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Offlinetony serro
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Re: Experimental research required, in the underground if not the mainstream. [Re: AmericanSpirit]
    #11911616 - 01/27/10 12:49 PM (14 years, 3 days ago)

I kind of figured something like this out myself once when i was on mda, good job. Just one question though: I'm interested in an atypical pyschotic that does ANYTHING to the serotonin system. I don't know much about them but I used to take quetiapine to get to sleep during my days abusing stimulants and as far as I know it is DA antagonist which removes DA from the synapse rather than increase it the way stimulants do. Its also a very interesting experience to take just for the fuck of it. But yea what atypicals are there that fuck with 5-ht?


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The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


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Offlinetony serro
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Male


Registered: 08/20/09
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Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: AmericanSpirit]
    #11916457 - 01/28/10 07:42 AM (14 years, 2 days ago)

Quote:

AmericanSpirit said:
crystal meth contains synthetic adrenaline, so results in a direct increase in adrenaline.




:lol::rofl::lol: Crystal meth contains synthetic adrenaline? Methamphetamine is one chemical fool, it does not "contain" anything other than one or both isomers of methamphetamine and whatever by products result from incomplete synth. Synthetic adrenaline does exist and works only if administered by IV. :facepalm: Methamphetamine also shows pretty high affinity for serotonin release. Not as much as mdma, but yes it does release serotonin and in high doses does have "loved effects." :facepalm:

ADD causes anti sociability? I have ADD and most people I know with the condition have the reverse of this problem.


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


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Offlinetony serro
DEA Agent
Male


Registered: 08/20/09
Posts: 1,508
Loc: Montreal
Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: AmericanSpirit]
    #11917803 - 01/28/10 01:28 PM (14 years, 2 days ago)

:facepalm: Where the hell does what you posted from erowid mention adrenaline getting into methamphetamine, can you quote it please because I did not see it and had to have the misfortune of reading an article on basic chemistry I learned at 16. O and because you would describe a a mostly peripherally acting stimulant as synthethic ANYTHING makes it true? Obviously you don't have a pharmacology or a chemistry degree or you wouldn't be making absurd statements such as saying that ephedrine is synthetic adrenaline. You said there "is adrenaline in methamphetamine". And serotonin and dopamine are interrelated? I can put up arguments for both and won't bother, but go open a medical journal and you'll see that d-meth definitely shows high affinity for releasing serotonin. :facepalm: God...


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


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Offlinetony serro
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Registered: 08/20/09
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Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: tony serro]
    #11917809 - 01/28/10 01:30 PM (14 years, 2 days ago)



Adrenaline.



Ephedrine.

:facepalm::facepalm::facepalm::facepalm::facepalm:


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


Extras: Unfilter Print Post Top
Offlinetony serro
DEA Agent
Male


Registered: 08/20/09
Posts: 1,508
Loc: Montreal
Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: AmericanSpirit]
    #11922597 - 01/29/10 07:08 AM (14 years, 1 day ago)

I wasn't being unfriendly man your just spreading misinformation and are making it sound like you know what your talking about. I'm 18 and have no medical degrees either but I make sure I know I'm right about something before saying it. Maybe sometimes I'm an asshole sorry about that but seriously man research your shit next time before posting...

Quote:

AmericanSpirit said:
People with high dopamine count & low serotonin count tend to react like that




High dopamine count? I told you I have ADD and I'm highly dysfunctional I doubt many people here have lower amounts of DA in their brain than I probably do:smirk: But again your not a neurologist and haven't seen a PET scan of my brain so you shouldn't really be making claims like this... Again sorry if I sounded like a dickhead, that wasn't cool I just hate ignorance especially when it comes to drugs, but it could have been worse, if hpi had seen this...:lol:


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


Edited by tony serro (01/29/10 07:14 AM)


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Offlinetony serro
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Male


Registered: 08/20/09
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Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: AmericanSpirit]
    #11946796 - 02/02/10 09:09 AM (13 years, 11 months ago)

Quote:

AmericanSpirit said:
I'm not extremely well researched on the topic of psychiatry, certainly not enough to give medical advice, but I don't take back my original statement because my opinion hasn't changed - & I never claimed to be an expert in the first place.

From what little I know of ephedrine & pseudoephedrine, there is more an affinity for adrenaline, norepinephrine if not epinephrine, & less an affinity for dopamine, than with cocaine, making pseudoephedrine more likely to directly trigger adrenaline rather than doing so as an indirect consequence of dopamine release. & Since methamphetamine is made from (pseudo)ephedrine, & also because an extremely small amount of online research indicates that it is so, I consider it more probable than not that meth is the same way - meaning meth contains a component of synthetic adrenaline.

(synthetic is defined in many different ways).

I have been attempting to spot check myself on this one, & read at least one credible article from a medical journal indicating that pseudoephedrine has low affinity for dopamine & high affinity for norepinephrine. I also read an article claiming that (pseudo)ephedrine is often confused with epinephrine.

I do not deny that meth can impact serotonin, any more than I would deny that LSD impacts dopamine - LSD impacts dopamine rather dramatically in many cases, probably most trips involve a significant increase in dopamine activity. But meth is primarily a dopamine high, & LSD primarily a serotonin high. I do not consider that an ignorant conclusion. (& meth is probably toxic to serotonin, as mentioned in one of the above posts)

I think it is ok to talk about these things even if you don't have a medical degree - which I have always emphasised about myself, before you saw fit to, over and over again, in what seemed to me to be an egotistical, impulsive, and intolerant manner, point that out. But I also must acknowledge that message board posts are easy to misinterpret - & I could have simply misinterpreted all of those facepalms and the condemning reply made two seconds after I responded to your first condemning remark, while I was in the middle of editing.

I would never ask anyone, "Are you high?" It is an extremely stupid question because the answer is obviously always literally "No." I don't know anybody who uses drugs, and probably very rarely encounter any such person on the internet. But anyone who ever has, for a significant period of time - has plausibly undergone significant brain chemistry changes overtime. I know my brain chemistry is dramatically different, from what it would have been had I never taken drugs.

I also don't presume to tell you what your brain chemistry is.

I appreciate your apology, & in the future I will be a bit more careful how I word my own statements... but I will probably make many, many ill informed statements in the future, by way of casual conversation.




:facepalm: Synthetic, scientifically is defined in one definition. Maybe to you it means something different but if your going to start re-inventing words and then using nonexistant terms to prove your point there is no point arguing with you. Ephedrine is not synthetic anything. It is one molecule, adrenaline is another. Fuck, just admit your wrong, its a goddamn internet forum. I have nothing against your theory I just hate ignorant fkn people who have no source for what they are claiming is scientific fact other than what they heard from other people or fabricated in their own minds.

People who spread misinformation about shit like this need to be thought a lesson. What if someone saw your post on methamphetamine being synthetic adrenaline and reasoned that it IS adrenaline and is no more toxic to the body or mind than shooting real adrenaline? Obviously that could happen because your here posting stuff that you heard god only knows where and are accepting it as fact. Posting something like that is just as ignorant as the whole government scare on methamphetamine containing draino, or lsd making holes in your brain.


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


Edited by tony serro (02/02/10 09:23 AM)


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Offlinetony serro
DEA Agent
Male


Registered: 08/20/09
Posts: 1,508
Loc: Montreal
Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: AmericanSpirit]
    #11959920 - 02/04/10 07:16 AM (13 years, 11 months ago)

Quote:

AmericanSpirit said:
tony serro - I would like to apologise, admit you were right and I was wrong.




Really I don't care that much, just what if people would have believed what you said and thought methamp was the same chemical as the one in their adrenal gland, just made in a lab. Could have fucked up someone's day, it is unlikely but :shrug:


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


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Offlinetony serro
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Registered: 08/20/09
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Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: notapillow]
    #11960485 - 02/04/10 09:30 AM (13 years, 11 months ago)

Really? Are you 100% sure of this? I always knew these plants contained various phens and trypts but I never saw amp/ meth listed.


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


Extras: Unfilter Print Post Top
Offlinetony serro
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Male


Registered: 08/20/09
Posts: 1,508
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Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: notapillow]
    #11960506 - 02/04/10 09:34 AM (13 years, 11 months ago)

Awesome, but theres so many chemicals in there it would be close to impossible to do a proper extraction of just one of them, right?


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


Extras: Unfilter Print Post Top
Offlinetony serro
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Registered: 08/20/09
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Last seen: 10 years, 8 months
Re: Experimental research required, in the underground if not the mainstream. [Re: solstice]
    #11967124 - 02/05/10 07:37 AM (13 years, 11 months ago)

Over reacting?!? OVER REACTING?!?! :kingcrankey: :lol: Nah I'm just joking, sorry people who talk out of their ass when it comes to science or drugs in particular really piss me off and I was in a bad mood already. But if people like me didn't snap, we'd have more of those "LSD puts holes in your brain" type rumors going around...


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


Extras: Unfilter Print Post Top
Offlinetony serro
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Male


Registered: 08/20/09
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Re: Experimental research required, in the underground if not the mainstream. [Re: solstice]
    #11971375 - 02/05/10 06:44 PM (13 years, 11 months ago)

I dont know if thats sarcasm or not but I'm thrashed on k-pins and want to start a fight if it is which one is it :kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey::kingcrankey:


--------------------
The most thoroughly and relentlessly damned, banned, excluded, condemned, suppressed,brutalized and defamed of all Damned Things is the individual human being. The social engineers, are perpetually forcing this Damned Thing into carefully prepared blueprints and perpetually irritated that the Damned Thing will not fit into the slot assigned to it. The theologians call it a sinner and try to reform it The governor calls it a criminal and tries to punish it The psychotherapist calls it a neurotic and tries to cure it. Still, the Damned Thing will not fit into their slots. -Robert Anton Wilson


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