or 2 days later; i.e. the raised baseline becomes the norm, the mind adapts to increased resonance, and to less of a chained down modality.
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