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13.step
cynical bastard



Registered: 08/30/09
Posts: 2,210
Last seen: 9 years, 4 months
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Re: Opiates for depression [Re: bigmike7104]
#14071189 - 03/05/11 02:25 PM (12 years, 11 months ago) |
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Yeah, the placebo effect was lower than the usual rates and the SSRI response stayed the same, why was that so? Placebo response was high as it was in mild depression, severe depression doesn't respond as well as mild depression to placebo but responds the same to SSRI's. As I see it that means that the placebo works so well because it adresses the psychological aspect of depression and that is often enough. The more severe the depression gets the less of an effect that plays while the medication still mentains it's efficacy. Poke a hole trough that one...

I'm a medical shaman inhabited by demons of the 2nd realm.
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Not to be taken seriously by any means!
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bigmike7104
Stranger

Registered: 07/12/10
Posts: 1,395
Loc: USA
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Re: Opiates for depression [Re: 13.step]
#14071412 - 03/05/11 03:23 PM (12 years, 11 months ago) |
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Quote:
The more severe the depression gets the less of an effect that plays while the medication still mentains it's efficacy.
it doesn't matter if a drug is proven to be effective or not, the placebo affects around the same amount of people in both cases. so your wrong in thinking that the more effective a drug gets, the less of a role it plays in it.
if you compared the severe depressed group to normal placebo results it would show it's not effective. what your saying is against studies done by scientists that are in peer-reviewed journals. yet your the one that must be right.
and i'm curious if you could find me a study supporting the chemical imbalance theory of depression in a peer-review journal.
-------------------- Over thinking, over analyzing separates the body from the mind Withering my intuition, missing opportunities and I must Feed my will to feel my moment drawing way outside the lines
Edited by bigmike7104 (03/05/11 09:03 PM)
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d33p
Welcome to Violence

Registered: 07/12/03
Posts: 5,381
Loc: the shores of Tripoli
Last seen: 10 years, 9 months
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Re: Opiates for depression [Re: bigmike7104]
#14071607 - 03/05/11 04:11 PM (12 years, 11 months ago) |
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A week ago I was really depressed and felt like nothing could change it. I knew what I had to do but didn't care about it and I didn't think that accomplishing any of it would make me feel better anyway. Even sleeping or lying down was terrible and I felt more suicidal then I have in about 10 years.
I ended up eating a roxicet and smoking some weed one night. I felt a lot better about everything and was able to get a good sleep. When I woke up I ate 20mg of adderal which gave me the motivation to start doing what I needed to do which made me feel even better about myself. I felt fine when it wore off and that night was good. I didn't even need weed.
I haven't felt the need to do anymore roxicet or adderal since then but I now feel happy, productive, and hopeful about the future. I really feel like the roxicet and adderal helped shock me out of the depression.
I would seriously recommend against developing a drug dependency to deal with depression.
-------------------- I'm a nihilist. Lets be friends. bang bang
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13.step
cynical bastard



Registered: 08/30/09
Posts: 2,210
Last seen: 9 years, 4 months
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Re: Opiates for depression [Re: bigmike7104]
#14071790 - 03/05/11 04:48 PM (12 years, 11 months ago) |
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Coherency. It ain't just a fancy word.
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Not to be taken seriously by any means!
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