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Bassfreak
ManBearPig



Registered: 08/24/10
Posts: 18,014
Last seen: 8 years, 5 months
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Re: LSD and Cocaine... [Re: Mr.Al] 1
#13373554 - 10/22/10 08:45 PM (13 years, 3 months ago) |
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Quote:
Mr.Al said:
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MCSteveyC said: So tomorrow's the night! Im gettin a fair few hits of Lucy and im going halves with my mate on an 8th of decent coke! Not too sure what these to drugs are like mixed.. Has anyone ever done this?? Shall i mix them, or wait till the acid has worn off before hitting the sniff?? Oh decisions decisions...
L.S.D. could send your blood pressure up significantly. Cocaine definitely would increase your heart rate.
I don't recommend combining these drugs as that may have serious adverse reactions for the heart.
so whats your opinion on a candyflip? ecstasy and coke are very similar drugs
hinestly its better for you to mix various uppers than mixing uppers and downers
honestly u guys are all just being paranoid...ur not gonna OD on coke unless u do a bunch...im a novice coke user (ive used it a handful of times, usually in concert/rave/party situations) and ive railed a couple grams to my dome on nights before while on other drugs which obviously includes acid (and xtc and K)
idk what u guys are thinking...mixing drugs is great...not exactly responsible but u just gotta know ur limits...doin a speedball is way more dangerous than coke and lsd, but plenty of people speedball
-------------------- Tom Brady is a God Free Tom Brady
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Bruce6000
DaGoodDaBombDaBuddha


Registered: 07/04/08
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Re: LSD and Cocaine... [Re: Bassfreak]
#13373948 - 10/22/10 10:17 PM (13 years, 3 months ago) |
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both LSD and cocaine affect serotonin. Cocaine affects a few more neurotransmitters, dopamine is one, I forget the other.
So wouldn't that make them both uppers?
-------------------- Nothing can enslave you other than your unguided attention
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: Bruce6000]
#13373987 - 10/22/10 10:28 PM (13 years, 3 months ago) |
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The most extensively studied effect of cocaine on the central nervous system is the blockade of the dopamine transporter protein. Dopamine transmitter released during neural signaling is normally recycled via the transporter; i.e., the transporter binds the transmitter and pumps it out of the synaptic cleft back into the presynaptic neuron, where it is taken up into storage vesicles. Cocaine binds tightly at the dopamine transporter forming a complex that blocks the transporter's function. The dopamine transporter can no longer perform its reuptake function, and thus dopamine accumulates in the synaptic cleft. This results in an enhanced and prolonged postsynaptic effect of dopaminergic signaling at dopamine receptors on the receiving neuron.
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MDMA acts as a releasing agent of serotonin, norepinephrine, and dopamine.[42] It enters neurons via carriage by the monoamine transporters.[42] Once inside, MDMA inhibits the vesicular monoamine transporter, which results in increased concentrations of serotonin, norepinephrine, and dopamine into the cytoplasm,[43] and induces their release by reversing their respective transporters through a process known as phosphorylation.[44] It also acts as a weak 5-HT1 and 5-HT2 receptor agonist, and its more efficacious metabolite MDA likely augments this action.
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MCSteveyC
lib lover



Registered: 08/23/09
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Re: LSD and Cocaine... [Re: Austrip]
#13374206 - 10/22/10 11:38 PM (13 years, 3 months ago) |
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Quote:
Mr.Al said:
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MCSteveyC said: So tomorrow's the night! Im gettin a fair few hits of Lucy and im going halves with my mate on an 8th of decent coke! Not too sure what these to drugs are like mixed.. Has anyone ever done this?? Shall i mix them, or wait till the acid has worn off before hitting the sniff?? Oh decisions decisions...
L.S.D. could send your blood pressure up significantly. Cocaine definitely would increase your heart rate.
I don't recommend combining these drugs as that may have serious adverse reactions for the heart.
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SuicideCommando said: LSD can expand the mind and open you to new ways to think. Coke does nothing but destroy.
Quote:
Austrip said: Quote:
The most extensively studied effect of cocaine on the central nervous system is the blockade of the dopamine transporter protein. Dopamine transmitter released during neural signaling is normally recycled via the transporter; i.e., the transporter binds the transmitter and pumps it out of the synaptic cleft back into the presynaptic neuron, where it is taken up into storage vesicles. Cocaine binds tightly at the dopamine transporter forming a complex that blocks the transporter's function. The dopamine transporter can no longer perform its reuptake function, and thus dopamine accumulates in the synaptic cleft. This results in an enhanced and prolonged postsynaptic effect of dopaminergic signaling at dopamine receptors on the receiving neuron.
Quote:
MDMA acts as a releasing agent of serotonin, norepinephrine, and dopamine.[42] It enters neurons via carriage by the monoamine transporters.[42] Once inside, MDMA inhibits the vesicular monoamine transporter, which results in increased concentrations of serotonin, norepinephrine, and dopamine into the cytoplasm,[43] and induces their release by reversing their respective transporters through a process known as phosphorylation.[44] It also acts as a weak 5-HT1 and 5-HT2 receptor agonist, and its more efficacious metabolite MDA likely augments this action.
blah blah
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stuntmanmike



Registered: 09/16/10
Posts: 836
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13376877 - 10/23/10 04:18 PM (13 years, 3 months ago) |
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I don't think LSD and coke are good companions, the last thing you need with hallucinations is confidence.
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Bassfreak
ManBearPig



Registered: 08/24/10
Posts: 18,014
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Quote:
stuntmanmike said: I don't think LSD and coke are good companions, the last thing you need with hallucinations is confidence.
yeah...but like you and more than half the people posting in this thread...u have no idea what its like to do em both...leave it to the people with actual experience with this mixture
the only people saying this is a bad combo are people who havent done it and its annoying as fuck cuz all it is, is speculation...in reality none of you have any idea at all...its a great and fun mix
-------------------- Tom Brady is a God Free Tom Brady
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MCSteveyC
lib lover



Registered: 08/23/09
Posts: 848
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Re: LSD and Cocaine... [Re: Bassfreak]
#13386964 - 10/25/10 08:05 PM (13 years, 3 months ago) |
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Well trip report.. I started off with taking a good few trips, it kind of started off mild, i was just led in bed for the first hour watchin telly, in time things just got worse and my room went crazy everything was moving erratically. At that point i thought, "i don't need anymore" i was really enjoying it. I tripped out for about 2 hours then i decided after reading these comments on this thread i would try a line. So i did. I loved it, it sorted my head out a bit but i was still tripping my tits off, so i carried on put my headphones on and i enjoyed every min of it! I finished off my coke about 6am, took an E, and done the rest of the trips. My Mrs came round and I sat up all saturday day talkin bollocks to her, shagging, and ended up gettin a takeaway. The trip gently descended i got sleepy and went to sleep! It was brilliant! Can't wait to do it again! Nowt wrong wi doin a few lines wi acid! Its class!
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387014 - 10/25/10 08:17 PM (13 years, 3 months ago) |
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Wait so you ate all of that acid? or am I reading this wrong??
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MCSteveyC
lib lover



Registered: 08/23/09
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Re: LSD and Cocaine... [Re: Austrip]
#13387038 - 10/25/10 08:22 PM (13 years, 3 months ago) |
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Yeah i ate the lot....i was messy!
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Austrip
P. Sub


Registered: 08/05/10
Posts: 1,247
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387060 - 10/25/10 08:25 PM (13 years, 3 months ago) |
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whoa that's massive dude! wasn't there like 50 hits there? That's like 2 or 3 years worth of cid for me.
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MCSteveyC
lib lover



Registered: 08/23/09
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Re: LSD and Cocaine... [Re: Austrip]
#13387075 - 10/25/10 08:28 PM (13 years, 3 months ago) |
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There was 40.... i started off by taking 16 thats when my brain melted, but when i took some coke it straightened my head so i took another 12 and at the end another 12... i was trppin till sunday
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TripJunkie
Stranger

Registered: 05/14/07
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387156 - 10/25/10 08:41 PM (13 years, 3 months ago) |
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my friend said when he was having a bad trip that cocaine helped him
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MCSteveyC
lib lover



Registered: 08/23/09
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Re: LSD and Cocaine... [Re: TripJunkie] 1
#13387278 - 10/25/10 09:01 PM (13 years, 3 months ago) |
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Everyone who has said LSD and cocaine is a bad idea is completely wrong! I fuckin loved every min of it!
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cryptix420
Psilocybinatic



Registered: 03/17/10
Posts: 210
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387303 - 10/25/10 09:06 PM (13 years, 3 months ago) |
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i just feel that cocaine is a bad idea
i feel like i already know how it's going to feel without having ever done it. i don't feel very pulled towards things that feel like dead ends, know what i mean jellybeans
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MCSteveyC
lib lover



Registered: 08/23/09
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if u aint ever done it you can't judge it!!!!
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drr


Registered: 05/20/09
Posts: 8,444
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387527 - 10/25/10 09:48 PM (13 years, 3 months ago) |
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I've done it. It is a bad idea. Stick with your instincts. That drug has never done any real good for anybody.
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cryptix420
Psilocybinatic



Registered: 03/17/10
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Re: LSD and Cocaine... [Re: MCSteveyC]
#13387762 - 10/25/10 10:41 PM (13 years, 3 months ago) |
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Ey man I'm not judging anyone. Just for my own reasons...you know, loving drugs/getting fucked up/having an addictive personality...
coke doesn't seem like a crutch i need to give myself. fuckin' with dopamine scares me...those systems can't reset like serotonin
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MetalMachineMusic
Stranger


Registered: 10/03/10
Posts: 162
Loc: Darlington
Last seen: 12 years, 4 months
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I can't believe you gobbled 16 hits off acid in a oner, that's offit.
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WordsWorth
More trees then Christmas

Registered: 10/31/07
Posts: 97
Loc: Compton
Last seen: 11 years, 8 months
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I once snorted a fat .2 line of ICE and walked home to find my room mate sitting there with 3 hits of White-on-White for me..
Never in my life have i been that far. It was a ride
-------------------- Freak the establishment
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7yler

Registered: 10/24/10
Posts: 140
Last seen: 9 years, 20 days
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liquor + cocaine + ADHD = temporarily insane..
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