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Mushrooms, Mycology and Psychedelics > The Psychedelic Experience
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San Pedro and Syrian Rue
    #1238710 -

Hello,
I have been unable to find out if using mescaline in combination with rue is dangerous.  I heard that it contains amphetamines and thus, should not be combined with rue.  I also read two trip reports of people who did the mix and had very positive trips, without listing any negative effects.
If anyone has any insight into this issue, that can help resolve this mystery, your contribution is much appreciated.

Thanks. :wink:


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #1238769 -

I think K Trout mentioned something about the mixing of phenethylamines and MAOI's being a risk because of the potential of hypertensive crisis. He's not convinced it will cause problems, just suggests it's probably not a good idea.


--------------------
Don't worry, B. Caapi

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Re: San Pedro and Syrian Rue [Re: Xlea321]
    #1238775 -

But is mescaline a phenethylamine? or does it have other phenethylamine components in it?

Does anyone know for sure?


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #1238803 -

Mescaline is a phenethylamine.


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Don't worry, B. Caapi

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #1238812 -

If Trout doesn't know I don't think anyone does. Why do you want to mix the MAOI with it? Have you heard it potentiates the effects at all?


--------------------
Don't worry, B. Caapi

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Re: San Pedro and Syrian Rue [Re: Xlea321]
    #1238819 -

I just read two trip reports at erowid and now i am very intrigued!!

Check em out!  Seems it was a wonderful mix...

http://www.erowid.org/experiences/exp.php3?ID=2374

http://www.erowid.org/experiences/exp.php3?ID=20166

These reports are why i thought it would work... :laugh:


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #1238826 -

Also i was contemplating making a modified ayahausca.

Milmolosa Bark (however you spell it)
Syrian Rue
Hawian baby woodrose seeds
Shrooms
San pedro
and mabye even that capri vine maoi....

Just a thought i had..........It would one crazily psycoactive brew :crazy:  I wouldn't think of trying it until i've had much experience with all the additives...


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #1239608 -

Sounds interesting man but I'd check your nausea levels with san pedro first! Just san pedro by itself in the form of dried capsules gave me serious nausea for a good 9 hours. I can't imagine having ayahuasca on top of it  :crazy:


--------------------
Don't worry, B. Caapi

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Re: San Pedro and Syrian Rue [Re: Xlea321]
    #1242265 -

I thought more people would have tried san pedro and rue...
Seems like a pretty interesting combo!


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #1242451 -

reason is you really don't need to potentiate the mesc any further, pedro is mindblowing in his own right! if i'm going to push it, i like to mix pedro with shrooms and/or E, done it with excellent results several times.


--------------------
comario


"crusaders against emotional poverty"

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Re: San Pedro and Syrian Rue [Re: comario2]
    #1242540 -

But people are always complaining about the taste.  Mixed with rue you prolly would only need to consume half the cactus gunk you normally would need to.  Thats good to know it goes with shrooms well! :grin:


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

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Re: San Pedro and Syrian Rue [Re: comario2]
    #1242543 -

...


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

Edited by Azmodeus (01/23/03 09:07 AM)

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #1245927 -

I wouldn't risk taking a MAOI with Mescaline.  I have (unfortunately) seen the effects of MDMA + MAOI and it was not pretty at all, and I believe that MDMA and Mescaline are both phenethylamine's... save the Rue for use with psychedelics: LSD, Shrooms, or best of all DMT  :cool: 


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"Reality is an illusion caused by lack of shrooms" - All posts are fictional - Read at your own risk

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Re: San Pedro and Syrian Rue [Re: azzid]
    #1245976 -

So did anyone read the trip report links i posted?  What could explain that! :confused:


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #1247752 -

Hey, do it if you want, I don't know what to tell you but I don't plan on doing it because people who seem to know stuff say it's a dangerous combination. If you doubt this and think it's probaby safe because of these trip reports on erowid then consider this: Why don't south american shamans mix caapi with san pedro? Of course the plants grow in different climates but people can move around and I'm sure there have been ayahuasqueros in the past who knew about san pedro, so why didn't they mix it in the brew? If it gives such kickass trips and is so safe and healthy don't you think it would be a traditional concoction? I'm not doin it

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Re: San Pedro and Syrian Rue [Re: Dogomush]
    #1252126 -

Good point!! Yeah, responces have been pretty inconclusive on this one. Quite a few people say its not safe, but the only real evidence i had for the combo were those trip reports which doesnt really tell me shit.

I think mabye in summer time i might try this combo, but only in extremely low doses, i will have to research it more though before i'd even do that, but if someone can shed any light onto this topic your comments are still welcome.


--------------------
"Know your Body - Know your Mind - Know your Substance - Know your Source.

Lest we forget. "

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #24253077 -

Azmodeus said:
I thought more people would have tried san pedro and rue...
Seems like a pretty interesting combo! 


I have been instructed by my shaman to take SP extract and Syrian Rue. i made a post about it a month or so ago. just stumbled upon this. haven't touched it for many reasons

i have a rare disease and am on serious pharmaceutical medications, some of which i wouldn't be quite sure would go well with Syrian Rue or San Pedro extract in capsule form...

still on the hunt for knowledge before i go that route as cautiously as possible. have heard diet is crucial and that alone is a struggle for me due to undiagnosed GI issues in addition to the progressive pain disease (CRPS)

Edited by crispy86 (04/17/17 10:20 PM)

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #24253787 -

Azmodeus said:
Hello,
I have been unable to find out if using mescaline in combination with rue is dangerous.  I heard that it contains amphetamines and thus, should not be combined with rue.  I also read two trip reports of people who did the mix and had very positive trips, without listing any negative effects.
If anyone has any insight into this issue, that can help resolve this mystery, your contribution is much appreciated.

Thanks. :wink:


This has been verified time and time again by peer vetted & published studies.  SAN PEDRO IS NOT EXPLICITLY SAFE WITH ANY MAOI!  Can it be safe? Certainly, but it may not be.  Things to consider...

1) Mescaline is absolutely safe when mixed with an appropriate dose of MAOIs.
2) San Pedro contains many alkaloids including Tyramine, which has dangerous interactions with MAOIs.
3) San Pedro already contains some quantity of Hordenine, an MAOI.

Therefore, unless you know the exact quantity of Hordenine and Tyramine in your dose, you have no way to determine what dose of supplemental MAOIs will be safe, period.  Good luck and have fun, but please be careful guys.

Edited by Organic Chemist (04/18/17 08:34 AM)

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Re: San Pedro and Syrian Rue [Re: Azmodeus]
    #24254256 -

Azmodeus said:
Also i was contemplating making a modified ayahausca.

Milmolosa Bark (however you spell it)
Syrian Rue
Hawian baby woodrose seeds
Shrooms
San pedro
and mabye even that capri vine maoi....

Just a thought i had..........It would one crazily psycoactive brew :crazy:  I wouldn't think of trying it until i've had much experience with all the additives...


This sounds like a recipe for serotonin syndrome if I ever saw one :lol:

Unless you have a lot of experience with all of those things individually that sounds like a bad idea.

Bridgesii supposedly has MAOI's in it but they are clearly meant to be used with mescaline. Harmalas are not necessarily and could be dangerous.

Just get some nitrous and cannabis if you want something to go with the mescal.


--------------------
Don't worry about me, I've got all that I need. And I'm singing my song to the sky

You know how it feels, With the breeze of the sun in your eyes. Not minding that time's passing by

I've got all and more, My smile, just as before. Is all that I carry with me

I talk to myself, I need nobody else. I'm lost and I'm mine, yes I'm free


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Mushrooms, Mycology and Psychedelics > The Psychedelic Experience
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