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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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LSD and Cocaine...
#13366413 - 10/21/10 12:29 PM (13 years, 3 months ago) |
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So tomorrow's the night! Im gettin a fair few hits of Lucy and im going halves with my mate on an 8th of decent coke! Not too sure what these to drugs are like mixed.. Has anyone ever done this?? Shall i mix them, or wait till the acid has worn off before hitting the sniff?? Oh decisions decisions...
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FUTURIST
In another land...


Registered: 12/02/09
Posts: 736
Last seen: 3 years, 12 days
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13366423 - 10/21/10 12:33 PM (13 years, 3 months ago) |
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You make me sick.... why would wreck a LSD trip.. coke is a loser drug its not mind expanding
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Re: LSD and Cocaine... [Re: FUTURIST]
#13366432 - 10/21/10 12:35 PM (13 years, 3 months ago) |
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Quote:
FUTURIST said: You make me sick.... why would wreck a LSD trip.. coke is a loser drug its not mind expanding 
Lol harsh words there...
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ifoundwaldo


Registered: 09/28/10
Posts: 8,389
Loc: Denver, CO
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Re: LSD and Cocaine... [Re: FUTURIST]
#13366433 - 10/21/10 12:36 PM (13 years, 3 months ago) |
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why would you even..............this post is dumb.
my advice would be to remove yourself from the gene pool ASAP.
--------------------
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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wtf have i done??
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AlmostAsCoolAs


Registered: 11/14/09
Posts: 7,215
Loc: California
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13366440 - 10/21/10 12:38 PM (13 years, 3 months ago) |
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Waste of coke man, save it for after or another time.
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Ego



Registered: 10/18/10
Posts: 184
Last seen: 12 years, 3 months
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coke man? come on. The cid sounds mighty fine, but coke? Who are you Tim Allen? Im just playing man... Do what you like i guess... IMO coke is a mind closer not expander. It is usually stuff like this people take psychedelics to break addictions of like coke,opiates, and alcohol.
Good luck with the lucy though.
-------------------- First time taking 4 hits of acid and all I can tell you is... "Art titties are the best!" LSD=Digital version of shrooms. DRUG HIT LIST: Alcohol Cannabis Mushrooms LSA LSD , Methamphetamine amphetamine Molly X
DXM DMT Nitrous Oxide Mescaline, Coke
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pfxtc
RUEXP?

Registered: 11/15/08
Posts: 21,166
Loc:
Last seen: 8 years, 5 months
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Re: LSD and Cocaine... [Re: Ego]
#13366465 - 10/21/10 12:43 PM (13 years, 3 months ago) |
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I think it sounds like fun
-------------------- koods said: Young male going by the name "Bassfreak" entered Worcester General complaining of a sharp pain in his buttock region after attending EDM event. Attending physician considered a possible diagnosis of acute rave anus, but upon further investigation it was determined there was nothing cute about patient's anus. Life-long trip report
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willo


Registered: 02/28/07
Posts: 628
Loc: 106
Last seen: 9 years, 4 months
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Well this isn't a good idea because coke will make you very fiendish and you'll probably end up doing too much of it ruining your trip.
Having said this I did a meth/lsd combo which was really fun, so I suppose it would be possible to do it with coke too. I personally wouldn't because as I said coke just clouds your judgment and you might end up having delusions about the trip.
Hope to deter you from doing stupid amounts of drugs and ending up not having a good time.
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ifoundwaldo


Registered: 09/28/10
Posts: 8,389
Loc: Denver, CO
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Re: LSD and Cocaine... [Re: Ego]
#13366469 - 10/21/10 12:45 PM (13 years, 3 months ago) |
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lolol. You want to mix LSD with cocaine. That's what you've done! That's a retarded idea.
Save the cocaine for some drunken night on the town. Good stuff.
Take the acid with some weed. Good stuff.
Just because you possess two drugs in the same place at the same time does not mean that they must both be immediately consumed.
--------------------
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ShroomMan420
91' Til Infinity....



Registered: 01/09/06
Posts: 1,232
Loc: Canada
Last seen: 5 years, 3 months
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13366476 - 10/21/10 12:46 PM (13 years, 3 months ago) |
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lol wtf is with all the hate on coke Cocaine is awesome. Never tried mixing it with acid, only stim I've mixed with it was mdma.
I'd do the acid and wait a bit see how you feel then try a line. My friend has done it before and said it made the visuals more intense.
If it's some good pure stuff then I bet it would go nicely.
-------------------- I am excited for my thoughts to become positive and of lifeful things instead of negative and suicidal things - Oceanshore23Forest
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Razzl3Frazzl3


Registered: 07/31/09
Posts: 4,630
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Re: LSD and Cocaine... [Re: FUTURIST]
#13366501 - 10/21/10 12:52 PM (13 years, 3 months ago) |
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Personally, do LSD one night, then the next night, take about 4-6 shots, then start sniffing.
Cocaethylene is formed in vivo when cocaine and ethyl alcohol have been ingested simultaneously.[1] Cocaethylene appears to, in most users, produce more euphoria and possess a longer duration of action than cocaine. Some studies suggest that it may be more cardiotoxic than cocaine. Cocaethylene is more potent than cocaine at binding to the dopamine transporter, however it is less potent at binding to the serotonin transporter and norepinephrine transporter.[3][4]
Doing it like this, you get to enjoy the high more, not scramble for another line every 10 minutes.
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bubblejoseph
Stranger
Registered: 10/07/10
Posts: 5
Last seen: 12 years, 2 months
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I did some coke and lsd this past weekend and I must say, I have never had a more terrible come down from any high in my life. If I were you I would just enjoy the lucy, as the coke will cause a terribly depressing come down in combination with the lucy, at least that is what happened to me.
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Well thanks for your comments but we'll see what happens!!
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wellage
Strange

Registered: 01/31/09
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Last seen: 11 years, 6 months
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13367385 - 10/21/10 04:59 PM (13 years, 3 months ago) |
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Quote:
MCSteveyC said: Well thanks for your comments but we'll see what happens!!
that's the spirit
fuck the haters
there is no reason cocaine can't be considered "mind expanding"
and I've known plenty of people who are worse off because they abused LSD
anyone who does drug A and then talks shit about drug B is a hypocrite. PERIOD.
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candyflip420
Original Gangster


Registered: 10/22/09
Posts: 4,019
Last seen: 8 years, 5 months
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Re: LSD and Cocaine... [Re: wellage]
#13367585 - 10/21/10 05:43 PM (13 years, 3 months ago) |
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Once me and a few friends took stamps the peak was takeing forever to come we smoked and everything . Since I was selling yay we decided to do a few lines . Then the peak came instant . Other than that , I started of my trip strong and stopped doing lines after that .
I dont know if you should snort the whole trip , but a few lines to start the trip would be good . Other than that save the rest for a drinking night !
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Salomon
ಠ︵ಠbalance ಠ_ಠweaver ಠ‿à²

Registered: 01/17/09
Posts: 25,128
Loc: America, FUCK YEAH
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Re: LSD and Cocaine... [Re: wellage]
#13367593 - 10/21/10 05:44 PM (13 years, 3 months ago) |
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cocaine+ psychedelics=
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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Austrip
P. Sub

Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: wellage]
#13367600 - 10/21/10 05:47 PM (13 years, 3 months ago) |
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Quote:
wellage said:
there is no reason cocaine can't be considered "mind expanding"
and I've known plenty of people who are worse off because they abused LSD
anyone who does drug A and then talks shit about drug B is a hypocrite. PERIOD.
If you were comparing something like meth to cocaine maybe, but psychedelics should never be lumped up with those droogs IMO.
Not questioning that you might have friends fucked from acid, I have 1 or 2 friends myself who are completely fried from dropping 15 hits at a time. But can you really say that you know people are worse off from acid, then crackheads who will suck dick in the street for a hit? Do people usually rob, steal, lie, cheat, rape, bash for acid? just my 2 cents 
Thats why in this case, we can talk about Drug A, and talk shit on drug B.
OP, If I was you I would snort the cocaine before you do the acid, like a few days before, or the night before. Or you can just save it for another day/night to party. I hate even thinking about cocaine and meth on acid/shrooms, it feels like poison to me and my body while i'm tripping.(even though I usually love it ANY other time)
--------------------
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FUTURIST
In another land...


Registered: 12/02/09
Posts: 736
Last seen: 3 years, 12 days
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Re: LSD and Cocaine... [Re: wellage]
#13368546 - 10/21/10 08:42 PM (13 years, 3 months ago) |
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Quote:
wellage said:
Quote:
MCSteveyC said: Well thanks for your comments but we'll see what happens!!
that's the spirit
fuck the haters
there is no reason cocaine can't be considered "mind
expanding"
:laugh 2: :lau gh2:
Edited by FUTURIST (10/21/10 08:43 PM)
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valleysofneptune
Stranger



Registered: 09/10/10
Posts: 20
Loc:
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Re: LSD and Cocaine... [Re: FUTURIST]
#13368707 - 10/21/10 09:05 PM (13 years, 3 months ago) |
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cocaine is niceeee.
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drr


Registered: 05/20/09
Posts: 8,444
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Re: LSD and Cocaine... [Re: FUTURIST]
#13368711 - 10/21/10 09:06 PM (13 years, 3 months ago) |
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Uhh...Sounds edgy as fuck! I know I wouldn't do it. I think the acid on its own would probably be more enjoyable, same for the coke. Just do it another night. Unless you insist...
Edited by drr (10/21/10 09:07 PM)
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BothHands
Dog Coffee



Registered: 10/28/09
Posts: 13,177
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Re: LSD and Cocaine... *DELETED* [Re: ShroomMan420]
#13368755 - 10/21/10 09:11 PM (13 years, 3 months ago) |
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Post deleted by BothHandsReason for deletion: Misread post.
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Everything
(~} ;-}



Registered: 06/26/10
Posts: 5,157
Last seen: 6 years, 4 months
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Re: LSD and Cocaine... [Re: BothHands]
#13368820 - 10/21/10 09:23 PM (13 years, 3 months ago) |
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Didn't hunter s thompson do a few lines on acid in fear and loathing? I mean who is to say he really did, But what the hey. Wouldnt you like to be hunter s thompson for a night? Too bad, you need more drugs...
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wissman101392
Stranger
Registered: 08/28/10
Posts: 11
Last seen: 9 years, 6 months
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i like coke and lsd but could never imaging my self taking them both at the same time i thank it would be a wast of money one will over come the other or just fuck up both
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numonkei
Back! From thedigestive tractof dave theiguana!


Registered: 04/12/06
Posts: 2,500
Loc: A Tree
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13368989 - 10/21/10 09:56 PM (13 years, 3 months ago) |
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Much of the cocaine effect will be lost under the influence of LSD. If you have any qualms with cocaine culture that may be expanded upon on LSD it may also trigger a bad introspective trip.
And disregard the drug snobs, they don't understand that it's all ok, or none of it is ok. May they not get arrested for hallucinogen possession, because their state of mind slightly expanded is the reason such a thing is possible in the first place.
~Monk
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pfxtc
RUEXP?

Registered: 11/15/08
Posts: 21,166
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Last seen: 8 years, 5 months
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Re: LSD and Cocaine... [Re: numonkei]
#13369417 - 10/21/10 11:48 PM (13 years, 3 months ago) |
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So many people here who have done psychedeics 2 or 3 times think it's ok to become drug nazi's and tell others that doing certain drugs is ok and certain drugs makes them bad. If it's not you, don't worry about it, every trip is completely up to the individual.
-------------------- koods said: Young male going by the name "Bassfreak" entered Worcester General complaining of a sharp pain in his buttock region after attending EDM event. Attending physician considered a possible diagnosis of acute rave anus, but upon further investigation it was determined there was nothing cute about patient's anus. Life-long trip report
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abltsandwich
JFK = Jelly Donut




Registered: 06/16/09
Posts: 11,537
Loc: Dildoville
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Re: LSD and Cocaine... [Re: pfxtc]
#13370269 - 10/22/10 08:27 AM (13 years, 3 months ago) |
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I wouldn't want to be fiending for more blow, or worse crashing on it, while tripping. That sounds to me like it would turn into a bad time.
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Well i've got them now!! So we'll have to see what happends!!
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Salomon
ಠ︵ಠbalance ಠ_ಠweaver ಠ‿à²

Registered: 01/17/09
Posts: 25,128
Loc: America, FUCK YEAH
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13370409 - 10/22/10 09:14 AM (13 years, 3 months ago) |
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Quote:
MCSteveyC said: Well i've got them now!! So we'll have to see what happends!!

-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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wellage
Strange

Registered: 01/31/09
Posts: 2,467
Last seen: 11 years, 6 months
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Re: LSD and Cocaine... [Re: Salomon]
#13370589 - 10/22/10 10:02 AM (13 years, 3 months ago) |
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Quote:
Austrip said: But can you really say that you know people are worse off from acid, then crackheads who will suck dick in the street for a hit? Do people usually rob, steal, lie, cheat, rape, bash for acid? just my 2 cents 
Thats why in this case, we can talk about Drug A, and talk shit on drug B.
You're generalizing here again... Do most people who do cocaine occasionally (like op) do any of that stuff?
You are just jumping to an extreme.. like the worst of the DARE retards.
Cocaine does not = dick sucking crackhead
it takes a lot more than just cocaine to turn someone into that.
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: wellage]
#13370720 - 10/22/10 10:42 AM (13 years, 3 months ago) |
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did you not read this part?
Quote:
I hate even thinking about cocaine and meth on acid/shrooms, it feels like poison to me and my body while i'm tripping.(even though I usually love it ANY other time)
I actually love cocaine, but seldom use it. I by no means think that the chemical alone does that to people, but the comparison is there to be made in my opinion.
--------------------
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Undertow2012
Registered: 10/20/10
Posts: 127
Loc: Bay Area
Last seen: 2 years, 12 days
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Re: LSD and Cocaine... [Re: Austrip]
#13371122 - 10/22/10 12:02 PM (13 years, 3 months ago) |
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In my experience cocaine creates a false sense of egotism and I think I'm a king. It feels amazing but I don't like to delude myself with that way of thinking.
LSD makes me shed my ego. It makes me shed myself and I can explore things without my petty self getting in the way.
In my experiences with the two drugs (never done them at the same time) this would make for a bad trip, I think the LSD would make me realize how much the coke is just "getting in the way".
But that's my opinion...
-------------------- Just looking at fungi.
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Its fuckin mad but nice!!! i like it!!
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FUTURIST
In another land...


Registered: 12/02/09
Posts: 736
Last seen: 3 years, 12 days
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Quote:
Undertow2012 said: In my experience cocaine creates a false sense of egotism and I think I'm a king. It feels amazing but I don't like to delude myself with that way of thinking.
LSD makes me shed my ego. It makes me shed myself and I can explore things without my petty self getting in the way.
In my experiences with the two drugs (never done them at the same time) this would make for a bad trip, I think the LSD would make me realize how much the coke is just "getting in the way".
But that's my opinion...
A+ well said.
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blazenn
rawdog the whale.


Registered: 05/13/09
Posts: 4,584
Loc:
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Re: LSD and Cocaine... [Re: FUTURIST]
#13371590 - 10/22/10 01:59 PM (13 years, 3 months ago) |
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Quote:
FUTURIST said: You make me sick.... why would wreck a LSD trip.. coke is a loser drug its not mind expanding 
LOL at all the ASSHURT fucking hippies getting pissed about OP
just because you think you're learning "secrets to the universe" on your little mushroom trips doesn't mean everybody else that takes these drugs has to search for the same meaning as you.
there is absolutely nothing wrong w/ doing some lines on lucy, it will make the lucy seem alot less prominent and it can be pretty tricky making sure you hit the line w/ a straw when you're trippin balls.
don't listen to these dirty stuck up assholes, enjoy your drugs how you want you dont need some skizo ass hippies to tell you how inferior you are cuz you do coke. ive heard that shit too much
o and this should be a lesson not to talk about anything except "soul searching enlightnement" in psychedelic experience. nothing but a bunch of self righteous hippies that think if you take psyches you HAVE to be crazy enough to think the drugs have something to "teach" you. lol what a load of fucking bullshit
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ifoundwaldo


Registered: 09/28/10
Posts: 8,389
Loc: Denver, CO
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Re: LSD and Cocaine... [Re: blazenn]
#13371614 - 10/22/10 02:04 PM (13 years, 3 months ago) |
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Completely moot point now, but...
You'll notice that most of us have nothing wrong with LSD use or cocaine use individually. It's just silly to combine them. You're combining an ego killer with an ego strengthener.
Also, it's not like you're doing the cocaine for energy: the LSD gives you plenty of energy. You're doing the cocaine just because it's there, which seems a little juvenile.
As I said, it's all a moot point now.
--------------------
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blazenn
rawdog the whale.


Registered: 05/13/09
Posts: 4,584
Loc:
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no actually i would do a line on lucy because i love to snort a line. i love the taste, the feeling of snorting it, the drip, the way it makes your nostrils and throat numb. tbh i love all those things more than the actual high which is probly why i've never been hooked on the stuff, cause there's MUCH better highs out there.
like with all things, don't knock it till you try it. snorting a line any time is grrrreat. when you're already flying high on lucy taking a little bump feels really niceeeee.
fuck hippies
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FUTURIST
In another land...


Registered: 12/02/09
Posts: 736
Last seen: 3 years, 12 days
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Re: LSD and Cocaine... [Re: blazenn]
#13371751 - 10/22/10 02:39 PM (13 years, 3 months ago) |
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Your as dumb and hateful as gg allin.... junkie!!
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wellage
Strange

Registered: 01/31/09
Posts: 2,467
Last seen: 11 years, 6 months
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Re: LSD and Cocaine... [Re: FUTURIST]
#13371784 - 10/22/10 02:47 PM (13 years, 3 months ago) |
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I'd say people on LSD suffer from delusions of grandeur even MORE than those sniffing coke..
Who has ever done coke and then suddenly realize "wtf man, I'm JESUS!!"
And it's silly to assume that an "ego strengthener" (if cocaine can even be classified as this) can't teach about ONESELF just as much as an "ego killer" (again, not always so).
The idea is that there are different states that can be accessed, and none of them should be treated with attachment as lots of you have proved you do.
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wellage
Strange

Registered: 01/31/09
Posts: 2,467
Last seen: 11 years, 6 months
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Re: LSD and Cocaine... [Re: Austrip]
#13371786 - 10/22/10 02:48 PM (13 years, 3 months ago) |
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Quote:
Austrip said: did you not read this part?
Quote:
I hate even thinking about cocaine and meth on acid/shrooms, it feels like poison to me and my body while i'm tripping.(even though I usually love it ANY other time)
I actually love cocaine, but seldom use it. I by no means think that the chemical alone does that to people, but the comparison is there to be made in my opinion.
The you using it part is what makes you a hypocrite for employing DARE tactics to comparisons.
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Bassfreak
ManBearPig



Registered: 08/24/10
Posts: 18,014
Last seen: 8 years, 5 months
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Re: LSD and Cocaine... [Re: wellage]
#13371945 - 10/22/10 03:18 PM (13 years, 3 months ago) |
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ive done coke and acid mixed together plenty of times...for me i personally like it...ur tripping but at the same time u can still talk to people and ur face is completely numb and that fucks with you so much when ur trippin lol
-------------------- Tom Brady is a God Free Tom Brady
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Re: LSD and Cocaine... [Re: Bassfreak]
#13372058 - 10/22/10 03:41 PM (13 years, 3 months ago) |
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im fuckin on it now and its wicked!!!!
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spock
journeyman
Registered: 08/26/03
Posts: 1,165
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Quote:
FUTURIST said: You make me sick.... why would wreck a LSD trip.. coke is a loser drug its not mind expanding 
Quote:
ifoundwaldo said: why would you even..............this post is dumb.
my advice would be to remove yourself from the gene pool ASAP.
Narrow minded drug snobs.
Spock
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Re: LSD and Cocaine... [Re: spock]
#13372206 - 10/22/10 04:14 PM (13 years, 3 months ago) |
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tossers!
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Subconscious
Stranger



Registered: 09/19/08
Posts: 2,486
Last seen: 5 years, 2 months
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13372236 - 10/22/10 04:20 PM (13 years, 3 months ago) |
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I have no problem with cocaine, but this seems like a bad combo.
LSD can be very stimulating at high doses, and can increase your heart rate. It's not dangerous, but it can fuck with your mind. I've had trips on LSD alone where it felt like my heart was beating out of my chest... and it put me in a bad space mentally. Adding cocaine to that just sounds like a bad idea, and potentially could be dangerous.
Dose lightly and be safe dude
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SuicideCommando
Seeker


Registered: 09/21/08
Posts: 290
Last seen: 2 years, 4 months
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LSD can expand the mind and open you to new ways to think. Coke does nothing but destroy.
-------------------- I have never killed a man, but I have read many obituaries with great pleasure.
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Dr. Siekadellyk
Look at the corruption!




Registered: 11/19/08
Posts: 2,580
Loc: Floating amidst nothing
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13372264 - 10/22/10 04:28 PM (13 years, 3 months ago) |
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I have nothing to include in this thread, I just want to read the ridiculous replies 
Good vibes to you man...
-------------------- -My ISO list- -My trade list-
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ifoundwaldo


Registered: 09/28/10
Posts: 8,389
Loc: Denver, CO
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--------------------
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Bassfreak
ManBearPig



Registered: 08/24/10
Posts: 18,014
Last seen: 8 years, 5 months
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i think its funny that most of the people in this thread clearly havent mixed the 2 drugs, yet they think they know exactly what the outcome would be...all of u stfu cuz u have no idea...ive done coke and acid tons of times and its a fun mix...a coke high and a lsd high mixed together, really nothing more complicated than that
-------------------- Tom Brady is a God Free Tom Brady
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420happyhippy
Swamp Dunkey



Registered: 06/23/10
Posts: 818
Loc: The Herion Capital of Ame...
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Lol, I'd go all out.
Take the Acid for the crazy electric body high. Do some shroomys for the visual aspect Drop some Molly to take of the edge Snort hella coke to amp shit up Then eat some morphine to smoooooooth it out.
after that, get a blanket, and a bowl, and enjoy the night sky with a good friend!
lol, Nirtous can come too!
-------------------- "I AM, WAS, AND ALWAYS WILL BE."
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SuicideCommando
Seeker


Registered: 09/21/08
Posts: 290
Last seen: 2 years, 4 months
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Or, sell the acid to get money for more coke, which you will inevitably need.
-------------------- I have never killed a man, but I have read many obituaries with great pleasure.
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Dr. Siekadellyk
Look at the corruption!




Registered: 11/19/08
Posts: 2,580
Loc: Floating amidst nothing
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-------------------- -My ISO list- -My trade list-
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420happyhippy
Swamp Dunkey



Registered: 06/23/10
Posts: 818
Loc: The Herion Capital of Ame...
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dude, mother fuck the "all natural hippy" bullshit. If your a pleasure seeker with an open mind, you can do whatever the fuck you want. And with moderation, not only is it fun, but its safe.
to the hippy with shrooms the young punk with robotussin the homeless dude with herion or the normal joe, with his joint and his beer.
we are all the same. just people trying to get high and feel good.
i dont care if you do drugs for spirtual reasons, or having fun with friends, or just a crack head in the alley way. When you boil it down it is all the same.
DO SHIT, GET REACTION.
be proud of your adventures and fuck anyone who judges.
HH
-------------------- "I AM, WAS, AND ALWAYS WILL BE."
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Salomon
ಠ︵ಠbalance ಠ_ಠweaver ಠ‿à²

Registered: 01/17/09
Posts: 25,128
Loc: America, FUCK YEAH
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Quote:
420happyhippy said:
we are all the same. just people trying to get high and feel good.
people gonna do what 
theres no reason to hate on what people are doin' cause you're doin' thangs that other people are gonna hate on, you know that you are.
ya might like to do coke and acid, or ya might like to strangle yourself when you jerk it, either way, you're doin' the thangs ya love.
it's all about the love, baby
ooooooooooooooohhhhhhh yeaaaaaaaaaa
-------------------- EVERYTHING EVENTUALLY BECOMES A DESERT
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420happyhippy
Swamp Dunkey



Registered: 06/23/10
Posts: 818
Loc: The Herion Capital of Ame...
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Re: LSD and Cocaine... [Re: Salomon]
#13372720 - 10/22/10 05:56 PM (13 years, 3 months ago) |
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Lol, I strangle myself while I masterbate everyday before work!
-------------------- "I AM, WAS, AND ALWAYS WILL BE."
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drr


Registered: 05/20/09
Posts: 8,444
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Quote:
Subconscious said: I have no problem with cocaine, but this seems like a bad combo.
LSD can be very stimulating at high doses, and can increase your heart rate. It's not dangerous, but it can fuck with your mind. I've had trips on LSD alone where it felt like my heart was beating out of my chest... and it put me in a bad space mentally. Adding cocaine to that just sounds like a bad idea, and potentially could be dangerous.
Dose lightly and be safe dude
This is what would worry me too
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Bruce6000
DaGoodDaBombDaBuddha


Registered: 07/04/08
Posts: 348
Last seen: 2 years, 3 months
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Re: LSD and Cocaine... [Re: drr]
#13372888 - 10/22/10 06:31 PM (13 years, 3 months ago) |
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What's the big deal, you'll just be a highly energetic, confident acidhead.
-------------------- Nothing can enslave you other than your unguided attention
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Wark
Chemist/Pharma-freak



Registered: 10/17/10
Posts: 17
Loc: The doldrums
Last seen: 12 years, 8 months
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Re: LSD and Cocaine... [Re: FUTURIST]
#13372894 - 10/22/10 06:32 PM (13 years, 3 months ago) |
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Quote:
FUTURIST said: You make me sick.... why would wreck a LSD trip.. coke is a loser drug its not mind expanding 
^ Twat ^
I'd say save the llello for another time; crashing on coke while coming down from acid would be a terrible situation. Also, that would just be wayyyyy too much stimulation. And dont let little people tell you what drugs are "cool" and "not cool."
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: Wark]
#13373463 - 10/22/10 08:23 PM (13 years, 3 months ago) |
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Quote:
wellage said:
Quote:
Austrip said: did you not read this part?
Quote:
I hate even thinking about cocaine and meth on acid/shrooms, it feels like poison to me and my body while i'm tripping.(even though I usually love it ANY other time)
I actually love cocaine, but seldom use it. I by no means think that the chemical alone does that to people, but the comparison is there to be made in my opinion.
The you using it part is what makes you a hypocrite for employing DARE tactics to comparisons.
Wow what an asshole. You have no idea who I am, and what my experience with cocaine so please don't assume you have any clue.
I like cocaine a lot, I just don't use it much anymore, and I wouldn't mix these 2 drugs. If you read the first page of this thread I actually told him to snort the coke first or afterwards, I never said anything about not doing it or that its a shit drug.
Peace.
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Mr.Al
Alphabet soup



Registered: 05/27/07
Posts: 5,388
Loc: N.S.A. D.C.
Last seen: 30 days, 18 hours
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13373507 - 10/22/10 08:35 PM (13 years, 3 months ago) |
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Quote:
MCSteveyC said: So tomorrow's the night! Im gettin a fair few hits of Lucy and im going halves with my mate on an 8th of decent coke! Not too sure what these to drugs are like mixed.. Has anyone ever done this?? Shall i mix them, or wait till the acid has worn off before hitting the sniff?? Oh decisions decisions...
L.S.D. could send your blood pressure up significantly. Cocaine definitely would increase your heart rate.
I don't recommend combining these drugs as that may have serious adverse reactions for the heart.
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Bassfreak
ManBearPig



Registered: 08/24/10
Posts: 18,014
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Re: LSD and Cocaine... [Re: Mr.Al] 1
#13373554 - 10/22/10 08:45 PM (13 years, 3 months ago) |
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Quote:
Mr.Al said:
Quote:
MCSteveyC said: So tomorrow's the night! Im gettin a fair few hits of Lucy and im going halves with my mate on an 8th of decent coke! Not too sure what these to drugs are like mixed.. Has anyone ever done this?? Shall i mix them, or wait till the acid has worn off before hitting the sniff?? Oh decisions decisions...
L.S.D. could send your blood pressure up significantly. Cocaine definitely would increase your heart rate.
I don't recommend combining these drugs as that may have serious adverse reactions for the heart.
so whats your opinion on a candyflip? ecstasy and coke are very similar drugs
hinestly its better for you to mix various uppers than mixing uppers and downers
honestly u guys are all just being paranoid...ur not gonna OD on coke unless u do a bunch...im a novice coke user (ive used it a handful of times, usually in concert/rave/party situations) and ive railed a couple grams to my dome on nights before while on other drugs which obviously includes acid (and xtc and K)
idk what u guys are thinking...mixing drugs is great...not exactly responsible but u just gotta know ur limits...doin a speedball is way more dangerous than coke and lsd, but plenty of people speedball
-------------------- Tom Brady is a God Free Tom Brady
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Bruce6000
DaGoodDaBombDaBuddha


Registered: 07/04/08
Posts: 348
Last seen: 2 years, 3 months
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Re: LSD and Cocaine... [Re: Bassfreak]
#13373948 - 10/22/10 10:17 PM (13 years, 3 months ago) |
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both LSD and cocaine affect serotonin. Cocaine affects a few more neurotransmitters, dopamine is one, I forget the other.
So wouldn't that make them both uppers?
-------------------- Nothing can enslave you other than your unguided attention
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: Bruce6000]
#13373987 - 10/22/10 10:28 PM (13 years, 3 months ago) |
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Quote:
The most extensively studied effect of cocaine on the central nervous system is the blockade of the dopamine transporter protein. Dopamine transmitter released during neural signaling is normally recycled via the transporter; i.e., the transporter binds the transmitter and pumps it out of the synaptic cleft back into the presynaptic neuron, where it is taken up into storage vesicles. Cocaine binds tightly at the dopamine transporter forming a complex that blocks the transporter's function. The dopamine transporter can no longer perform its reuptake function, and thus dopamine accumulates in the synaptic cleft. This results in an enhanced and prolonged postsynaptic effect of dopaminergic signaling at dopamine receptors on the receiving neuron.
Quote:
MDMA acts as a releasing agent of serotonin, norepinephrine, and dopamine.[42] It enters neurons via carriage by the monoamine transporters.[42] Once inside, MDMA inhibits the vesicular monoamine transporter, which results in increased concentrations of serotonin, norepinephrine, and dopamine into the cytoplasm,[43] and induces their release by reversing their respective transporters through a process known as phosphorylation.[44] It also acts as a weak 5-HT1 and 5-HT2 receptor agonist, and its more efficacious metabolite MDA likely augments this action.
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
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Re: LSD and Cocaine... [Re: Austrip]
#13374206 - 10/22/10 11:38 PM (13 years, 3 months ago) |
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Quote:
Mr.Al said:
Quote:
MCSteveyC said: So tomorrow's the night! Im gettin a fair few hits of Lucy and im going halves with my mate on an 8th of decent coke! Not too sure what these to drugs are like mixed.. Has anyone ever done this?? Shall i mix them, or wait till the acid has worn off before hitting the sniff?? Oh decisions decisions...
L.S.D. could send your blood pressure up significantly. Cocaine definitely would increase your heart rate.
I don't recommend combining these drugs as that may have serious adverse reactions for the heart.
Quote:
SuicideCommando said: LSD can expand the mind and open you to new ways to think. Coke does nothing but destroy.
Quote:
Austrip said: Quote:
The most extensively studied effect of cocaine on the central nervous system is the blockade of the dopamine transporter protein. Dopamine transmitter released during neural signaling is normally recycled via the transporter; i.e., the transporter binds the transmitter and pumps it out of the synaptic cleft back into the presynaptic neuron, where it is taken up into storage vesicles. Cocaine binds tightly at the dopamine transporter forming a complex that blocks the transporter's function. The dopamine transporter can no longer perform its reuptake function, and thus dopamine accumulates in the synaptic cleft. This results in an enhanced and prolonged postsynaptic effect of dopaminergic signaling at dopamine receptors on the receiving neuron.
Quote:
MDMA acts as a releasing agent of serotonin, norepinephrine, and dopamine.[42] It enters neurons via carriage by the monoamine transporters.[42] Once inside, MDMA inhibits the vesicular monoamine transporter, which results in increased concentrations of serotonin, norepinephrine, and dopamine into the cytoplasm,[43] and induces their release by reversing their respective transporters through a process known as phosphorylation.[44] It also acts as a weak 5-HT1 and 5-HT2 receptor agonist, and its more efficacious metabolite MDA likely augments this action.
blah blah
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stuntmanmike



Registered: 09/16/10
Posts: 836
Last seen: 11 years, 10 months
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13376877 - 10/23/10 04:18 PM (13 years, 3 months ago) |
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I don't think LSD and coke are good companions, the last thing you need with hallucinations is confidence.
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Bassfreak
ManBearPig



Registered: 08/24/10
Posts: 18,014
Last seen: 8 years, 5 months
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Quote:
stuntmanmike said: I don't think LSD and coke are good companions, the last thing you need with hallucinations is confidence.
yeah...but like you and more than half the people posting in this thread...u have no idea what its like to do em both...leave it to the people with actual experience with this mixture
the only people saying this is a bad combo are people who havent done it and its annoying as fuck cuz all it is, is speculation...in reality none of you have any idea at all...its a great and fun mix
-------------------- Tom Brady is a God Free Tom Brady
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Re: LSD and Cocaine... [Re: Bassfreak]
#13386964 - 10/25/10 08:05 PM (13 years, 3 months ago) |
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Well trip report.. I started off with taking a good few trips, it kind of started off mild, i was just led in bed for the first hour watchin telly, in time things just got worse and my room went crazy everything was moving erratically. At that point i thought, "i don't need anymore" i was really enjoying it. I tripped out for about 2 hours then i decided after reading these comments on this thread i would try a line. So i did. I loved it, it sorted my head out a bit but i was still tripping my tits off, so i carried on put my headphones on and i enjoyed every min of it! I finished off my coke about 6am, took an E, and done the rest of the trips. My Mrs came round and I sat up all saturday day talkin bollocks to her, shagging, and ended up gettin a takeaway. The trip gently descended i got sleepy and went to sleep! It was brilliant! Can't wait to do it again! Nowt wrong wi doin a few lines wi acid! Its class!
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387014 - 10/25/10 08:17 PM (13 years, 3 months ago) |
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Wait so you ate all of that acid? or am I reading this wrong??
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Re: LSD and Cocaine... [Re: Austrip]
#13387038 - 10/25/10 08:22 PM (13 years, 3 months ago) |
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Yeah i ate the lot....i was messy!
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387060 - 10/25/10 08:25 PM (13 years, 3 months ago) |
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whoa that's massive dude! wasn't there like 50 hits there? That's like 2 or 3 years worth of cid for me.
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Re: LSD and Cocaine... [Re: Austrip]
#13387075 - 10/25/10 08:28 PM (13 years, 3 months ago) |
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There was 40.... i started off by taking 16 thats when my brain melted, but when i took some coke it straightened my head so i took another 12 and at the end another 12... i was trppin till sunday
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TripJunkie
Stranger

Registered: 05/14/07
Posts: 174
Loc: Southern California
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387156 - 10/25/10 08:41 PM (13 years, 3 months ago) |
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my friend said when he was having a bad trip that cocaine helped him
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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Re: LSD and Cocaine... [Re: TripJunkie] 1
#13387278 - 10/25/10 09:01 PM (13 years, 3 months ago) |
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Everyone who has said LSD and cocaine is a bad idea is completely wrong! I fuckin loved every min of it!
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cryptix420
Psilocybinatic



Registered: 03/17/10
Posts: 210
Loc:
Last seen: 11 years, 7 days
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387303 - 10/25/10 09:06 PM (13 years, 3 months ago) |
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i just feel that cocaine is a bad idea
i feel like i already know how it's going to feel without having ever done it. i don't feel very pulled towards things that feel like dead ends, know what i mean jellybeans
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
Loc:
Last seen: 13 years, 20 days
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if u aint ever done it you can't judge it!!!!
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drr


Registered: 05/20/09
Posts: 8,444
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387527 - 10/25/10 09:48 PM (13 years, 3 months ago) |
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I've done it. It is a bad idea. Stick with your instincts. That drug has never done any real good for anybody.
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cryptix420
Psilocybinatic



Registered: 03/17/10
Posts: 210
Loc:
Last seen: 11 years, 7 days
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387762 - 10/25/10 10:41 PM (13 years, 3 months ago) |
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Ey man I'm not judging anyone. Just for my own reasons...you know, loving drugs/getting fucked up/having an addictive personality...
coke doesn't seem like a crutch i need to give myself. fuckin' with dopamine scares me...those systems can't reset like serotonin
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MetalMachineMusic
Stranger


Registered: 10/03/10
Posts: 162
Loc: Darlington
Last seen: 12 years, 4 months
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I can't believe you gobbled 16 hits off acid in a oner, that's offit.
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WordsWorth
More trees then Christmas

Registered: 10/31/07
Posts: 97
Loc: Compton
Last seen: 11 years, 8 months
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I once snorted a fat .2 line of ICE and walked home to find my room mate sitting there with 3 hits of White-on-White for me..
Never in my life have i been that far. It was a ride
-------------------- Freak the establishment
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7yler

Registered: 10/24/10
Posts: 140
Last seen: 9 years, 20 days
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liquor + cocaine + ADHD = temporarily insane..
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GreenMachine
The Magician



Registered: 03/26/09
Posts: 1,298
Loc: A peninsula
Last seen: 10 years, 10 months
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Re: LSD and Cocaine... [Re: 7yler]
#13390182 - 10/26/10 12:47 PM (13 years, 3 months ago) |
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-------------------- Look behind you, do you see it?
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eyes in the sky

Registered: 03/18/10
Posts: 33
Loc: England
Last seen: 12 years, 2 months
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Quote:
GreenMachine said: Acid+Cocaine
=
What. The. Hell? I don't even know what to think of this...
-------------------- Control Is An Illusion, Order A Comforting Lie, From Chaos, Through Chaos, Into Chaos We Fly
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blazenn
rawdog the whale.


Registered: 05/13/09
Posts: 4,584
Loc:
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Quote:
eyes in the sky said:
Quote:
GreenMachine said: Acid+Cocaine
=
What. The. Hell? I don't even know what to think of this...
it isn't to inspire thoughts, it's just fucking hilarious
i fucking lolllllllllllllllllld
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AZrooj
AZ/WA



Registered: 09/02/05
Posts: 788
Loc: USA Washington
Last seen: 8 years, 5 months
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Re: LSD and Cocaine... [Re: blazenn]
#13390534 - 10/26/10 02:02 PM (13 years, 3 months ago) |
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Yeah i would have to say this is a horrible combo myself. But then again i think coke is horrible by itself also.
-------------------- Power booster, I'm talking to god and more.
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Bassfreak
ManBearPig



Registered: 08/24/10
Posts: 18,014
Last seen: 8 years, 5 months
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Re: LSD and Cocaine... [Re: AZrooj]
#13390954 - 10/26/10 03:45 PM (13 years, 3 months ago) |
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Quote:
AZrooj said: Yeah i would have to say this is a horrible combo myself. But then again i think coke is horrible by itself also. 
yeah but u havent done it...so u really dont know
lol everyone in this thread saying its a bad combo are by people who have never mixed the 2...shut the fuck up if u havent ever done it cuz u dont know...your input is irrelevant
but that randy savage video was hilarious...WTF? like hes def on sumthing, way out there
-------------------- Tom Brady is a God Free Tom Brady
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AZrooj
AZ/WA



Registered: 09/02/05
Posts: 788
Loc: USA Washington
Last seen: 8 years, 5 months
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Re: LSD and Cocaine... [Re: Bassfreak]
#13391737 - 10/26/10 06:50 PM (13 years, 3 months ago) |
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Your right I haven't done the two at the same time because coke sucks ass by itself, so why mix it LSD?
-------------------- Power booster, I'm talking to god and more.
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: Bassfreak]
#13392120 - 10/26/10 08:00 PM (13 years, 3 months ago) |
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Quote:
Bassfreak said:
lol everyone in this thread saying its a bad combo are by people who have never mixed the 2...shut the fuck up if u havent ever done it cuz u dont know...your input is irrelevant
Who are you to say who's input is relevant? its a public forum.
Back on topic... I actually don't agree with this combo because these 2 substances specifically don't seem to mix together well on a chemical level. Granted I have never tried it personally, and I have good reason not to with this information.
Am I the only one noticing this...
Quote:
The most extensively studied effect of cocaine on the central nervous system is the blockade of the dopamine transporter protein....
...Cocaine binds tightly at the dopamine transporter forming a complex that blocks the transporter's function. The dopamine transporter can no longer perform its reuptake function, and thus dopamine accumulates in the synaptic cleft. This results in an enhanced and prolonged postsynaptic effect of dopaminergic signaling at dopamine receptors on the receiving neuron.
Now if you read this instead of bypassing straight past the facts, it says that cocaine forms a block at the dopamine transporters, that blocks function.
LSD on the other hand, is known and thought to effect several of the 5-HT receptors, and in some causes a flooding of serotonin, while it blocks others.
When I read this...
Quote:
MCSteveyC said: There was 40.... i started off by taking 16 thats when my brain melted, but when i took some coke it straightened my head so i took another 12 and at the end another 12... i was trppin till sunday
I can only seem to keep coming back to these facts.
I don't know what the OP's usual dose of cid is, but 16 hits of good blot would be enough to melt any of my friends into a puddle of psychedelic goo. Let alone all 40.
I would almost be willing to say that the coke brought you back down, which certainly seems to be what happened. due to how it effects brain chemistry (as stated above) I think the coke actually blocked the release of serotonin when you actually wanted to release more (I would on 16 hits that's for sure)
With all that said, it's the OP's droogs, do what you want with them! Just all these people bitching should learn to relax. Theres 2 sides to any argument, just because someone doesn't agree doesn't make their post any less relevant then any of yours.
Peace.
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BothHands
Dog Coffee



Registered: 10/28/09
Posts: 13,177
Loc:
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Re: LSD and Cocaine... [Re: Austrip] 1
#13392188 - 10/26/10 08:14 PM (13 years, 3 months ago) |
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Wow, you couldn't be more wrong.
Yes, cocaine blocks the dopamine, norepinephrine, and serotonin transporter proteins, but it doesn't have any binding affinity to the 5-HT2A receptor. This is the primary receptor involved in the action of psychedelics. Cocaine should have no affect on psychedelics if used after the dose.
Now if you use cocaine on a daily basis, that's a completely different situation. Cocaine increases the level of serotonin in the synapses. Serotonin CAN bind to the 5-HT2A receptors. By increasing your level of serotonin for an extended period of time, you can cause the 5-HT2A receptors (as well as all the other serotonin receptors) to develop a tolerance.
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drr


Registered: 05/20/09
Posts: 8,444
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Quote:
GreenMachine said: Acid+Cocaine
=
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: BothHands]
#13392267 - 10/26/10 08:30 PM (13 years, 3 months ago) |
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Quote:
BothHands said: Wow, you couldn't be more wrong.
Yes, cocaine blocks the dopamine, norepinephrine, and serotonin transporter proteins, but it doesn't have any binding affinity to the 5-HT2A receptor. This is the primary receptor involved in the action of psychedelics. Cocaine should have no affect on psychedelics if used after the dose.
Now if you use cocaine on a daily basis, that's a completely different situation. Cocaine increases the level of serotonin in the synapses. Serotonin CAN bind to the 5-HT2A receptors. By increasing your level of serotonin for an extended period of time, you can cause the 5-HT2A receptors (as well as all the other serotonin receptors) to develop a tolerance.
Couldnt be more wrong? wow thats a bit rude, pretty sure I could if I tried 
Wasn't trying to be 100% correct, I was just trying to stimulate some more productive discussion on the matter. And adding my 2 cents
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: BothHands]
#13392323 - 10/26/10 08:43 PM (13 years, 3 months ago) |
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Quote:
BothHands said: but it doesn't have any binding affinity to the 5-HT2A receptor. This is the primary receptor involved in the action of psychedelics.
What about the 5-HT1A, 5-HT2C, 5-HT5A, and 5-HT6 receptors?
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BothHands
Dog Coffee



Registered: 10/28/09
Posts: 13,177
Loc:
Last seen: 4 years, 10 months
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Re: LSD and Cocaine... [Re: Austrip]
#13392347 - 10/26/10 08:49 PM (13 years, 3 months ago) |
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I'm quite positive the answer is no. But even if it does, LSD has a much higher binding affinity. It'll just knock the cocaine right off the receptors. It makes no difference.
The only way for cocaine to interfere with LSD is if you use it all day ever day for weeks before your dose. It has SRI activity, and because of this it can increase your tolerance in the same way that a daily regimen of SSRI antidepressants can. But only if it's used all day every day. (cocaine has a short half life, while antidepressants have a half life well over 24 hours)
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: BothHands]
#13392388 - 10/26/10 08:58 PM (13 years, 3 months ago) |
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Quote:
BothHands said: I'm quite positive the answer is no. But even if it does, LSD has a much higher binding affinity. It'll just knock the cocaine right off the receptors. It makes no difference.
The only way for cocaine to interfere with LSD is if you use it all day ever day for weeks before your dose. It has SRI activity, and because of this it can increase your tolerance in the same way that a daily regimen of SSRI antidepressants can.
Nice summary 
This still has me questioning whether or not there aren't many more interactions going on with this combo that we are still yet to discover...
Quote:
In addition to the mechanism shown on the above chart, cocaine has been demonstrated to bind as to directly stabilize the DAT transporter on the open outward-facing conformation whereas other stimulants (namely phenethylamines) stabilize the closed conformation. Further, cocaine binds in such a way as to inhibit a hydrogen bond innate to DAT that otherwise still forms when amphetamine and similar molecules are bound. Cocaine's binding properties are such that it attaches so this hydrogen bond will not form and is blocked from formation due to the tightly locked orientation of the cocaine molecule. Research studies have suggested that the affinity for the transporter is not what is involved in habituation of the substance so much as the conformation and binding properties to where & how on the transporter the molecule binds
and here...
Quote:
It also functions on the binding sites to the dopamine & serotonin sodium dependent transport area as targets as separate mechanisms from its reuptake of those transporters
anything you can add on that?
Cheers.
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BothHands
Dog Coffee



Registered: 10/28/09
Posts: 13,177
Loc:
Last seen: 4 years, 10 months
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Re: LSD and Cocaine... [Re: Austrip]
#13392419 - 10/26/10 09:04 PM (13 years, 3 months ago) |
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I really don't get what you're asking.
The red says it inhibits the DOPAMINE transport protein. Then the bolded section just explains the mechanism. What does that have to do with the SEROTONIN 2A receptor?
As for this:
Quote:
It also functions on the binding sites to the dopamine & serotonin sodium dependent transport area as targets as separate mechanisms from its reuptake of those transporters
It binds to the serotonin transport protein. That's a protein that takes serotonin out of the synapse. But the serotonin transport protein is completely different and separate to a serotonin RECEPTOR. Binding to a transport protein has no effect on the receptors. It just increases serotonin in the synapse. But LSD binds with a higher affinity than serotonin, so the serotonin wouldn't get in the way.
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: BothHands]
#13392459 - 10/26/10 09:13 PM (13 years, 3 months ago) |
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I guess in the red I was pointing out that Cocaine has traits in how it affects the DAT, which otherwise are not so when bound with amphetamines or similar.
Could just be how I'm reading it.
Quote:
Binding to a transport protein has no effect on the receptors. It just increases serotonin in the synapse. But LSD binds with a higher affinity than serotonin, so the serotonin wouldn't get in the way.
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BothHands
Dog Coffee



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Re: LSD and Cocaine... [Re: Austrip]
#13392547 - 10/26/10 09:31 PM (13 years, 3 months ago) |
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Austrip said: I guess in the red I was pointing out that Cocaine has traits in how it affects the DAT, which otherwise are not so when bound with amphetamines or similar.
The DAT is the dopamine transport protein, and has absolutely no bearing on how well psychedelics work. In fact, at recreational doses, LSD has no noticeable interaction with ANY part of the dopamine system at all.
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PsilocybinMike
T.F.Y.Q.A


Registered: 02/18/08
Posts: 2,602
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AlmostAsCoolAs said: Waste of coke man, save it for after or another time.
Seriously. I am not a huge fan of coke and have only done it a dozen or so times give or take and I once tried this combo and swore I never would again. I did the coke first and felt fucking awesome then I decided to eat 1 hit of some pretty strong alex grey doses and within 2 hours or so of eating that I felt awful. I had that "I can't fucking wait for this trip to end" feeling but at the same time I still felt like doing more coke, cause that's what coke does.
Anyway as I continue to do more coke, no matter how much I do, I can still not shake that feeling. I eventually gave up, and ate some xanax to try and come down from the coke and kill the trip. I ended up just sitting there feeling so physically uncomfortable and restless until I was able to sleep. More xanax was needed.
summary:
cocaine + LSD = 
Do them separately. IMO cocaine is best left to be done alone except with alcohol. I don't even like to smoke weed when I do coke (and I smoke lots of weed on any drug), so take that with as many grains of salt as you wish.
Maybe that's why I don't do coke that much...
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baaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaammmm http://www.youtube.com/watch?v=pVZBTAYm3rw
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blazenn
rawdog the whale.


Registered: 05/13/09
Posts: 4,584
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its obvious you particularly don't like coke, i wouldn't expect you to like it on lsd in fact i'd imagine quite the opposite would happen. and the same goes for everybody else here that still keeps fucking saying "the 2 DO NOT go to together, therefore it's a BAD combination for EVERYONE"
idc about which one blocks which fucking receptors, those factors do not go through my mind when i'm frying, and for the record it's very rare that i'm even around coke. haven't seen it in person in over a year, none of my friends ever do it. hell im prolly the only person in my current group of friends that used to do it.
im just sick of people saying so confidently that nobody can enjoy coke + lsd just because they themselves don't even like coke. NO SHIT SHERLOCK OF COURSE YOU WONT LIKE LSD AND COKE IF YOU DONT EVEN FUCKING LIKE COKE!!!!!!!!!!!11!!!!!!111111!!!1FUCKINGONE
not everybody likes dxm, not everybody likes weed, not everbody likes getting drunk for god sakes.
how can people be so fucking judge mental on this forum sometimes? i swear, some people on here act so peaceful and accepting of things they agree with then you bring up the topic of cocaine and everybody's like NOPE NOT GOOD DONT DO IT NOPE NO ONE CAN ENJOY IT CUZ IT'S BAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAD
gtfo you fucking 1970s propoganda believing fools.
(this post is to everyone not just the person i quickreplied)
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PsilocybinMike
T.F.Y.Q.A


Registered: 02/18/08
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Re: LSD and Cocaine... [Re: blazenn]
#13395268 - 10/27/10 01:20 PM (13 years, 3 months ago) |
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Quote:
blazenn said: its obvious you particularly don't like coke, i wouldn't expect you to like it on lsd in fact i'd imagine quite the opposite would happen. and the same goes for everybody else here that still keeps fucking saying "the 2 DO NOT go to together, therefore it's a BAD combination for EVERYONE"
idc about which one blocks which fucking receptors, those factors do not go through my mind when i'm frying, and for the record it's very rare that i'm even around coke. haven't seen it in person in over a year, none of my friends ever do it. hell im prolly the only person in my current group of friends that used to do it.
im just sick of people saying so confidently that nobody can enjoy coke + lsd just because they themselves don't even like coke. NO SHIT SHERLOCK OF COURSE YOU WONT LIKE LSD AND COKE IF YOU DONT EVEN FUCKING LIKE COKE!!!!!!!!!!!11!!!!!!111111!!!1FUCKINGONE
not everybody likes dxm, not everybody likes weed, not everbody likes getting drunk for god sakes.
how can people be so fucking judge mental on this forum sometimes? i swear, some people on here act so peaceful and accepting of things they agree with then you bring up the topic of cocaine and everybody's like NOPE NOT GOOD DONT DO IT NOPE NO ONE CAN ENJOY IT CUZ IT'S BAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAD
gtfo you fucking 1970s propoganda believing fools.
(this post is to everyone not just the person i quickreplied)
What about my response gave you the impression I don't like coke? Of course I like coke, or I wouldn't have done it 15-20 times or so over the course of 6-7 years. Every time I've done it it wasn't just a little bit, we'd stay up all night and do a lot. The reason I tend to avoid it is because it is possibly the worst drug (to my knowledge) to come off of and it just gives you that more more more feeling.
If anyone wants to come by and chop me up a couple fat rails of (relatively) pure cocaine then I'm all for it. I will even serve snacks and refreshments.
p.s
I really admire your style of writing. Do mommy and daddy know you're using their computer on an 18+ website?
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baaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaammmm http://www.youtube.com/watch?v=pVZBTAYm3rw
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blazenn
rawdog the whale.


Registered: 05/13/09
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umm probably that first line......."Seriously. I am not a huge fan of coke "
and this "I had that "I can't fucking wait for this trip to end" feeling but at the same time I still felt like doing more coke, cause that's what coke does.
Anyway as I continue to do more coke, no matter how much I do, I can still not shake that feeling. "
ive had that feeling all night of wanting more blow (who hasnt?) but it's never affected me negatively, well cept for a night that me and my cousin got a ball and we were going through it pretty fast and at one point i had a really strange feeling in my head and my heart and thought for a second i might be OD'ing (LOL) i didnt have a problem stopping snorting that night tho and i honestly have never had a problem stopping when i want to, after one more . but idk being a pothead first and foremost always helped me out with any negative parts of coke, whenever i was ready to pass out id roll a fat j and do just that.
i understand cokes not for everyone and i'm in no way recommending anyone to try it, the addiction side of it is FUCKED UP but that doesn't mean it can't be used responsibly. cause i have used it responsibly, never regularly, only occasionally through the past few years.
i just hate to hear people use their own experiences to say EVERYBODY else will react the same way they did, it's just absurd.
im done w/ the essays now, all the talking's makin me feel like a cokehead
Edited by blazenn (10/27/10 01:27 PM)
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PsilocybinMike
T.F.Y.Q.A


Registered: 02/18/08
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Re: LSD and Cocaine... [Re: blazenn]
#13395291 - 10/27/10 01:26 PM (13 years, 3 months ago) |
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Quote:
blazenn said: umm probably that first line......."Seriously. I am not a huge fan of coke "
The "Seriously." was in reference to "AlmostAsCoolAs"'s response, and once again the only reason I'm not a huge fan of coke is because I like it a little too much and end up going to the ATM at 3 in the morning to buy another gram of coke. It's also probably the most adulterated drug you can buy, good luck finding pure cocaine. I'd much rather spend my money on some pure MDMA or LSD then stepped on street coke.
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baaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaammmm http://www.youtube.com/watch?v=pVZBTAYm3rw
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MushMushMcGee
Stranger

Registered: 03/08/10
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SquaReSaltine said: Personally, do LSD one night, then the next night, take about 4-6 shots, then start sniffing.
Cocaethylene is formed in vivo when cocaine and ethyl alcohol have been ingested simultaneously.[1] Cocaethylene appears to, in most users, produce more euphoria and possess a longer duration of action than cocaine. Some studies suggest that it may be more cardiotoxic than cocaine. Cocaethylene is more potent than cocaine at binding to the dopamine transporter, however it is less potent at binding to the serotonin transporter and norepinephrine transporter.[3][4]
Doing it like this, you get to enjoy the high more, not scramble for another line every 10 minutes.
This is an extremely useful post. I'd never heard of this before, but it makes a lot of sense. I also see how it would slow down your consumption of blow.
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MCSteveyC
lib lover



Registered: 08/23/09
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Here we go again! lol
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Bassfreak
ManBearPig



Registered: 08/24/10
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13544697 - 11/26/10 04:26 PM (13 years, 2 months ago) |
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MCSteveyC said: Here we go again! lol

haha thats whats up dude...i recently ate some of the cleanest L ive ever taken...such a clear headed trip with crazy ass visuals, very audio trip as well...and i also was blowing lines of coke (a few of them mixed with molly) and it was some of the best coke ive blown in a while...my face was so numb and since i was trippin really hard i was walking around literally thinking "wheres my face?" cuz i didnt feel like i had one...hahha love that feeling
i also like coke and doses cuz i feel like it makes it easier to talk to people when ur trippin balls cuz face it, shit gets weird when ur only dosed, adding coke to the mix makes me much more sociable...half the time when someone is talking to me when im dosed im not paying attention to what they say at all cuz i cant focus lol
-------------------- Tom Brady is a God Free Tom Brady
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MCSteveyC
lib lover



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Re: LSD and Cocaine... [Re: Bassfreak]
#13548455 - 11/27/10 02:21 PM (13 years, 2 months ago) |
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lol im still smashed mate!
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blazenn
rawdog the whale.


Registered: 05/13/09
Posts: 4,584
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Quote:
PsilocybinMike said: It's also probably the most adulterated drug you can buy, good luck finding pure cocaine. I'd much rather spend my money on some pure MDMA or LSD then stepped on street coke.
this is very true, and pretty much the main reason that i haven't even touched blow since i moved out of texas. i have a hard time believing anything over 50% purity makes it as far north as i am now.
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Bassfreak
ManBearPig



Registered: 08/24/10
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Re: LSD and Cocaine... [Re: blazenn]
#13549692 - 11/27/10 07:20 PM (13 years, 2 months ago) |
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blazenn said:
Quote:
PsilocybinMike said: It's also probably the most adulterated drug you can buy, good luck finding pure cocaine. I'd much rather spend my money on some pure MDMA or LSD then stepped on street coke.
this is very true, and pretty much the main reason that i haven't even touched blow since i moved out of texas. i have a hard time believing anything over 50% purity makes it as far north as i am now.
yeah i feel that man...i wouldnt doubt it either...im from boston and ive defietly got some FIRE blow before but ive def got straight shit before too...greedy dealers dude, as if u dont make enough money from coke already
i mean even one of my best friends cuts his coke up...but thank god i get to him before he has the time to do that, cuz half the time im with him when he gets it
but i got a friend in texas and he says the blow there is soooo much better than the blow we get here...i mean i dont do much blow and i could easily blow 2 grams of yay in a nite...if i was getting coke like the stuff in texas im sure id have a problem with blowing one gram
but hey some coke is better than no coke, usually...
-------------------- Tom Brady is a God Free Tom Brady
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Shady Obscurity
Getting out of Sour Milk Sea



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Re: LSD and Cocaine... [Re: willo]
#13549754 - 11/27/10 07:33 PM (13 years, 2 months ago) |
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willo said: Well this isn't a good idea because coke will make you very fiendish and you'll probably end up doing too much of it ruining your trip.
Having said this I did a meth/lsd combo which was really fun, so I suppose it would be possible to do it with coke too. I personally wouldn't because as I said coke just clouds your judgment and you might end up having delusions about the trip.
Hope to deter you from doing stupid amounts of drugs and ending up not having a good time.
Whoa... meth? Not even once.
-------------------- The love you take is equal to the love you make.  
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L.S.Ste
Dr Acid



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Re: LSD and Cocaine... [Re: MCSteveyC]
#13783160 - 01/13/11 09:44 PM (13 years, 17 days ago) |
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Lol good combo made me a bit paranoid last time i had it!
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Compaq12986
Stranger


Registered: 12/31/10
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Re: LSD and Cocaine... [Re: Bassfreak]
#13783906 - 01/13/11 11:54 PM (13 years, 17 days ago) |
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Bassfreak said:
Quote:
blazenn said:
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PsilocybinMike said: It's also probably the most adulterated drug you can buy, good luck finding pure cocaine. I'd much rather spend my money on some pure MDMA or LSD then stepped on street coke.
this is very true, and pretty much the main reason that i haven't even touched blow since i moved out of texas. i have a hard time believing anything over 50% purity makes it as far north as i am now.
yeah i feel that man...i wouldnt doubt it either...im from boston and ive defietly got some FIRE blow before but ive def got straight shit before too...greedy dealers dude, as if u dont make enough money from coke already
i mean even one of my best friends cuts his coke up...but thank god i get to him before he has the time to do that, cuz half the time im with him when he gets it
but i got a friend in texas and he says the blow there is soooo much better than the blow we get here...i mean i dont do much blow and i could easily blow 2 grams of yay in a nite...if i was getting coke like the stuff in texas im sure id have a problem with blowing one gram
but hey some coke is better than no coke, usually...
For one if you did more than two lines of pure 100% coke you'd probably die. Most people wouldnt even recoginize pure coke if they saw it. and SWIM can attest to the fact that after he gets an ounce he's making his profit regaurdless of the quality. SWIM has put all kinds of crazy stuff in a bunk or terrible batch to make it buyable. Such as ADD medication and benzocaine.
-------------------- dey see me trollin dey hatin dey moderatin tryna catch me poastin dirty
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Bassfreak
ManBearPig



Registered: 08/24/10
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Quote:
Compaq12986 said:
Quote:
Bassfreak said:
Quote:
blazenn said:
Quote:
PsilocybinMike said: It's also probably the most adulterated drug you can buy, good luck finding pure cocaine. I'd much rather spend my money on some pure MDMA or LSD then stepped on street coke.
this is very true, and pretty much the main reason that i haven't even touched blow since i moved out of texas. i have a hard time believing anything over 50% purity makes it as far north as i am now.
yeah i feel that man...i wouldnt doubt it either...im from boston and ive defietly got some FIRE blow before but ive def got straight shit before too...greedy dealers dude, as if u dont make enough money from coke already
i mean even one of my best friends cuts his coke up...but thank god i get to him before he has the time to do that, cuz half the time im with him when he gets it
but i got a friend in texas and he says the blow there is soooo much better than the blow we get here...i mean i dont do much blow and i could easily blow 2 grams of yay in a nite...if i was getting coke like the stuff in texas im sure id have a problem with blowing one gram
but hey some coke is better than no coke, usually...
For one if you did more than two lines of pure 100% coke you'd probably die. Most people wouldnt even recoginize pure coke if they saw it. and SWIM can attest to the fact that after he gets an ounce he's making his profit regaurdless of the quality. SWIM has put all kinds of crazy stuff in a bunk or terrible batch to make it buyable. Such as ADD medication and benzocaine.
first of all...i never said ive blown pure coke before
and second of all....get the fuck outta here, SWIM? are u serious? pfffffffffffft
-------------------- Tom Brady is a God Free Tom Brady
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