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Offlineifihadlegs
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*DELETED*
    #14041121 - 02/28/11 10:42 AM (13 years, 6 days ago)

Post deleted by ifihadlegs<p>Reason for deletion: google

Edited by ifihadlegs (08/19/11 05:54 PM)

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InvisibleTangich

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Re: New shroom user with a few questions [Re: ifihadlegs]
    #14041136 - 02/28/11 10:45 AM (13 years, 6 days ago)

The problem is in the SSRI medications you take.

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Offlineifihadlegs
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Re: New shroom user with a few questions *DELETED* [Re: Tangich]
    #14041139 - 02/28/11 10:46 AM (13 years, 5 days ago)

Post deleted by ifihadlegs

Reason for deletion: google


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Offlineshroomtastic89
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Re: New shroom user with a few questions [Re: Tangich]
    #14041140 - 02/28/11 10:46 AM (13 years, 5 days ago)

take lots of vit c with your dose and skip your SSRI medicines for the day you plan to eat them... Also make sure your stomach is close to empty...

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Invisiblesui
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Re: New shroom user with a few questions [Re: ifihadlegs]
    #14041164 - 02/28/11 10:51 AM (13 years, 5 days ago)

Quote:

ifihadlegs said:
Would you be able to elaborate on that a little bit?




well, SSRI is an acronym for selective serotonin re-uptake inhibitor

the serotonin receptor system is the system that the mushrooms also work on. Given the similar structure of psilocin to serotonin, it prevents the drug from binding properly and having an effect.

skip the SSRIs for a few days then eat the mushrooms again.


--------------------

"There is never a wrong note, bend it."
Jimi Hendrix


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InvisibleTangich

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Re: New shroom user with a few questions [Re: shroomtastic89]
    #14041167 - 02/28/11 10:52 AM (13 years, 5 days ago)

I'm not sure of the exact interactions in the brain, but SSRIs prevent psychedelics from affecting you, or at least reduce their effects significantly. Try searching about the subject, I remember reading very detailed threads about the problem.
Yes, that is good advice, take them on empty stomach, take vitC pills before, I'm just not sure if one day detoxification from zoloft would be enough.

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Offlineifihadlegs
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Re: New shroom user with a few questions *DELETED* [Re: Tangich]
    #14041188 - 02/28/11 10:58 AM (13 years, 5 days ago)

Post deleted by ifihadlegs

Reason for deletion: google


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Invisiblesui
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Re: New shroom user with a few questions [Re: ifihadlegs]
    #14041212 - 02/28/11 11:04 AM (13 years, 5 days ago)

yes. id stop using the SSRIs for a few days before using any psychedelic that works on the seretonin receptors.


--------------------

"There is never a wrong note, bend it."
Jimi Hendrix


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OfflinePsilocyentist
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Re: New shroom user with a few questions [Re: ifihadlegs]
    #14041213 - 02/28/11 11:04 AM (13 years, 5 days ago)

Quote:

ifihadlegs said:
The half-life of Zoloft in the body is 10-35 hours, so I would probably have to stop taking them for at least 2 days. I don't know if I'm comfortable doing that right now.
I'm also planning on trying LSD this spring. Do you think I'll encounter the same problem there? I've read that the two drugs are structurally similar.



Yes.


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I know, I know you probably scream and cry

That your little world won't let you go


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OfflineLanLord
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Re: New shroom user with a few questions [Re: Psilocyentist]
    #14041369 - 02/28/11 11:38 AM (13 years, 5 days ago)

The SSRI is very likely the cause, not weight.  Activity is based on the number of receptors in the brain, not the weight of the body.

HOWEVER

I'm not sure recommending someone stops taking their medicine is a good idea at all!

Apparently the SSRI was prescribed for a reason, simply stopping for a couple days so you can trip sounds like a recipe for severe depression or perhaps a manic state in the coming days.

Please reconsider your use of psychedelics at this time.


--------------------
Good judgment comes from experience, and a lotta that comes from bad judgment.

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Invisibleifoundwaldo


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Re: New shroom user with a few questions [Re: LanLord]
    #14042119 - 02/28/11 01:34 PM (13 years, 5 days ago)

Ceasing SSRIs is actually far more dangerous than that.
http://en.wikipedia.org/wiki/SSRI_discontinuation_syndrome

You can safely use piracetam and choline to potentiate the psychedelics.
Combined with missing your SSRI dose the day before you will trip...
And upping the dose by 2X or so...
You should still be able to trip.
EDIT: It is imperative that you resume your regular SSRI schedule the day of your trip though.

The problem is that the SSRIs also want to bind to the 5-HT2A receptors and have a higher affinity (than psychedelics) for these receptors.


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Edited by ifoundwaldo (02/28/11 01:35 PM)

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OfflineAzure Essence
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Re: New shroom user with a few questions [Re: ifoundwaldo]
    #14042942 - 02/28/11 03:28 PM (13 years, 5 days ago)

If you are not comfortable getting off your dangerous drugs for 2 days, you will not be comfortable taking LSD or mushrooms.

You have to give up your control and be willing to part with whatever behaviours(yes BEHAVIOURS, not STATE) you act on that make you think you need this.

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InvisibleAustrip
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Re: New shroom user with a few questions [Re: Azure Essence]
    #14043001 - 02/28/11 03:39 PM (13 years, 5 days ago)

personally I feel like if you rely on a medication to provide you happiness/keep your mood level, then psychedelics are probably not a choice for you at this point in time.

I have a few friends on depression medications that I refuse to give psychedelics to anymore for that same reason. Acid seems to make them trip but only for a few hours and never as intense as the rest of the group.
And they aren't willing to not take the meds for a day because they feel like popping there magic depression pills is the only thing that keeps them going.

Depression medication and psychedelic use is usually a sad circle to be in unfortunately.


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Invisibleifoundwaldo


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Re: New shroom user with a few questions [Re: ifihadlegs]
    #14043129 - 02/28/11 03:59 PM (13 years, 5 days ago)

Quote:

ifihadlegs said:
The half-life of Zoloft in the body is 10-35 hours, so I would probably have to stop taking them for at least 2 days. I don't know if I'm comfortable doing that right now.
I'm also planning on trying LSD this spring. Do you think I'll encounter the same problem there? I've read that the two drugs are structurally similar.




I am telling you that IME you will notice if you only stop taking them for one day (you can resume the same day that you take the psychedelics).

I'm not going to name names, but advising anyone to stop SSRIs cold turkey is stupid, careless, DANGEROUS advice.


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OfflineHarryL
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Re: New shroom user with a few questions [Re: ifoundwaldo]
    #14043477 - 02/28/11 04:57 PM (13 years, 5 days ago)

Mushrooms or LSD is not for everyone... Skip them


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OfflinepsilocybinjunkieM
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Re: New shroom user with a few questions [Re: HarryL]
    #14043682 - 02/28/11 05:28 PM (13 years, 5 days ago)

Another pillhead that wants to trip.

Stop taking the pills if you wanna trip, otherwise you will not be able too.

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OfflineAzure Essence
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Re: New shroom user with a few questions [Re: ifoundwaldo]
    #14044615 - 02/28/11 07:25 PM (13 years, 5 days ago)

Quote:

ifoundwaldo said:
Quote:

ifihadlegs said:
The half-life of Zoloft in the body is 10-35 hours, so I would probably have to stop taking them for at least 2 days. I don't know if I'm comfortable doing that right now.
I'm also planning on trying LSD this spring. Do you think I'll encounter the same problem there? I've read that the two drugs are structurally similar.




I am telling you that IME you will notice if you only stop taking them for one day (you can resume the same day that you take the psychedelics).

I'm not going to name names, but advising anyone to stop SSRIs cold turkey is stupid, careless, DANGEROUS advice.




I was really hoping it was actually a subtle suggestion that she shouldnt be using psy's until she is at a period where she doesnt need the others.

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InvisibleLand_Crab
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Re: New shroom user with a few questions [Re: ifihadlegs]
    #14044900 - 02/28/11 08:05 PM (13 years, 5 days ago)

SSRIs cause long-term changes in the brain.  Depending on how long you've been on Zoloft, it will usually take weeks if not months off the drug for your brain to return to a level where an average dose will have an average effect on you.  I was on SSRI-type medications for years and it took me at least 2-3 months off of them--tapered slowly under proper supervision--to get to a point where 2 grams did anything.  When I was on them I could trip and did trip a lot, but my starting dose was 5.5 grams.  (And conventional blanket wisdom does state that the safest thing for people on psychiatric medication to do is not to trip.)

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OfflineAzure Essence
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Re: New shroom user with a few questions [Re: Land_Crab]
    #14044977 - 02/28/11 08:18 PM (13 years, 5 days ago)

Also, all those rumors about psychedelics putting holes in your brain? Yeah, well, SSRI's REALLY actually put physical holes in your brain and kill your receptor sites.

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OfflinepsilocybinjunkieM
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Re: New shroom user with a few questions [Re: Azure Essence]
    #14045028 - 02/28/11 08:26 PM (13 years, 5 days ago)

but she "needs them"

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