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RonaldFuckingPaul
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Re: muscimol additction [Re: LawnPhenom]
#13479278 - 11/13/10 04:39 PM (13 years, 7 months ago) |
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hey can any of you guys give me a link to the DXM intervention episode?
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LawnPhenom
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Edited by LawnPhenom (11/13/10 04:44 PM)
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aNeway2sayHooray
Cresley Wusher



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Re: muscimol additction [Re: LawnPhenom]
#13479311 - 11/13/10 04:46 PM (13 years, 7 months ago) |
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Quote:
LawnPhenom said: Dehydrate, grind up lot, mix with applesauce imbibe. found tea gives me liquid shits
Mine are already dehydrated. So you dont do any fancy preaparation or drying? I know some people dry in an oven to help decarboxylation from ibotenic acid to muscimol.
I dried mine in a dehydrator with the heating element removed.But they are a few years old now. It is amanita season here though...
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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Arden
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Re: muscimol additction [Re: LawnPhenom]
#13479316 - 11/13/10 04:47 PM (13 years, 7 months ago) |
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Muscimol is actually a GABA agonist, not antagonist, hence the CNS depressive effects (a GABA antagonist would produce stimulation). In moderate, spaced doses I doubt it's addictive in the same sense as sedatives. Physiologically, you'll have receptor density changes but psychologically you won't be suffering withdrawal. Muscimol and others are used in some animal experiments and there are never psychopharmacology reports on behavior effects from "addiction".
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LawnPhenom
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that right i partially dehydrated on high 140f then baked door open at 200 till cracker dry. like 15-20 min
Edited by LawnPhenom (11/13/10 04:54 PM)
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LawnPhenom
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Re: muscimol additction [Re: Arden]
#13479333 - 11/13/10 04:53 PM (13 years, 7 months ago) |
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thanks for the correction and info
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aNeway2sayHooray
Cresley Wusher



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Re: muscimol additction [Re: Arden]
#13479338 - 11/13/10 04:54 PM (13 years, 7 months ago) |
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Quote:
Arden said: Muscimol is actually a GABA agonist, not antagonist, hence the CNS depressive effects (a GABA antagonist would produce stimulation). In moderate, spaced doses I doubt it's addictive in the same sense as sedatives. Physiologically, you'll have receptor density changes but psychologically you won't be suffering withdrawal. Muscimol and others are used in some animal experiments and there are never psychopharmacology reports on behavior effects from "addiction".
Thanks for chiming in and clearing that up... I am glad OP asked this question though, its got me reading on pharmacology and chemistry again.
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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Moo456
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Re: muscimol additction [Re: Arden]
#13479367 - 11/13/10 05:03 PM (13 years, 7 months ago) |
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One of the physical symptoms of GABA agonist withdrawal is convulsions though.
Maybe muscimol just doesn't mimic the function of GABA well enough for your body to decrease its normal GABA levels.
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aNeway2sayHooray
Cresley Wusher



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Quote:
aNeway2sayHooray said: Sorry to derail the thread.
I can see DXM addicition because of the NMDA antagonist effects.
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after more reading this statement means something completely different to me.. Wouldnt DXM help opiate addiction since it is an NMDA antagonist? I know Ive heard of taking DXM when trying to kick opiate dependence...hmm I am so confused.
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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LawnPhenom
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i know dxm and opiates get you higher than just opiates
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aNeway2sayHooray
Cresley Wusher



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Re: muscimol additction [Re: LawnPhenom]
#13479538 - 11/13/10 06:00 PM (13 years, 7 months ago) |
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And ibogaine lowers opiate tolerence
as well as being anti-addictive of course.
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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Moo456
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Theres a mixture called Morphidex (morphine with DXM) that increases the pain killing effects of the morphine.
Personally I wouldn't want the ratio to be 1:1 for recreational purposes. I would take 50-60mg of DXM with whatever dose of the opiate.
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aNeway2sayHooray
Cresley Wusher



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Re: muscimol additction [Re: Moo456]
#13479581 - 11/13/10 06:13 PM (13 years, 7 months ago) |
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Ah that reminds me I also read of Ibogaine increasing the analgesia of morphine...
hmm
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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LawnPhenom
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Re: muscimol additction [Re: Moo456]
#13479585 - 11/13/10 06:14 PM (13 years, 7 months ago) |
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i dont take opiates anymore never got addicted physically but watched many people. the shit steals your money and eats your soul you become a slave to the shit. but have done dxm and opiates to 6o mg perks and about 80 dxm i was overwhelmed like the first time i ever did a 30mg perk
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aNeway2sayHooray
Cresley Wusher



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Re: muscimol additction [Re: LawnPhenom]
#13479608 - 11/13/10 06:19 PM (13 years, 7 months ago) |
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I trying to kick a serious heroin habit.... I am on suboxone and its been working but I would really like to try ibogaine and get off the suboxone as well.Ive had some interest in it for a few years but now that I am in the throws of physical addiction it might be time to experiment...
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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LawnPhenom
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ever think of just toughing out the withdrawl old school a few days of hell you may feel like and want to die but you wont, just get it over with. heroin is a life long struggle unless you find out why you went for the drug you'll never beat it
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aNeway2sayHooray
Cresley Wusher



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Re: muscimol additction [Re: LawnPhenom]
#13479992 - 11/13/10 07:51 PM (13 years, 7 months ago) |
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I would love to just stick out the WD and be free of it and actually see why I should be off it but I am afraid I wont be able to take it and I would just go score some dope.
Ive never been through complete withdrawl,I get a day or 2 into it and cant take not being able to sleep compounded on top of immense physical pain,no appetite puking,shitting ect. ect...
wouldnt an intense ibogaine experience kinda take place of needing to experience the pain of WD to bee 100% free of it?
i
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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aNeway2sayHooray
Cresley Wusher



Registered: 07/07/05
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I need to go to that Buddhist temple in thailand... "The worlds toughest rehab"
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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aNeway2sayHooray
Cresley Wusher



Registered: 07/07/05
Posts: 7,653
Loc: Orphic Trench
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Just in the last few weeks since Ive been taking my suboxone regularly and not doing dope,Ive noticed my emotions on the shroomery have went from "apathetic" "depressed" to "happy" and "content"
suboxone or not,I feel one more step closer to being done with this shit and start living again.
-------------------- Mad_Larkin said: Death is just a thang.
MrJellineck said: Profits, prophets. That's all you jews think about. sheekle said: life is drugs... and music... and cat...
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