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OfflinePsuper
Psilocybin


Registered: 02/12/08
Posts: 2,875
Loc: PNW
Last seen: 7 days, 21 hours
Mushroom With Enhanced Vitamin D2 Naturally Suppresses Alzheimer's Disease in a Clinical Model
    #13258086 - 09/28/10 08:46 AM (13 years, 7 months ago)

http://finance.yahoo.com/news/Mushroom-With-Enhanced-pz-953464551.html?x=0&.v=1

Mushroom With Enhanced Vitamin D2 Naturally Suppresses Alzheimer's Disease in a Clinical Model

Total Nutraceutical Solutions Files U.S. and Worldwide Clinical Use Patents
Press Release Source: Total Nutraceutical Solutions Inc. On Tuesday September 28, 2010, 9:30 am EDT

STEVENSON, Wash., Sept. 28, 2010 (GLOBE NEWSWIRE) -- Total Nutraceutical Solutions, Inc. (TNS) (OTCBB:TNUS - News), announced today that a mushroom under study by TNS was found to have the ability to suppress and prevent Alzheimer's disease (AD). A classic transgenic model of AD was used in which the brain produces increased amounts of the toxic neurodegenerative protein, called amyloid. Amyloids are insoluble fibrous protein aggregates that have been implicated in the development of various neurodegenerative diseases, including Alzheimer's disease. The clinical study was performed at an independent biotech research center owned by Model BioSystems, Inc of San Clemente, California and Bangalore, India. A transgenic AD fruit fly (Drosophila melanogaster) model was used to evaluate effects of various test substances including natural whole mushroom powders. The genetically modified fruit fly over expresses and over produces amyloid within its brain tissues and is a well accepted model of human neurodegenerative disorders such as Alzheimer's disease. This AD strain lives for only a few days after birth as opposed to 65 days or more for wild type normal strains.



TNS, a global biotechnology leader in whole food mushroom research, tested the ability of edible specialty mushrooms under proprietary development (patent pending), with and without naturally enhanced levels of organic Vitamin D2, to extend the lifespan of the Alzheimer's disease mutant fruit fly. Synthetic vitamin D2 and synthetic Vitamin D3 were also individually tested as well as added to unenhanced mushroom test powders. A specific mushroom, Agaricus blazei Murrill (AbM), with enhanced levels of natural organic vitamin D2 dramatically suppressed and prevented Alzheimer's disease. Synthetic Vitamin D2 marginally improved survival of the AD flies, while synthetic Vitamin D3 worsened survival. Also of interest was the finding that synthetic Vitamin D2 became protective when added to natural AbM powder; added synthetic Vitamin D3 showed only marginal improvement in survival. These evidence based nutritional findings may represent the first time that a natural organic food has been shown to have the potential to suppress and prevent a neurodegenerative disorder, such as Alzheimer's disease. Statistically significant findings also reveal a physiologic difference between activity of synthetic forms of Vitamin D2 and Vitamin D3 in this neurodegenerative disease model. Study results suggest that neurons may have both Vitamin D2 and Vitamin D3 receptors and that these neuronal cell receptors may be more responsive to Vitamin D2 as compared to Vitamin D3. TNS ongoing research may uncover further significant findings.



"Alzheimer's disease has become one of mankind's most devastating diseases and the potential ability of a natural whole food to suppress and prevent this disease is a remarkable finding," stated Marvin S. Hausman MD, CEO, TNS. "There has been minimal progress over the past 10 years in the development of AD preventive drugs. Our company is moving quickly to produce a mushroom-based product with naturally enhanced levels of vitamin D2 for human dietary nutritional use."



About Total Nutraceutical Solutions, Inc.:



TNS, a global biotechnology leader in whole food mushroom research and development, focuses on discovering, formulating and marketing products composed primarily of organic natural whole mushroom foods, containing bioactive nutrients, such as L-Ergothioneine and Vitamin D, with potential health benefits. Our scientific strategy is to specialize in the development of production and analytic technologies for food and nutritional supplements mainly composed of mushrooms and their mycelial biomasses. Novel clinical models and biomarkers are used to show nutritional and clinical efficacy of our products. In addition to our novel preventative healthcare formulations and nutritional approaches for a wide variety of human conditions and illnesses, we are also involved in the development, acquisition and ownership of breakthrough nutritional tools and products in the fields of animal husbandry and livestock feeds.



The Total Nutraceutical Solutions, Inc. logo is available at http://www.globenewswire.com/newsroom/prs/?pkgid=8060


Any statements contained in this press release that relate to future plans, events or performance are forward-looking statements that involve risks and uncertainties, including, but not limited to, the risks associated with the transaction described in this press release, and other risks identified in the filings by Total Nutraceutical Solutions (TNS), Inc., with the Securities and Exchange Commission. Further information on risks faced by TNS are detailed in the Form 10-K for the year ended December 31, 2009, and in its subsequent Quarterly Reports on Form 10-Q. These filings are or will become available on a website maintained by the Securities and Exchange Commission at http://www.sec.gov. The information contained in this press release is accurate as of the date indicated. Actual results, events or performance may differ materially. TNS does not undertake any obligation to publicly release the result of any revision to these forward-looking statements that may be made to reflect events or circumstances after the date hereof or to reflect the occurrence of unanticipated events.






Contact:
Total Nutraceutical Solutions, Inc.Roberta Matta509-427-5132www.totalnutraceutical.com


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Offlinecurenado
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Registered: 04/01/03
Posts: 2,663
Loc: North Central Arkansas
Last seen: 1 hour, 56 minutes
Re: Mushroom With Enhanced Vitamin D2 Naturally Suppresses Alzheimer's Disease in a Clinical Model [Re: Psuper]
    #13259214 - 09/28/10 01:28 PM (13 years, 7 months ago)

This is a add for people to buy turkey tails? They are the most prevalent mushroom in nature and a rich source of provitamin D2...
I think I'll try to find out more about this because it sounds like a sales pitch. In the US you can't patent a organic - maybe you can sun drying them to increase the PV D2?

It took a whole page to say "We grow turkey tails out, dry the substrate with the mushrooms and grind it to powder. We "naturally" increase the Vitamin D2 levels by throwing the batch out in the sun to roast dry and grind away!"

I mean, that is all it actually sounds like. I have a friend that can program feed a mushroom to fit a condition, and I bet he :lol: about that. Maybe I am wrong but I will ask.

It just looks like "Hey! Sun dry them tails and not only will it suppress and protect from cancer it will preserve ye brains too! Oh! There's also more stuff in the whole biomass, so grow them on rice or something good to eat."
Stamets grows his out on brown rice, dires and grinds the whole thing.

I have a solar powered vitamin D increaser for mushrooms! like turkey tails and shittake. It works good as long as someone doesn't need it to drive to town in......
:smilingpuppy:

Plus ALL doctors know that the natural, organic forms of Vit D are MUCH more absorbable by the body, that's why they tell people to use more than the bottle says if they buy it at Wally's instead of eating.....turkey tails....sun dried :cool:


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Yours in the Natural State Land of Enchantment!
"The woods are lovely, dark and deep; but I have patches to keep, and jars to sterilize before I sleep...."

"When psychotomimetics become cultural, so does cultural psychosis"

Edited by curenado (09/28/10 01:50 PM)

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InvisibleveggieM

Registered: 07/25/04
Posts: 17,538
Re: Mushroom With Enhanced Vitamin D2 Naturally Suppresses Alzheimer's Disease in a Clinical Model [Re: curenado]
    #13260158 - 09/28/10 04:27 PM (13 years, 7 months ago)

You're right, this is a press release from Total Nutraceutical Solutions so it is in effect an advertisement for themselves. It doesn't mention turkey tails, but they also have a long history of medicinal use.

Companies have been selling Vit. D enhanced mushrooms for a couple of years at least and you can by them fresh in the market. I think to say their mushroom supplements prevent Alzheimer's disease may be a bit overstated. But certainly increasing the amount of mushrooms in your diet as well as Vit. D should be encouraged.

Personally, I would prefer to use products that do not do animal testing.

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